Gene 27082 (M.brevicollis)

27082

Species: M.brevicollis
Alias: 27082
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: SHIP2

Sequence

Name Sequence Type Origin Length Description Download
27082.AA Protein None 1009 None Fasta, JSON

Protein domain

Protein domains of 27082.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 27082.AA SH2 12-97 34 2e-16 61.79 SMART 1-87 (87) Show / Hide 
Range on Protein: 12-97
Range on HMM: 1-87/87
Sequence Identity: 34% (30 aa)

EAWHYTNMSRSVAETMLTRR-RAKGTFLVRDSERVQGASVLSVFQDDLVHHYRLTIREDNSVVVDG-VDAVYPSLRAMIHALQTENIL
. | . |.||. || .| ..    |.|||||||.  |. ||||. .. |.|||.   .|.....|.  .  .|||  ...  |.  . 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 27082.AA SH2 14-91 31 3e-15 46.58 Pfam 1-81 (81) Show / Hide 
Range on Protein: 14-91
Range on HMM: 1-81/81
Sequence Identity: 31% (26 aa)

WHYTNMSRSVAETMLTR-RRAKGTFLVRDSERVQGASVLSVFQDD---LVHHYRLTIREDNSVVVDGVDAVYPSLRAMIHAL
| . ..||. || .|   .   ||||||.||. .|  .|||. |.    |.|||    ..  . . | .  ..||  ...  
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK-FCSLQELVEHY
IPPc 27082.AA IPPc 422-726 23 6.6e-70 239.47 SMART 1-435 (435) Show / Hide 
Range on Protein: 422-726
Range on HMM: 1-435/435
Sequence Identity: 23% (101 aa)

SKLSIWIGTFNMGDVA------APNDLSSWFACQG-QGRALPSNSEHDILAIGCQEA-------------------------------------------
 .... .||.|.. .        .||...|... . |.     .  .|| .||.||                                            
QDWKVCVGTWNVNGQFFRMKADPKNDVTNWLFQMIDQEFECKQDHKPDIYVIGFQEMGWKNYENCMQHVWDFINNCKQNAMKKYIWQRSYHLENGHIIEH

-GMAEKDWLALVRQHIG-----AGYQQLAFAK-LLQIRLVVFVRDQHMNKVSHLQQSVVATGLANKLGNKGGVGIAFFVNQT----SFCFINSHLAAGSE
    |. |. ...  .        |. |.    .. | . |||..|| ....| . ..| ||.... ||||.|.. . ...|    .|||.|.|||.. |
NTTKERFWSNHIEWWMMQYSRDDQYNCLWCERYMWGIFVCVFVKNQHAWYIKHVHTFTVKTGMWGMWGNKGAVAVRWQMHDTENWWWFCFVNCHLAHHQE

---KLLKRNTNALDI-FSKLQLGQKHLSGFDI---------LNQFHHVFFFGDLNYRINLPV---------------------------------NMVID
   .  .|| .  ||  ..| . .  ......         .  . |||.|||.||||..|                                  . | .
NLNNWEQRNQDYKDIRCRALCFPERKMTHQHNRFVEVPKMCIMDHDHVFWFGDFNYRIDMPNYYNVMCTDQEMMTVRADDTQAIFRNSQNDRHVMEDVRR

DAKRQQ---YTRLCQYDQLLMQRGSQKMFFGFEEGPIEFPPSYRYKRGTRDVYEYEKQKASGIKINVPSYTDRIMWRS------FPNLYIKQTS------
  ...    . .| . |||  |.  .| | .|.|.|| |||.|.|..   | ....... .. | .||. .||| |||       ||| .. .|      
FITQKENEHFDWLWEWDQLNRQMEAGKVFQDFHEMPIKFPPTYKYDP---DHQCHTETYDTSEKCRVPAWCDRILWRSKWQFYNYPNLIQECESYCPVTK

-----------YGATTDIMTSDHSPVFATFDIQVTDQH
           | .. .|.|||| ||||.|.| |..  
KIYQWEKVYHYYHCCMEICTSDHKPVFAMFRIKVKMVD
Exo_endo_phos 27082.AA Exo_endo_phos 426-718 18 1.3e-30 110.7 Pfam 1-200 (200) Show / Hide 
Range on Protein: 426-718
Range on HMM: 1-200/200
Sequence Identity: 18% (57 aa)

IWIGTFNMGDVAAPNDLSSWFACQGQGRALPSNSEHDILAIGCQEAGMAEKDWLALVRQHIGAGYQQLAFAKLLQIRLVVFVRDQHMNKVSHLQQSVVAT
. |.|.|..   . . .          . |     ||.  |. ||  | . . . .   . . .                                   |
MKIMTWNVNGLRY-T-K----------WLLEWLH-HDPDIICLQETWMSP-Q-F-HH-HY-YYW----------------------------------YT

GLANKLGNKGGVGIAFFVN-----------------QTSFCFINSHLAAGSEKLLKRNTNALDIFSKLQLGQKHLSGFDILNQFHHVFFFGDLNYRINLP
.  .  ||.|||.| . ..                  . |||.|.||.... ..  ||  . ||. .||             .  .....||.|||.. .
HFYH-GGNYGGVAIFWKWPIFHVIQHHDFIRRIKTNGR-FCFVNTHLPWHG-WFDQRNQQYWDIYDFLQF------------RHDPWIWCGDFNYRHDEW

VNMVIDDAKRQQYTRLCQYDQLLMQRGSQKMFFGFEEGPIEFPPSYRYKRGTRDVYEYEKQKASGIKINVPSYTDRIMWRSFPNLYIKQTSYGATTDIMT
.  ..   ...                         |.||.||....|.|.|            . | |.|...|.| |..    .. .  .  .  .| 
DY-NWK-RRKMWW-----------------------EHPITFPYTWWYYRNT------------SRKHNTPWWIDYIWWSG-WM-RV-WC-IHDE--HMP

SDHSPVFATF
||| ||.|||
SDHCPVYATF
Sam7 27082.AA sam7 969-1003 25 0.000426 12.53 In-house 31-70 (70) Show / Hide 
Range on Protein: 969-1003
Range on HMM: 31-70/70
Sequence Identity: 25% (10 aa)

D----DLEFFSDLAEEDLQDIGVSAP-DIQIIMTAIAKRN
|    |.. .  . ||||...|.. |   . |...| .  
DDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR