n810

Species: Tetrahymena
Alias: 810, n810, 22.m00330
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
n810.AA Protein None 523 None Fasta, JSON
n810.NA RNA None 1572 None Fasta, JSON

Protein domain

Protein domains of n810.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n810.AA Ciliate-C8 49-244 20 2.7e-25 87.75 In-house 1-238 (238) Show / Hide
Range on Protein: 49-244
Range on HMM: 1-238/238
Sequence Identity: 20% (50 aa)

GLNSLVLK-----VNDDTALKIMKVTNQN-LELLKELDQRVSNLRTAGKNNYVQQVDSSYFLSENISNTS---------------TPVFYVQEMDLCT--
|  ..|||      |   |||. ...|..     ... ..   ..   .  .| ||  ...|.| ..                    .|.| || .|   
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKK-SFFVMEMEKCQQN

GNLDSYLSGLNQKEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNGQIVFKIAD------LGLYRLEDFSKWNIQGRLNRNAQKTID
.||..|.  . .|.. ... . | |||| .| .  .| | ..|  ||. |.|. .. ..|   |..|      .|. .    .|  .  .   . . .|.
CNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIE

I-------YQPQEAYYNQYSSKSDLFC-------LGLIF
        | . | ...|.  .||.|.       .||..
MYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL

Kinase n810.AA C2 49-256 22 7.1e-25 81.99 In-house 1-245 (245) Show / Hide
Range on Protein: 49-256
Range on HMM: 1-245/245
Sequence Identity: 22% (54 aa)

GLNSLVLKV-----NDDTALKIMKVTNQNLELLKELDQRVSNLRTAGKNNYVQQVDSSYFLSENISNT--------------------STPVFYVQEMDL
|  .||||.     | ..|||| ..   .... .|. . .. .|      |. .|  ...|..| .                         .|.| |.  
GAFGLVLKAFNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQEF

CTGNLDSYLSGLNQKEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNGQIVFKIAD----------LGLYRLEDFSKWNIQGRLNRN
|.||| .|.. . .... ... . . .||| .|.   .| |...|  ||. |.|| .. .|  . |..|          .   .    .| .| .     
CQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFKW

AQKTIDIYQPQEAYYNQYSSKSDLFC-LGLIFLQLENTN-FDFQN
 | ..      | | | |  .||||. .|...| | |.. .... 
TQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC

Kinase n810.AA C8 40-244 24 1.6e-21 71.57 In-house 1-226 (226) Show / Hide
Range on Protein: 40-244
Range on HMM: 1-226/226
Sequence Identity: 24% (57 aa)

YSSYEFVGAGLNSLVLKV-----NDDTALKIMKVTNQ----NLELLK---ELDQRVSNLRTAGKNNYVQQVDSSYFLSENIS-----NTSTPVFYVQEMD
 .....   |  ..|||      | . .||..|..|.    |.| ..   |..| ..       .. ... . . |  |. |      |    . |.||.
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME

LCTGNLDSYLSGLNQKEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNGQIVFKIADLGLYRLEDFSKWNIQGRL-NRNAQKTIDIY
||  ||  .   . .|.| ... . | ||||..| .  || . ..|  ||. |.| ... |     |..|.|.      .|  || .  |       . |
LCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNT---CGTWAY

QPQEAYYN------QYSSKSDLFCLGLIF
   |  .       ||. .|||| .||. 
FAPEIEKKQDNQYKQYRIQSDLFSVGLVL

Kinase n810.AA Ciliate-E1 116-238 20 6.2e-17 51.99 In-house 71-202 (202) Show / Hide
Range on Protein: 116-238
Range on HMM: 71-202/202
Sequence Identity: 20% (27 aa)

FYVQEMDLCTGNLDSYLS---------GLNQKEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNGQIV-FKIADLGLYRLEDFSKWN
.... ...|  .|  ||.          ..|........| ..|..||.|.| ..|....|| .|| .|||.. |.|...  | |.... .  .. .. .
ICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYK

IQGRLNRNAQKTIDIYQPQEAYYNQYSSKSDLF
 .    .  ..  ...| .. . .... |||..
GYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY

Kinase n810.AA S_TKc 40-313 17 1e-09 -34.4 SMART 1-231 (231) Show / Hide
Range on Protein: 40-313
Range on HMM: 1-231/231
Sequence Identity: 17% (52 aa)

YSSYEFVGAGLNSLVLKVNDDT-----ALKIMKVTNQNLELLKELDQRVSNLRTAGKNNYVQQVDSSYFLSENISNTSTPVFYVQEMDLCTG---NLDSY
|   . .| |  . | |. .       |.||.|         . . . .. |.  .  | |.  |. .          . .. |  |..| |   .| .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMV--MEYCDGDLGDLFDY

LSGLNQ--KEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNGQIVFKIADLGLYRLEDFSKWNIQGRLNRNAQKTIDIYQPQEAYYN
.   .   . . ..  .  ... |...||  .|  |.||  .|  |||  |      . ||.| || |.             .    | .   |      
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------------TTFCGTPWYMAPEVL---

QYSS-KSDLFCLGLIFLQLENTNFDFQNMQISEFVAFQNKLDKNEFPFEESLLKDSLLSQIIQEWLKDIPSERKDEKAVLA-------HLLL
.|.  |.|   .| |.  .      |.     ... |.. .             .. . ..|.  |.  |..|     .|.       |  .
GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase n810.AA Ciliate-E2 121-313 17 4.7e-09 27.22 In-house 113-365 (365) Show / Hide
Range on Protein: 121-313
Range on HMM: 113-365/365
Sequence Identity: 17% (49 aa)

MDLCTG-NLDSYLS--GLNQKEQ-----SLNDTQNERIAIQLLD---------------ALMIIHAFG-FIHNNIKLTNILYKEQSNGQIVFKIADLGLY
|..| | .| .|.    ......     .... .  .|  |.|.               ||  .|  .  || .||. |||.          ||.|.|| 
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLS

RLEDFS----------KWNIQGRLNRNAQKT----------------IDIYQPQEAYYNQ----------YSSKSDLFCLGLIFLQLENTNFDFQNMQIS
.  | .          || .. . ... . .                   |.. | . ..          |. |.|...|| |. ..   .. |      
KKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------

EFVAFQNKLD-KNEFPFEE-------------SLLKDSLL-SQIIQE----WLKDIPSERKD-EKAVLAHLLL
    .|.... | .||..|             | .| |.   ..|.      |.  |..| .  . .| |  .
----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase n810.AA ULK 121-195 24 9.5e-07 19.68 In-house 99-188 (329) Show / Hide
Range on Protein: 121-195
Range on HMM: 99-188/329
Sequence Identity: 24% (22 aa)

MDLCTG-NLDSYLS-----GLNQ-KEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNG--------QIVFKIADLGL
|..| | .|..|..     .... ... |.  .   . .|.| ... .|  . ||  ||. ||| ..   .        ..|.|||| |.
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGF

Kinase n810.AA Ciliate-E3 121-195 30 1e-06 17.15 In-house 83-152 (202) Show / Hide
Range on Protein: 121-195
Range on HMM: 83-152/202
Sequence Identity: 30% (23 aa)

MDLCTG-NLDSYLSGLNQKEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNGQIVFKIADLGL
...|.  .|  |.  .|. .. . |     |.||..  ...||.   ||  ||  |||   ..|.|.. ||.|.|.
QEYCSNGDLYHYIKQQNKTQNIIYD-----ICIQIIQGMIAIHEKNIIHSDIKPDNILV-DKNNNQLIIKICDFGE

Kinase n810.AA Ciliate-E2-Unclassified 121-313 15 2e-06 18.29 In-house 100-352 (352) Show / Hide
Range on Protein: 121-313
Range on HMM: 100-352/352
Sequence Identity: 15% (39 aa)

MDLCTG-NLDSYLSGLNQ---------------KEQSLNDTQ---NERIAIQLLDALMIIHAFG-FIHNNIKLTNILYKEQSNGQIVFKIADLGLYRLED
|..| | .|  |..  ..               |. . . ..    .... |.|..|  .|  . .|| .||. |||.... .     ||.|.|. .  .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKKYQ

FSKWNIQGRL--------NRNAQKTI--DIYQ----PQEAYYN-QYS----SKSDLFCLGLIFLQLENTNFDFQNMQISE----------------FVAF
 .  .  ..         . ... ..   .|.    . | . . .|.     |.| ..|| |. ..   .. |.  .  .                .   
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

QNKLDKNEFPFEE-------SLLKDSLLSQIIQEWLKDIPSERKDEKAVLAHLLL
... . . ..|..       |     ......|  ||  |..| . . .| | ..
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase n810.AA CK1 149-177 51 5e-06 17.01 In-house 136-164 (339) Show / Hide
Range on Protein: 149-177
Range on HMM: 136-164/339
Sequence Identity: 51% (15 aa)

RIAIQLLDALMIIHAFGFIHNNIKLTNIL
.||||.|.||  .|  |||| .|| .|..
MIAIQMLEALEYMHDCGFIHRDIKPDNFC

Kinase n810.AA NKF4 121-195 35 6e-06 14.61 In-house 114-190 (336) Show / Hide
Range on Protein: 121-195
Range on HMM: 114-190/336
Sequence Identity: 35% (28 aa)

MDLCT-GNLDSYLSGLNQKEQSLNDTQNERIAIQLLDALMIIHAFGFIHNNIKLTNILYKEQSNGQ----IVFKIADLGL
|| |  | .  ||  |  ... |||  .  . .||  |.   |  . ||.  |  ||.  |   ||     | |.|| ||
MDFCDGGDMNQYL--LSRHPR-LNDDTYKSFMMQLAQAMAHLHKNHIIHRDLKPYNIIIVEGRKGQSDLEPVVKVADFGL

Kinase n810.AA Ciliate-E3 228-248 38 0.035565 2.93 In-house 182-202 (202) Show / Hide
Range on Protein: 228-248
Range on HMM: 182-202/202
Sequence Identity: 38% (8 aa)

YNQYSSKSDLFCLGLIFLQLE
..| |  ||.  .| .|.|| 
QQQISKESDYYSVGAVFCQLC