Gene W04G5.10 (Nematode worm)
W04G5.10
Species: Nematode worm
Alias: W04G5.10, aSWK470
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| W04G5.10.AA | Protein | None | 397 | None | Fasta, JSON |
| W04G5.10.kin_dom | Protein Kinase Domain | None | 273 | None | Fasta, JSON |
Protein domains of W04G5.10.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | W04G5.10.AA | KIN16 | 100-379 | 47 | 1.4e-211 | 627.21 | In-house | 1-332 (332) | Show / Hide |
Range on Protein: 100-379 Range on HMM: 1-332/332 Sequence Identity: 47% (159 aa) ISTENYIGSGFFGTVYRAELRRE-----RRNSNFMIVAVKEPSNIHNIRQKKILHEELNVMCSMEKHPNILSLVG-VVTQRN------VMIVTEYVEDGD ...|...|||.||.|... |... ....|.. ||||.|.| |.|.|.|....||.|||...||||.|.||| |..... .||||||||.|| LEFEEPLGSGHFGVVRKGLLHMKNPKNEKEHKNRLEVAVKSPANPHDICQQKMIYDELKVMCAIGKHPNVLALVGAVTKNMRQGGRHMLMIVTEYVECGD LLKFLRKCK--FDKDSVKLDEK---------------------------------SLCKADLFSFTFQIANGMQYLERVPC-VHRDLALRNVLIKNNGVL |.||||... |... |. |.. ||| .||.||..||||||..|..||| ||||||.|||.|| | . LRKFLRQHRNNFQNHQVCWDNERQSGYNINNKERKHYVFKNFCENEQLVIKDIFDSLCTSDLLSFAYQIANGMEWLAHVPCCVHRDLACRNVFIKRNKII KIADFGLARRHDKKDYYRTKT-TDTALPIKWLAPECFEEEEEK-IRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNN--FAFLQVLADFLRKGNTLSEP ||||||||.| .|||||.|. .||.||..|.||||||||.|. ..|..|||||||||||||||||||.||.....|| ....|.....|||||.|..| RIADFGLARWHENKDYYRMKSSMDTPLPMRWMAPECFEEEQERKMKFTEKSDVWSYGVCLYEIFSLGETPYPNCPNNNCRDDYFQYVMEYLRKGNRLPQP EHCAPKMYYFMKSCWNLIPEERPSFTACTNFS ||| |..|.|||.|||..||.||.|. |..| EHCHPEIYDFMKMCWNFDPEKRPTFSECVEFF |
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| Kinase | W04G5.10.AA | TyrKc | 100-383 | 35 | 2.5e-111 | 377.05 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 100-383 Range on HMM: 1-280/280 Sequence Identity: 35% (109 aa) ISTENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQKKILHEELNVMCSM-EKHPNILSLVGVVTQ--------RNVMIVTEYVEDGDLLK |. . .|.|.||.||..... . |||| . . .. ...|...||. .||||. |.||.|| .|||.||.. |||.. ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD FLRKCKFDKDSVKLDEKSLCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKK-------DYYRTKT---TDTALPIK .|||.. . || .|| || .|||.||.||.. .|.||||| ||.|...|.. ||.||||.| .. . ||||.|. ..| |||. YLRKHRPK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR WLAPECFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKGNTLSEPEH--------CAPKMYYFMKSCWNLIPEERPSF |.||||. . .| .||||||.|||..|||..|..|| . . . | . ....|. . |.. | ..|| ||.||. ||.||.| WMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF TACTNFSRTQL ... . .. SEI----HECF |
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| Kinase | W04G5.10.AA | Pkinase_Tyr | 100-383 | 37 | 1.7e-108 | 368.04 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 100-383 Range on HMM: 1-270/270 Sequence Identity: 37% (109 aa) ISTENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQ--KKILHEELNVMCSMEKHPNILSLVGVVT--QRN--VMIVTEYVEDGDLLKFLR |. .|.| ||.||..... .. . |||| . . .| .. . .|...|... .||||..|.||.| .. ..||.||.. ||||..|| ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR KCKFDKDSVKLDEKSLCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKKDYYRTKTTDTALPIKWLAPECFEEEEEK | . |...|. || .. .|||.||.|||. .|.||||| ||.|...|.| ||.|||||| . ..||| .|.... |||||.||||. . . KHR-------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-- IRFDSKSDVWSYGVCLYEIFSLGESP-YNELDSNNFAFLQVLADFL-RKGNTLSEPEHCAPKMYYFMKSCWNLIPEERPSFTACTNFSRTQL | .||||||.||...|||..||.| | ... . . ... ..|. . ||.| ...| ||.||. ||.||.|... . || --FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEE------VYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI----HEQL |
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| Kinase | W04G5.10.AA | TK | 100-379 | 23 | 6.1e-103 | 346.0 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 100-379
Range on HMM: 1-486/486
Sequence Identity: 23% (115 aa)
ISTENYIGSGFFG---TVYRAELRR--ERRNSNF------------------MIVAVKEPSNIHNIRQK-KIL---------------HEELNVMCS-ME
| .. .|.| || .||..|.|. ....| . |||| .. |. ... ||. .||. .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
KHPNILSLVGVVTQRN-------------VMIVTEYVEDGD----LLKFLRKCKFDKDS-----------------------------------------
.||||..|.||.|| .|||.||.. || |...||||. ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
----VKLDEKSLCKADLFS-------------------FTFQIANGMQYLERVPC------VHRDLALRNVLIKNNGV-----------LKIADFG----
|... .|. .|| . . .|||.||.||.. .| |||||| ||.|. .|.| ||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ
----LARRHDKKDYYRTKT-----------------------TDTALPIKWLAPECFEEEEE-----KIRFDSKSDVWSYGVCLYEIFSLG-ESPYNELD
|||.....|.|..|. ... |||.|.||||... .. . .| .||||||.||...|||..| | .| ...
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS
SNNFAF---LQVLADFLRKG--------------NTLSEPEHCAP-------------KMYYF-MKSCWNLIPEERPSFTACTNFS
... . .| . ..||.| . . |.|| . ..|| |..||.. ||.||.|... ..
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
|
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| Kinase | W04G5.10.AA | TK-Unique | 100-377 | 33 | 1.5e-81 | 277.25 | In-house | 1-292 (294) | Show / Hide |
Range on Protein: 100-377
Range on HMM: 1-292/294
Sequence Identity: 33% (101 aa)
ISTENYIGSGFFGTVYRAELRRER-RNSNFMIVAVKEPSNIHNIRQKKILHEELNVMCSMEKHPNILSLVGVVT-QR-NVMIVTEYVEDGDLLKFLRKCK
. ...||.| ||.|.|.|... .. . .|||| .. .|. . |...| . .||||....|. | ..||. ||.. |.|...||.|.
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR
-------------FDKDSVKLDEKS--LCKADLFSFTFQIANGMQYLER--VPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKKDYYRTKTTDTALPI
|| .... . . ||..| .|||.||.||.. .|||||. ||||. ...|.||.|||.||. .. | .... .||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI
KWLAPECFEEEEEKIRF-DSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKGNTLSEPEHC-APKMYYFMKSCWNLIPEERPSFTACTN
.|.||| . . . . .||||||.|| ..|||.||. ||..... . . . .|.| .. |||| . ||..|||||.. |||||||.....
RWMAPESLKCY--HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD------IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKH
|
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| Kinase | W04G5.10.AA | UTK | 100-372 | 33 | 8.5e-71 | 241.41 | In-house | 1-289 (296) | Show / Hide |
Range on Protein: 100-372 Range on HMM: 1-289/296 Sequence Identity: 33% (100 aa) ISTENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQKKI----LHEELN---VMCSMEKHPNILSLVGVVTQ-RNVMIVTEYVEDGDLLKF . . .|.| ||.|..|...... . |.||||. .. .. .|.. . || . .| . |||.| ||||.|| |||||| |.|||... VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LRKCKFDKDSVKLDEKSLCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNG-------VLKIADFG---LARRHDK--------KDYYRTKTT ||... . . .. .| . .. .. .||.|||||.. .|||||| ||.|. .. | |||||| ..|| .|| ... LRRHRPTPP---ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH DTALPIKWLAPECFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKG-NTLSEPEHCAPKMYYFMKSCWNLIPEERPSF ....||.| |||.. . . || .||||||.|| ..||.. | || .. . ||.. ....| . |..| .| |..||. |.|||.| QDRWPIRWMAPEALTHHT---RFTTKSDVWSFGVVCWEIWTWGRLPYPGM-----SNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDF |
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| Kinase | W04G5.10.AA | Met | 101-373 | 32 | 4.6e-62 | 202.18 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 101-373
Range on HMM: 1-271/271
Sequence Identity: 32% (93 aa)
STENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPS--NIHNIRQKKILHEELNVMCSMEKHPNILSLVGVVTQRNV---MIVTEYVEDGDLLKFLRKC
.. || |.|| ||..... . .| .|.| . | | . .| .| . .|||.|||.|. . ..|..| . |||..| |
HFDDVIGQGHFGCVYHGMYHDN--DGNEHHCACKSLHGERITDIQHISQFLREGIMMKHF-DHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRN-
KFDKDSVKLDEKSLCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRH--DKKDYYRTKTTD-TALPIKWLAPECFE----
.. .| ||..| .|.| ||.|. |||||| || .. . |.|||||.| || | |. ||.||.|||| .
---------PQNNPCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVC
-EEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKG--NTLSEPEHCAPKMY-YFMKSCWNLIPEERPSFT
. | .|||||| || . | . | .|| . |. . .. .| | . |. ||.| . | | .|| ||.||.|
LGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDN----WFDITH-WLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS
|
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| Kinase | W04G5.10.AA | FGFR | 100-373 | 36 | 1.3e-61 | 208.71 | In-house | 1-287 (293) | Show / Hide |
Range on Protein: 100-373
Range on HMM: 1-287/293
Sequence Identity: 36% (107 aa)
ISTENYIGSGFFGTVYRAELR--RERRNSNFMIVAVKEPSNIHNIRQKKILHEELNVMCSMEKHPNILSLVGVVTQRN-VMIVTEYVEDGDLLKFLRK--
. .| | || | .|| . | . ..|||| | . | |. .| ||.||. | |. || .. || . | | |||.
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR
---CKFDKDSV-------KLDEKS--------LCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKKDYYRTKTTDTA
. .||| . |. | . || |...|.| ||.||. |.||||| ||||. . |.||.|||||| . |||| |||.
PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYR-KTTNGR
LPIKWLAPECFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKGNTLSEPEHCAPKMYYFMKSCWNLIPEERPSFT
||||| ||| . ....|||||||| | ||. .|..|| | | ..|. | . |..| .| | .|| |..||.|.
LPIKWMAPEALFDR----VYTHQSDVWSYGVLLWEIMTYGGQPYPHIPS-----VEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFK
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| Kinase | W04G5.10.AA | Src | 100-379 | 33 | 1.6e-61 | 207.78 | In-house | 1-255 (255) | Show / Hide |
Range on Protein: 100-379
Range on HMM: 1-255/255
Sequence Identity: 33% (95 aa)
ISTENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQKKILHEELNVMCSMEKHPNILSLVGVVTQR-NVMIVTEYVEDGDLLKFLRKCKFD
| . .|.| || |. . . . . |||| . . .. | .| ..| .. .|.....| |..| . ||||| . | ||..|.|
IKLCRKLGQGQFGEVWMGYWN------GNTKVAVKTLKPGT-MSPEAFL-QEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----
KDSVKLDEKSLCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDK-KDYYRTKTTDTALPIKWLAPECFEEEEEKIRFD
. ....| .| ... |.|.||.|||. .||||| ||||. .| | |.||||||| .. .| | .. . .|||| |||.. . ||
----DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH-GAKFPIKWTAPEAINYG----RFT
SKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKGNTLSEPEHCAPKMYY-FMKSCWNLIPEERPSFTACTNFS
||||||.|. |.||.. | || . | .. || .| . |..| ...| |. ||. ||.|| | .|
IKSDVWSFGILLTEIVTYGRVPYPGMT-NHEVLQQV-----ERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
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| Kinase | W04G5.10.AA | TKL | 106-373 | 21 | 7.5e-57 | 195.19 | In-house | 1-358 (364) | Show / Hide |
Range on Protein: 106-373
Range on HMM: 1-358/364
Sequence Identity: 21% (83 aa)
IGSGFFGTVYRAELRRERRNSN----FMIVAVKEPSNIHN-------------------------IRQKKILHEELNVMCSMEKHPNILSLVGVVTQRN-
||||.||.||....| .. |||| . .. ... . || .|.|. .||||....|.... .
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC
-------------VMIVTEYVEDGDLLKFLRKCKFDKDSVKLDEKSLCKADL-FSFTFQIANGMQYLER--------VPCVHRDLALRNVLIKNNGV---
.||.||.. |.|| .| .. ... .|| ||.|| | .|||| .|.|...|.
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS
-----------LKIADFGLARRHDKKD----------------YYRTKTTDTALPIKWLAPECFEEEE------------EKIRFDSKSDVWSYGVCLYE
.||.||||.|..... .|..| . |.|||...... .. .. |.||.|.|..|.|
NYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE
IFSLGESPYNELDSNNFAFL----QVLADFLRKGNTLSEP------------EHCAPKMYYFMKSCWNLIPEERPSFT
|.. . || ..... | . .. ||. . | ..| | | |. ||. ||.||||.
ILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQ
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| Kinase | W04G5.10.AA | EGFR | 100-379 | 34 | 9.1e-55 | 180.19 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 100-379
Range on HMM: 1-258/258
Sequence Identity: 34% (97 aa)
ISTENYIGSGFFGTVYRAELRRERRNSNFMI-VAVKEPSNIHNIRQKKILHEELNVMCSMEKHPNILSLVGVVTQRNVMIVTEYVEDGDLLKFLRKCKFD
. ||| |||||. | | | ||.|. . . .... . .| || |.. ||... |.|| . ....|| | | || ..|. |
LKKVKVLGSGAFGTVYKGIWIPE--GENVKIPVAIKVLREQTGPKANEEMLDEAYVMASVD-HPHLVRLLGVCMHSQMQLVTQYMPYGCLLDYVRQHK--
KDSVKLDEKSLCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLAR--RHDKKDYYRTKTTDTALPIKWLAPECFEEEEEKIRF
. .| . .||| |||||| |||||| ||||.| ||.|||||. ||.|.| . . .||||.| ||... ..
--------DNIGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEY---HAQGGKMPIKWMALECIHHR----CY
DSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKGNTLSEPEHCAPKMYYFMKSCWNLIPEERPSFTA-CTNFS
..|||||||| . |. |..||. . .. |.| ||. |. |. | .| | .|| . .. || | . |.
THQSDVWSYGVTCWELMTFGQKPYDGIP------AREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
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| Kinase | W04G5.10.AA | VEGFR | 213-372 | 44 | 5.9e-49 | 168.95 | In-house | 174-325 (332) | Show / Hide |
Range on Protein: 213-372 Range on HMM: 174-325/332 Sequence Identity: 44% (72 aa) DLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARR-HDKKDYYRTKTTDTALPIKWLAPECFEEEEEKIRFDSKSDVWSYGVCLYE || .. ||.|.|| .|. |.||||| ||.|. | |.|| |||||| | . | .|. . |||||.||| .|. . ..|||||||| | | DLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESI---FDKV-YTTYSDVWSYGVFLWE IFSLGESPYNELDSNNFAFLQVLADFLRKGNTLSEPEHCAPKMYYFMKSCWNLIPEERPSF ||||| ||| . . . . .|. |. . |. | | .| | .|| |||||.| IFSLGGSPYPGVQID-----EEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHF |
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| Kinase | W04G5.10.AA | S_TKc | 100-378 | 22 | 1.4e-36 | 128.77 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 100-378
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)
ISTENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQKKILHEELNVMCSMEKHPNILSLVGVVTQRNVMIVTEYVED--GDLLKFLRKCKF
. ||.| ||.||.. .. |||.|. . . . |.... . .|||| | .| .. .|.||.. |||.....|..
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGR
DKDSVKLDEKSLCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKKDYYRTKTTDTALPIKWLAPECFEEEEEKIRFD
. ....| .. .. ||.....|. . .|||| |.|. . ..||.||||||. | ..||| . ..
HGLRFPFPE-HARF-----YMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-------GYG
S-KSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRKGNTLSEPEHCAPKMYYFMKSCWNLIPEERPSFTACTN----------F
|.|.|| |..||| .. |. |. . .. .... | . |.. |.. ||.||. . . |
KCKCDWWSCGCILYEMLC-GYPPFP----QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | W04G5.10.AA | Pkinase | 100-375 | 23 | 1.6e-31 | 112.55 | Pfam | 1-287 (293) | Show / Hide |
Range on Protein: 100-375
Range on HMM: 1-287/293
Sequence Identity: 23% (74 aa)
ISTENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQKKILHE---ELNVMCSMEKHPNILSLVGVV-TQRNVMIVTEYVEDG----DLLKF
. .. |||| ||.||.. . ... |||||. . |. .|.. | |. .| .. .||||. | ... . ... .|.||.| | || .
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY
LRKCKFDKDSVKLDEKSL--CKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVL----KIADFGLARRHDKKDYYRTKTTDTALPIKWLAPE
.. ..... .. .. ||. |..|. . ..|||| . |.||.|||.. ||.|||||. .| . .|. . . ..|||
IST---------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPE
CFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNEL-----DSNNFAFLQVLADFLRKGNTLSEPEHCA-------------------PKMYYFMKSC
. ..|.|.||.|. ||| .. |. |. . .. .. . .. ... . ..|. | . . |.|.|
VIR---GGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRI----MGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC
WNLIPEERPSFTAC
... |..||... .
LCKDPKKRPTAEQI
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| Kinase | W04G5.10.AA | VEGFR | 98-193 | 27 | 0.002848 | 8.43 | In-house | 1-98 (332) | Show / Hide |
Range on Protein: 98-193 Range on HMM: 1-98/332 Sequence Identity: 27% (27 aa) LKISTENYIGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQKKILHEELNVMCSMEKHPNILSLVGVVT----QRNVMIVTEYVEDGDLLKFLR ||. .| | || | |. |. .. .|||| .. | || .. .| | .. | .| .. .|. ||. | |. .|| LKLG--KMLGRGAFGQVHEASAFGIRKMETCTTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLR |
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