Gene AqueK018 (A.queenslandica)

AqueK018

Species: A.queenslandica
Alias: AqueK018
External Links:
Annotation:

Classification

Group: AGC
Family: PKC
Subfamily: PKCh

Sequence

Name Sequence Type Origin Length Description Download
AqueK018.AA Protein None 689 None Fasta, JSON
AqueK018.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of AqueK018.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C2_PKD AqueK018.AA C2_PKD 12-163 24 1.2e-18 62.28 In-house 1-183 (183) Show / Hide 
Range on Protein: 12-163
Range on HMM: 1-183/183
Sequence Identity: 24% (44 aa)

TGLVSMTILEAQNLKSVT------LPGGHKLSNKDFDPYCVVDFDDIY----FGKTTHKTNTYCPVWNELVEEPVEDASRMQIALFHASTIPPNPFIAHV
.|  .  ...| .||         |  |   ..  .||||||. |.      .|.|| |. |  |.||.  .  |....  ||...|.  .|||...| .
MGFCRVRLCRADGLKPKMFQHWHNLTFGKPADCEAIDPYCVVHVDEKHENQHIGQTTQKKKTFYPEWNKCFDHHVYEGRHIQIVCMHNAIMPPNKMVAEC

QVPVSEIRL-----TKEDEFTLELEPEGSIRFRIQFQEKWGS----L----------AKKEFHVRSQVIKGHRG-AVR-RKIH
 . ....       .   .. ..||| | .   |.     ..    .            |||   .  .   || | | .|||
TMKLEDCIEMCKTNSGITHIWINLEPQGKVHVQIKWFNEDTDHKHHCDMIHPVPVLKMMKEFKRQRPGFNRRRGNAMRHAKIH
C2 AqueK018.AA C2 14-117 20 7.7e-17 63.19 SMART 1-92 (92) Show / Hide 
Range on Protein: 14-117
Range on HMM: 1-92/92
Sequence Identity: 20% (25 aa)

LVSMTILEAQNLKSVTLPGGHKLSNKDFDPYCVVDFDDIYFGKTTHKTNTY---CPVWNE---LVEEPVEDASRMQIALFHASTIPPNPFIAHVQVP---
..  .|.||.||.               |||..|        || ...||    .|||||    .. .| . . ... ...        || |...|   
TLTVHIIEARNLP---------------DPYVKVY-------KTKVVKNTLSGFNPVWNEWMETFYFDVHP-Q-LRFEVWDH------DFIGHCCIPPNN

-----------VSEIRLTKEDEFT
           .|.|.   ..   
PHWHQWDGCIHLSDIL-GYRH-WW
C2 AqueK018.AA C2 15-102 22 6.1e-11 39.79 Pfam 1-90 (90) Show / Hide 
Range on Protein: 15-102
Range on HMM: 1-90/90
Sequence Identity: 22% (21 aa)

VSMTILEAQNLKSVTLPGGHKLSNKDFDPYCVVDFDDIYF----GKTTHKTNTYCPVWNELVEEP--VEDASR-MQIALFHASTIPPNPFIAHVQ
.. ...||.||. .        .|   |||..| ...        ||  . || .|||||  . .  ..|  .  .. ...  ..  . || ...
LRVHVIEARNLPPMDW-----DKNGKSDPYVKVYLGGDPKDTQKYKTKVIKNTLNPVWNETFTFDVPPPDLQHTLRFTVWDWDRFGRDDFIGQCC
C1_1 AqueK018.AA C1_1 168-221 36 1.1e-18 72.21 Pfam 1-55 (55) Show / Hide 
Range on Protein: 168-221
Range on HMM: 1-55/55
Sequence Identity: 36% (20 aa)

HKFMAT-YLRQFTFCAHCRDFIWGLVNKQGYQCQVCSMVVHKRCHKSIITPCTGR
|.....  ..| |||.||..|.||.  .||..||.| ...|.|||.   . | . 
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 AqueK018.AA C1 168-218 30 1.8e-14 55.31 SMART 1-61 (61) Show / Hide 
Range on Protein: 168-218
Range on HMM: 1-61/61
Sequence Identity: 30% (19 aa)

HKFMATYLRQFTFCAHCRDFIWGLVN----KQGYQCQVCSMVVHKRCHKSIIT-------PC
|.....   . |.|.|||..|||.      .|||.|..| ...||.||. .         .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_1 AqueK018.AA C1_1 242-294 47 2.4e-22 85.38 Pfam 1-55 (55) Show / Hide 
Range on Protein: 242-294
Range on HMM: 1-55/55
Sequence Identity: 47% (26 aa)

HRFKVH-NYKRPTFCSHCGSLLWG-LYRQGLKCEACAINVHQRCEQFVAHSCGID
|....| |.|.||||.|||...|| |..||.||..|  |.|.|| ..|.  || .
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 AqueK018.AA C1 242-291 25 2.5e-16 61.47 SMART 1-61 (61) Show / Hide 
Range on Protein: 242-291
Range on HMM: 1-61/61
Sequence Identity: 25% (16 aa)

HRFKVHNYKRPTFCSHCGSLLWGLYRQ-----GLKCEACAINVHQRCEQFVAH-------SC
|... ... .||.|.||....||...|     |..|..|  ..|..|  .|.        .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
Kinase AqueK018.AA PKC 362-620 70 1.6e-204 669.1 In-house 1-262 (262) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-262/262
Sequence Identity: 70% (184 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDVI-QDDDIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFDED
|.|||||||||||||.||| |..|..||||||.|||| ||||.||..||||||||| .||.||..|.||||..||||||||||||||||.||..|.|.| 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEKDYGSSVDWWALGILMYEMMAGQPPF
.||||.||||.|| |||. |||||||||||||||..||.| |||||||||. .|. ||||||||||||||||....|| ||||||.|.|||||||||.||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

EADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQPGI--GERQIKIHAFF
....|||||..|..|...||.|||.|| ||. ||.||||..||||.|    ||. |. |.||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase AqueK018.AA AGC 362-620 33 2.6e-190 497.54 In-house 1-395 (395) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-395/395
Sequence Identity: 33% (135 aa)

FKFLKVLGKGSFGKVLLAEMK------NSDRVYAIKVLRKDV-IQDDD---IECVLTE------------KRVLALACR---------HPYLTS-MHSCF
|.||||.|||||||| |...|       ....||.|||.|.. |....   .|...||            ...|...           ||.... .|..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTEER--LFFVME----YVN-----GG-DLMFQIQ---RVRKFDEDRARFYSAE-------IILALLFLHN-VGIIYRD-LKLDNVLLDSDGHVKVADFG
|....  |.||||    |||     || .|....|   . ..|||.||||| ||       |.||| .||.  |||.|| ||..|.|||.|||.| .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MCKENIKDG--------------------------------------------------RLTSTFCG--TPDYIAPEILEEKDYGSSVDWWA--LGILMY
.|||...||                                                   .|.||||  ||.|.|||||    || ..|||.  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMMAGQPPFEADN----------EDELFEAIR------NDEVLYP----------VWLSREANSILRGFLTKNPARRLGCQPGI----GERQIKIHAFF
||..|.||| .||          ..|.|. |.      |..| .|          .|.| || ......|.|.|..||||...     |  .|| | .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AqueK018.AA Eta 362-620 72 2.7e-181 608.6 In-house 1-261 (261) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-261/261
Sequence Identity: 72% (188 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDVI-QDDDIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFDED
|.|.|||||||||||.|||.|. | |||||||.|||| ||||.|| .||||.|.|| .||.||..|.||||..|||||||||||||||||||| ||||| 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

RARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEKDYGSSVDWWALGILMYEMMAGQPPF
||||| ||...|| |||. |.|||||||||.||| .|| |.|||||||| | .|..|.||||||||||||||.| .|| ||||||.|.||||||.|||||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

EADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQP-GIGERQIKIHAFF
||||||.|||.| .|.|||||||..|| |||..|.|||| .||||     ||..|. |.||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase AqueK018.AA Alpha 362-620 65 4.1e-168 564.8 In-house 1-259 (259) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-259/259
Sequence Identity: 65% (170 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDV-IQDDDIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFDED
| ||.||||||||||.||| | .|  ||||.|.||| |||||.|| ..|||||||  . |.|..|||||||  ||.||||||||||||..||.| || | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

RARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEKDYGSSVDWWALGILMYEMMAGQPPF
 | || |||  .| |||. ||||||||||||.||..||.|.|||||||||. ..  | |||||||||||||     || |||||| |.|.||||||||||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

EADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQPGIGERQIKIHAFF
. . |||||.|| . .| ||  .|.|| .| .|||||.|..|||| |  ||. |. |.||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGP-DGEQDIREHPFF
Kinase AqueK018.AA Akt 362-620 50 8.8e-143 459.3 In-house 1-264 (264) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-264/264
Sequence Identity: 50% (134 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVY-AIKVLRKDVIQD-DDIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFDE
| |||||||||||||.|.. |.....| |.|||.||.|.. . .| ..||...|   |.||.....|  |||...|.|||.|.|||.| . .|| |.|.|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQ-HCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

DRARFYSAEIILALLFLHNVGIIYRD-LKLDNVLLDSDGHVKVADFGMCKEN-IKDGRLTSTFCGTPDYIAPEILEEKDYGSSVDWWA-LGILMYEMMAG
|||||| ||||||. .||. .||||| ||. |.|.|.|||....|||.|||| |||.  | |||||| |.|||||. .... .||||. ||..||||| |
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

QPPFEADNEDELFEAIRNDEVLYP--VWLSREANSILRGFLTKNPARRLGCQPGIGERQIKIHAFF
.||| ... ...|. | | .| .|   |.| |. ....| |.|.| .|||  |. . ..|| | .|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPN-DAQEIKRHPWF
Kinase AqueK018.AA Delta 362-620 59 1.7e-141 476.39 In-house 1-259 (259) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-259/259
Sequence Identity: 59% (155 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDVI-QDDDIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFDED
|.|.|||||||||||.|||.|. .. |||| |.|||. .|||.|| . |.|||||| .||.|. .   |||.| |||||||.||||||. || ...||| 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

RARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEKDYGSSVDWWALGILMYEMMAGQPPF
|||||..|||..| |||. ||||||||||||||| |||.|.|||||||||.     .||||||||||||||.. . |  |||||. |.|||||. || ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

EADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQPGIGERQIKIHAFF
. ..|||||..|.||.  ||.|...||...|.. . ..| .||| |    . .|..| ||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQ-YCPKGDIRQHCFF
Kinase AqueK018.AA Iota 362-620 57 4.2e-134 449.29 In-house 1-271 (271) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-271/271
Sequence Identity: 57% (156 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDVIQDD-DIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFDED
|. ..|.|.||. |||..|.|. .|.||.||..|....|| ||. | ||| |   |  ||.|  .||||||| |||||.|.|||||||| .|| ||  |.
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEE

RARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEKDYGSSVDWWALGILMYEMMAGQPPF
 ||||||||.||| |||. |||||||||||||||..||.|. |.|||||.|..| .|||||||| |||||||   ||| ||||||||.||.|||||  ||
HARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF

---------EADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQPGI--GERQIKIHAFF
         .   || ||  |   ..  |  ||  | ..|.||| |.|. ||||.| .  | . || |.||
DIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase AqueK018.AA SGK 362-620 42 7.1e-129 400.31 In-house 1-283 (283) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-283/283
Sequence Identity: 42% (122 aa)

FKFLKVLGKGSFGKVLLAEMKNS------------------DRVYAIKVLRKD-VI-------QDDDIECVLTEKRVLALACRHPYLTSMHSCFQTEERL
|.||||.||||||||.... |                    | .||.|||.|. .|       .      ...|. |.    .|| . . |  |||.. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FFVMEYVNGGDLMFQIQRVRKFDEDRARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEK
.|||.|||||.. . .|| ..| ||||||| |||..||  ||   ||||||| .|.|||..||..  ||| |||.||.   |.|||||| | |||.|  .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

DYGSSVDWWALGILMYEMMAGQPPFEADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQPGIGERQIKIHAFF
 .. .|||| ||...|||| | |||.  |  .... |.| .   |   | .| ... | |.|.|  |||   . .|  || | ||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFME--IKNHPFF
Kinase AqueK018.AA PKN 362-620 51 2e-112 379.82 In-house 1-260 (260) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-260/260
Sequence Identity: 51% (135 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRK-DVIQDDDIECVLTEKRVLALA--CRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFD
|... |||.| ||||||.. |.....||||.|.| |..  |..| ...|||... .   |||.| ....||||||  .|||||. ||||| .|     |.
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHE-DVFS

EDRARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEKDYGSSVDWWALGILMYEMMAGQP
| ||.||.| ..| | .||.  ||||||||||.||| .|.||.||||.|||..  |  ||||||||...|||.| .. |   |||| ||.|.|||. | .
EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGEC

PFEADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQPGIGERQIKIHAFF
||  |.|.|.|..| ||.| || .|| || .|.|  | ||| ||||      | .||...||
PFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAE-DIKMQPFF
Kinase AqueK018.AA AktR 362-620 42 2.7e-110 372.73 In-house 1-268 (268) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-268/268
Sequence Identity: 42% (114 aa)

FKFLKVLGKGSFGKVLLAEMK-NSDRVYAIKVLRK-DVIQDDDIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGGDLMFQIQRVRKFDE
|...|.|||| |||| |.. | .....||.|...| . |.   .. ..||. ...  |.|| .  .| ||||.| |||.|||. ||.| . ... .||.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DRARFYSAEIILALLFLHNV-GIIYRDLKLDNVLLDSDGHVKVADFGMCK-ENIK-DGRLTSTFCGTPDYIAPEILEE-KDYGSSVDWWALGILMYEMMA
..||||.|.|.||| .||.   ||||||| .| |||.||||| .|||. | .... .  .. .||||| |.|||.. . | .. ||||||.||. |||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GQPPFEADNEDELFEAIRNDE---VLYPVWLSREANSILR-GFLTKNPARRLG-CQPGIGERQIKIHAFF
|.|||...|  ..|. |.. .   . ||. .| .. ...  . | |||  |||   .|.   .|| | .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGW--EEIKSHPWF
Kinase AqueK018.AA S_TKc 362-620 35 4.7e-102 346.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDVIQDDDIECVLTEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNG--GDLMFQIQRVRK---
...|...|||.|||| ..  |...|..|||...         | .. | ..|    .||..  .. .||. ..|..||||..|  |||.  |.. ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEDRARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKDGRLTSTFCGTPDYIAPEILEEKDYGS-SVDWWALGILMYE
   |.| .|||| ..|..|| ..|. |||.|||| .|.|||.  |.|..|||....        .||||||.|.|||.|    ||  ..|||..|...||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MMAGQPPFEADNEDELFEAIRNDEVLYPVWLSREANSILRGFLTKNPARRLGCQPGIG-ERQIKIHAFF
|..|.|||.  .....|. |.          |.|| ...|. |.|.|..|...      |. ||.| .|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK018.AA Pkinase 362-620 27 7.4e-82 283.05 Pfam 1-293 (293) Show / Hide 
Range on Protein: 362-620
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDVIQD-DDIECVL-TEKRVLALACRHPYLTSMHSCFQTEERLFFVMEYVNGG----DLMFQIQ--R
.......|.||||.| ..  |.. ...|.|...|. . .  |.. .. .| ....   .||.   .. .|... .. .||||..||    ||.  |.  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

VRKF--DEDRARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHV----KVADFGMCKEN-IKDGRLTSTFCGTPDYIAPEILE-EKDYGSSVDWWA
 ..|  .|. ..||  .|. .| ..|. |||.||||..|.|.|..||.    |..||| .|   .  .. ..||||||.|.|||..   ..||..||.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGILMYEMMAGQPPFEAD------NEDELFEAIRNDEVLYPVWLS---------------------REANSILRGFLTKNPARRLGCQPGIGERQIKIHA
.|...|||. |.|||  .      ....... |.  .. .. . .                     .|. ..... |.|.|..|..       .||. | 
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT------AEQILQHP

FF
.|
WF
Kinase AqueK018.AA S_TK_X 621-684 36 8.9e-24 86.23 SMART 1-79 (79) Show / Hide 
Range on Protein: 621-684
Range on HMM: 1-79/79
Sequence Identity: 36% (29 aa)

RTIDWEKLEK--RQIPPPFKPQVR----GKRDFSNFDADFITEEPRLTPIESSALDNISQTE---------FKDFTYTN
| |||.||..  ..|.|||||...    . .| |||| .|  |.|.|||... ..... | |         | .||| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase AqueK018.AA TyrKc 362-609 20 2.3e-15 25.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 362-609
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

FKFLKVLGKGSFGKVLLAEMKNSDRVYAIKVLRKDVIQDDDIECVLTEKRVLALA-CRHPYLTSMHSCFQTE-------ERLFFVMEYVNGGDLMFQIQR
 ...|.|| | ||.| ....|   .  |.|.|..|      .|  . | |..     .|| .  .. .  ..       | |. ||||. .|||   ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

VRK-FDEDRARFYSAEIILALLFLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCKENIKD-------GRLTSTFCGTPD------YIAPEILEEKDYGS
 |. .  .    ..  |     .||  ..| |||   |.|......||..|||....   |          ...  .  .        ||| . .. . .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

SVDWWALGILMYEMMA-GQPPFEA-----DNEDELFEAIRNDEVLYPVWL---------SREANSILRGFLTKNPARRLG---CQPGI
  | |. |..|.|..  ||.| .       . .|..| ... . . .            . |  .| .     .|. |     .   .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK018.AA Pkinase_C 640-686 38 2.6e-12 46.59 Pfam 1-46 (46) Show / Hide 
Range on Protein: 640-686
Range on HMM: 1-46/46
Sequence Identity: 38% (18 aa)

QVRGKRDFSNFDADFITEEPRLTPIESSALDNISQTEFKDFTYTNAE
||....| |||| .|  | |..|| ... . .. | .| .|||.| .
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase AqueK018.AA Pkinase_Tyr 362-447 27 6.8e-12 40.91 Pfam 1-94 (270) Show / Hide 
Range on Protein: 362-447
Range on HMM: 1-94/270
Sequence Identity: 27% (26 aa)

FKFLKVLGKGSFGKVLLAEMK----NSDRVYAIKVLRKDVIQDDD--IECVLTEKRVLALACRHPYLTSMHSCFQ-TEER--LFFVMEYVNGGDL
 .|.|.||.|.||.| ....|    | .   |.|.| |.   ...  .|  . | ...   ..|| . ... .    .|   .. ||||. .|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase AqueK018.AA Pkinase_Tyr 475-508 35 2.8e-05 18.52 Pfam 126-159 (270) Show / Hide 
Range on Protein: 475-508
Range on HMM: 126-159/270
Sequence Identity: 35% (12 aa)

FLHNVGIIYRDLKLDNVLLDSDGHVKVADFGMCK
.|.. ..| |||   |.|......||..|||...
YLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase AqueK018.AA Pkinase_Tyr 528-580 25 0.07519 6.89 Pfam 182-237 (270) Show / Hide 
Range on Protein: 528-580
Range on HMM: 182-237/270
Sequence Identity: 25% (14 aa)

APEILEEKDYGSSVDWWALGILMYEMMA-GQPP-FEADNEDELFEAI-RNDEVLYP
||| . .. . .  | |. |.||.|..  |. | ..     |..|.| .. . . .
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC