8990

Species: M.brevicollis
Alias: 8990
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
8990.AA Protein None 472 None Fasta, JSON

Protein domain

Protein domains of 8990.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 8990.AA SH2 373-457 22 8.3e-08 33.18 SMART 1-87 (87) Show / Hide
Range on Protein: 373-457
Range on HMM: 1-87/87
Sequence Identity: 22% (20 aa)

PDWLFRELDWESSEFLLDG--EEPGTFLIRA--Q-DDALTLSLKRVDARIEHVPIMQSSATGLYYLTGLKRVSRSSVAHLVSYLVADHVR
  | .  ...|  | || .   ..|.||.|   .   ...||..    .. |  | ..   | ||.... |.. .|. .|| .      .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 8990.AA SH2 388-451 27 0.000958 12.82 Pfam 15-81 (81) Show / Hide
Range on Protein: 388-451
Range on HMM: 15-81/81
Sequence Identity: 27% (19 aa)

LLD-GEEPGTFLIRAQD---DALTLSLKRVD--ARIEHVPIMQSSATGLYYLTGLKRVSRSSVAHLVSYL
|.  | ..||||.|  .      |||... .   |..|  |..    |.|. .. |    .|...||.. 
LMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK---FCSLQELVEHY