N19

Species: M.brevicollis
Alias: N19
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: SH2-PDZ

Sequence

Name Sequence Type Origin Length Description Download
N19.AA Protein None 524 None Fasta, JSON

Protein domain

Protein domains of N19.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 N19.AA SH2 5-91 26 1.3e-09 39.15 SMART 1-87 (87) Show / Hide
Range on Protein: 5-91
Range on HMM: 1-87/87
Sequence Identity: 26% (24 aa)

PSWLHGKLTREKTDELVMRNGGEDGTFLVYEKDDSSPQERKFVLCVTYKGKPTHHLIKKSG-ENWTLNG---KVFGDPTSLVKVRGCEPRI
  | ||...||. ..| ...|..||.||| . .    . ...||.| .|||  | .|....   . . .   . | .   ||      |  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 N19.AA SH2 7-33 51 2e-06 20.54 Pfam 1-27 (81) Show / Hide
Range on Protein: 7-33
Range on HMM: 1-27/81
Sequence Identity: 51% (14 aa)

WLHGKLTREKTDELVMRNGGEDGTFLV
| |||..|..  .| |  |..||||||
WYHGKISRQEAERLLMNPGNPDGTFLV

PDZ N19.AA PDZ 460-523 19 0.000702 17.56 SMART 1-80 (80) Show / Hide
Range on Protein: 460-523
Range on HMM: 1-80/80
Sequence Identity: 19% (16 aa)

QSWGMEINSRSPPLVKSVAPHGVAASAG------LQPGDCIAYINN-QDMTRCDISYVLPTMRSA-----------STYHLV
...|  | .  . ...|| | |.|. ||      |.||| |  .|. |... ..   ..  ....              .  
GGLGFSIVG--GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG

PDZ N19.AA PDZ 450-503 25 0.000881 15.5 Pfam 1-62 (86) Show / Hide
Range on Protein: 450-503
Range on HMM: 1-62/86
Sequence Identity: 25% (16 aa)

RLTLTRDNVTQSWGMEINSRSP------PLVKSVAPH-GVAASAG-LQPGDCIAYINNQDMT
 .|| ...  ...|. | . ..        ...| |  | |. .| ...|| |  ||.||..
QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIR