Gene AqueK013 (A.queenslandica)
AqueK013
Species: A.queenslandica
Alias: AqueK013
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK013.AA | Protein | None | 348 | None | Fasta, JSON |
| AqueK013.kin_dom | Protein Kinase Domain | None | 110 | None | Fasta, JSON |
Protein domains of AqueK013.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK013.AA | PKA | 247-348 | 70 | 1.4e-81 | 277.33 | In-house | 71-173 (263) | Show / Hide |
Range on Protein: 247-348 Range on HMM: 71-173/263 Sequence Identity: 70% (73 aa) DNSYLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYAS-QIVLAFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFAKRVKGRTWTLCGTPEYLAPEII |..||||..|.|.||||||.||. ||||..|..||| |||||.|||| ..|.||||||||.|||. |..|.|||||||.|..||||||||||||||||| DDRYLYMVMEYVPGGEMFSYLRKSGRFSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEII LSK .|| QSK |
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| Kinase | AqueK013.AA | AGC | 246-345 | 32 | 2.2e-76 | 196.15 | In-house | 101-279 (395) | Show / Hide |
Range on Protein: 246-345 Range on HMM: 101-279/395 Sequence Identity: 32% (58 aa) EDNSY--LYMLLE----FVS-----GG-EMFSHLR---RIGRFSESHSRFYASQ-------IVLAFEYLHY-LDIVYRD-LKPENLLIDQHGYVKVTDFG .|... ||...| .|. || |.|.||. . |||.|...||||.. ||||.|||| ..|..|| |||||.|.|..|..| |||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG FAKRVKG-----------------------------------------------------RTWTLCG--TPEYLAPEII ..|.... ||||.|| ||||.||||. LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL |
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| Kinase | AqueK013.AA | SGK | 250-346 | 54 | 3.1e-60 | 184.5 | In-house | 99-198 (283) | Show / Hide |
Range on Protein: 250-346 Range on HMM: 99-198/283 Sequence Identity: 54% (54 aa) YLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIIL .||. ...| |||||.||.| ..|.|. .||||..||.| |||| .||.||||||||.| | |... |||| .| . | | ||||||||||... KLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR |
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| Kinase | AqueK013.AA | Akt | 247-346 | 50 | 1.1e-59 | 189.48 | In-house | 71-175 (264) | Show / Hide |
Range on Protein: 247-346 Range on HMM: 71-175/264 Sequence Identity: 50% (53 aa) DNSYLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYASQIVLAFEYLHYLDIVYRD-LKPENLLIDQHGYVKVTDFGFAK-R-VKG--RTWTLCGTPEYLA .. .||. .....||| |.||.| .||||. |||...|.|| |.|| .|.||| |||||.|.|..|....|||| .| .| .| |.|||||||| TQDKLYFVMDYCNGGELFYHLQRKRRFSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLA PEIIL |||.. PEILN |
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| Kinase | AqueK013.AA | AktR | 246-348 | 47 | 1.2e-53 | 184.58 | In-house | 71-180 (268) | Show / Hide |
Range on Protein: 246-348 Range on HMM: 71-180/268 Sequence Identity: 47% (52 aa) EDNSYLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYASQIVLAFEYLHYL-DIVYRDLKPENLLIDQHGYVKVTDFGFAK----R-VKGRTWTLCGTPEY .....|. ..|.. |||.|.||.....|||. .|||..||.||.||||. .|.||||||||.|.|..|.|| |||| .| . .. ..|||||| QTKEKLFFIMEYCPGGELFQHLKKKKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEY LAPEIILS-K .|||.|. | MAPEMITKKK |
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| Kinase | AqueK013.AA | PKG | 247-348 | 55 | 4.1e-49 | 169.47 | In-house | 71-174 (260) | Show / Hide |
Range on Protein: 247-348 Range on HMM: 71-174/260 Sequence Identity: 55% (58 aa) DNSYLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFAKRVK--GRTWTLCGTPEYLAPEI |. |.|||.| |||. . || |.| .. .|||. .| ||.||| |.|||||||||. |. ||.| ||||||... ..||| |||||| |||| DQKYVYMLMEACMGGELWTILRDRGHFDDKTTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEI ILSK || | ILNK |
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| Kinase | AqueK013.AA | Ciliate-E2b | 245-345 | 44 | 8.6e-49 | 146.47 | In-house | 69-177 (272) | Show / Hide |
Range on Protein: 245-345 Range on HMM: 69-177/272 Sequence Identity: 44% (48 aa) KEDNSYLYMLLEFVSGGEMFSHLRRIG--RFSESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFAKRVK---G---RTWTLCGT . |. ..|...||..|.|.|. .| || .|.. |.|| .|.|..|||| . |.|||.|||| ..|. ||.| |.| || . . || |..|| FKDDQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGT PEYLAPEII |.|.||||| PHYMAPEII |
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| Kinase | AqueK013.AA | RSK | 246-345 | 43 | 3.1e-44 | 153.29 | In-house | 71-180 (278) | Show / Hide |
Range on Protein: 246-345 Range on HMM: 71-180/278 Sequence Identity: 43% (48 aa) EDNSYLYMLLEFVSGGEMFSHLRRIGR---FSESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQ---HGYVKVTDFGFAKRV----KGRTWTLCG .....||. .|...|||.| ||.. .. |||. .||...|||| |.|| ..|..||||||| | |. .| .|.|||||.| ...| | |. QTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCY TPEYLAPEII | ||.|||.. TIEYMAPEML |
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| Kinase | AqueK013.AA | p70 | 247-346 | 44 | 5.6e-42 | 145.79 | In-house | 99-211 (299) | Show / Hide |
Range on Protein: 247-346 Range on HMM: 99-211/299 Sequence Identity: 44% (50 aa) DNSYLYMLLEFVSGGEMFSHLRRIGRFSESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFAKRV--KGRT-----------WTL .|. || .||. .||| | || | | . | .||.| |..| |.|| ..|.|||||||| . .| | |. |||| | .| .|. TNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTF CGTPEYLAPEIIL |||.|| ||||.. CGTIEYMAPEILM |
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| Kinase | AqueK013.AA | CAMK | 246-348 | 27 | 1.2e-40 | 128.27 | In-house | 127-295 (425) | Show / Hide |
Range on Protein: 246-348
Range on HMM: 127-295/425
Sequence Identity: 27% (47 aa)
EDNSYLYMLL---EFVSGGEM----FSHLRRI---------------GRFSESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQHG----------
......|| . |..||||. |..... |||.|. |.| ||. | .|.| ..|| |||||||.|.|...
TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDE
------Y-VKVTDFGFAKRVKG--------------------------RTWTLCGTPEYLA-PEIILSK
. .|..|||||..... .| |||||| | ||....|
IFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK
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| Kinase | AqueK013.AA | Pkinase | 246-348 | 39 | 2.9e-39 | 139.91 | Pfam | 70-187 (293) | Show / Hide |
Range on Protein: 246-348 Range on HMM: 70-187/293 Sequence Identity: 39% (47 aa) EDNSYLYMLLEFVSGG----EMFSHLR--RIGRF--SESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQHGYV----KVTDFGFA----KRVKGR ||....|| .|.. || . |.... | |.| || . .||. ||. . ||.| |..|||||||.|||..|.. |..|||.| .. EDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS- TWTLCGTPEYLAPEIIL-SK ..|.||||.|.|||.|. .. MTTFCGTPWYMAPEVIRGGQ |
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| S_TKc | AqueK013.AA | S_TKc | 194-348 | 23 | 6.7e-13 | 12.28 | SMART | 1-220 (231) | Show / Hide |
Range on Protein: 194-348
Range on HMM: 1-220/231
Sequence Identity: 23% (55 aa)
WDIVGI---------FLGIDNA--NIERIKSNNSNVDHRRKEIIIAWLRYGNATRQHLIEALKEDNSYLYMLLEFVSG--GEMFSHLRRIGR------FS
..|. . ...... | || . .| |.|| | . .|... . ..||| .|...| |..|..... || |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP
ESHSRFYASQIVLAFEYLHYLDIVYRDLKPENLLIDQHGYVKVTDFGFAKRVKGRTWTLCGTPEYLAPEII-----------------------------
| | |||. ||..| ||.| . |..|||||||.|.|. .|..|||.|... |.||||.|.|||..
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFPQM
-------------------------------LSK
. .
QMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ
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