Gene 32425 (M.brevicollis)

32425

Species: M.brevicollis
Alias: 32425
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Myo-SH2

Sequence

Name Sequence Type Origin Length Description Download
32425.AA Protein None 1021 None Fasta, JSON

Protein domain

Protein domains of 32425.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MYSc 32425.AA MYSc 98-710 28 1.6e-170 573.68 SMART 1-771 (771) Show / Hide 
Range on Protein: 98-710
Range on HMM: 1-771/771
Sequence Identity: 28% (231 aa)

AKPWIKGDVDDLASLANLDDSILLEELKTRYFANKIYTYVGDILVAINPFQDL-PLYTKQIKDQYH------DIPKSAAAPHVYAIADQAYHSMISE---
  | .. .|||.. | .| .  .|. || ||  ..|||| |....|.||...| |.||... .||.         ..  .||..|||| ||..| ..   
MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN

-----------------------------------------------------------------------------------YLLERSRVVRQNAGENN
                                                                                   ||||.||||.|| || |
QCIIISGESGAGKTENTKKIMQYLAAVSGQVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGERN

FHVMYYVFAS---PNAAQLGLN----DYRRFNYVSQ-------------CASFP-RDNQGSYNE----VISAFRTVGFSQVEQANVHSMLAAVLHIGNIE
.|. |.  |    .   ...|     .   ..|..|             | . . .| .  . |    ...|.|..|||  ||... . .||.||.||||
YHIFYQLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVDGIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHLGNIE

FEDIYS--TSETPEM--SSPREVLNTAASVLGVDPNALFESIVAVTTVTRGE---TIRRVNTPDKSTDTKNAIAKALYGRLFSWIVSQINNLLAVGSRSR
||.. .   . . ..  .. .|.|..|.. |||||  | ....  ...|..|   .|.. ...   ... .|.|||.|.|||.|||..||  .       
FEQGRNQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM-------

GARLDIGILDIFGFEHFQTNGFEQLCINVANEQLQNFFNQHIFKQELAEYAREGIDGSNITFE--DNQPLLDMCFGK---PIGLFALLDEESRF---PRA
  .. ||.|||.|||.|. |.|||.||| .||.||.|||.|.||.|  || ||||. ..| |   |||| .|   .|   |.|.|.|||||..|   |..
-HNYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECMFHAQPKG

TDDTLIQKL-----KNQLTGQAGYEPA-----------RTSAPCFTIKHYAGAVEYTSYGFLDRNRDELSQDVRKMAQSSSNELVRQLFANDDDDTPRHG
||.|...||     ......   ....           | . ..|.|||||| |.|   |.|..|.| |..|.    |||.|....|||  . |.| ...
TDQTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQTSQTP

G-SSAVQANSA----------------QKRSATVSHQFVADLRLLIDKMMKCMAHFVRCIKPNTEQAPSKFIDDFVNGQLRYTGMLETTRIRREGYSFRP
. .|. |...                  ||  ||. ||   |  |......|  |..|||||| |. | .| || |  |||. |.||. ||||.|...| 
QEKSS-QGKNKSRRKKRMMQMKKTCMQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRW

TFAEFMERFGILAY--GPSAR-------VEASSQTCSKVLAASG---------VKGWLVGKTKASMSLGLIMFECCNSAVVFLK-YWQVEQLDKSIKL
...||..|...|.    |. .        .   . | ..| ..|          ... .||||                 ||.. . |.. |..  . 
PYQEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTK-----------------VFFRNPGQLFHLEEMRER
Myosin_head 32425.AA Myosin_head 185-676 29 3e-148 503.58 Pfam 176-761 (765) Show / Hide 
Range on Protein: 185-676
Range on HMM: 176-761/765
Sequence Identity: 29% (174 aa)

ISEYLLERSRVVRQNAGENNFHVMYYVFASPNAAQ----LGLN--DYRRFNYVSQCA---SFPR----DNQGSYNEVISAFRTVGFSQVEQANVHSMLAA
|. ||||.||||.|..|| |||. |.  |. ....    |.|   | ....|..|..   ...     |..  . .. .|....||...||. . . .||
IENYLLEKSRVVYQTPGERNFHIFYQLLAGASQQEEKKELHLTSADPKDYHYLNQSGTNPCYTVDDGIDDAEEFQHTRNAMDIIGFTHEEQRSIFRIVAA

VLHIGNIE-FEDIYSTSETPEMSSPREV-LNTAASVLGVDPNALFESIVAVTTVTR----GETIRRVNTPDKSTDTKNAIAKALYGRLFSWIVSQINNLL
.||.||.. |..  .       ..  |. .. ... .||||  .  ...  . .|.     |.. .  .......  .| |||.|.|.| |||. ||. .
ILHLGNMKGFKQDQNEEQA--VVDDTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRINQAI

AVGSRS---------------------------RGARLDIGILDIFGFEHF-QTNGFEQLCINVANEQLQNFFNQHIFKQELAEYAREGIDGSNITF-ED
 ..  .                           . ... ||.|||.|||.| . |.|||.||| .||.||.|||.|.|| |  || ||||. ..| .  |
CHKTQNTDDSDGQAAQWDDTVSITVVDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFD

NQPLLDMCFG-KPIGLFALLDEESRFPRATDDTLIQKLKNQL-TGQA--GY-EPA-R------TSAPCFTIKHYAGAVEYTSYGFLDRNRDELSQDVRKM
|||  |   . ||.|...|||||..||.|||.|..||| ..     .   . .   |      ... .|.|||||| |.|   |.|. |.| |..|. . 
NQPCCDLIEKKKPMGILSLLDEECWFPKATDQTFLQKLYQTHSSKHPRLHFAQKPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIEL

AQSSSN-ELVRQLFANDDDDTPRH---------------------GGSSAVQANSAQK-RSATVSHQFVADLRLLIDKMMKC---MAHFVRCIKPNTEQA
...|..  ....||  .   . .|                     |.....|. .... .  ||..||   .  |.  . .|    .|.||||||| ...
MWCSWDNPFMQELFPDWEWAEWAHMQIDFEADFHEEEFKRRYNRNGCQKGKQGKKKWFMQ--TVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQ

PSKFIDDFVNGQLRYTGMLE-TTRIRREGYSFRPTFAEFMERFGILAYGPSARV------EASSQTCSKVLAAS---GV--KGWLVGKTK
| .| .. |  |||. |.|| . ||.|.|...|.|..||..|. ||.    ...      ... | | |.| .    .   . . .||||
PWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPKTWWSWIWPEWNGDTKQGCEKILQHLSWGNMDKEEYQFGKTK
Myosin_head 32425.AA Myosin_head 106-184 37 3.1e-27 93.65 Pfam 1-80 (765) Show / Hide 
Range on Protein: 106-184
Range on HMM: 1-80/765
Sequence Identity: 37% (30 aa)

VDDLASLANLDDSILLEELKTRYF-ANKIYTYVGDILVAINPFQDLPLYTKQIKDQYHDIPKSAAAPHVYAIADQAYHSM
|.|.. | .| .  .|. ||.||. . .||||.|......||.. ||.||. . . |.   .. ..||..|||| || .|
VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLPIYTQDMIQEYRGKHRYEMPPHIFAIADEAYRHM
SH2 32425.AA SH2 825-908 39 5.8e-26 93.49 SMART 1-87 (87) Show / Hide 
Range on Protein: 825-908
Range on HMM: 1-87/87
Sequence Identity: 39% (35 aa)

MPWFHGLISRREAEELLRP--RYIGCFLVRVSEN-RFGYTLSYRVSDRCRHYMVEQNTQGQYALVG-VSKIADSLNELIEWFQRNPIN
.||.|| ||| |||.||.      |.|||| ||. . .|.||.|. ....|| ...|  |.| . .  ..  .|| ||....|.||. 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 32425.AA SH2 827-902 42 4.4e-23 69.59 Pfam 1-81 (81) Show / Hide 
Range on Protein: 827-902
Range on HMM: 1-81/81
Sequence Identity: 42% (35 aa)

WFHGLISRREAEELLRP--RYIGCFLVRVSENRF-GYTLSYRVSD---RCRHYMVEQNTQGQYALVGVSKIADSLNELIEWF
|.|| ||| |||.||.      | |||| ||.   .|||| |  .   | .|| . .. .|.| . |  |  .||.||.| .
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK-FCSLQELVEHY