N13

Species: M.brevicollis
Alias: N13
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: SH2-R-Cad

Sequence

Name Sequence Type Origin Length Description Download
N13.AA Protein None 1641 None Fasta, JSON

Protein domain

Protein domains of N13.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
VWD N13.AA VWD 1-12 91 0.198933 6.58 Pfam 5-16 (163) Show / Hide
Range on Protein: 1-12
Range on HMM: 5-16/163
Sequence Identity: 91% (11 aa)

GDPHYTTFDGKY
||||||||||.|
GDPHYTTFDGRY

VWD N13.AA VWD 129-147 57 0.002708 13.01 Pfam 138-156 (163) Show / Hide
Range on Protein: 129-147
Range on HMM: 138-156/163
Sequence Identity: 57% (11 aa)

YQSNTVGICGNFNGNSGDD
||  | |.|||.||.. ||
YQNQTCGLCGNYNGEPRDD

EGF_2 N13.AA EGF_2 333-359 40 1e-07 27.63 Pfam 1-29 (29) Show / Hide
Range on Protein: 333-359
Range on HMM: 1-29/29
Sequence Identity: 40% (13 aa)

CPNSCSG-NGACN---NAKCVCDSG-FSGRDC
|   |.| .| ||     ||.||.| ..| .|
C---CNGHHGTCNNQGCGKCQCDDGWWQGDHC

EGF N13.AA EGF 333-358 22 0.002017 14.5 Pfam 1-36 (36) Show / Hide
Range on Protein: 333-358
Range on HMM: 1-36/36
Sequence Identity: 22% (8 aa)

CPN---SCSGNGACNNA----KCVCDSG---FSGRD
|.     |...| |..     .| |  |   ..|..
CNPNNNPCHHHGTCVDTPGGYTCQCPPGYLGYTGKR

TIG N13.AA TIG 367-480 16 0.003302 13.22 Pfam 1-82 (82) Show / Hide
Range on Protein: 367-480
Range on HMM: 1-82/82
Sequence Identity: 16% (19 aa)

PVITSLSATTCNI-KAAASC-ASDISVFGSNFWNAENLTCRYKVIASPAVASDSVLMVGESASRSAFFLGSSEVICQLPDRAVFVPAGLQGDLVTIEISV
|.|||.|       . . ..  . |.. |.||                  . |.  ..| ..     .  |....|..|  .       .|  ... . |
PTITSIS-----PNTTGPPSGGTTITITGQNF---------------GNDS-DTKCYFGGTPCTVI-WWSSTQIVCTTPPHT-------PG-THNVSV-V

STTDSIVSEASLPFTF
.      | ....||.
NG---QWSSNPTTFTY

EGF N13.AA EGF 494-508 46 0.169688 8.07 Pfam 1-15 (36) Show / Hide
Range on Protein: 494-508
Range on HMM: 1-15/36
Sequence Identity: 46% (7 aa)

CAPNPDSCSIDGVCV
|.||.. |. .| ||
CNPNNNPCHHHGTCV

EGF_2 N13.AA EGF_2 494-523 19 38.724466 0.79 Pfam 1-18 (29) Show / Hide
Range on Protein: 494-523
Range on HMM: 1-18/29
Sequence Identity: 19% (6 aa)

CAPNPDSCSI-DGVCVLEGTHEASNVCRVCV
|      |.  .|.|.         .|..|.
C------CNGHHGTCNNQ-------GCGKCQ

Cadherin N13.AA Cadherin 654-737 36 2.7e-17 62.94 Pfam 1-94 (102) Show / Hide
Range on Protein: 654-737
Range on HMM: 1-94/102
Sequence Identity: 36% (34 aa)

YTFNVTEDTPVGTVVGTIMAYDPD-EAGSLQYEWYSQVAGE---AGVLLIDESTGV---ITVGKALDYERV-SSYLLLVSVRDG--GLQHMASV
|.| | |..|||| |.|. |.||| . |  ..  || . |.   ..   ||. ||.   ||. | ||.|   . | | |...|.  | . . |.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSST

CA N13.AA CA 671-749 25 1.8e-13 52.01 SMART 1-121 (121) Show / Hide
Range on Protein: 671-749
Range on HMM: 1-121/121
Sequence Identity: 25% (32 aa)

IMAYDPDEA--GSLQY------EWYSQVAGEAGVLLIDESTG-----------VITVGKALDYERV---------SSYLLLVSVRDGG------------
. | ||||   |.           || |        ||..||           .||. |.||.|           ..| | | ..|||            
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------LQHMASVHVFVGDVNEAPT
      |.  ..|...| |||. | 
FQQNPPLSSTCTVTIHVLDVNDNPP

CA N13.AA CA 771-850 22 1e-05 26.22 SMART 1-121 (121) Show / Hide
Range on Protein: 771-850
Range on HMM: 1-121/121
Sequence Identity: 22% (28 aa)

LTAQDQDAG----DSH-------TFSVGGTDAAYFQVVGAT-------------LQTAQELDYEALHAAGK----NPLAITITATDAGG-----------
.|| | |.|     ..       |.|. |    .|..   |             . |...||.|. .   .        .|..|||.||           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------LTLTKAFDITVQDVNEAPY
      |. |  . |.|.|||. | 
FQQNPPLSSTCTVTIHVLDVNDNPP

Cadherin N13.AA Cadherin 754-843 25 0.003004 14.01 Pfam 1-102 (102) Show / Hide
Range on Protein: 754-843
Range on HMM: 1-102/102
Sequence Identity: 25% (27 aa)

SNNVVAENQPVGTVVANLTAQDQD----AGDSHTFSVGGTD---AAYFQVVG--AT---LQTAQELDYEALHAAGKNPLAITITATDA-G---GLTLTKA
 .  | ||.|||| |...||.| |    .  . ..|  |..   .  | .     .   . |...||.|.      .   .|. |||. .   ... |  
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQ----NGQYHLTVMATDHDDGGPPRSSTTT

FDITVQ
  |||.
VTITVC

CA N13.AA CA 871-949 22 3.2e-08 34.55 SMART 1-121 (121) Show / Hide
Range on Protein: 871-949
Range on HMM: 1-121/121
Sequence Identity: 22% (28 aa)

VTVQDQDAG-----QT------VTCTIVQESTPTFELLDMK-------------LYALPGQQLDHETN---------PSIELTIGCADDGTPM-------
||. | |.|             ||..||.     |.. .               ....  ..||.|.          |. .||.   | |.|        
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTT--KPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPT

--------KYATATFTITVLDAFDMPG
        . .|.|.||.|||  | | 
RKFQQNPPLSSTCTVTIHVLDVNDNPP

Cadherin N13.AA Cadherin 907-942 35 9.2e-05 19.28 Pfam 64-102 (102) Show / Hide
Range on Protein: 907-942
Range on HMM: 64-102/102
Sequence Identity: 35% (14 aa)

QQLDHETN-PSIELTIGCADD--GTPMKYATATFTITVL
..|| |.  .  .||. . |   |.| ...|.| ||||.
KPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTITVC

Cadherin N13.AA Cadherin 955-978 45 0.010976 12.05 Pfam 1-24 (102) Show / Hide
Range on Protein: 955-978
Range on HMM: 1-24/102
Sequence Identity: 45% (11 aa)

QPETIYENATIGTVVGTVVAVDQD
.. .. ||| .|| |.|| |.| |
YHFSVCENAPVGTFVMTVTATDPD

Cadherin N13.AA Cadherin 1072-1167 25 2.5e-09 35.17 Pfam 1-102 (102) Show / Hide
Range on Protein: 1072-1167
Range on HMM: 1-102/102
Sequence Identity: 25% (27 aa)

TGGTVEENLALGGVIGTISAQDPD-----QGQTHTFSLASH---QDRFTLSNDASGMYATIRLSQTAASPLNYDSE-PSIELSIVVLDS--GNPPRSITT
  ..|.|| . |  ..|. |.|||      .. . . |  .    . |..  |   .   .... |.   |.. .  .  .|.... |.  | |||| ||
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDN---GIITTTKP--LDREQQNGQYHLTVMATDHDDGGPPRSSTT

SITITVE
..||||.
TVTITVC

CA N13.AA CA 1089-1170 19 2.9e-05 23.27 SMART 1-121 (121) Show / Hide
Range on Protein: 1089-1170
Range on HMM: 1-121/121
Sequence Identity: 19% (25 aa)

ISAQDPDQG-----QT------HTFSLASHQDRFTLSNDASGMYA-----TIRLSQTAASPLNYDSE---------PSIELSIVVLDSGNPP--------
..| |||.|              |.|. .    |..  .    |.      | .. |   ||....          |. .| ... |.|.||        
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTT--KPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------RSITTSITITVEN----QP
       .| |...||.|.      |
KFQQNPPLSSTCTVTIHVLDVNDNPP

CA N13.AA CA 1309-1393 17 0.001613 5.39 SMART 1-121 (121) Show / Hide
Range on Protein: 1309-1393
Range on HMM: 1-121/121
Sequence Identity: 17% (22 aa)

LVASDPEG------GD------VTFSMASSSSQVMQTYFQVSTTIRG--------TFELSVIQNLAMANIAS-------GDYNLDVQAEDATG-------
..|.||        |.      ||.|. .        .|.. ..             .... . |   ..           |.| ||| |. |       
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSH

----------HSSTQRVVVTLTDGTTDPS
          .|||  |.....|    | 
PTRKFQQNPPLSSTCTVTIHVLDVNDNPP

CA N13.AA CA 1197-1282 15 0.004293 1.04 SMART 1-121 (121) Show / Hide
Range on Protein: 1197-1282
Range on HMM: 1-121/121
Sequence Identity: 15% (20 aa)

VGKFVLQGN---DNQA------ATYSV-RFADNRRRAADAFSIQGLN-------------LVLSSPLDAEEV---------QTQSLNVVAVETIGSEVN-
|    .      .|         |||. .           |||   .             .... ||| ||          .. .|.|.|.   |   . 
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPD

------------YYAAQQLTINIQNEDEAPV
              .  ..||... ... | 
SHPTRKFQQNPPLSSTCTVTIHVLDVNDNPP

Cadherin N13.AA Cadherin 1360-1386 35 0.459721 6.4 Pfam 72-102 (102) Show / Hide
Range on Protein: 1360-1386
Range on HMM: 72-102/102
Sequence Identity: 35% (11 aa)

SGDYNLDVQAEDA----TGHSSTQRVVVTLT
.| |.| | | |.    .. ||| .|..|..
NGQYHLTVMATDHDDGGPPRSSTTTVTITVC

TIG N13.AA TIG 1283-1337 18 2.740044 3.34 Pfam 37-82 (82) Show / Hide
Range on Protein: 1283-1337
Range on HMM: 37-82/82
Sequence Identity: 18% (10 aa)

FGSSSYTATVDTTTVSAGDLVVLSPALVASDPEGGDVTFSMASSSSQVMQTYFQV
||..  | .    ..|.  .|. .|...   |. ..|.. . . .. .. | |..
FGGTPCTVI----WWSSTQIVCTTPPHT---PGTHNVSV-VNG-QWSSNPTTFTY

Cadherin N13.AA Cadherin 1183-1275 20 10.616814 1.65 Pfam 1-102 (102) Show / Hide
Range on Protein: 1183-1275
Range on HMM: 1-102/102
Sequence Identity: 20% (21 aa)

NSLTVSESTSVGTVVGKFVLQGND-----NQAATYSVRFADNRRRAADAFSIQGLNLV-----LSSPLDAEEV-QTQSLNVVAVETIGSEVNYYAAQQLT
 . .|.| ..||| |. .  .  |     |. ..||    . .   .. |.|.  . .     .  ||| |.  .. .|.|.|.   . . . ..  ..|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPD--PGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVT

INIQ
|...
ITVC

SH2 N13.AA SH2 1479-1569 32 4.9e-14 53.86 SMART 1-87 (87) Show / Hide
Range on Protein: 1479-1569
Range on HMM: 1-87/87
Sequence Identity: 32% (30 aa)

YEWYQPEMTRQDCSSELAT--AAPGTFLVRDSKATPGWHILGVKTENDVLHEKIRATDDGMYQLLPSSGPAHEQPRFGDLPSLINHYGSRQSG
..||   ..|... . | .    .|.||||||  .||  .| |.... | | .|| .|||.| .  .       ..| .|  |.|||     |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET-----WRRKFPSL-ELVNHYQHNPLG

SH2 N13.AA SH2 1481-1563 32 7.2e-11 33.73 Pfam 1-81 (81) Show / Hide
Range on Protein: 1481-1563
Range on HMM: 1-81/81
Sequence Identity: 32% (29 aa)

WYQPEMTRQDCSSELAT--AAPGTFLVRDSKATPGWHILGVKTEN---DVLHEKIRATDDGMYQLLPSSGPAHEQPRFGDLPSLINHY
|| . ..||.    |      .||||||.|  |||   | |....    | | .|. ||.| | .        . ..|..|. |..||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYIT-------GRHKFCSLQELVEHY