38850

Species: M.brevicollis
Alias: 38850
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: STAT

Sequence

Name Sequence Type Origin Length Description Download
38850.AA Protein None 638 None Fasta, JSON

Protein domain

Protein domains of 38850.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
STAT_bind 38850.AA STAT_bind 49-296 28 3.9e-51 153.74 Pfam 6-269 (269) Show / Hide
Range on Protein: 49-296
Range on HMM: 6-269/269
Sequence Identity: 28% (78 aa)

QP--------PSVLKTQTKFTTTCAFLISD-ALALFLDPPTVTVSVINESQAIDVNERNQAGLSGLQRQDAVGESG-GLQNNQKVLGSASADGVLQAAFK
||        | ||||||.||..  .|.    |   . ||.|    ..|.||.    ||      ...  . |..    .|. ...    | ... . |.
QPCMPMHPQRPQVLKTQTQFTVKVRWLVKLQELNYHMKPPVVIDKNVSEKQAQRGVVRNTQ----FRKFNICGTNTGKIMNMECSMNYSLAWEFCHLQFR

TLSLKKIRRSD-KGESDVSVTDEKFSLCYSLTLTLSQGDVVLNLHKLSAPIVVVVHGNQLPSAEATIMWDRAFALPAR--TGFQVDAVVPWNRVCHALSA
 ...||| | . ||    |||.||...| . ..... .. .. |  .| |.|| .|.||.|.| |.|.|. .|. . |    | |   |.||..| .|. 
NMRCKKIKRCNRKGC--ESVTEEKHCICFETQFCHQGNKLKIQLWTHSLPVVVISHMNQMPNAWASILWYNMFTEMPRNLVFFMVPPRVTWNQLCEVLNW

YHKHQVG--VSLNSDHFVFLSQ-LAGQSPD------NMVYPWPLLAKEPLAGRTFSLWEWFYNICELSRK
  .  ||   .||.|....| . | .|.         .  .|    ||...|. |. |.|| .| .| .|
QFSSCVGTNRGLNIDQLHMLAEKLFNQNSSHMEDYQHCSITWSQFCKENMPGWNFTFWQWFDAIMDLIKK

SH2 38850.AA SH2 306-353 34 2.4e-07 23.38 Pfam 1-49 (81) Show / Hide
Range on Protein: 306-353
Range on HMM: 1-49/81
Sequence Identity: 34% (17 aa)

LIHGFISKDRSEELMMD--ASPGTFVLRFSASMLGGLSVTWITVDEDGDR
 .||.||.   |.| |     .|||..|.| |  |. .... . .. |||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP-GDR

SH2 38850.AA SH2 308-386 20 0.000542 8.22 SMART 5-87 (87) Show / Hide
Range on Protein: 308-386
Range on HMM: 5-87/87
Sequence Identity: 20% (19 aa)

HGFISKDRSEELMMD--ASPGTFVLRFSASMLGGLSVTWITVDEDGDRQPWQLKDFAIRNLPERILDLDD----------LTHLYPGRPKE
||.||..  |.| .     .|.|..|.| |. |...... .          . | . || ....   .|.          | . |   |  
HGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK--------GKVKHYRIRRNDDGKYYIDETWRRKFPSLELVNHYQHNPLG