Gene AqueK177 (A.queenslandica)

AqueK177

Species: A.queenslandica
Alias: AqueK177
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK10

Sequence

Name Sequence Type Origin Length Description Download
AqueK177.AA Protein None 910 None Fasta, JSON
AqueK177.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of AqueK177.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK177.AA NEK10 373-643 49 1.3e-129 429.55 In-house 1-279 (279) Show / Hide 
Range on Protein: 373-643
Range on HMM: 1-279/279
Sequence Identity: 49% (139 aa)

YEVLELLGTGAYGSVYKVRKGPPRGSN------FYALKEIQMTHPSLAGCSSLEERNGSIGKIMSEVSMIHKKLRHPNIVQYFKCFEE--SHHLYIEMSL
|||.. |||||.|.||||||    ...      . |.||| |. |  |      ||. ||. . ||.. |  ..|||||| |.. | |   | .|| | |
YEVYDHLGTGAFGCVYKVRKK--AQQHSENPAKLLAMKEIFMHNP--AFGKNDKERDKSIEDMISELKIIKEQMRHPNIVRYYRTFVEPQNHRMYIVMEL

IEGTPLSEFISSMKEKKTFFSEKRIWTIFSQMIRALRYIHEDKGITHRDLKPANMILGEHDKLTITDFGLAKDQK-DFSVMKSIVGTVVYWCPEIVESKE
||| || | ..|||||.  |.|.||| .| ||. |||| |  | | ||||.| |  .|. |. ||||||||| .  | | |.|.|||..| ||||| |. 
IEGCPLYEHFNSMKEKHHHFEEERIWHMFIQMCLALRYLHKEKQIVHRDLTPNNIMMGDKDRVTITDFGLAKQKQPDPSKMTSVVGTILYSCPEIVQSEP

YDKKADIWAAGCVLYEMAALQPPFYATNLLSLAKKIAEGKFETAPLDKYSAQVSDVITKCLTIDPTLRPNSVQIGG---MIAE
|  |||.||.||.||.|. |||||| ||.|.|| || | ...  .   .| .| ..||.||| ||  ||  |.. .   ||  
YGEKADVWAFGCCLYQMCTLQPPFYSTNMLTLAMKIVEHFYDPVNEGMWSDDVRFTITRCLTPDPEARPDIVKVSSVLRMIQD
Kinase AqueK177.AA NEK 438-633 38 8.9e-80 271.35 In-house 59-276 (286) Show / Hide 
Range on Protein: 438-633
Range on HMM: 59-276/286
Sequence Identity: 38% (84 aa)

KKLRHPNIVQYFKCFEE--SHHLYIEMSLIE-GTPLSEFISSMKEKKT---FFSEKRIWTIFSQMIRALRYIHEDK----GITHRDLKPANMILGEHDK-
|.|.||||| |. .|.|  ...|.|.|   | |  |...|.| |..|    .|.|. || .| ||. ||.|.|. |     | |||.||.|  |   .. 
KQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNND

---LTITDFGLAKDQK-DFSVMKS-IVGTVVYWCPEIVESKEYDKKADIWAAGCVLYEMAALQP--PFYAT--NLLSLAKKIAEG-KFETAPLDK-YSAQ
   . | |||..| .. . .  ..  |||  | .||....| |. |.|||. |||||||..|.|  ||.|.  |..||..|| .| ...  |    || .
YHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQD

VSDVITKCLTIDPTLRPN
 ...|...|. ||..||.
LQNLISQMLQKDPEQRPS
Kinase AqueK177.AA S_TKc 373-647 31 1.3e-71 245.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 373-647
Range on HMM: 1-231/231
Sequence Identity: 31% (88 aa)

YEVLELLGTGAYGSVYKVRKGPPRGSNFYALKEIQMTHPSLAGCSSLEERNGSIGKIMSEVSMIHKKLRHPNIVQYFKCFEESHHLYIEMSLIEG--TPL
||.|...| ||.|.|||.|.        .|.|.|                     .|..|... .|  .|||||... .|.. .|||. | ...|    |
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-------------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDL

SEFISSMKEKKTF--FSEKRIWTIFSQMIRALRYIHEDKGITHRDLKPANMILGEHDKLTITDFGLAKDQKDFSVMKSIVGTVVYWCPEIVESKEYDK-K
 ..| ... ...   |.| ... .. |...|| |.|.  || ||||||.|  | |   . |.|||||.        ....||  |  ||..    |.| |
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCK

ADIWAAGCVLYEMAALQPPFYATNLLSLAKKIAEGKFETAPLDKYSAQVSDVITKCLTIDPTLRPNSVQIGG---MIAEHLMV
.|.|. ||.||||.. .|||.  ..  . |||             | .. | | |||. ||. ||   ..      |. |  .
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK177.AA Pkinase 373-641 28 5.3e-59 207.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 373-641
Range on HMM: 1-293/293
Sequence Identity: 28% (88 aa)

YEVLELLGTGAYGSVYKVRKGPPRGSN-FYALKEIQMTHPSLAGCSSLEERNGSIGKIMSEVSMIHKKLRHPNIVQYFKCFEESHHLYIEMSLIEGT---
|.... .| |..|.||| ..   .|..  .|.|.|   | .   . ..  .        ||.  |.|.|.|||||... .||.. |.|. | . ||.   
YHIGRKIGSGSFGCVYKCHH---KGTGKIVAVKIIKKRHEKSWKDQTHRRL--------SEI-QIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYV

-PLSEFISSMKEKKTFF--SEKRIWTIFSQMIRALRYIHEDKGITHRDLKPANMILGEHDKL----TITDFGLAKD--QKDFSVMKSIVGTVVYWCPEIV
  |...||   .... |  ||. .  .. |..|.| |.|. .|| ||||||.|  . ... .     |.||||||       | |....||  |  ||..
MDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVI

E-SKEYDKKADIWAAGCVLYEMAALQPPFYAT------NLLSLAKKIAEGKFETAPLDKYS-------------------AQVSDVITKCLTIDPTLRPN
  ...|..|.|.|..||.||||.  .|||.        . . . ..| .....     ..|                       |.|..||. ||. ||.
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

SVQIGGM--I
  ||     .
AEQILQHPWF
Kinase AqueK177.AA CAMK 378-637 20 3e-55 176.11 In-house 1-419 (425) Show / Hide 
Range on Protein: 378-637
Range on HMM: 1-419/425
Sequence Identity: 20% (84 aa)

LLGTGAYGSVYKVRKGPPRGSNF----------YALKEIQM----------------THPSLAGCSSLEERNGSIGKIMSEVSMIHK------KLRHPNI
 ||.|..| |....     |             .| | |                     | ..... ..|  .  ....|...  |      ||.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYFKCFEESHH-------------------LYIEM---SLIEGT----PLSEFISSMKEKK-----------TFFSEKRIWTIFSQMIRALRYIHEDKG
.. .  .| .|.                   .|. |    ...|      | ..| . . .              |.|.   ..| |.. |..|.|. . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

ITHRDLKPANMILGEHD-----------------KLTITDFGLAKDQKD------------------------FSVMKSIVGTVVYWC-PEIVESKE---
| |||||| |  | ...                 .. |.|||.|.  ..                           ||  .||  | . ||....|    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YDKKADIWAAGCVLYEMAALQPPFYAT-------------NLLSLAKKIAEGKFETAP--------------LDKYSAQ--------VS
           |..|.|.|..|..|| |    ||||.              |.  | .|| .||..  |               |. | .        . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DVITKCLTIDPTLRPNSVQI
| | |.|. ||. |..  |.
DLIRKMLQVDPEKRMTIEQC
Kinase AqueK177.AA NEK8 429-632 34 7.9e-54 151.99 In-house 47-267 (278) Show / Hide 
Range on Protein: 429-632
Range on HMM: 47-267/278
Sequence Identity: 34% (77 aa)

IMSEVSMIHKKLRHPNIVQYFKCFEESHHLYIEMSLIEGTPLSEFISSMKEKKTFFSEK----------------RIWTIFSQMIRALRYIHEDKGITHR
...|..   ..| ||||. |.  |.|   | |||   .|  | ..|.. . |. |. |.                 |   | ||  |....|. ..| ||
AQNEIQVL-SMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKL-FEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQ-HNILHR

DLKPANMILGEH-DKLTITDFGLAKDQKDFSVMK-S--IVGTVVYWCPEIVESKEYDKKADIWAAGCVLYEMAALQPPFYATNLLSLAKKIAEG-KFETA
|||..|  .  |   . | |||..|   . . |  .  .|||  |  ||..|.|.|. | |.|| |||||||. |   | |.||. |  ||  . ..|  
DLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPI

PLDKYSAQVSDVITKCLTIDPTLRP
. |.||. .  ... ||  ||  ||
S-DHYSNEMRMLVHNCLQQDPEQRP
Kinase AqueK177.AA STE 373-636 22 9.6e-53 181.55 In-house 1-350 (359) Show / Hide 
Range on Protein: 373-636
Range on HMM: 1-350/359
Sequence Identity: 22% (83 aa)

YEVLELLGTGAYGSVYKVRKGP-----PRGSN--------FYALKEIQMTHPS----LAGCSSLEERNGS--------IGKIMSEVSMIHKKLR-HPNIV
.| .| .| ||.|.||| ..       . | .        ..| |.. . . .    .      |. . .        . .|. |... .|    |||||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDEN----Q-EN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIV

QYFKCFEES-------HHLYIEMSLIEGTPLSEFISSMKEKK----------TFFSEKRIWTIFSQMIRA-LRYIHEDKGITHRDLKPANMILGEHDKLT
.|. |..         ..|.| | ...|  |...| . ....          ..|.|. | .|  | ... | |.|. . | |||.||||  |       
KYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VK

ITDFGLAKDQKD-----------------FSVMKSIVGTVVYWCPEIVES------KEYDKKADIWAAGCVLYEMAALQPPF---YAT-NLLSLAKKIAE
..|||...   |                  .  ...|||  .  ||...       |.|| |.|||  ||.. |||  .||.   . . ...  ..... 
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

GK---------FETAPLD--------------------KYSAQVSDVITKCLTIDPTLRPNSVQ
.          ..  ||                     |.|    | | |||..||  ||.. |
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase AqueK177.AA ULK 373-631 26 8.8e-51 175.03 In-house 1-317 (329) Show / Hide 
Range on Protein: 373-631
Range on HMM: 1-317/329
Sequence Identity: 26% (86 aa)

YEVLELLGTGAYGSVYKVR---KGPPRGSN-FYALKEIQ---MTHPSLA--GCSSLEERNGSIGKIMSEVSMIHKKL-------RHPNIVQYFKCFEESH
|.. . || |..| ||| |   .. .  .|  .| | |.   |   .    |       .  .  ...|.  ..|         .|||||.....||.|.
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEG-------QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSN

H--LYIEMSLIEGTPLSEFISSMKE------KKTFFSEKRIWTIFSQMIRALRYIHEDKGITHRDLKPANMILGEHDKLT------------ITDFGLAK
|  .|| | . .|  |...|.  |.      .| ..||. .  .| | . .....|. ..| |||.||.|  . ...  |            |.|||.||
HNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAK

D-QKD---FSVMKSIV------GTVVYWCPEIVE----SKEYD-KKADIWAAGCVLYEMAALQPPFYATNLLSLAKKIAEGKFE----------TAPLD-
  ..|     .|.. |      ||  | .|.|..     |.|. .|.|||  ||..|||   .|||||    .. ..| .  ..          . ||. 
HVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQF

-------KYSAQVSDVITKCLTIDPTLR
       . | .. | | ..|..|.. |
PKDGNDPQISPECKDLIRRMLQYDEKDR
Kinase AqueK177.AA Ciliate-E2-Unclassified 373-637 22 1.2e-49 170.41 In-house 1-346 (352) Show / Hide 
Range on Protein: 373-637
Range on HMM: 1-346/352
Sequence Identity: 22% (79 aa)

YEVLELLGTGAYGSVYKVRKGPPRGSNFYALKEIQMTHPSLAGCSS------------LEERNGSIGK----IMSEVSMIHKKLRHPNIVQYFKCFEESH
|.... .|.|..|.|||...   .  ..|. ... . . . . ..             ........ .    || .   | . . ||.|| .| ||.   
YKIIKQIGQGGFGKVYKCQH---KKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQ---ILLNHPHPFIVKMFYCFQDKQ

HLYIEMSLIEGTPLSEFISSMKE-----------KKT--FFSEKRIW-----TIFSQMIRALRYIHEDKGITHRDLKPANMILGEHD---KLTITDFGLA
..|| | ..||  |...|...|            .|.   |.|. .      ..| | . .| |.|. ..| |||.|| | .. .     .. |.|||..
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS

KDQKDF----------------SVMKSIVGTVVYW----CPEIVESKEYD----KKADIWAAGCVLYEMAALQPPFYATNLLS----------------L
| ....                  |....||  |      ||. ....||    .|.|||. |..||||   ..|||..|  .                |
KKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

AKKIAEGKFE--TAPL----DKYSAQVSDVIT----KCLTIDPTLRPNSVQI
 ..| .....   .|     .. | .. | |.    |.|  .|  |..  ||
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Kinase AqueK177.AA NEK2 431-633 29 2e-49 164.53 In-house 47-309 (319) Show / Hide 
Range on Protein: 431-633
Range on HMM: 47-309/319
Sequence Identity: 29% (79 aa)

SEVSMIHKKLRHPNIVQYFKCF--EESHHLYIEMSLIEGTPLSEFISSMKEKKTFFSEKRIWTIFSQMIRALRYIHE-----------------DKG---
||..   ..|.|||||.|      ...  ||| |   ||  ||  |.  .  .... |. || |. |. .||. .|                   .|   
SECNIL-RQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHT

ITHRDLKPANMILGEHDK---------------------------------------LTITDFGLAKDQK-DFSVMKSIVGTVVYWCPEIVESKEYDKKA
| |||.||||  | . .                                            |||||.  . | |  .. |||  |  || ..   |. | 
ILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKS

DIWAAGCVLYEMAALQPPFYATNLLSLAKKIAEGKFETAPLDKYSAQVSDVITKCLTIDPTLRPN
|||. ||..|||.|| ||| ||| . |. ||..|.|.. |   ||   ...|.  . .|.  ||.
DIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPY-QYSRHLNEIIHFMINVDHYHRPS
Kinase AqueK177.AA Ciliate-E2 429-637 23 5.4e-47 159.36 In-house 63-359 (365) Show / Hide 
Range on Protein: 429-637
Range on HMM: 63-359/365
Sequence Identity: 23% (74 aa)

IMSEVSMIH---------------KKLRHPNIVQYFKCFE--ESHHLYIEMSLIEGTPLSEFISSMKEKKTFF-------SEKRIWTIFSQMIR------
|..| ...                ..| ||||.... ||.    ...|. | ...|  | ..| ..| |...        .|| | .|. | ..      
IKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKA

---------ALRYIHEDKGITHRDLKPANMILGEHDKLTITDFGLAKDQKDF--------------------------------SVMKSIVGTVVYWCPE
         ||.|.|. . | |||.|| | ..     . |.||||.|...|.                                 . ..|.||  | .||
EFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPE

IVESKE---------YDKKADIWAAGCVLYEMAALQPPFYATNLLSLAKKIAEGKFETA----------------PLDKYSAQVSDVITK----CLTIDP
|...|.         ||.|.|||..|..||||   .|||         ..| ..|..                    .| | .. | | |    .|  ||
ILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP

TLRPN-SVQI
  |..   ||
EKRITGWEQI
Kinase AqueK177.AA ULK 436-629 27 1.2e-42 148.04 In-house 63-310 (324) Show / Hide 
Range on Protein: 436-629
Range on HMM: 63-310/324
Sequence Identity: 27% (70 aa)

IHKKLR---HPN--IVQYFKCFEESHH--LYIEMSLIEGTPLSEFISSMKE-----KKTFFSEKRIWTIFSQMIRALRYIHEDKGITHRDLKPANMILGE
| |||    |||  ||.....||.|.|  .|| | . .|  |...|   |.     .| ..||. .  .| | . .....|. ..| |||.||.|  . .
IMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK-HNIIHRDIKPQNILIHN

HDKLT------------ITDFGLAKD-Q---KDFSVMKSIV------GTVVYWCPEIVE----SKEYD-KKADIWAAGCVLYEMAALQPPFYATNLLSLA
..  |            |.|||.||  .   ..  .....|      ||  | .|.|..     |.|. .|.|||  ||..|||   ..||..    .. 
GQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQY

----KKIAEGKFE------TAPLDKY--------SAQVSDVITKCLTIDPT
    | |  || |      . |....        | .. | | ..|..|..
LYIQKLINNGK-EQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEK
Kinase AqueK177.AA TyrKc 373-641 20 1.6e-14 12.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 373-641
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YEVLELLGTGAYGSVYKVRKGPPRGSNFYALKEIQMTHPSLAGCSSLEERNGSIGKIMSEVSMIHKKL--RHPNIVQYFKCFEES-------HHLYIEMS
 . .. || ||.| ||| .          | | ..  .               .  .|.| ..  .||  .|||||. . .  ..       . |.| | 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA---------------REDFMREARIM-CKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVME

LIEGTPLSEFISSMKEKKTFFSEKRIWTIFSQMIRALRYIHEDKGITHRDLKPANMILGEHDKLTITDFGLAKDQKDF-------SVMKS---IVGT--V
. ..  | ... . ..|   .. |    .  |  .  .|.|. |.. ||||   |  .||     |.||||..| .|        .. ..     |   .
YMPHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHS-KNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML

-VYWC-PEIVESKEYDKKADIWAAGCVLYEMAAL-QPPFYA-----TNLLSLAKKIAEGKFETAPLD-------KYSAQVSDVITKCLTIDPTLRPNSVQ
 . |. ||    ...  | |.|. | ...|.  . |.| .       .   . ... .|.    | .         .. . .....|   ||  ||.  .
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE

IGGMI
|   .
IHECF
Kinase AqueK177.AA NEK 373-410 36 1.5e-11 37.32 In-house 1-41 (286) Show / Hide 
Range on Protein: 373-410
Range on HMM: 1-41/286
Sequence Identity: 36% (15 aa)

YEVLELLGTGAYGSVYKVRK---GPPRGSNFYALKEIQMTH
||... .| |..|.|||||.   |   . ..|..|.|.|..
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGN
Kinase AqueK177.AA NEK2 373-391 52 2.5e-08 24.01 In-house 1-19 (319) Show / Hide 
Range on Protein: 373-391
Range on HMM: 1-19/319
Sequence Identity: 52% (10 aa)

YEVLELLGTGAYGSVYKVR
||||. .|.| .|...|||
YEVLYTIGNGSFGRCRKVR
Kinase AqueK177.AA Ciliate-E2 373-392 40 4e-06 17.19 In-house 1-20 (365) Show / Hide 
Range on Protein: 373-392
Range on HMM: 1-20/365
Sequence Identity: 40% (8 aa)

YEVLELLGTGAYGSVYKVRK
|......|.|..|||||...
YKFIKKIGQGNFGSVYKCKV
Kinase AqueK177.AA ULK 373-389 44 0.000774 9.57 In-house 1-18 (324) Show / Hide 
Range on Protein: 373-389
Range on HMM: 1-18/324
Sequence Identity: 44% (8 aa)

YEVLELLGTGAYG-SVYK
|.. . || |..|  |||
YCLNHCLGKGSFGVKVYK