Gene 33646 (M.brevicollis)

33646

Species: M.brevicollis
Alias: 33646
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: SH2-R

Sequence

Name Sequence Type Origin Length Description Download
33646.AA Protein None 1552 None Fasta, JSON

Protein domain

Protein domains of 33646.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 33646.AA SH2 655-737 25 0.000331 10.51 SMART 1-87 (87) Show / Hide 
Range on Protein: 655-737
Range on HMM: 1-87/87
Sequence Identity: 25% (22 aa)

APYYLQNQTASHVQEQLEG--LPDGTFYIYD-DGKGHNFYLCYRHAEQTKTATISATA-EGVFIST-STEKFGSLIELVCYYSNANAD
 |.|  | . . ... | .   |||.| . | . .   . |..|. .. |   |  ..  ...| . . .|| || ||| .|.     
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 33646.AA SH2 705-731 39 0.105037 6.83 Pfam 55-81 (81) Show / Hide 
Range on Protein: 705-731
Range on HMM: 55-81/81
Sequence Identity: 39% (11 aa)

ISATAEG-VFISTSTEKFGSLIELVCYY
|  |..| ..|.. .  |.|| ||| .|
IQRTDNGGYYITGRHK-FCSLQELVEHY
Sam7 33646.AA sam7 827-888 31 6.9e-18 61.43 In-house 1-70 (70) Show / Hide 
Range on Protein: 827-888
Range on HMM: 1-70/70
Sequence Identity: 31% (22 aa)

LTVAHIVTWLKNEGM---GEYAGNFKKQKV-----DGVRLLALTEDDLARLGVSFPQHRQQIMRAIDKLR
 |. ... ||.  ||   ..|. ||.....     ||  |. .||.||...|.. | ||. |...|...|
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM 33646.AA SAM 824-890 36 2.3e-17 64.94 SMART 1-67 (67) Show / Hide 
Range on Protein: 824-890
Range on HMM: 1-67/67
Sequence Identity: 36% (25 aa)

GAQLTVAHIVTWLKNEGMGEYAGNFKKQKVDGVRLLALT-EDDLARLGVSFPQHRQQIMRAIDKLRRR
    |.  .  ||.  ||..|. ||.|...||  ||.|| ..|| ..|.. |.||. |..|| |.. .
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 33646.AA SAM_2 832-888 30 9e-15 53.54 Pfam 9-71 (71) Show / Hide 
Range on Protein: 832-888
Range on HMM: 9-71/71
Sequence Identity: 30% (19 aa)

IVTWLKNEGM-GEYAGNFKKQKVDG-VRL-LALTEDDL--A-RLGVSFPQHRQQIMRAIDKLR
.  ||.. || ..|. ||......|   | . .|.|||  . |.|.. ..||..|...|....
VCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM_1 33646.AA SAM_1 825-888 31 1.6e-14 54.42 Pfam 1-66 (66) Show / Hide 
Range on Protein: 825-888
Range on HMM: 1-66/66
Sequence Identity: 31% (21 aa)

AQLTVAHIVTWLKNEGMGEYAGNF-KKQKVDGVRLLALTEDDLAR-LGVSFPQHRQQIMRAIDKLR
 . ..  .  ||.  ||..|. .| .....|.  || .|..|| . .||  | ||. ||..| .|.
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHRKKIMYSIQMLK
SH2 33646.AA SH2 1307-1389 21 5.7e-05 18.71 SMART 1-87 (87) Show / Hide 
Range on Protein: 1307-1389
Range on HMM: 1-87/87
Sequence Identity: 21% (19 aa)

QAWFFKDLSKTTCEDFLQY--EQTGSFVVHSSESAPGSYNLAYLN-HTVNSALLEATG-SGFRLQG-TGENWPSLQAAIQSLVAVFHP
| |.. ..|.  .|. |.    . |.|.|  ||| ||.| | .     |   ... .. ....... ...  |||   ..       .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 33646.AA SH2 1309-1343 35 5.7e-05 16.41 Pfam 1-37 (81) Show / Hide 
Range on Protein: 1309-1343
Range on HMM: 1-37/81
Sequence Identity: 35% (13 aa)

WFFKDLSKTTCEDFLQY--EQTGSFVVHSSESAPGSY
|.....|.   |. |.    . |.|.|  ||| ||.|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDY
SH2 33646.AA SH2 1461-1543 23 5.3e-11 43.8 SMART 1-87 (87) Show / Hide 
Range on Protein: 1461-1543
Range on HMM: 1-87/87
Sequence Identity: 23% (21 aa)

MDWDWRSRTRQEALAYLRG--KPPGTFIIRASD--KSFAALSMIIGDGSDYHMHIEQSA-AGVNFKK-SRDVFDNLLSLLEHYAQPSQN
. | .   .|.|| . |..  .|.|.|..| |.  . . .||.  . |  .| .|....  .. .   .|  |..|  |..|| .... 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 33646.AA SH2 1463-1537 29 8.3e-08 24.75 Pfam 1-81 (81) Show / Hide 
Range on Protein: 1463-1537
Range on HMM: 1-81/81
Sequence Identity: 29% (24 aa)

WDWRSRTRQEALAYLRG--KPPGTFIIRASDKSFA---ALSMIIGD--GSDYHMHIEQSAAGVNFKKSRDVFDNLLSLLEHY
| ... .||||  .|.   .|.|||..| |.       .||   ..   . .| .| . . |  .   |. |..|  | |||
WYHGKISRQEAERLLMNPGNPDGTFLVRESES-TPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY