Gene AqueK019 (A.queenslandica)

AqueK019

Species: A.queenslandica
Alias: AqueK019
External Links:
Annotation:

Classification

Group: AGC
Family: PKC
Subfamily: PKCi

Sequence

Name Sequence Type Origin Length Description Download
AqueK019.AA Protein None 161 None Fasta, JSON
AqueK019.kin_dom Protein Kinase Domain None 157 None Fasta, JSON

Protein domain

Protein domains of AqueK019.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK019.AA Iota 1-161 90 1.2e-128 430.88 In-house 17-177 (271) Show / Hide 
Range on Protein: 1-161
Range on HMM: 17-177/271
Sequence Identity: 90% (145 aa)

MVELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFL
|||.|.|.|||||||||||.| |.|||||||||||||||||||||||||||||||||||||||| |||||||||||| |.|||||||||||||.||||||
MVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEEHARFYSAEICLALNFL

HEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDY
||.|||||||||||||||..||||||||||||||.| |||||||||||||||||||||.||
HERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDY
Kinase AqueK019.AA PKC 1-161 65 1.7e-125 408.78 In-house 17-177 (262) Show / Hide 
Range on Protein: 1-161
Range on HMM: 17-177/262
Sequence Identity: 65% (105 aa)

MVELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFL
..|.|.|...||.||.||..... .|.....|||.|...|..||||..||.||||..|||||.| |||||||||.|. ||..|||||||.|||..||.||
LAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEEHARFYAAEIICALQFL

HEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDY
||||||||||||||||||..||||..|.|||||... |||||||||||.|||||||..|.|
HEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEY
Kinase AqueK019.AA AGC 2-161 32 1.3e-110 286.67 In-house 18-280 (395) Show / Hide 
Range on Protein: 2-161
Range on HMM: 18-280/395
Sequence Identity: 32% (87 aa)

VELK------QTKRIYAMKVIKKEL---VMDEEDIDWVQTE------------KHVFEQASN---------HPFLVG-LHSCFQTESR--LFFVIE----
|. |      .|...|||||.||.     ... ... ..||            ....|....         |||.|  ||..||....  |.|| |    
VRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPR

CVN-----GG-DLMFHMQ---RHRRLPEEHARFYSAE-------IALALNFLHE-KGIIYRD-LKLDNVLLDQDGHIKLTDYGMCKEGLRAG--------
 ||     || .|..|.|   . .|..||.|||| ||       |.||| .||. .|||.|| ||..|.|||.|||||||| |.|||| . |        
YVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQS

------------------------------------------DTTSTFCG--TPNYIAPEILRGQDY
                                          |.|.||||  ||.|.|||||    |
NMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----Y
Kinase AqueK019.AA Eta 1-161 58 2.7e-84 286.35 In-house 17-177 (261) Show / Hide 
Range on Protein: 1-161
Range on HMM: 17-177/261
Sequence Identity: 58% (94 aa)

MVELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFL
. |.|.|  .||.||.||. .. ..|..   ||| .   | .||||  ||.||||. |||||.| ||||||||..|| |.  |  |||| ||. .|| ||
LAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTCALMFL

HEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDY
|..|.|||||||||.|||..|| || |.||||||.  | ||.|||||| |||||||. ..|
HQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEY
Kinase AqueK019.AA Akt 5-161 50 9.8e-84 267.53 In-house 21-179 (264) Show / Hide 
Range on Protein: 5-161
Range on HMM: 21-179/264
Sequence Identity: 50% (81 aa)

KQTKRIY-AMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFLHEK
|.|...| ||||.||.   .   .  ..||. . .    |||.|.||  |||. .|.|| . .|||.| .|.|| || .|. |||| ||| ||. .||.|
KDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRARFYCAEIILAIEHLHSK

GIIYRD-LKLDNVLLDQDGHIKLTDYGMCKEG-LRAGDTTSTFCGTPNYIAPEILRGQDY
.||||| ||. |.|.|.||||.||| |.|||. .  .|.| |||||| |.||||| |...
NIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGH
Kinase AqueK019.AA SGK 1-161 42 1.4e-83 257.9 In-house 17-202 (283) Show / Hide 
Range on Protein: 1-161
Range on HMM: 17-202/283
Sequence Identity: 42% (79 aa)

MVELKQT------------------KRIYAMKVIKKELVM-------DEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHM
.|. |..                  . .|||||..|. .          .    ...|. |  .  .|||.|.||  |||.  |.|| . ||||.. .|.
QVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKLYFVMDYVNGGEMFYHL

QRHRRLPEEHARFYSAEIALALNFLHEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDY
|| ...||  |||| |||..||  ||.. ||||||| .|.||| .||..||| | ||||  . |||.|||||| | |||.||.| .
QREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPH
Kinase AqueK019.AA Alpha 3-161 57 7.7e-81 274.88 In-house 19-177 (259) Show / Hide 
Range on Protein: 3-161
Range on HMM: 19-177/259
Sequence Identity: 57% (91 aa)

ELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFLHE
| | |.  || |. ||  .  . |..   .|| |    .  |||| .||||||  ||.|| | |||||||.|.|.  .  | || || |||| .| ||||
ERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEPHAVFYAAEIAIGLFFLHE

KGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDY
|||||||||||||.|| .||||..|.|||||..  ..|| ||||||.||||||   | |
KGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPY
Kinase AqueK019.AA Delta 1-161 55 1.7e-76 260.43 In-house 17-177 (259) Show / Hide 
Range on Protein: 1-161
Range on HMM: 17-177/259
Sequence Identity: 55% (89 aa)

MVELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFL
..|||.... ||.| .||. |. ..|..    |..|   |..||||  |   |||.. ||||.| .||||||.|.|  .|  |. ||||..|| ..| ||
LAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEKRARFYACEIICGLQFL

HEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDY
|.||||||||||||||||.|||||. |.||||| .    ..||||||| ||||||..|| |
HKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKY
Kinase AqueK019.AA AktR 1-159 43 2.1e-64 220.25 In-house 17-180 (268) Show / Hide 
Range on Protein: 1-159
Range on HMM: 17-180/268
Sequence Identity: 43% (72 aa)

MVELK-QTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNF
.|. | .....||||.|||.   ... .. ..||. . |  .||||.| || ||||.. |||..| . ||.| .| .. ... || ||||.|.| ||| .
LVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEEQARFYFAQILLALEY

LHEK-GIIYRDLKLDNVLLDQDGHIKLTDYGMCK-EGLRAG-DTTSTFCGTPNYIAPEILRG-Q
||..  ||||||| .| |||.|||.|.||.|. | .. ..  ... .||||| |.|||...  .
LHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKK
Kinase AqueK019.AA RSK 5-161 42 4.8e-61 209.11 In-house 21-189 (278) Show / Hide 
Range on Protein: 5-161
Range on HMM: 21-189/278
Sequence Identity: 42% (72 aa)

KQTKRIYAMKVIKKELVMDEE-DIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRR---LPEEHARFYSAEIALALNFL
..|..||||||.||  ..  . |.  . ||  . |   .|||.| ||  ||||. |. . |...||.|  | |....   . |. |.|| |||.||. .|
HDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHL

HEKGIIYRDLKLDNVLLDQ---DGHIKLTDYGMCKEG-LRAGDTTSTFCGTPNYIAPEILR---GQD-Y
|..|||.||||..|.|.|.   .||||||| | ||.. .. .  | |||.| .|.|||.|.   .|  .
HQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGH
Kinase AqueK019.AA Pkinase 7-161 35 1.7e-48 172.26 Pfam 23-189 (293) Show / Hide 
Range on Protein: 7-161
Range on HMM: 23-189/293
Sequence Identity: 35% (60 aa)

TKRIYAMKVIKKELVMDEEDIDWVQ-TEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNGG----DLMFHMQ--RHRRL--PEEHARFYSAEIALAL
| .|.|.|.|||.   ...|.  .  .| ..     |||. | |. .|...... .| |...||    ||. ...  ||...  .|....||  .|. .|
TGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGL

NFLHEKGIIYRDLKLDNVLLDQDGHI----KLTDYGMCKEG-LRAGDTTSTFCGTPNYIAPEILR-GQDY
...|..|||.||||..|.|.|..|||    |..| | .|   .  .  ..||||||.|.|||..| ||.|
EYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY
Kinase AqueK019.AA S_TKc 1-161 25 5e-16 58.13 SMART 17-231 (231) Show / Hide 
Range on Protein: 1-161
Range on HMM: 17-231/231
Sequence Identity: 25% (62 aa)

MVELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIECVNG--GDLMFHMQRHRR------LPEEHARFYSAE
 .  | |.||.|.|.||          . .. |  . ..  .||..| |. .||. ..|..| |...|  |||. ......|      .|| ||||| ..
KCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQ

IALALNFLHEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQD--------------------------------
|..||...|..|||.|||| .|.|||.  |||..| |....        .||||||.|.|||.| | .                                
ICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKK

--------------------------------------Y
                                       
IGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK019.AA TyrKc 2-156 12 2e-06 -120.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-156
Range on HMM: 1-280/280
Sequence Identity: 12% (37 aa)

VELKQT------KRIY--------AMKVIKKELVMDEEDIDWVQTEKHVFEQA-SNHPFLVGLHSCFQTE-------SRLFFVIECVNGGDLMFHMQRHR
..|...       ..|        | |..|..       .     |  .  .   .|| .| |. .  ..         |. | | . .|||  . ..||
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

R-LPEEHARFYSAEIALALNFLHEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRA-----------------GD-------------TTS------
. |. ..   ..  ||   ..||.|..| |||   |.|.. ....| .| |.....                    |.              ..      
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

-------------TFCGTPNYI----------------------APEI-------------------------------------L
             |....| .                        |.                                      .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK019.AA Pkinase_Tyr 89-132 29 6e-06 20.75 Pfam 116-159 (270) Show / Hide 
Range on Protein: 89-132
Range on HMM: 116-159/270
Sequence Identity: 29% (13 aa)

YSAEIALALNFLHEKGIIYRDLKLDNVLLDQDGHIKLTDYGMCK
....|| ....|..|..| |||   |.|.. ....| .| |...
MCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR