28839

Species: M.brevicollis
Alias: 28839
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
28839.AA Protein None 663 None Fasta, JSON

Protein domain

Protein domains of 28839.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 28839.AA SH2 53-89 34 2.4e-05 17.51 Pfam 10-52 (81) Show / Hide
Range on Protein: 53-89
Range on HMM: 10-52/81
Sequence Identity: 34% (15 aa)

QADRYLAP--SPKGAFIIRKAS-QPGEFVLSVQAGV---RVCH
.| |.|     | |.|..|. . .||...|||  .    || |
EAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKH

SH2 28839.AA SH2 42-129 23 2.5e-05 22.47 SMART 1-87 (87) Show / Hide
Range on Protein: 42-129
Range on HMM: 1-87/87
Sequence Identity: 23% (22 aa)

EPWCKLRWGKIQADRYLAP--SPKGAFIIRKASQ-PGEFVLSVQAGVRVCHVLLKVICGEDERVLYNIYP-TPQWFESLFDLPFMFRNLHGT
.||.  .  . .|.. |     | |.|..|  .. ||..||||  . .|.| ...          | |   .. .|.|| .|   ..   . 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD----GKYYIDETWRRKFPSL-ELVNHYQHNPLG

PH 28839.AA PH 174-277 25 6e-19 70.96 Pfam 1-92 (92) Show / Hide
Range on Protein: 174-277
Range on HMM: 1-92/92
Sequence Identity: 25% (27 aa)

ILFRGYLTKQGRVRKTWKRRFFELSDDGHLRYFTVAGKDKEQGSLNLKKVRAVIPGAKCVVQWHPQANPNYCFGILACDR-ELFLFADTKDELQGWLQAI
.  .|.|.|.|  ||.||.|.| | . ..| |.   .  . .||..|.... ...            . ..|| |   || .....|.. .|.. |.|||
VIKEGWLHKKG-KRKSWKKRWFVLFN-NCLYYYKDDK-YRPKGSIPLSDCQVTKVPDN---------KRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAI

RQVVD
.... 
QSACR

PH 28839.AA PH 174-279 23 4.3e-18 67.35 SMART 1-82 (82) Show / Hide
Range on Protein: 174-279
Range on HMM: 1-82/82
Sequence Identity: 23% (25 aa)

ILFRGYLTKQGRVRKTWKRRFFELSDDGHLRYFTVAGKDKEQGSLNLKKVRAVIPGAKCVVQWHPQANPNYCFGILACDRELFLFADTKDELQGWLQAIR
.. .|.|.|..  . .||.|.| | . . | |.      | .||..|.... .                  || |   ||..........|.| |.|||.
VIKEGWLYKKS--K-RWKKRWFVLFN-DCLYYYKDK---KPKGSIPLSDCTVRE-P---------------CFEIHH-DRTYYFQCESEEEMQEWMQAIQ

QVVDEK
..... 
KAIHNN