AqueK153

Species: A.queenslandica
Alias: AqueK153
External Links:
Annotation:

Classification

Group: Other
Family: CAMKK
Subfamily: CAMKK-Meta

Sequence

Name Sequence Type Origin Length Description Download
AqueK153.AA Protein None 538 None Fasta, JSON
AqueK153.kin_dom Protein Kinase Domain None 207 None Fasta, JSON

Protein domain

Protein domains of AqueK153.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK153.AA Meta 242-417 50 5.4e-103 298.34 In-house 110-287 (287) Show / Hide
Range on Protein: 242-417
Range on HMM: 110-287/287
Sequence Identity: 50% (92 aa)

PVMEDIDVDNAVSEDKAREYFIDLILGLEYVHSCKVVHRDIKPENLLLDDYDRIKIADFGVSENWSSEKQDADLRSS---AGTPAFTAPETLDGVRSV-F
|||| .  ||  |||.|. || |...|||| |  |..||||||.||||.|   .||||||||     |  || ....   |||||| |||..   .   .
PVME-VPCDNPLSEDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLLLNDDGHVKIADFGVSNEF--EGDDA-FLCNGSTAGTPAFMAPEACSEEQNHFY

GGRALDVWAAGVTLYCLVYGRVPFVG--RSIPELHEKIISQEIKFPDDITVSEELKDLLIRLLNKEPSGRITIPEIRKHKWF
.|||||||| ||||||.|.|..||.    .|. ||.|| .....||... .||.|||.  |.| |.|  ||.||||  |.| 
CGRALDVWAMGVTLYCFVFGQCPFIDKTNYIMCLHDKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV

Kinase AqueK153.AA CAMKK 253-417 33 1.2e-83 265.26 In-house 152-396 (396) Show / Hide
Range on Protein: 253-417
Range on HMM: 152-396/396
Sequence Identity: 33% (82 aa)

VSEDK---------------------AREYFIDLILGLEYVH-SCK-------------------VVHRDIKPENLLLDDYD---RIKIADFGVSENWSS
.||..                     |..|| | |.|||| | . |                   ..||||||.|.|.|. .   ..||||||||   ..
MSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEG

EKQD-AD--------LRSSAGTPAFTAPETLDG-VR------------SVFGGRALDVWAAGVTLYCLVYGRVPFVGRSIPELHE---KIISQEIKFPD-
..|.  .        | . ||||||.||| ..                 .. |.|.|.||.||||||.|.|..||.......||.   ||. ..||||. 
QDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPEN

----------DITVSEELKDLLIRLLNKEPSGRITIPEIRKHKWF
          .  .||.||||. |.|.|.|  |||||.| .|.|.
KEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV

Kinase AqueK153.AA AGC 254-417 25 2.2e-63 161.76 In-house 144-395 (395) Show / Hide
Range on Protein: 254-417
Range on HMM: 144-395/395
Sequence Identity: 25% (65 aa)

SEDKAREYFID-------LILGLEYVHS-CKVVHRD-IKPENLLLDDYDRIKIADFGVSEN--------------------------------------W
.|. || |.         ..|.||| ||  ...||| .||||.|||.   ||..||| .                                        |
DEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNW

SSEK----------QDADLRSSAG--TPAFTAPETLDGVRSVFGGRALDVWA--AGVTLYCLVYGRVPFVGRS----------IPELHEKII------SQ
 ...          ...   .  |  || . ||| |        |.| | |.   |. .| ...|. || | .            |...||.      ..
QRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINW

EIKFP--------DDITVSEELKDLLIRLLNKEPSGRIT----------IPEIRKHKWF
..|||        .|  .|.|.|||. .||.|.|. |..          . ||..|.||
KVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase AqueK153.AA LKB 258-417 38 1.2e-61 181.73 In-house 106-265 (265) Show / Hide
Range on Protein: 258-417
Range on HMM: 106-265/265
Sequence Identity: 38% (61 aa)

AREYFIDLILGLEYVHSCKVVHRDIKPENLLLDDYDRIKIADFGVSENWSSEKQDADLRSSAGTPAFTAPETLDGVRSVFGGRALDVWAAGVTLYCLVYG
|  ||..|. |.|| ||..|||.|||| ||||     .|| |||| |  .  ..|  .. | |.|||  ||   |   .| |   |.|..||||| .. |
AHFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRDDCCTTSQGSPAFQPPECANGNHDTFSGFKVDIWSMGVTLYNMTTG

RVPFVGRSIPELHEKIISQEIKFPDDITVSEELKDLLIRLLNKEPSGRITIPEIRKHKWF
. || |  .  | | |   ....|  . .  .| .|.  .| .... | .. .|..| ||
KYPFEGDNMYKLFENIGKCQWEMPCWYDCDKDLQNLIKGMLQYDHNKRFSCHQIMHHPWF

Kinase AqueK153.AA CAMKK-Unclassified 254-417 30 2.1e-61 198.69 In-house 176-392 (392) Show / Hide
Range on Protein: 254-417
Range on HMM: 176-392/392
Sequence Identity: 30% (67 aa)

SEDKAREYFIDLILGLEYVHSCK---------------------VVHRDIKPENLLLDDYDR-----IKIADFGVSENWSSEKQDADLRSSAGTPAFTAP
.|.....|| . ..|| | |  .                     ..||||||.|.|.|. |.     .||||||.|   ..|.|   | . |||..|.||
HEQYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKK-LKNNAGTYCFMAP

ETLDGVRSVFGGRALD---------------------------VWAAGVTLYCLVYGRVPFVGRSIPELHE-KIISQEIKFPD--DITVSEELKDLLIRL
| ..  ...|... .|                           .|..|||.||.||...|| ... .|| . .|.  ||.||       |.|.|||. ..
EFWS--KENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKM

LNKEPSGRITIPEIRKHKWF
..| |  ||||  . .| ||
CDKNPKKRITIDQMLVHPWF

Kinase AqueK153.AA CAMK 253-417 26 6.6e-61 194.68 In-house 176-425 (425) Show / Hide
Range on Protein: 253-417
Range on HMM: 176-425/425
Sequence Identity: 26% (65 aa)

VSEDKAREYFIDLILGLEYVHSCKVVHRDIKPENLLLDDYD-----------------RIKIADFGVSENWSSEK---------------------QDAD
..|. || ||  .. ...| ||...||||.||||.|||| .                  |||.||| .    . .                     ..  
FTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQK

LRSSAGTPAFTA-PETLDGVR-----------SVFGGRALDVWAAGVTLYCLVYGRVPFVGR-------------SIPELHEKIISQEIKFPDDI-----
.. . |||.. | || | | .               |.. |.|..|| || .. |. || |              ...||.|||.. .  ||..      
MKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPIS

-----------------TVSEELKDLLIRLLNKEPSGRITIPEIRKHKWF
                 .||.| |||. ..|...|. |.|| .. .|.|.
CNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase AqueK153.AA CAMKL 254-417 34 1.2e-59 189.01 In-house 125-297 (297) Show / Hide
Range on Protein: 254-417
Range on HMM: 125-297/297
Sequence Identity: 34% (61 aa)

SEDKAREYFIDLILGLEYVHSCKVVHRDIKPENLLLDDYD--RIKIADFGVSENWSS--EKQDADLRSSAGTPAFTAPETLDGVRSVFGGRALDVWAAGV
.|. || ||  .. ...| ||...|||||||||.|||. .   |||.||| |        . .  |. . |.|.. ||| . |    . |.. |.|..||
PEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGV

TLYCLVYGRVPFVGRSIP-------ELHEKIISQEIKFPDDITVSEELKDLLIRLLNKEPSGRITIPEIRKHKWF
.|| .|.|..|| . ...       .|..||...  ..|  . || ...||. ..|.. |. |.|| .|..|.|.
ILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase AqueK153.AA AMPK 251-417 39 7.1e-55 161.37 In-house 95-254 (254) Show / Hide
Range on Protein: 251-417
Range on HMM: 95-254/254
Sequence Identity: 39% (66 aa)

NAVSEDKAREYFIDLILGLEYVHSCKVVHRDIKPENLLLDDYDRIKIADFGVSENWSSEKQDADLRSSAGTPAFTAPETLDGVRSVFGGRALDVWAAGVT
. ..|. |. .|   | |.||.|  ..|||| ||||||||.  .|||.||| |   .  ..   |. . | |   |||.  | .    |.  |.|  || 
GRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEF---LKTACGSPCYAAPEMISGKL--YCGPEVDIWSCGVI

LYCLVYGRVPFVGRSIPELHEKIISQEIKFPDDITVSEELKDLLIRLLNKEPSGRITIPEIRKHKWF
|| .. |. ||   ..|.|  ||...| . |..  .|.| |||. ..|.. |  |||| .||.|.||
LYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKF--LSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase AqueK153.AA Ciliate-E2 254-417 25 4.8e-48 163.0 In-house 143-365 (365) Show / Hide
Range on Protein: 254-417
Range on HMM: 143-365/365
Sequence Identity: 25% (60 aa)

SEDKAREYFIDLIL---------------GLEYVHSCK-VVHRDIKPENLLLDDYDRIKIADFGVSE----------------NWSSEKQDADLRSS---
.| ......  ..                .||| || . ..||||||||.|.     |||.||| |                 ..   |.| .  ..   
TEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD

-----------AGTPAFTAPETLDGVR------SVFGGRALDVWAAGVTLYCLVYGRVPFVGRSIPELHEKIISQEIKFP----------------DDIT
           .||| . ||| | |        .   . . |.|..||.||....|. ||         ..|. ..|.||                .   
QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKK

VSEELKDLLIR----LLNKEPSGRIT-IPEIRKHKWF
.|.| |||. .    .|.|.|. ||| . .| .|.||
WSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase AqueK153.AA Ciliate-E2-Unclassified 250-417 28 9e-47 160.26 In-house 132-352 (352) Show / Hide
Range on Protein: 250-417
Range on HMM: 132-352/352
Sequence Identity: 28% (63 aa)

DNAVSEDKAR-----EYFIDLILGLEYVHSCK-VVHRDIKPENLLLDDYD---RIKIADFGVS-ENWSSEKQDAD-------------LRSSAGTPAFT-
.. ..| .|.      ||  ...|||| |. . ..||||||||.|.|.     .|||.||| | .. .....| .             . . .||| .  
RKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMP

---APETLDG-VRS--VFGGRALDVWAAGVTLYCLVYGRVPFVGRSIPE----------------LHEKIISQEIKFP------DDITVSEELKDLLI--
   ||| |.|   .   .   . |.|. || ||....|. || ...  .                |...|. ..|.||      .. ..|.| ||..   
QYTAPEVLQGQNYDHSKA--YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDL

--RLLNKEPSGRITIPEIRKHKWF
  ..|.| |. |||...| .| ||
LQKMLKKNPNKRITFEQILNHPWF

Kinase AqueK153.AA Pkinase 250-417 28 2.5e-46 164.91 Pfam 100-293 (293) Show / Hide
Range on Protein: 250-417
Range on HMM: 100-293/293
Sequence Identity: 28% (58 aa)

DNAV--SEDKAREYFIDLILGLEYVHSCKVVHRDIKPENLLLDDYDRI----KIADFGVSENWSSEKQDADLRSSAGTPAFTAPETLDGVR-SVFGGRAL
....  ||. .. |.  .. |||| ||....|||.||||.|.|. . |    ||.|||...  . .  .  . . .||| . |||    .| .   |.. 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV---IRGGQYYGPKV

DVWAAGVTLYCLVYGRVPFVGR------SIPELHEKIISQEIKFPDDITVS-------------------EELKDLLIRLLNKEPSGRITIPEIRKHKWF
|.|..|..||... || || |.      .  .....| . ...|. . . |                   ||.||.. ..|.| |. |.|...| .|.||
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF





S_TKc AqueK153.AA S_TKc 238-417 23 5.3e-21 77.02 SMART 19-231 (231) Show / Hide
Range on Protein: 238-417
Range on HMM: 19-231/231
Sequence Identity: 23% (57 aa)

VDTR----------------------------------------------------PVMEDIDVDNA------VSEDKAREYFIDLILGLEYVHSCKVVH
....                                                     ... |.  .        .|  || |.  ....||| || ...|
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIH

RDIKPENLLLDDYDRIKIADFGVSENWSSEKQDADLRSSAGTPAFTAPETLDGVRSVFGGRALDVWAAGVTLYCLVYGRVPFVGRSIPELHEKIISQEIK
||.||||.|||.  .|||.|||..            ..  ||| . ||| |      .|... |.|. |..|| ...|. ||    . .. .||      
RDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----

FPDDITVSEELKDLLIRLLNKEPSGRITIPEIRK-------HKWF
       |.|.||.. ..|.|.|. |.|. |. .       | ||
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

TyrKc AqueK153.AA TyrKc 237-417 15 4e-06 -123.37 SMART 1-280 (280) Show / Hide
Range on Protein: 237-417
Range on HMM: 1-280/280
Sequence Identity: 15% (43 aa)

XVDTRP------------------------------------VMEDI---------------DV---------------------------DNA--VSED
 .  .                                     .|  .               .                            ..   .. .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

KAREYFIDLILGLEYVHSCKVVHRDIKPENLLLDDYDRIKIADFGVSENWSSE----KQDADLRSSA--GTP-----AFTAPETLDGVRSVFGGRALDVW
.  .. ..   | || || ...|||.   | |...  ..||.||| | .. ..      .   |..   |.        .|||..    ..|   . |||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF-TTKSDVW

AAGVTLYCLV-YGRVPFVG-----RSIPELHEKIISQEIKFPDDI-------TVSEELKDLLIRLLNKEPSGRITIPEIRKHKWF
. ||... .  ||  |  |      |  |..|.. . .   . .        . ..|. ..  .  . .|. | |  ||  |. |
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF