Gene n819 (Tetrahymena)

n819

Species: Tetrahymena
Alias: n819, 819, 212.m00071
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-F2

Sequence

Name Sequence Type Origin Length Description Download
n819.AA Protein None 635 None Fasta, JSON
n819.NA RNA None 1908 None Fasta, JSON
n819.kin_dom Protein Kinase Domain None 109 None Fasta, JSON

Protein domain

Protein domains of n819.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n819.AA Ciliate-A8 41-180 27 4.1e-13 42.25 In-house 1-151 (151) Show / Hide 
Range on Protein: 41-180
Range on HMM: 1-151/151
Sequence Identity: 27% (43 aa)

YQIEQMIGTN-FGDCIVSVKDSQNQVYAIKIINY-ESFQVLDDT--QQAKSTYDSYKENKYILQTERYLVNKQIKSIFAVRELCDC--------SLRDFI
| ..  .. . |   ..  .   ..  |||||.| . .. . |      ...    |  |||||.   ...|... |  | |.|||        .|   .
YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFYKKKENLASIL

N--ANTLAKNQIFAITKQLLEGLISIRKARNNQQINTNIKPENILYKKSNNAFL
.   |..   || |.|.|||..|.   .   .  |  .|||.|||| .|.| |.
ENNLNKFTFEQIVALTYQLLKCLLVFQE---KGIIHCDIKPQNILYSWSKNQFI
Kinase n819.AA Ciliate-E1 47-233 24 1.3e-12 37.73 In-house 1-202 (202) Show / Hide 
Range on Protein: 47-233
Range on HMM: 1-202/202
Sequence Identity: 24% (50 aa)

IGTN-FGDCIVSVKDSQN-QVYAIKIINYESFQVLDDTQQAKSTYD---SYKENKYILQTERYLVNKQIKSIFAVRELCDCSLRDFIN------------
|| . |.. .  .....| ...|.||||.. ... .. |. .  |.   ..|...||.|   |.  .|.. . .. |.|.||| | ..            
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ

--ANTLAKNQIFAITKQLLEGLISIRKARNNQQINTNIKPENILYKKSNNAFLFSDLDCPIEALIQNQQTVQMIKYTTLKQSQISLYSSPEVTRNYEN--
   | .   |. .|..||..||| ..  ..   |  .|||.|||.... . ....|. .    |. ||.  . .|. | . ..   | .||.   ..|  
QNQNQFTFQQKMQIIFQLIDGLIELHQYNI---IHRDIKPQNILINNQ-GNYVYCDFGI-SKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQK

FSNKTDLF
 . |.|..
INYKSDIY
Kinase n819.AA S_TKc 41-306 17 3.1e-10 -26.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 41-306
Range on HMM: 1-231/231
Sequence Identity: 17% (48 aa)

YQIEQMIGT-NFGDCIVSVKDSQNQVYAIKIINYESFQVLDDTQQAKSTYDSYKENKYILQTERYLVNKQIKSIFAVRELCDC---SLRDFINANT----
|.| . ||   || .   .. . ....|||||.       .....  .   .    ..| .   . ..   .... | |.||    .|.|.|  .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LAKNQIFAITKQLLEGLISIRKARNNQQINTNIKPENILYKKSNNAFLFSDLDCPIEALIQNQQTVQMIKYTTLKQSQISLYSSPEVTRNYENFSN-
   .   ..  ...|....|  . .   .. |   .||||||  .       .|     .                  .     | .|||      ..  
RFPFPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE---HIKICDFGLARQL---------------TTFCGTPWYMAPEVL----GYGKC

KTDLFSLGLSLAELIRGKKFLNHQLQDIRDRDCLKRYLPKNTHYEDYIDKILINMVKVKPEDRLDPQSLLD----ILQEKFQ
| |  |.|  |.|.. |.     |.| . .. .           .. .| .. .. .. ||.|.    .|     | .  . 
KCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase n819.AA Ciliate-C5 93-313 26 1.7e-09 27.17 In-house 48-260 (260) Show / Hide 
Range on Protein: 93-313
Range on HMM: 48-260/260
Sequence Identity: 26% (59 aa)

KENKYILQTERYLVNKQIKSIFAVRELCDCSLRD-----FINANTLAKNQIFAITKQLLEGLISIRKARNNQQINTNIKPENILYKKSNNAFLFSDLDCP
|.  |.... . ..|..    . .     |.|.|     | .  ||. |||  .  |.      |..   |. |   .|||||||      |  .|    
KDTPYVFKSIEEFLNEKKSKYYQISKRYSCNLKDIMQSFFDQKKTLPLNQIIGFAIQMSTVFEKIQQ---NNLIHSDVKPENILYDSQEKCFNLCDY-GE

IEALIQNQQTVQMIKYTTLKQSQISLYSSPEVTRNYENFSNKTDLFSLGLSLAELIRGKKFLNHQLQDIRDRDCLKRYLPKNTHYEDYIDKILINMVKVK
   . .  .| ..  .|         |  ||.| .   |  | |.. ||. | ||  ||   ..    ||. . | .|. ||  |.| |..|.| |. . 
SKSFKDGSKTYDLKGFTR-------KYAAPEITDDNGFFNIKYDIYGLGIILLELTLGKFLEDEDCTFIRNGK-LPNYISKNALYQD-INQIIIKMLEKM

PEDRLDPQSLLDILQEKFQTTDQDLL
|..|.|   |   | |     .....
PQNRIDSFELTKQLNELRLKLESQFI
Kinase n819.AA Ciliate-F2 116-246 29 2.1e-09 30.46 In-house 75-200 (200) Show / Hide 
Range on Protein: 116-246
Range on HMM: 75-200/200
Sequence Identity: 29% (39 aa)

VRELCDCSLRDFINANTLAKNQIFAITKQLLEGLISIRKARNNQQINTNIKPENILYKKSNNAFLFSDLDCPIEALIQNQQTVQMIKYTTLKQSQISLYS
| |. ||....   .  |  ||..  . |...||  .    |   |   || ||..|..  . |.| |    |  |..  .         |.  ||  | 
VQETEDCCIKQQLQSCKLTDNQQYEEIQQFINGLAEL---ENLGLIHGDIKIENMIYNRPKQRFMFDDFQL-IQILMKSNKPASS-NSKQLQRTQI--YG

SPEVTRNYEN--FSNKTDLFSLGLSLAELIRGK
 ||. .  .   | || | . ||. |.|.| ||
APELEKEQDTSRFQNKMDTYALGMVLSEIIIGK
Kinase n819.AA Ciliate-B2 116-236 24 2e-07 13.43 In-house 79-197 (197) Show / Hide 
Range on Protein: 116-236
Range on HMM: 79-197/197
Sequence Identity: 24% (32 aa)

VRELCDCSLRDFIN----AN-TLAKNQIFAITKQLLEGLISIRKARNNQQINTNIKPENILYKKSNNAFLFSDLDCPIEALIQNQQTVQMIKYTTLKQSQ
. | | |||.. ..          .. .. .  ||..||| .|    .  .   |||.|||  ...| ....|    |  ... ..  . ||  | |   
IMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRM---YNILHLDIKPQNILFMQNGN-YVYCDFG--ISSIKK-DNQQIKIKGFTKK---

ISLYSSPEVTRNY------ENFSNKTDLFSLG
   | |||   .        |   . | .|.|
---YASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase n819.AA Ciliate-C8 118-239 18 2.2e-05 15.64 In-house 94-238 (238) Show / Hide 
Range on Protein: 118-239
Range on HMM: 94-238/238
Sequence Identity: 18% (27 aa)

ELCD--CSLRDFINA-----NTLAKNQIFAITKQLLEGLISIRKARNNQQINTNIKPENILYKKS-NNAFL--FSD----LDCPIEALIQNQQTVQMIKY
|.|.  |.| ....        . ... . |. | ....  .     .. .   |||.|.|.  . .. .    .|     |    . ......  ..| 
EKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHC---FNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKK

TTLKQSQISL-------YSSPEVTRN-----YENFSNKTDLFSLGLSL
   ..  |         |. |||  .     .  || | |..|.|| |
FKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase n819.AA PEK 213-243 31 2.8e-05 13.49 In-house 554-588 (655) Show / Hide 
Range on Protein: 213-243
Range on HMM: 554-588/655
Sequence Identity: 31% (11 aa)

LYSSPEVTRNY----ENFSNKTDLFSLGLSLAELI
||.|||.  .     ... .|.|..|||. ..|..
LYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMW
Kinase n819.AA PEK 212-243 29 0.000113 10.19 In-house 652-698 (758) Show / Hide 
Range on Protein: 212-243
Range on HMM: 652-698/758
Sequence Identity: 29% (14 aa)

SLYSSPEVTRNY---------------ENFSNKTDLFSLGLSLAELI
.|| |||  ..                 . ..|.| .|||| ..|||
HLYMSPEQCHHQSVFGTGTYTNPEQKKTWYNHKVDIYSLGLIFFELI
Kinase n819.AA Ciliate-E3 61-177 29 0.000127 10.67 In-house 22-141 (202) Show / Hide 
Range on Protein: 61-177
Range on HMM: 22-141/202
Sequence Identity: 29% (36 aa)

SQNQVYAIKIINYESFQV------LDDTQQAKSTYDSYKENKYILQTERYLVNKQIKSIFAVRELCDC-SLRDFINANTLAKNQIFAITKQLLEGLISIR
..||. ||| |  .  |.      . .|||      .  . ..... .  .. .| |.|| | |.|   .|  .|    . .| |  | .|...|.| | 
QNNQDVAIKAIICQNQQNEGVGEQFQKTQQEFQNCQQI-NSQNVVKCHDQYYDQQNKMIFIVQEYCSNGDLYHYIKQQNKTQNIIYDICIQIIQGMIAIH

KARNNQQINTNIKPENILYKKSNN
     . |   |||.|||  |.||
E---KNIIHSDIKPDNILVDKNNN
Kinase n819.AA TKL 214-301 18 0.000168 12.14 In-house 239-364 (364) Show / Hide 
Range on Protein: 214-301
Range on HMM: 239-364/364
Sequence Identity: 18% (23 aa)

YSSPEVTR---NYEN------------FSNKTDLFSLGLSLAELIRGK-KFLNHQLQ---------DIRDRDCLKRYLPKNT---------HYEDY----
. .||| |   ||..            .| |.| .| |. | |.. ..  . ..            ..   .|.|.. |              ...    
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPS

IDKILINMVKVKPEDRLDPQSLLDIL
. |..    . .||.|.  | .|..|
MKKLMQDCWDHDPEKRPSFQEILKRL
Kinase n819.AA PEK 118-149 19 0.00041 9.37 In-house 363-440 (655) Show / Hide 
Range on Protein: 118-149
Range on HMM: 363-440/655
Sequence Identity: 19% (15 aa)

ELCD-CSLRDFINANT---------------------------------------------LAKNQIFAITKQLLEGL
|.|. ..||| |. |.                                             ..|.|.. |..|.||||
EYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGL
Kinase n819.AA Ciliate-E3 205-243 25 0.000718 8.29 In-house 165-202 (202) Show / Hide 
Range on Protein: 205-243
Range on HMM: 165-202/202
Sequence Identity: 25% (10 aa)

TLKQSQISLYSSPEVTRNYENFSNKTDLFSLGLSLAELI
|. |   ..|..||.   . ..|.  |. |.|  . .|.
TQYQGWTPFYAAPEQND-QQQISKESDYYSVGAVFCQLC