Gene AqueK085 (A.queenslandica)
AqueK085
Species: A.queenslandica
Alias: AqueK085
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK085.AA | Protein | None | 332 | None | Fasta, JSON |
| AqueK085.kin_dom | Protein Kinase Domain | None | 179 | None | Fasta, JSON |
Protein domains of AqueK085.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK085.AA | Trbl | 97-294 | 42 | 8.8e-77 | 241.9 | In-house | 48-256 (256) | Show / Hide |
Range on Protein: 97-294 Range on HMM: 48-256/256 Sequence Identity: 42% (91 aa) IHEITDVSILSDRAFVFRPLS-------------HGDLHGCLRYHKVLTERVAAEYFRQIMVSIEAAHSNGLVLRDLKLKKFVFTDSNRFNLALSSLEDA | .|..| . ...|..| . |||.| | | | |. || |.|. . | .|.|||||||..||| | | | | ||||. IRRIHEVILGEQKAYIFFERTPQERDSTGGVTGVHGDMHSYVRHRKRLCEEEAARLFHQMCQAVAHCHQHGIVLRDLKLRRFVFKDEERTKLQLESLEDS VSVGKTIDSNDLLDNRNACPAYVAPEMLQP-GKYSGRAADMWSAGVILYTMLVGHYPFFDANPQLLFKKIRAGYFEFPHSMSFSVRSLIYSMLSYDPVQR . .. . | | .|||||.||.| . | ||| |||||| ||.|||||||.|||.| | .|| ||| | | | ..| ..|.||...| .| | C-IMTG--EDDSLWDKHGCPAYVSPEILCTQGSYSGKAADMWSLGVMLYTMLVGRYPFHDSEPCNLFTKIRRGQFCIPEHLSPKARCLIRCLLRREPSER PTAYAVSQHPWV || . ||| MTAQHILLHPWF |
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| Kinase | AqueK085.AA | CAMK | 117-294 | 23 | 7.4e-54 | 171.55 | In-house | 143-425 (425) | Show / Hide |
Range on Protein: 117-294
Range on HMM: 143-425/425
Sequence Identity: 23% (67 aa)
SHG----DLHGCLRYH---------------KVLTERVAAEYFRQIMVSIEAAHSNGLVLRDLKLKKFVFTDSNR---------------FNLALSSLED
| | || .. | . .||| |. ||||| .. ||.. | ||||. ..|.|. .|. ..
SGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGF
AVSVGKTIDS--------------------NDLLDNRNACPAYVA-PEMLQP-------------GKYSGRAADMWSAGVILYTMLVGHYPFFDA-----
| . . .. .... . .|.|.| ||.|. .| |...||||.|||||.||.|..|| .
ANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEI
--------NPQLLFKKIRAGYFEFPHS------------------------MSFSVRSLIYSMLSYDPVQRPTAYAVSQHPWV
|.. ||.||..| ..||.. | ....|| .|| .|| .|.|. . .|||.
CEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | AqueK085.AA | CAMKL | 203-294 | 36 | 2.5e-37 | 116.59 | In-house | 197-297 (297) | Show / Hide |
Range on Protein: 203-294 Range on HMM: 197-297/297 Sequence Identity: 36% (38 aa) PAYVAPEMLQP--GKYSGRAADMWSAGVILYTMLVGHYPFFDANPQ-------LLFKKIRAGYFEF-PH-SMSFSVRSLIYSMLSYDPVQRPTAYAVSQH |.| |||..| .| |...|.||.|||||.|..|..|| |.. . .|..||. | ... .. ..| ..|.|| .|| .| .|||. . .| PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH PWV ||. PWM |
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| Kinase | AqueK085.AA | MARK | 203-294 | 38 | 2.9e-36 | 116.16 | In-house | 169-262 (262) | Show / Hide |
Range on Protein: 203-294 Range on HMM: 169-262/262 Sequence Identity: 38% (36 aa) PAYVAPEMLQPGKYSGRAADMWSAGVILYTMLVGHYPFFDAN--PQLLFKKIRAGYFEFPHSMSFSVRSLIYSMLSYDPVQRPTAYAVSQHPWV |.| |||... .| |...|.|| ||.||.|..|..|| ... |.|||..| ...|. .| . |.|| ..| .| .|||. . .|||. PPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | AqueK085.AA | AMPK | 203-294 | 44 | 1.1e-34 | 100.49 | In-house | 163-254 (254) | Show / Hide |
Range on Protein: 203-294 Range on HMM: 163-254/254 Sequence Identity: 44% (41 aa) PAYVAPEMLQPGKYSGRAADMWSAGVILYTMLVGHYPFFDANPQLLFKKIRAGYFEFPHSMSFSVRSLIYSMLSYDPVQRPTAYAVSQHPWV | | |||| . .| |. | || ||||| || | || | | |.|||..| .. | .| ....|| .|| ||..| | .. .||| PCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | AqueK085.AA | MELK | 131-294 | 35 | 2.6e-33 | 110.97 | In-house | 94-254 (254) | Show / Hide |
Range on Protein: 131-294 Range on HMM: 94-254/254 Sequence Identity: 35% (58 aa) LTERVAAEYFRQIMVSIEAAHSNGLVLRDLKLKKFVFTDSNRFNLALSSLEDAVSVGKTIDSNDLLDNRNACPAYVAPEMLQPGKYSGRAADMWSAGVIL | | . .||||. .| || | |||| ..|.. .. | | |. | |. ||| |||..| .| | ||.|| |..| LEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHN--LQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILL YTMLVGHYPFFDANPQLLFKKIRAGYFEFPHSMSFSVRSLIYSMLSYDPVQRPTAYAVSQHPWV |....| || | | ....||| | .| |. .| . . |. || || .| . .|||| YVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
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| Kinase | AqueK085.AA | CAMK1 | 203-294 | 40 | 1.1e-32 | 92.26 | In-house | 177-276 (276) | Show / Hide |
Range on Protein: 203-294 Range on HMM: 177-276/276 Sequence Identity: 40% (41 aa) PAYVAPEMLQP---GKYSGRAADMWSAGVILYTMLVGHYPFFDAN-PQLLFKKIRAGYFEFPHS----MSFS-VRSLIYSMLSYDPVQRPTAYAVSQHPW | |||||.| | . | ||||.|||.|..|.|. ||.| | . ||.|| . .||| | . . .| || || .|.|.. . .||| PGYVAPEVLECKKDKPY-DKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPW V . I |
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| Kinase | AqueK085.AA | Ciliate-E2-Unclassified | 118-294 | 22 | 1.3e-29 | 99.91 | In-house | 105-352 (352) | Show / Hide |
Range on Protein: 118-294
Range on HMM: 105-352/352
Sequence Identity: 22% (55 aa)
HGDLHGCLR----------------YH-KVLTERVAA-----EYFRQIMVSIEAAHSNG-LVLRDLKLKKFVFTDSNR-FNLALSSLEDAVSVGKTIDS-
.|||. ... .. | .||. |. ||.|| . .| |... . ||.|. .|..... ... .. . . .. ...
GGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD
-----------NDLLDNRNACPAYV----APEMLQPGKYSGR---AADMWSAGVILYTMLVGHYPFFDANPQL----------------LFKKIRAG---
..... . | | |||.|| .|... ..|.|| ||||| || | |||.| | |...| ..
TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQ
YFEFPH-----SMSFSVRSLIY----SMLSYDPVQRPTAYAVSQHPWV
...||. |... .| .|| ..| .|.|. . .|||
FPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | AqueK085.AA | BRSK | 203-294 | 41 | 5.1e-26 | 85.62 | In-house | 163-254 (254) | Show / Hide |
Range on Protein: 203-294 Range on HMM: 163-254/254 Sequence Identity: 41% (38 aa) PAYVAPEMLQPGKYSGRAADMWSAGVILYTMLVGHYPFFDANPQLLFKKIRAGYFEFPHSMSFSVRSLIYSMLSYDPVQRPTAYAVSQHPWV | | || . || || ||.||.||||| .||| || | | | |.. | | || . .| |. || .| . . .|||. PHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY |
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| Kinase | AqueK085.AA | Pkinase | 203-294 | 30 | 1.5e-24 | 87.89 | Pfam | 175-293 (293) | Show / Hide |
Range on Protein: 203-294 Range on HMM: 175-293/293 Sequence Identity: 30% (36 aa) PAYVAPEMLQPGKYSGRAADMWSAGVILYTMLVGHYPFFDA------NPQLLFKKIRAGYFEFPHS---------------------MSFSVRSLIYSML | |.||| .. |.| |...||||.|.||| || |. || .. ... ....|. . ..|. . .| . ...|...| PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL SYDPVQRPTAYAVSQHPWV .|| .|||| . ||||. CKDPKKRPTAEQILQHPWF |
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| Kinase | AqueK085.AA | RSK | 204-294 | 33 | 6.6e-24 | 84.48 | In-house | 173-278 (278) | Show / Hide |
Range on Protein: 204-294 Range on HMM: 173-278/278 Sequence Identity: 33% (36 aa) AYVAPEMLQ---PGK-YSGRAADMWSAGVILYTMLVGHYPFFD---ANPQLLFKKIRAGY--FEFP--HSMSFSVRSLIYSMLSYDPVQRPT-----AYA .|.||||| ... .. .|.| || ||..|.||.|. || .|.. ..|.|. | ...| ...| ..|| || || .|.. | EYMAPEMLKRANQQGGHD-KACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEE VSQHPWV . |||| IKQHPWF |
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| S_TKc | AqueK085.AA | S_TKc | 2-294 | 21 | 6.3e-17 | 63.47 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 2-294
Range on HMM: 1-231/231
Sequence Identity: 21% (68 aa)
YTILHEI--------------QTSSHHVGKINRVDETPPEQDDLTTTPLSPASFKIAGRYKFEAPPVFLTPNSNVPCVDTMTGALLASQAYPLGRFMEVC
|.|| .| | . || . |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------------------------------EHIRREIQ
HLLNLTLPGIHEITDVSILSDRAFVFRPLSHG---DLHGCLRYHKV------LTERVAAEYFRQIMVSIEAAHSNGLVLRDLKLKKFVFTDSNRFNLALS
| . | | . || |. ... . | ||. .. .. ..| .|. |..|| .| ||.| . |||| ... .. ..
ILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKIC
SLEDAVSVGKTIDSNDLLDNRNACPAYVAPEMLQPGKYSGRAADMWSAGVILYTMLVGHYPFFDANPQLLFKKIRAGYFEFPHSMSFSVRSLIYSMLSYD
| . . | |.|||.| .|.....|.|| |.||| ||.| || ..|..||||. | .....| .| .|
DFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKD
PVQRPTAYAVSQ-------HPWV
| .|||| . | |||.
PEKRPTA-EALQDEWDIKCHPWF
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| Kinase | AqueK085.AA | Pkinase | 118-162 | 30 | 8e-06 | 21.67 | Pfam | 84-136 (293) | Show / Hide |
Range on Protein: 118-162 Range on HMM: 84-136/293 Sequence Identity: 30% (16 aa) HG----DLHGCLR--YHKVL--TERVAAEYFRQIMVSIEAAHSNGLVLRDLKL .| ||. .. .|... .|... |..|| .| ||.| . ||||. GGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKP |
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| Kinase | AqueK085.AA | CAMKL | 119-162 | 34 | 3.6e-05 | 12.3 | In-house | 106-155 (297) | Show / Hide |
Range on Protein: 119-162 Range on HMM: 106-155/297 Sequence Identity: 34% (17 aa) GD--LHGCLRYH----KVLTERVAAEYFRQIMVSIEAAHSNGLVLRDLKL |. |. .. | . ..|. | |||||. .. ||.| | ||.|. GEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKP |
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| Kinase | AqueK085.AA | MARK | 117-162 | 35 | 7.4e-05 | 12.0 | In-house | 85-132 (262) | Show / Hide |
Range on Protein: 117-162 Range on HMM: 85-132/262 Sequence Identity: 35% (17 aa) SHGDLHGCLRYH--KVLTERVAAEYFRQIMVSIEAAHSNGLVLRDLKL | |.|..... | |.|. | .|||| .. ||.. | ||.|. SGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKP |
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| Kinase | AqueK085.AA | RSK | 119-162 | 31 | 0.000199 | 12.52 | In-house | 86-132 (278) | Show / Hide |
Range on Protein: 119-162 Range on HMM: 86-132/278 Sequence Identity: 31% (15 aa) GDLHGCLRYHKV---LTERVAAEYFRQIMVSIEAAHSNGLVLRDLKL |.| |. .| ..|. |..|...| . .| |. | . ||||. GELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKP |
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| Kinase | AqueK085.AA | AMPK | 131-162 | 43 | 0.000327 | 8.47 | In-house | 97-128 (254) | Show / Hide |
Range on Protein: 131-162 Range on HMM: 97-128/254 Sequence Identity: 43% (14 aa) LTERVAAEYFRQIMVSIEAAHSNGLVLRDLKL |.|| |. .| || .| | .. | ||||. LQEREACRFFQQIISGVEYCHRHMIVHRDLKP |
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| Kinase | AqueK085.AA | BRSK | 131-161 | 41 | 0.009256 | 5.21 | In-house | 97-127 (254) | Show / Hide |
Range on Protein: 131-161 Range on HMM: 97-127/254 Sequence Identity: 41% (13 aa) LTERVAAEYFRQIMVSIEAAHSNGLVLRDLK || . | .|||| .. || |||| LTPKEARKFFRQIISALDFCHSHNICHRDLK |
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