33775

Species: M.brevicollis
Alias: 33775
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP
Subfamily: PTP-H1

Sequence

Name Sequence Type Origin Length Description Download
33775.AA Protein None 1998 None Fasta, JSON

Protein domain

Protein domains of 33775.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B41 33775.AA B41 24-202 23 7.6e-30 106.39 SMART 1-232 (232) Show / Hide
Range on Protein: 24-202
Range on HMM: 1-232/232
Sequence Identity: 23% (54 aa)

KRGDYVCVIRHLDNTEHSIYISGKATGDEVFRAFLREIEPL--PETDYFALYFPSK------------------S----RTVTLEFGVKFFVAD----PR
.. . .| .. .|.|  .. .  ..|| .....  |... .   |..||.|.. ..                  .     . || | |||.. |    | 
SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCG-ISPREHWYFGLWYEDPHEDRHWLDHWKTIMKQDVKWHKSEPWTLHFRVKFYPPDWHGFPN

QLQHDHTRF-LYYCQLKEDLASGRFVAP-HDVCWQLCAYIVQADIGDFNIS--------RCPEGYLSDMLLLPDQ---------------KPEDEDEIRN
|||.| ||. ..|.|...|. .||.  |  . |.||.|..||.. ||.. .        .. ..|.|.  .||.|               ..| .. |..
QLQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYKSYKRFLPKQWIDSIKQSFMHYQMHHKEWRKRIME

LHVQLEDMTADEAMLAFLELASQQL-LYGLDIH
.| ..  || .||.| .|....    .|| . .
WHKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF

FERM_M 33775.AA FERM_M 93-202 18 5e-23 80.32 Pfam 1-171 (171) Show / Hide
Range on Protein: 93-202
Range on HMM: 1-171/171
Sequence Identity: 18% (31 aa)

DPRQ-LQHDHTRFLYYCQLKEDLASGRFVAPHDVCWQLCAYIVQADIG-DFN-ISRCPEGYLSDML--------------------LLP-----------
||   .|.. || ..|.|.|.|.  ||. .. . ...| ||..|...| |.|  .  ...|. . .                    ..|           
DPNRDIQDEVTRHQFYLQAKWDILEGRYPCSEEEALMLAAYQCQIEFGSDYNPPQKHKSDYMEKEWWEQQEGMEVWLRCDNEQQERYWPAHCRLASKGRT

-------------------------DQKPED-EDEIRNLHVQLEDM-TADEAMLAFLELASQQLLYGLDIH
                         ..| .. |..|  .| ... | ...|||| .......   || . .
MADSSYSEVSIRINPHCYVSPWYCKKMKQKQWEQRILEQHKNHRGMCSPEEAMLQYIQICQRWPMYGVHFF

GuKc 33775.AA GuKc 697-872 21 2.8e-05 -16.26 SMART 1-203 (203) Show / Hide
Range on Protein: 697-872
Range on HMM: 1-203/203
Sequence Identity: 21% (44 aa)

APRPVVLLGA---GKANVEAALLERFPD--AYRLVRHDATDSH--GEAE----SYRFVD-LDTFIHQAMRDEYAEVVRYGSD-LYGLPYA-SLRTDEDGR
 .||.||.|.   ||  . ..|....||  ..  .    | ..  || .     | ||.  . .   . .... |   | .  .|| . .      | |.
HRRPIVLSGPSGVGKSTLKHMLMQEYPDYPKFEFSVPHTTRPPRPGEVNGCVVDYHFVSLKEEMEQMIKHNKFLEWGEYHGNLYYGTSKETVRQVHEQGK

HPVIPICDPLVITTLQKH----GVFPIVIFLD--CDTSRRARLV----MPHDSASRVHAEVQL-AAKVKSHF---HAYFSGQVFPANSLEDVA-EVVHEV
| .. |  |  .  |...       |||||.    .   . ||.    .  ... | ... .  | |   |    |..| ...   ..|||   .   |.
HCILDID-PQGVRQLRYARRYSYFYPIVIFIKPPSMEELEERLRQPCQRGTETEERIQKRLAHQAQKEMQHYPKCHHEFDYVI-VNDDLEDACYKELKEI

VSTVQ
. . |
MEQEQ

PDZ 33775.AA PDZ 1002-1078 22 2.5e-15 58.16 SMART 1-80 (80) Show / Hide
Range on Protein: 1002-1078
Range on HMM: 1-80/80
Sequence Identity: 22% (20 aa)

AGYGFGFREGSESWCQNLPVVTSITAGGAAHLDGR-----LQSEDVLVEVNG-KGLASKSYVEVLTMIRGHSG-----ALRMTVKRRC
.|.||  ..          ...|. .||.|. .||     |.  |...|||| . . .... ... |... .|      ...||.|. 
GGLGFSIVG--------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG

PDZ 33775.AA PDZ 994-1075 18 5.8e-14 50.39 Pfam 1-86 (86) Show / Hide
Range on Protein: 994-1075
Range on HMM: 1-86/86
Sequence Identity: 18% (16 aa)

SIRIPRTIAGYGFGFREGSESWCQ--NLPVVTSITAG-GAAHLDGRLQSEDVLVEVNGKGLASKSYVEVLTMIRGHSG-ALRMTVK
......   . |.||.  ......  .  ..... .| |||. .||..  |.....||. ... .  ..  .|.| .|  ...|..
QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ

PDZ 33775.AA PDZ 1088-1162 19 4.3e-16 60.72 SMART 1-80 (80) Show / Hide
Range on Protein: 1088-1162
Range on HMM: 1-80/80
Sequence Identity: 19% (17 aa)

GKYGMGIRGGADSKTPVLISRIAEGSAAADEPQ-----IQIGEEITHING-TDVTQLTHAEVLALIKSSPS-----SLNLVIHPRR
| .|  |.|      ...||.. .|..|.         ...| .|. .|| ..|. .||.......|...      .. |.. .. 
GGLGFSIVG------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG

PDZ 33775.AA PDZ 1080-1159 29 6.3e-16 57.14 Pfam 1-86 (86) Show / Hide
Range on Protein: 1080-1159
Range on HMM: 1-86/86
Sequence Identity: 29% (25 aa)

EVTLLARDGKYGMGIRGGADSK----TPVLISRIAEG-SAAADEPQIQIGEEITHINGTDVTQLTHAEVLALIKSSPS-SLNLVIH
.|||  .|.  |.|...   ..    ... ||.. .| .||.  . |..|  |. |||.|.. .||... ..||.|.. .. |.| 
QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ

PTPc 33775.AA PTPc 1746-1988 25 5.7e-71 243.0 SMART 1-308 (308) Show / Hide
Range on Protein: 1746-1988
Range on HMM: 1-308/308
Sequence Identity: 25% (81 aa)

AISAMRRGLVKSR------------DCSLALKPENA--VRNRYR-DILPYDDTRVKLDS--------SNNDYINANHLSFESNGTTFSYIASQASLGPFL
 ....   | . .            .|. | .|||.   .|||. ||..||.||||| .        ...||||||. ...  . ...||. |. |    
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPL----

GPKPETSEHFWQMVWEQQVRLICMLTTLVEG--------GRTKCHQYWPSAPGDTCQFGDFSIVLNKEAARK-GYILRDITVQRANA--------KGKRR
   |.| |.||.|||.|... | ||....|.        || |||||||.    ....|.... . .|   . .|..|...|.  .         . .| 
---PHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRT

LFQLQFTAWPDHGLPTSSAEMLTLVKEINNLKSRL-------------------VKP---------------------MPLLEKAKEVNIPAILSQLREQ
. ....|.||||| | |.  .| ....... .|..                     |                     . ..|.   |.|. |....|.|
VTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQ

RMNLVQTQDQYKFVCGTVMALSK
|...||| .||.|..  .. . |
RPGMVQTEEQYIFCYRCILEYIK

Y_phosphatase 33775.AA Y_phosphatase 1768-1938 35 2.5e-61 214.86 Pfam 1-172 (243) Show / Hide
Range on Protein: 1768-1938
Range on HMM: 1-172/243
Sequence Identity: 35% (65 aa)

NAVRNRYRDILPYDDTRVKLD----SSNNDYINANHLSFESN-GTTFSYIASQASLGPFLGPKPETSEHFWQMVWEQQVRLICMLTTLVEGGR-TK-CHQ
|  .|||.||..||.|||||       . ||||||.  .  . .  . ||. |       ||.|.| |.||.|||.|... | ||....|.||  | |||
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG--PYWNPKAYICTQ-------GPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQ

YWPS-APGDTCQFGDFSIVLNKEAARKGYILRDITVQRANA--KGKRRLFQLQFTAWPDHGLPTS-SAEMLTLVKEINNLKS
|||. . |.....|||.. . .|   ..|..|. .|.  ..  . .|.. ....|.||||| | | .  || ....... ..
YWPDNKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP

Y_phosphatase 33775.AA Y_phosphatase 1944-1985 30 2.1e-10 37.68 Pfam 202-243 (243) Show / Hide
Range on Protein: 1944-1985
Range on HMM: 202-243/243
Sequence Identity: 30% (13 aa)

MPLLEKAKEVNIPAILSQLREQRMNLVQTQDQYKFVCGTVMA
. ..|. ..|.|. |....|.||...||| .||.|.. ... 
CQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

PTPc_motif 33775.AA PTPc_motif 1905-1985 19 2.8e-08 34.76 SMART 1-92 (92) Show / Hide
Range on Protein: 1905-1985
Range on HMM: 1-92/92
Sequence Identity: 19% (20 aa)

RLFQLQFTAWPDH-----GLPTSSAEMLTLVKEINNLKSRLVKPM------------------PLLEKAKEVNIPAILSQLREQRMNLVQTQDQYKFVCG
 . ....|.||||     |.|.    .|........       |.                   ....   |.|  .. ..|.||...||| .||.|.. 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ---VDIFQTVKEMRKQRPGMVQTEEQYIFCYR

TVMA
 .. 
CILE