Gene 39070 (M.brevicollis)
39070
Species: M.brevicollis
Alias: 39070
External Links:
Annotation:
Sequence
Protein domains of 39070.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| SH2 | 39070.AA | SH2 | 127-210 | 24 | 2.2e-08 | 35.08 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 127-210 Range on HMM: 1-87/87 Sequence Identity: 24% (22 aa) SSWYVGKISAAEAKIMLDT--EPCGAWLVRASAE-EHAYSLMVKDMRGDINNFLLTEEPKDGGICLGT---SRFDRVDDLIRKISKSGLK || |.|| .|| .| . | |. ||| | .|.| |.. | . .... .... |. .... .|. . .|.. .. | QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG |
|||||||||
| SH2 | 39070.AA | SH2 | 129-156 | 50 | 0.000523 | 13.59 | Pfam | 1-30 (81) | Show / Hide |
Range on Protein: 129-156 Range on HMM: 1-30/81 Sequence Identity: 50% (15 aa) WYVGKISAAEAKIMLDT--EPCGAWLVRAS || |||| .|| .| | |. ||| | WYHGKISRQEAERLLMNPGNPDGTFLVRES |
|||||||||
| SH2 | 39070.AA | SH2 | 415-499 | 22 | 0.000168 | 13.68 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 415-499 Range on HMM: 1-87/87 Sequence Identity: 22% (20 aa) CDWYAGRVSRQAAAAVILQSPNVRPGDFFFHQHPLEENVFYLTVNDHDRAAQYKIARNS-AGYVFGP---KTFLTLQRLLETARRTGLK . || |..||. | . .. ..||| . . . . |.| .... |.| || .|... ..| .| |.. ... | QPWYHGNISREEAEQLLKNP-GMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |
|||||||||
| SH2 | 39070.AA | SH2 | 417-442 | 38 | 0.056087 | 7.63 | Pfam | 1-25 (81) | Show / Hide |
Range on Protein: 417-442 Range on HMM: 1-25/81 Sequence Identity: 38% (10 aa) WYAGRVSRQAAAAVILQSPNVRPGDF || | .|| . | .|..| ..|.| WYHGKISR-QEAERLLMNPGNPDGTF |
|||||||||
| PTPc | 39070.AA | PTPc | 705-972 | 19 | 1.2e-46 | 162.19 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 705-972
Range on HMM: 1-308/308
Sequence Identity: 19% (69 aa)
DLRILPLDIQGYKELP-------RGETHESDLPDYARGPRLNRFR-DILPNPVTRVRLEPLEVD----HTLEYINANYVRDPSAPCDNKPALLGFGGRRA
.. ..| .. . . .. ....| . .. ||.. ||.... |||.| |.. . ||||||.. . .|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENRE-MDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY---------------WRP
KEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEG--------GKNKCSRYWPATIYAETKEELVYGPRDGKIHVRTMLVTKME-GYIKTNIQVLYQ
|.| ..|.|.. . ||||. . . ..|.| . ..|. |..|| .||| . ...|| .|.| .. ..|.. .|. ....| ..
KRYICTQGPLPHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-------PMTYG----HITVTCKSEEKCPDDYTMRTFEVTNT
G----------STRNLVHFWFTAWPDHGVP----------TRPDGSMQTQQ-------------------------------------MIEMLLDIRRTR
| || . |...|.||||||| . . ...... |..... ..
GCNCKYSMACSETRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN-
NELDRAMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAE
||.. || .|. |. ||| ||...|... ||..
----------VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
|
|||||||||
| Y_phosphatase | 39070.AA | Y_phosphatase | 735-927 | 27 | 1.1e-38 | 137.18 | Pfam | 1-172 (243) | Show / Hide |
Range on Protein: 735-927 Range on HMM: 1-172/243 Sequence Identity: 27% (54 aa) GPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDPSAPCDNKPALLGFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGK-N .. ||..||... |||.| |.. | ||||||.. ... |.| ..|.|.. . ||||. . . .||.| . ..|.|. . NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG--------------PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDE K-CSRYWPATIYAETKEELVYGPRDGKIHVRTMLVTKMEGYIKTNIQVLYQGS----TRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRN | |..||| .. ....|| ...| .. ......|. .. .| |. || . |...|.||||||| |.. |.... .| .. KTCHQYWPD---NKEGQPMTYG----DFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPES-----QPKSMLDFIRQVRKWQP |
|||||||||
| PTPc_motif | 39070.AA | PTPc_motif | 888-969 | 22 | 1.9e-07 | 31.97 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 888-969 Range on HMM: 1-92/92 Sequence Identity: 22% (24 aa) NLVHFWFTAWPDH-----GVPTRPDGSMQTQQM---------------------IEMLLDIRRTRNELDRAMGVKVDVLSIVADIREDRMAMVQHVVQYR . |...|.|||| |||. |. .. .. |.|... ||.. .| .|. |. ||| ||. TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRKPIVVHCSAGCGRTGTFCAIDMMMQQ--------------VDIFQTVKEMRKQRPGMVQTEEQYI YLYQAVVE ..|... | FCYRCILE |
|||||||||
| Y_phosphatase | 39070.AA | Y_phosphatase | 934-969 | 38 | 2.7e-07 | 26.75 | Pfam | 208-243 (243) | Show / Hide |
Range on Protein: 934-969 Range on HMM: 208-243/243 Sequence Identity: 38% (14 aa) GVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE . .||.. || .|. |. ||| ||...||...| EGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
|||||||||
| SH2 | 39070.AA | SH2 | 1085-1174 | 25 | 1.1e-14 | 56.04 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 1085-1174 Range on HMM: 1-87/87 Sequence Identity: 25% (24 aa) KPWFRSNFTRAQVEDLLSG--TPPGTFVVRPSSK-KDHFALSLQTVRHKIANMLIVPIAQPNGKFLYKLGASNDQSFSSVAELVEHYLEHGIP ||. | .|...|.|| . |.|.|.||.|.. . ...||. . |. . .| . . .. .. . .. .|.|. |||.|| . .. QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDD-GKYYIDET---WRRKFPSL-ELVNHYQHNPLG |
|||||||||
| SH2 | 39070.AA | SH2 | 1087-1124 | 34 | 5e-11 | 34.21 | Pfam | 1-41 (81) | Show / Hide |
Range on Protein: 1087-1124 Range on HMM: 1-41/81 Sequence Identity: 34% (14 aa) WFRSNFTRAQVEDLLSG--TPPGTFVVRPSS-KKDHFALSL |. . .|...|.|| |.|||.||.|. .. ...||. WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSV |
|||||||||
| SH2 | 39070.AA | SH2 | 1153-1168 | 50 | 0.002287 | 11.71 | Pfam | 66-81 (81) | Show / Hide |
Range on Protein: 1153-1168 Range on HMM: 66-81/81 Sequence Identity: 50% (8 aa) SNDQSFSSVAELVEHY . .. |.|..|||||| TGRHKFCSLQELVEHY |
|||||||||