Gene AqueK180 (A.queenslandica)

AqueK180

Species: A.queenslandica
Alias: AqueK180
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK6

Sequence

Name Sequence Type Origin Length Description Download
AqueK180.AA Protein None 324 None Fasta, JSON
AqueK180.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of AqueK180.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK180.AA NEK6 38-289 79 5.3e-193 640.9 In-house 1-252 (252) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-252/252
Sequence Identity: 79% (201 aa)

FDIEKKIGQGQFSVVFKACSKTDSERVALKKIQIFEMVDAKARQDCLKEIELLQSLDHPNIIKYLASFVENNELYIVLELAEAGDLSRMIKHFKKRKQLI
| ||||||.|||| |..|    |   |||||.|||||.||||||||.|||.||..|.|||.|||.|||.||||| ||||||.|||.||||||||| | ||
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKHFKKQKRLI

PEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTSTAVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYNFKSDIWSLGCLLYELAALQ
||.|||.||||.||||.||| .|||||||||||||.|.. .||||||||||||||||||||||||||||||||||||.|||||||||||||||||.||||
PERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ

SPFYGDKMNLYSLCKKIEKCDYPPLPSDIYSQKLRDLVDSCINPNPEIRPDI
||||||||||||||||||.|||||||.|.||..||.||  ||.|.|| ||||
SPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase AqueK180.AA NEK 38-298 40 8.49999999999e-141 474.05 In-house 1-286 (286) Show / Hide 
Range on Protein: 38-298
Range on HMM: 1-286/286
Sequence Identity: 40% (116 aa)

FDIEKKIGQGQFSVVFKACSKTDSER-----VALKKIQIFEMVDAKARQDCL-KEIELLQSLDHPNIIKYLASFVENN--ELYIVLELAE-AGDLSRM--
..| ||||||.|..|.|. .| |.       ...|||. ... . | .|... .|. .|..|.||||.||  ||.|..   |.|| | .|  |||...  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-IKHFKKRKQLIPEKTIWRYFVQVCSALDHMHTR-----RVMHRDIKPANVFVTST----AVVKLGDLGLGRFFSSKTTAAHS-LVGTPYYMSPERIHET
 ||. |.......|..||..|.| |.||..|| |     ...||||||.|.| |.      .||.||.|. . ....|..|.. .|||||||||| ... 
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

GYNFKSDIWSLGCLLYELAALQS--PFYG-DKMNLYSLCKKIEKC-DYPPLPSDI-YSQKLRDLVDSCINPNPEIRPDIQRVYSVSQQ
.||.|||||||||.|||...|..  ||.. | ||..||..|| |. .|||.|| . |||.|..|. ......|| ||... . . .. 
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase AqueK180.AA S_TKc 38-302 29 3.8e-91 310.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 38-302
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

FDIEKKIGQGQFSVVFKACSKTDSERVALKKIQIFEMVDAKARQDCLKEIELLQSLDHPNIIKYLASFVENNELYIVLELAEA--GDLSRMIKHFKKRK-
..| .|||.| |..|.|.  | . ..||.|.|           .. ..||..|.. .||||.|.. .|.. ..||.|.|...   ||| ..||. .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-QLIPEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTSTAVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYNF-KSDIWSLGCLLYE
 . .|| ....|. |.|.||...| ....|||.||.|.....  ..|..| || |..       ....|||.||.|| .   ||.. |.|.||.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LAALQSPFYGDKMNLYSLCKKIEKCDYPPLPSDIYSQKLRDLVDSCINPNPEIRPDIQRVYS---VSQQMRSI
... . ||.    ... . |||             |. ..|... | . .|| || .  .     .  ..  .
MLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK180.AA NEK8 58-288 39 7.6e-83 236.33 In-house 21-268 (278) Show / Hide 
Range on Protein: 58-288
Range on HMM: 21-268/278
Sequence Identity: 39% (101 aa)

KTDS--ERVALKKIQIFEMVDAKARQDCLKEIELLQSLDHPNIIKYLASFVENNELYIVLELAEAGDLSRMIKHFKKRKQLIPEK---------------
| |.    | .| |   .| . | ||. . ||..|  |.||||| |. .| |.| | |..| |. | | .|| |  . | . .|.               
KEDQSHHLVIWKQINMHRM-SEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQH-QQNKLFEEERQLKQVNHCFNIYFNE

-TIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTST-AVVKLGDLGLGRFFSSKTTAAHS--LVGTPYYMSPERIHETGYNFKSDIWSLGCLLYELAAL
 .|  ||.|.|||. |||.  . |||.|..|.| |    |||.|| |.    ..|. .. .  .||||||||||      ||.|||.|.||| |||.. |
QMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCL

QSPFYGDKMNLYSLCKKIEKC-DYPPLPSDIYSQKLRDLVDSCINPNPEIRPD
   | ..  ||  |. ||  |  | |. || ||  .| || .|    || ||.
KRAFEAS--NLPALVWKIMQCRAYEPI-SDHYSNEMRMLVHNCLQQDPEQRPS
Kinase AqueK180.AA NEK1 38-292 37 1.1e-81 277.65 In-house 1-270 (276) Show / Hide 
Range on Protein: 38-292
Range on HMM: 1-270/276
Sequence Identity: 37% (103 aa)

FDIEKKIGQGQFSVVFKACSKTDSERVALKKIQIFEMVDAKARQDCLKEIELLQSLDHPNIIKYLASFVENNE--LYIVLELAEAGDLSRMIKHFKKRKQ
... |.||.| |  .... .| |.   ..| |.. .|   | |.. ..|  .|. ..||||.||  ||.||    |||| | ...||| . |.  | . .
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKM-QEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGK

LIPEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVT--STA---------------VVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYN
|..| .|  .|.| | || |.| |...|||||. |.| |  .                 .||||| |  |  .. .  |   .||||| ||| .   .||
LFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYN

FKSDIWSLGCLLYELAALQSPFYGDKMNLYSLCKKIEKCDYPPLPSDIYSQKLRDLVDSCINPNPEIRPDIQRV
 ||||||||| |||| .|  || . ..    |  || .  |||.|.  ||..|. || .  . ||. || .. .
NKSDIWSLGCVLYELCTLKHPFEANNWK--NLVLKICQGTYPPIPP-HYSYELQSLVSQMFKRNPRHRPSVNQI
Kinase AqueK180.AA Pkinase 38-290 25 1.2e-78 272.43 Pfam 1-285 (293) Show / Hide 
Range on Protein: 38-290
Range on HMM: 1-285/293
Sequence Identity: 25% (75 aa)

FDIEKKIGQGQFSVVFKACSKTDSERVALKKIQIFEMVDAKARQDCL-KEIELLQSLDHPNIIKYLASFVENNELYIVLELAEAG----DLSRMIKHFKK
. |..|||.| |..|.|.. | ....||.|.|   .  . | ... .  ||.....|.||||.... .| .....|.|.|..| |    ||...|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

RKQLI--PEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTSTAVV----KLGDLGLGRFF-SSKTTAAHSLVGTPYYMSPERIH-ETGYNFKSDIW
|.  .  .|... .|. |....|...| ....|||.||.|... .. ..    |..| || ..|   . . .....|||.||.|| |   ..|  |.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGCLLYELAALQSPFYGD----KMNLYSLCKKIEKCDYPPLPSDIYS-------------------QKLRDLVDSCINPNPEIRPDIQ
|.||.|||..  . ||.|.    ... . . ..| .....   .  .|                   . ..|....|....|. || ..
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE
Kinase AqueK180.AA CAMK 43-290 20 1.1e-72 233.37 In-house 1-417 (425) Show / Hide 
Range on Protein: 43-290
Range on HMM: 1-417/425
Sequence Identity: 20% (86 aa)

KIGQGQFSVVFKACSKTDS------------ERVALKKIQIFEMVD-------------------------AKARQDCLKEIELLQS-------LDHPNI
..|.|.|..|.... | .             ..|| | |    . |                         .| |.  ..|||....       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKYLASFVE-------------------NNELYIVL---ELAEAG----D-LSRMIKH-----------FKKRKQLIPEKTIWRYFVQVCSALDHMHTRR
|| .  .                     ....|.|.   |... |    | ... ..|           .  ..  ..|.   ||| |.|||....| . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

VMHRDIKPANVFVTST-----------------AVVKLGDLGLGRFFSSK-----------------------TTAAHSLVGTPYYMS-PERIH------
..|||.|| |. ...                  . .|. | |. ..| ..                       .   .  .|||.||. || .       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ETGYNFKSDIWSLGCLLYELAALQSPFYGD-----------KMNLYSLCKKIEKCDY--PPLP------------SDIYSQK--------LR
        ...|..|.|.||.|..|| .    .|||||           .||.| |..|| |..|  || .             |  |.          .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLVDSCINPNPEIRPDIQ
||. .. ...|| |. |.
DLIRKMLQVDPEKRMTIE
Kinase AqueK180.AA STE 38-288 23 5.4e-72 245.49 In-house 1-347 (359) Show / Hide 
Range on Protein: 38-288
Range on HMM: 1-347/359
Sequence Identity: 23% (84 aa)

FDIEKKIGQGQFSVVFKACSKT---------------DSERVALKKIQIFEM--------------VDAKARQDCLKEIELLQSLD--HPNIIKYLASFV
... .|||.| | .|.||. .                  |..| |.. . .               .. . .|. ||||.... ..  ||||.||. ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EN-------NELYIVLELAEAGDLSRMIK-HFKKRKQL---------IPEKTIWRYFVQVCSA-LDHMHTRRVMHRDIKPANVFVTSTAVVKLGDLGLGR
 .       .||.|..|. ..| |. .||  ... |.|         .||. | .. .|.. . |.. |  ...||||||||...     ||| | |.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FFSSK--------------TTA--AHSLVGTPYYMSPERIHE------TGYNFKSDIWSLGCLLYELAALQSPFYG-DKM-NLYSLCKKIEKC-------
 ....              |..    ..|||| .|.||.|         ||..|.|||||||.. |.|  . |.     | ...   ... ..       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----DYPPLPSD------------------IYSQKLRDLVDSCINPNPEIRPD
    . ||||..                   .|....| .. | . .|. ||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase AqueK180.AA Ciliate-E2 38-290 23 2e-66 227.01 In-house 1-357 (365) Show / Hide 
Range on Protein: 38-290
Range on HMM: 1-357/365
Sequence Identity: 23% (86 aa)

FDIEKKIGQGQFSVVFKACSKTDSERVALK----------------------KIQIFEMVDAKAR-QDCLKEIE----------LLQSLDHPNIIKYLAS
... ||||||.|..|.|.. . . ...|.|                      ||..  .. .. . .. ..||.          .|..|.||||||.  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FV--ENNELYIVLELAEAGDLSRMIKHF-KKRKQLIP------EKTIWRYFVQVCS---------------ALDHMHTRR-VMHRDIKPANVFVTSTAVV
|    .| .|.|.|... |||   ||.. |||.. |.      || | ... |...               || ..| .  ..|||||| |...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLGDLGLGRFFSSKTT-------------------------------AAHSLVGTPYYMSPERIH---------ETGYNFKSDIWSLGCLLYELAALQSP
|. |.|| .... .                                  .....|||.||.|| .          ..||..|.||||||..|||.   . |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYGDKMNLYSLCKKIE-KCDYPPL--------------PSDIYSQKLRDLVDS----CINPNPEIRPD-IQ
|         . .... |.|.|.                 .  ||.  ||       ... .|| |.. ..
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWE
Kinase AqueK180.AA ULK 38-284 26 1.4e-65 224.19 In-house 1-310 (324) Show / Hide 
Range on Protein: 38-284
Range on HMM: 1-310/324
Sequence Identity: 26% (81 aa)

FDIEKKIGQGQFS-VVFKA-CSKTD--SERVALKKIQIFEMVDAKARQD------CLK-EIELLQSLD---HPN--IIKYLASFVEN--NELYIVLELAE
. . ...|.|.|  .|.|. . ||.   . || |.|....| . | .|.       || ||.... |.   |||  |.|..  | .   | .||..|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGDLSRMIKHFKK-----RKQLIPEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTST------------AVVKLGDLGLGRFFS---SKTTAAHS
 |||.  ||  ||     .|. ..|. .  .| | |... ..| . ..||||||.|  ..               |.|..| |.....       .  ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LV------GTPYYMSPERIHETG----YN-FKSDIWSLGCLLYELAALQSPFYGDKMNLY----SLCKK-------IEK--CDYPPL-PSDIYSQKLRDL
.|      |||.||.|. ... |    |. .|.|||||||..||.   . ||.......|    .| ..       |..   ..|.  .... |....||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VDSCINPNPE
   ..  ...
IRRMLQYDEK
Kinase AqueK180.AA ULK 38-284 25 2.2e-65 223.51 In-house 1-315 (329) Show / Hide 
Range on Protein: 38-284
Range on HMM: 1-315/329
Sequence Identity: 25% (81 aa)

FDIEKKIGQGQFSVVFKA-CSKTD---SERVALKKIQIFEMVDAKARQD------CLK-EIELLQSLD--------HPNIIKYLASFVEN--NELYIVLE
. . ...|.|.| .|.|. . ||.    | || |.|....|   .  |.      .|| ||.... |.        ||||.|..  | .   | .||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LAEAGDLSRMIKHFKK------RKQLIPEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTST------------AVVKLGDLGLGRFFSSK---TT
. . |||.  ||  ||      .|. ..|. .  .| | .... ..| ....||||||.|. ..               |.|..| |.......      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AAHSLV------GTPYYMSPERIHETG----YN-FKSDIWSLGCLLYELAALQSPFYGD--KMNLYSLCKKIEK------------CDYPPL-PSDIYSQ
 ... |      |||.||.|. ... |    |. .|.|||||||..||.   . |||.   . .|. . | |..             ..|.  .... |.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

KLRDLVDSCINPNPE
...||   ..  ...
ECKDLIRRMLQYDEK
Kinase AqueK180.AA NEK4 38-302 35 9.7e-64 218.07 In-house 1-257 (257) Show / Hide 
Range on Protein: 38-302
Range on HMM: 1-257/257
Sequence Identity: 35% (95 aa)

FDIEKKIGQGQFSVVFKACSKTDSERVALKKIQIFEMVDAKARQDCLKEIELLQSLDHPNIIKYLASFVENNE--LYIVLELAEAGDLSRMIKHFKKRKQ
... | .|.| .  |.   .. |  .  .||..     . . |.. ..|..||  | ||||..|  |.   |   ||||.   | ||| |  |  ... |
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFL-KNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLK--QQKNQ

LIPEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTSTAVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYNFKSDIWSLGCLLYELAA
...|. .   |||.  ||  || ....||| |  |.| | . ..|.||.|. |    .   |  ..|||||||||      |..||||||||| .||.. 
FLEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMIT

LQSPFYGDKMNLYSLCKKIEKCDYPPLPSDIYSQKLRDLVDSCINPNPEIRPDIQRVYSVSQQMRSI
|   |    ||  ||  .| .   ||.| . ||| | .||   ..  |. || |  ..    ||  |
LKHAFDAKDMN--SLIYQIIQGQPPPMPPN-YSQDLQNLVYQMLEKQPTKRPSIFDIF----QMPYI
Kinase AqueK180.AA TyrKc 38-299 20 1e-29 106.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 38-299
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FDIEKKIGQGQFSVVFKACSKTDSERVALKKIQIFEMVDAKARQDCLKEIELLQSL--DHPNIIKYLASFVEN-------NELYIVLELAEAGDLSRMIK
   .||.| |.| .|.|.  |   . || |...         |.| ..|.... .|  .||||.. ..  ..          |.||.|... |||   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

HFKKRKQLIPEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTSTAVVKLGDLGLGRFFSSK--------TTAAHSLVGTP-----YYMSPERIHET
  ...   .. |.   . .|...  .. | ... |||.   |. |..  .|| .| || |.  ..        .  . .  |.        |.|| | . 
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYNFKSDIWSLGCLLYELAALQSPFYGD----KMNLYSLCKKIEKCDYPPLPSD-------IYSQKLRDLVDSCINPNPEIRPDIQRVYSVSQQM
 ...|||.|| | ...|.  .  . | .    .|. . . ..... ...| | .       . .... ..  .| . .|| ||  . .    ...
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase AqueK180.AA Pkinase_Tyr 38-233 26 7.1e-27 91.65 Pfam 1-207 (270) Show / Hide 
Range on Protein: 38-233
Range on HMM: 1-207/270
Sequence Identity: 26% (57 aa)

FDIEKKIGQGQFSVVFKACSK----TDSERVALKKIQIFEMVDAKA--RQDCLKEIELLQSL-DHPNIIKYLASFV-ENNE--LYIVLELAEAGDLSRMI
  . ||.|.|.| .|.|.  |     .   || |..   |  . ..  |.| ..|.... .| .||||.....  . .     .|||.|... |||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KHFKKR---KQLIPEKTIWRYFVQVCSALDHMHTRRVMHRDIKPANVFVTSTAVVKLGDLGLGRFF--SSKT-TAAHSLVGTPYYMSPERIHETGYNFKS
   .|.   || .. |..  . .|....... . ..  |||.   |. ||.. ||| .| || |     .   .....       |.|| |..  .. ||
---RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS

DIWSLGCLLYEL
|.|| | |..|.
DVWSFGVLMWEI