Gene DCLK2 (Human)

DCLK2

Species: Human
Alias: DCAMKL2, DCLK2
External Links:
Annotation:

Classification

Group: CAMK
Family: DCAMKL

Sequence

Name Sequence Type Origin Length Description Download
DCLK2.AA Protein None 782 None Fasta, JSON
DCLK2.NA RNA None 3659 None Fasta, JSON
DCLK2.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of DCLK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DCX DCLK2.AA DCX 67-158 44 1.1e-44 155.66 SMART 1-96 (96) Show / Hide 
Range on Protein: 67-158
Range on HMM: 1-96/96
Sequence Identity: 44% (43 aa)

SEKKAKKARFYRNGDRYFKGLVFAISSDR-FRSFDALLIELTR-SLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEG-ESYVCASNE-PFRKVDYT
...|.|. .||||||..||| ...|.... |.|||.|| ..|. .|......|.|||.|||.||...||||||. .| ..|||.... .|..|||.
HHWKPKRICFYRNGDPFFKGVRLVINRKWQFKSFDHLLQDVTQTKLHVKMDCPHGVRHIYTTDGRHRVTSLDEFEDGDDFYVCCCTNEKFKPVDYD
DCX DCLK2.AA DCX 89-153 52 6.9e-35 125.38 Pfam 1-68 (68) Show / Hide 
Range on Protein: 89-153
Range on HMM: 1-68/68
Sequence Identity: 52% (36 aa)

FAISSDRFRSFDALLIELTRSLSDNVNLPQG-VRTIYTIDGSRKVTSLDE-LLEGESYVCA-SNEPFR
......||..||||| ..|.||.|.|.||.| ||.||| ||...|||||| |..|..|||. .||.|.
MVVNRRRFKTFDALLDDITESLHDKVQLPFGAVRKIYTPDGGHRVTSLDEFLQDGGCYVCCCGNERFK
DCX DCLK2.AA DCX 192-280 32 1.1e-38 135.72 SMART 1-96 (96) Show / Hide 
Range on Protein: 192-280
Range on HMM: 1-96/96
Sequence Identity: 32% (31 aa)

DFIKPKLVTVIRSGVKPRKAVRILLNKKT-AHSFEQVLTDITE---AIKLDSG-VVKRLCTLDG-KQVTCLQDFFGDDDVFIACGPE-KFRYAQDD
.. ||| ....|.|....|.||...|.|. ..||...|.|.|.   ..|.|.. .|... |.|| ..||.|..|...||....|. . ||.....|
HHWKPKRICFYRNGDPFFKGVRLVINRKWQFKSFDHLLQDVTQTKLHVKMDCPHGVRHIYTTDGRHRVTSLDEFEDGDDFYVCCCTNEKFKPVDYD
DCX DCLK2.AA DCX 214-275 32 3.3e-25 91.44 Pfam 1-68 (68) Show / Hide 
Range on Protein: 214-275
Range on HMM: 1-68/68
Sequence Identity: 32% (22 aa)

ILLNKKTAHSFEQVLTDITE----AIKLDSGVVKRLCTLDG-KQVTCLQDFFGDDDVFIAC-GPEKFR
...|......|...|.||||    ...|..| |....|.|| ..|| |..|. |......| | |.|.
MVVNRRRFKTFDALLDDITESLHDKVQLPFGAVRKIYTPDGGHRVTSLDEFLQDGGCYVCCCGNERFK
Kinase DCLK2.AA DCAMKL 410-667 65 2.3e-219 689.92 In-house 1-279 (279) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-279/279
Sequence Identity: 65% (182 aa)

YKIGKVIGDGNFAVVKECIDRSTG-KEFALKI-----------------IDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGG
|.||..|||||||||.||..|.|| ...|.||                 |||.||.||||.|.|||||....|||.||.|.|...|.|...||||.|.||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

DLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYTVCGTPTYVAPEIIAETGYGLKV
|||||||..||.||||...|...|..||.||| ..||||||||||||||...||.|||||.|||||..|.|   ||||||||||||||||..|||||.||
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV

DIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWV
||||||||.||||||||||||..| ||.|||||..||.|||.||||||.||||.|||.||||..|.|.||.||..||||
DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase DCLK2.AA CAMK1 410-667 42 8.49999999999e-141 412.04 In-house 1-276 (276) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-276/276
Sequence Identity: 42% (119 aa)

YKIGKVIGDGNFAVVKECIDRST---GKEFALKIID-KAKCCGKE----HLIENEVSILRRV---KHPNIIMLVEEMETATELFLVMELVKGGDLFDAIT
|..||.|| | |..|..|....|   ||..|.|.|| |    .|.     ..|||..|...|   .||||| . |  |. ... ||||||.||.||| | 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

SSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLK--LGDFGLATVVE-G--PLYTVCGTPTYVAPEIIAE---TGYGLKVDI
  ..|||.| .  . ... |. |.| . |||||.|||||| .. .|    .|  . ||||.. .. .   ..|.|||| |||||...    ..|. ..|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLL-YYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM

WAAGVITYILLCGFPPFRSEN-NLQEDLFDQILAGKLEFPAPYWDNITDS-AKELISQMLQVNVEARCTAGQILSHPWV
| .||||||||||.||| .|| . .  ||..|. ...||| |.|||| |. ||..|..|| |. . | |. |.| |||.
WSIGVITYILLCGYPPFYDENVDNE--LFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase DCLK2.AA CAMK 415-667 26 2.1e-126 409.54 In-house 1-425 (425) Show / Hide 
Range on Protein: 415-667
Range on HMM: 1-425/425
Sequence Identity: 26% (111 aa)

VIGDGNFAVVKECIDRSTG------------KEFALKIIDKAKCCG---------------------------KEHLIENEVSILRR-------VKHPNI
..| |.|..||.||...|.            ...| ||||| |  .                           ... ...|..|...       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IMLVEEME------------TATE--------LFLVM---ELVKGG----DLFDAITSSTK---------------YTERDGSAMVYNLANALRYLHGLS
| | | .|            | .         ...||   |.. ||    |||| |.. ..               .|||. . ..  .. |..|.| . 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKPENLLVCEYPDGT-------------KSLKLGDFGLATVVEG--------------------------PLYTVCGTPTYVA-PEIIA------
|||||.||||.|...  |..               .|. |||.|.....                          ...|.|||| |.| ||..       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ETGYGLKVDIWAAGVITYILLCGFPPFRSENN-----------LQEDLFDQILAGKLEFPAPY------------WDNITDS--------AK
        ...|| |.|.|..|||.||.|||.|||.....            ...|| .|..|| .|| ||            ||.|.|.        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

ELISQMLQVNVEARCTAGQILSHPWV
 ||..||||. | | |. |.|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DCLK2.AA RAD53 410-667 36 4.3e-123 368.66 In-house 1-305 (305) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-305/305
Sequence Identity: 36% (112 aa)

YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDK-------AKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETA-TELFLVMELVKGGDLFDAITSST
| ..|..| |||..||......|.. .| |||||        .  .|.  ..||| ||....||.|| . .  .|. . ...|.||. ||.||. | |. 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

K----YTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGT--------------KSLKLGDFGLATVVEGP--LYTVCGTPTYVAPEIIAE
.    ..| .. .  | . .|..||| . |.|||.|||| |  .. ...               ..|. ||||. .|.    . | ||||.|||||.|. 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

---------------TGYGLKVDIWAAGVITYILLCGFPPFRSENNLQ----EDLFDQILA-GKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQI
               .||. |||.| .|.|.||.|||.||| |.   |     .||.||.  ||..|| |||| |...|| ||..||.|..|.| |. ..
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPF-SDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LSHPWV
|.||| 
LNHPWM
Kinase DCLK2.AA S_TKc 410-667 34 2.9e-103 350.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-231/231
Sequence Identity: 34% (95 aa)

YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKG--GDLFDAITSSTK-----
|.|...|| | |..|. |....||...|.|||.          |..|..||.. .||||. | . ... ..|..|||.. |  ||||| | .  .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-YTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGL-KVDIWAAGVITYIL
 ..| .   ..| ...|| |.| . |.|||.||||.|..|       .|..|||||...    .|.|||| |.|||..   |||  |.|.|. |.| |..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILS-------HPWV
||| |||.     .. .|..|.              ...||..|...||.. | | || ..|        |||.
LCGYPPFP----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DCLK2.AA CAMK-Unique 410-667 27 1.7e-98 325.74 In-house 1-363 (363) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-363/363
Sequence Identity: 27% (99 aa)

YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCC-GKEHL------------------IENEVSILRRVKHPNIIMLVEE----METAT-------
|| ...||.||| .|.||.||.|||..| |.. |..    | ..                   ..|..|...|.||||| |..      ....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------ELFLVMELVKGGDLFDAITS--------------------STKYTE--RDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDG----
        ....|||.. ||||||.| .                     ....|  .| .  .  |. |. |.| ..|||||.|.||..||. ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------TKSLKLGDFGLATVVE-GPLY----TVCGTPTYVAP--------------EIIAETGYGLKV----DIWAAGVITYILLCGFPPFRSENNLQ
         . .|| ||||.. ..    .    |.|||| |.||              |.|.. .|. ..    |||. |||.|..||| ||| .|..  
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

------EDLFDQILAGKL-EFPAPYWDN---ITDSAKELISQMLQVNVEARCTAGQILSHPWV
        .|. |..|.. .|. ..|.    |...|| .. . ..| .  | .| ..|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase DCLK2.AA CAMKL 410-667 34 3.8e-94 300.85 In-house 1-297 (297) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-297/297
Sequence Identity: 34% (105 aa)

YKIGKVIGDGNFAVVKECID-RSTGKEFALKIIDKAKCCGKEHLIEN--------------EVSILRRVK---HPNIIMLVEEM-------ETATELFLV
|.|||..| |.|..|| ... | ||.. | ||||| |.. ...   |              |..|.....   ||||| | | .       || ....||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MELVKGGD--LFDAITSS----TKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKS--LKLGDFGLATV---V----EGPLYTVCG
||.. ||.  ||| | .      . .|..   .   .  |. |.| . ||||||||||.|.    |  ..  .|. |||...    .    .  | | ||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILL----DENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TPTYVAPEIIAE--T-GYGLKVDIWAAGVITYILLCGFPPFRSENN------LQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQ
.| | ||||..   .  .| |||||..||| | ..||  ||. ...       .  |. .|  |  ..| .|   .  ... ||..||||| | | |. |
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYH--VS-DCRDLIRKMLQVNPEKRPTIHQ

ILSHPWV
|..|||.
IMNHPWM
Kinase DCLK2.AA Pkinase 410-667 34 6.1e-93 319.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDK--AKCCGKEHLIE-NEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGG----DLFDAIT--SS
|.||..|| |.|..|..|....|||..|.|||.|  .|.. .....  .|..|..|..||||. | . .|. ... .|||.. ||    |||| |.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TKY--TERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA----TVVEGPLYTVCGTPTYVAPEIIA-ETGYGLKVDIWAA
...  .|..   ..| .. .| |.|  .|.|||.||||.|. . ..   ..|..|||||    .   . ..|.|||| |.|||.|   ..|| |||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVITYILLCGFPPFRSE----NNLQEDLFDQILAGKLEFPAPYWDNIT-----------------DSAKELISQMLQVNVEARCTAGQILSHPWV
|.| |..||| |||...    |. |  ....|. ..|.|. |.|..|                  ...|..|. .|... . |.|| ||| |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DCLK2.AA CDPK 410-667 37 2.6e-87 267.84 In-house 1-271 (271) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-271/271
Sequence Identity: 37% (103 aa)

YKIGKVIGDGNFAVVKECIDR-STGKEF-ALKIIDKAKCCGKEH-LI-ENEVSILRRVKHPNIIMLVEEMETATELFLVME--LVKGGDLFDAITSSTKY
|||.||.| |.| .|. .... .|. |  | ||| | ..  ||   .  ||. ||.   ||||| . |  .     ..|||  ...||.||| |..  ..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

TERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGT---KSLKLGDFGLATVVE-------GPLYTVCGTPTYVAPEIIAETGYGLKVDIWAA
||.. .  .. . .|. | |   |||||.||||.| .   |..   . .|. |.|...  .         ... ||||.|.|||..    |  |.||| .
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWV
||| |||||| |||  .|  ... ....  || .|  | ||.|.|.|| ||..||... . | .| |.| |||.
GVILYILLCGYPPFYGKN--DQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase DCLK2.AA RSK 412-667 29 5.9e-86 291.88 In-house 1-278 (278) Show / Hide 
Range on Protein: 412-667
Range on HMM: 1-278/278
Sequence Identity: 29% (82 aa)

IGKV--IGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK----EHLIENEVSILRRVK-HPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTK--
.     .| | . ....|... ||...| |...||| . .    .|  . |..|| |.. ||.|. | .  .| ..|.|.||...||.||. .       
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMT-ERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-YTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATV--VE--GPLYTVCGTPTYVAPEIIA----ETGYGLKVDIWAA
  .|.. ..  .... |...|| . |.|||.|||| |  .   .  ..|| |||..     .  ....| |.|  |.|||...    . |..  .|.|  
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GVITYILLCGFPPFRS-ENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCT-----AGQILSHPWV
||. | .| |.|||.. . | .......|. ||. .. | |..... ||.||..||... . | .     | .|..||| 
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase DCLK2.AA MARK 410-667 35 8e-83 270.57 In-house 1-262 (262) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-262/262
Sequence Identity: 35% (97 aa)

YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCG-KE-HLIENEVSILRRVKHPNIIMLVEEME--TATE-LFLVMELVKGGDLFDAITSS--TK
||..|.|| |..|.|| .... ||...|.||..| |    ..   .. |..|.....||||| | . .|  | .  ..|.||.. ||.|.| | .    .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

YTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTK--SLKLGDFGLATVV-EGP-LYTVCGTPTYVAPEIIAETGYG-LKVDIWAAGVIT
 .|..  ..   .  |. |.|  .||||||||||.|.    |  .    |. |||... . .|  | | |||| | ||||.    |   |||||. ||. 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI----DENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVL

YILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWV
|...||  ||.  .. ...|. .||.|| ..|      . .... ||...|.|| | | |. .|..|||.
YFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase DCLK2.AA RSK 410-667 33 3.9e-78 265.9 In-house 1-271 (271) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-271/271
Sequence Identity: 33% (91 aa)

YKIGKVIGDGNFA---VVKECIDRSTGKEFALKIIDKAKCCGK-EHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTE
| . ..|| | |    |.| |. . |....| |||.||.   |     |.|  ||| . ||.|. | .  .... ....|.. .|||||| .      .|
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSE

RDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA---TVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLC
|. ..  ...|.|. ||| . ||||| |||| |. .      ..|. |||.|      .| |.| |.|  |.|||..   |..  .|.|  ||. |. | 
REVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLT

GFPPFRSENNLQEDLFDQIL---AGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTA-----GQILSHPWV
|..|| . ..  ......|.    |.. .  ..||.|.| ||.|...|| .. . | .|      ||..|||.
GCTPFQNKPR--DTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase DCLK2.AA TyrKc 410-667 21 1.4e-14 12.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 410-667
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRV--KHPNIIMLVEEMETA-------TELFLVMELVKGGDLFDAITSS
 . ||..| |.| .| ... .    . | | . . .    .  . .| .|....  .||||. |.    .          |..|||....||| | . ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

TK-YTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP-------LYTVC----GTPT-----YVAPEIIAETG
 .  . .|   . .  |.  .|||   ..|||.   | || |        | .||||.  ..          | .     |. |       ||| | .  
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGLKVDIWAAGVITY-ILLCGFPPFRS-EN--NLQEDLFDQILAG-KLEFPAPYWDN-----ITDSAKELISQMLQVNVEARCTAGQILSHPWV
.  | |.|. ||  . |.  | .|    .      .... .. .|  .. |. .         .|   ....|  . . | |.|  .|  |   
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DCLK2.AA Pkinase_Tyr 410-592 26 7.1e-14 47.61 Pfam 1-199 (270) Show / Hide 
Range on Protein: 410-592
Range on HMM: 1-199/270
Sequence Identity: 26% (55 aa)

YKIGKVIGDGNFAVVKECIDR----STGKEFALKIIDKAKCCGKEH-----LIENEVSILRRV-KHPNIIML---VE-EMETATELFLVMELVKGGDLFD
 ..||..| |.| .|.... .    .|. . | |.. |   . .|.     ... |..|..   .||||. |   .  . |   ....|||....||| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLD

AITS----STKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-EGPLY-TVCG---TPT-YVAPEIIAETGYG
   .      . |  |   | .  |... ||.   ..|||.   | || |    ..  | .|||||  . .   | .. |    |    ||| |..  . 
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT

LKVDIWA
 | |.|.
TKSDVWS