12142

Species: M.brevicollis
Alias: 12142
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
12142.AA Protein None 382 None Fasta, JSON

Protein domain

Protein domains of 12142.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 12142.AA SH2 262-337 31 1.2e-16 50.68 Pfam 1-81 (81) Show / Hide
Range on Protein: 262-337
Range on HMM: 1-81/81
Sequence Identity: 31% (26 aa)

WYLGAVDRKEAEDLLRA--WPTGTFAVRKGRSSR---VITLKFPVAKDKVFFHVRITYEEPM-YRVADSECFRSIPELVAFY
|| | . |.|||.||..   | ||| ||. .|.    ......      .. | ||  .. . | ... ..|.|..||| .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP-GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

SH2 12142.AA SH2 260-343 29 4.2e-12 47.45 SMART 1-87 (87) Show / Hide
Range on Protein: 260-343
Range on HMM: 1-87/87
Sequence Identity: 29% (27 aa)

FQWYLGAVDRKEAEDLLRA--WPTGTFAVRKGRS---SRVITLKFPVAKDKVFFHVRITYEE-PMYRVAD--SECFRSIPELVAFYVDQPHR
 .|| | ..|.|||.||..   | |.| ||  .|   . |.....     . . | ||  ..  .|....  ...| |. |||..|   | .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK----GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG