Gene 27493 (M.brevicollis)

27493

Species: M.brevicollis
Alias: 27493
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Shc

Sequence

Name Sequence Type Origin Length Description Download
27493.AA Protein None 587 None Fasta, JSON

Protein domain

Protein domains of 27493.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PTB 27493.AA PTB 208-333 13 1.6e-07 32.22 SMART 1-156 (156) Show / Hide 
Range on Protein: 208-333
Range on HMM: 1-156/156
Sequence Identity: 13% (21 aa)

DVRIPCH--YVGTFEVGSGE------VDRGMVKKGVEVMDEYAANARPTDFLMTLKGIRIVDKTNQQVAMAHALQRISMSSIV------------SEKRL
..   .   |.|..|| .          . ....  . ...     .. ..  . .|....|. ..||.. |...||| ..              . .|.
PWGCCFNVWYLGCVEVPHHRNSMAPGKGMQVCQECMRKIRQHWKHWQKMHLHISVDGVKLIDPQTKQVIHHHPIHRISFCAHDPYRWNTGGHHCCDDDRC

FGLVAKNPGTK-------DKYCHVFKMARSQ---HTETAQALLSKAFKLAFAKNRS
||.....|..           ||||. . ..     .|.... ....... .....
FGYICRHPNDRGSHRMTYWFRCHVFWCEDPHAEDIAQTIGQAFQVCYQQCQKQRCQ
PID 27493.AA PID 253-306 19 0.000259 16.93 Pfam 64-125 (153) Show / Hide 
Range on Protein: 253-306
Range on HMM: 64-125/153
Sequence Identity: 19% (12 aa)

TLKGIRIVDKTN---QQVAMAHALQRISMSSI---VS-EKRLFGL-VAKNPGTKDKYCHVFK
. .|....|. .   |.. . |....||  .    .   .| |.. ... ...   .||||.
STDGVKWIDEKTEAEQECMHDHPMRNISFCADGGDPHVDMRYFAYDICRDGPCQRFACHVFW
SH2 27493.AA SH2 455-541 32 3.2e-19 71.08 SMART 1-87 (87) Show / Hide 
Range on Protein: 455-541
Range on HMM: 1-87/87
Sequence Identity: 32% (29 aa)

APWYQAGLPREIAVELLAM--SEDGAFIVRDSQSQKGCYALTMKAHGEIKNFIIKAIP-EGYIIGAAADGERPYASLAELILAHAERRGV
 |||   ..|| |..||     .||.|.||||.|..|.|.|... .|..|...|.  .  .| |.    ..|.. || ||.  .   ...
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET--WRRKFPSL-ELVNHYQHNPLG
SH2 27493.AA SH2 457-535 31 2.2e-18 55.79 Pfam 1-81 (81) Show / Hide 
Range on Protein: 457-535
Range on HMM: 1-81/81
Sequence Identity: 31% (27 aa)

WYQAGLPREIAVELLAM--SEDGAFIVRDSQSQKGCYALTMKAHG---EIKNFIIKAIPEG-YIIGAAADGERPYASLAELILAH
||   ..|. | .||     .||.|.||.|.|..|.|.|. .  |   ..| ..|.  ..| | |.    |.. ..||.||.  .
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYIT----GRHKFCSLQELVEHY