Gene AqueK190 (A.queenslandica)
AqueK190
Species: A.queenslandica
Alias: AqueK190
External Links:
Annotation:
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK190.AA | Protein | None | 857 | None | Fasta, JSON |
| AqueK190.kin_dom | Protein Kinase Domain | None | 65 | None | Fasta, JSON |
Protein domains of AqueK190.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK190.AA | TKL-Unique | 97-171 | 23 | 1.1e-08 | 27.01 | In-house | 51-139 (290) | Show / Hide |
Range on Protein: 97-171 Range on HMM: 51-139/290 Sequence Identity: 23% (21 aa) KLR-HPNILQFLGVVFPKTNLLP--IILTEQLDT-TLNQVLH----------RVPNLPESLKISLIHDVSLGLEAMHGSSPALTHGNLT ||. ||||... |. . .. | .| .| .. .|. ||| . .|. ........|...|.. | ..| .|..|. KLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLK |
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| Kinase | AqueK190.AA | TKL | 77-186 | 17 | 2.9e-08 | 25.88 | In-house | 61-196 (364) | Show / Hide |
Range on Protein: 77-186
Range on HMM: 61-196/364
Sequence Identity: 17% (25 aa)
EDKDSMSLTERLAEETHRFAKLRHPNILQFLGVVFPKTNL-----------LPIILTEQL-DTTLNQVLHRVPNLPESLKISLIHDVSLGLEAMHGSS--
.|.... . ... ||. .||||||.||.|... .. . | .| .| .|| ........|...|.. .| .
NDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPK
----PALTHGNLTASTVFLTPSLT--------------AKLS
|.. | .|. . ... .| .|..
WCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKIC
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| S_TKc | AqueK190.AA | S_TKc | 41-313 | 15 | 7.6e-08 | -61.88 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 41-313
Range on HMM: 1-231/231
Sequence Identity: 15% (48 aa)
TLSEVTIGGG-----LQAVAVLPTNEEEASRLLQPGTEDNEEDKDSMSLTERLAEETHRFAKLRHPNILQFLGVVFPKTNLLPIILTEQLDT---TLNQV
.|| | ... . |... | . |.. | | .|||| ....| . .| .|. .| ..
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDY
LHRVPN------LPESLKISLIHDVSLGLEAMHGSSPALTHGNLTASTVFLTPSLTAKLS-------YPPIYSVFDDTAGGNVESGDISFTSHLQAQLNS
... . .|| .... . ..|| .| | | . ..|. . |.. .
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL--------------------------------
SSNGYHISSAFTG---------ISNRGF-KDDIFSLGELMVHVITQQRPKRIGPGQSPSLLQQTERIDGNHLLRGLIMQCLQKDPVLRPTASEIVQ---E
. | | . |. | |. |.| .. .. . | . | .... . .. .|..|||||| |||| |. | .
--------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD
VKMSITT
.|.
IKCHPWF
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| Kinase | AqueK190.AA | FRAY | 264-302 | 42 | 2.9e-07 | 18.26 | In-house | 228-270 (277) | Show / Hide |
Range on Protein: 264-302 Range on HMM: 228-270/277 Sequence Identity: 42% (19 aa) GQSPSLLQQTERIDG------NHLLRGLIMQCLQKDPVLRPTASE . .||| .|. |. |. . .| .|||||| |||||| NDPPSL--ETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASE |
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| Kinase | AqueK190.AA | TK | 79-186 | 10 | 8.8e-07 | 17.94 | In-house | 63-293 (486) | Show / Hide |
Range on Protein: 79-186
Range on HMM: 63-293/486
Sequence Identity: 10% (24 aa)
KDSMSLTERLA-------------EETHRFAKLR-----HPNILQFLGVVFPKTN----------LLPIILTEQLD-TT----LNQVLHRVPN-------
.|.|| .|... || . .... ||||....||.. . . ..|..| . | . |.. ..
GDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQD
---------------------------------------------------------------------LPESLKISLIHDVSLGLEAMHGSSP----AL
|. .. .... |.| .| .
CPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNF
THGNLTASTVFLTPSLT-----------AKLS
|..| | . .. ... .|..
VHRDLAARNCLVGENNVCKWHFDGCGPVCKIA
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| Kinase | AqueK190.AA | NRBP | 155-310 | 22 | 1e-06 | 19.04 | In-house | 116-261 (261) | Show / Hide |
Range on Protein: 155-310 Range on HMM: 116-261/261 Sequence Identity: 22% (36 aa) LEAMHGSSPALTHGNLTASTVFLTPSLTAKLSYPPIYSVFDDTAGGNVESGDISFTSHLQAQLNSSSNGYHISSAFT--GISNRGFKDDIFSLG--ELMV |. .| ..| . |||||. |.|. | | .| .|.... . | .... . . ||.| | | . LSYLHSCDPPIIHGNLTCDTIFIQHNGLIK-----IGCVW-----------PDAIHHHVRTCREEMRNMHFFAPEYGILEVTDLTTAVDIYSFGMCALEM HVITQQRPKRIGPGQ--SPSLLQQTERIDGNHLLRGLIMQCLQKDPVLRPTASEIVQEVKMS |. | | . . .|.. . . . | .| .|||||| ||.| |.. . AVLEIQSGCQNGESEYVTEEAIQRAIHSLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF |
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| Kinase | AqueK190.AA | NEK | 282-309 | 42 | 1e-06 | 20.0 | In-house | 259-286 (286) | Show / Hide |
Range on Protein: 282-309 Range on HMM: 259-286/286 Sequence Identity: 42% (12 aa) LRGLIMQCLQKDPVLRPTASEIVQEVKM |. || |.||||| .||....| . . LQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | AqueK190.AA | TKL | 282-307 | 30 | 2e-06 | 19.03 | In-house | 339-364 (364) | Show / Hide |
Range on Protein: 282-307 Range on HMM: 339-364/364 Sequence Identity: 30% (8 aa) LRGLIMQCLQKDPVLRPTASEIVQEV .. |...| . || ||...||... MKKLMQDCWDHDPEKRPSFQEILKRL |
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| Kinase | AqueK190.AA | LRRK | 282-309 | 39 | 2e-06 | 19.01 | In-house | 324-351 (351) | Show / Hide |
Range on Protein: 282-309 Range on HMM: 324-351/351 Sequence Identity: 39% (11 aa) LRGLIMQCLQKDPVLRPTASEIVQEVKM . ||..| | || ||..|.||. . YQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | AqueK190.AA | WEE | 282-309 | 32 | 2e-06 | 17.97 | In-house | 270-297 (297) | Show / Hide |
Range on Protein: 282-309 Range on HMM: 270-297/297 Sequence Identity: 32% (9 aa) LRGLIMQCLQKDPVLRPTASEIVQEVKM |..||.. ...|| .|||.....| .. LKQLIKWMMHPDPEQRPTCQQLLQHPVL |
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| Kinase | AqueK190.AA | TKL-Unique | 277-307 | 35 | 3e-05 | 14.69 | In-house | 260-290 (290) | Show / Hide |
Range on Protein: 277-307 Range on HMM: 260-290/290 Sequence Identity: 35% (11 aa) DGNHLLRGLIMQCLQKDPVLRPTASEIVQEV . . .| || || ||. ||. .||. . HCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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| Kinase | AqueK190.AA | TK | 285-307 | 39 | 3.5e-05 | 12.5 | In-house | 464-486 (486) | Show / Hide |
Range on Protein: 285-307 Range on HMM: 464-486/486 Sequence Identity: 39% (9 aa) LIMQCLQKDPVLRPTASEIVQEV |..|| ..|| ||| |..... LMQQCWHYDPEDRPTFSQLHEQL |
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| Kinase | AqueK190.AA | DRK | 97-108 | 75 | 0.000223 | 10.78 | In-house | 53-64 (258) | Show / Hide |
Range on Protein: 97-108 Range on HMM: 53-64/258 Sequence Identity: 75% (9 aa) KLRHPNILQFLG .|||||| ||.| QLRHPNICQFMG |
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| TyrKc | AqueK190.AA | TyrKc | 40-307 | 16 | 0.00024 | -152.37 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 40-307 Range on HMM: 1-280/280 Sequence Identity: 16% (52 aa) FTLSEVTIGGG-----LQAVAVLPTNEEEASRL-----LQPGTEDNEEDKDSMSLTERLAEETHRFAKL--RHPNILQFLGVVFP--------KTNLLPI || .. .| | .... . |.... | . .| || .||||....||. . .. ITLGKK-LGEGAFGEVYKGTWK---------IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM ILTEQLDTTLNQVLHRVPN-LPESLKISLIHDVSLGLEAMHGSSPALTHGNLTASTVFLTPSLTAKLSYP----PIYSVFDDTAGGNVESGDISFTSHLQ . . | |.. |.. . |. . ..| .... | | | . | | | . .. .|.| | ||. |..| ... .. ..| . EYMPHGD--LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDD--DQQG--ESKDYYRKKEHKG AQ--LN-------SSSNG-YHISS-------------AFTGISNRG-FKDDIFSLGELMVHVITQQRPKRIGPGQSPSLLQQTERI----DGNHLLRGLI . | . | . . | . . | . | |.. .| . |... . . . . . .. GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY--------P-MSFVCCPDEMYQ-IM MQCLQKDPVLRPTASEIVQEV || . || ||| |||... KQCWHEDPEDRPTFSEIHECF |
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| Kinase | AqueK190.AA | Dicty4 | 96-108 | 61 | 0.000346 | 10.06 | In-house | 53-65 (277) | Show / Hide |
Range on Protein: 96-108 Range on HMM: 53-65/277 Sequence Identity: 61% (8 aa) AKLRHPNILQFLG .|.|||||..|.| CKIRHPNICLFMG |
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| Kinase | AqueK190.AA | Pkinase_Tyr | 285-307 | 47 | 0.001775 | 12.4 | Pfam | 248-270 (270) | Show / Hide |
Range on Protein: 285-307 Range on HMM: 248-270/270 Sequence Identity: 47% (11 aa) LIMQCLQKDPVLRPTASEIVQEV |..|| ..|| ||| |||... LMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | AqueK190.AA | Pkinase | 282-307 | 42 | 0.002469 | 12.87 | Pfam | 266-293 (293) | Show / Hide |
Range on Protein: 282-307 Range on HMM: 266-293/293 Sequence Identity: 42% (12 aa) LRGLIMQCLQKDPVLRPTASEIVQE--V .. .| ||.||| |||| .|.| . CKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | AqueK190.AA | DRK | 285-309 | 28 | 0.003384 | 6.72 | In-house | 234-258 (258) | Show / Hide |
Range on Protein: 285-309 Range on HMM: 234-258/258 Sequence Identity: 28% (7 aa) LIMQCLQKDPVLRPTASEIVQEVKM |. |. || ||. |... LMNDCWNEDPQHRPSMQECLERLEA |
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| Kinase | AqueK190.AA | Dicty4 | 282-309 | 33 | 0.003473 | 6.67 | In-house | 248-277 (277) | Show / Hide |
Range on Protein: 282-309 Range on HMM: 248-277/277 Sequence Identity: 33% (10 aa) LRGLIMQCLQKDPVLRPTASEIVQE--VKM .. || |. .|| ||. .||.|. WKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | AqueK190.AA | Pkinase | 96-159 | 19 | 0.046256 | 8.37 | Pfam | 55-125 (293) | Show / Hide |
Range on Protein: 96-159 Range on HMM: 55-125/293 Sequence Identity: 19% (14 aa) AKLRHPNILQFLGVVFPKTNLLPIILTEQLDT-----TLNQVLH--RVPNL--PESLKISLIHDVSLGLEAMH ..|.||||....... |... . .| .. | ... | .. .| .. . . ||| .| KRLNHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCH |
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| Kinase | AqueK190.AA | Pkinase_Tyr | 97-123 | 31 | 0.049328 | 7.51 | Pfam | 59-87 (270) | Show / Hide |
Range on Protein: 97-123 Range on HMM: 59-87/270 Sequence Identity: 31% (9 aa) KL-RHPNILQFLGVVFPKTNL-LPIILTE .| .||||....||. .. ..| .| QLGHHPNIVRLYGVCTDQGEPNQIYIVME |
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| PDZ | AqueK190.AA | PDZ | 428-509 | 32 | 6.1e-22 | 80.14 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 428-509 Range on HMM: 1-80/80 Sequence Identity: 32% (30 aa) QSFGFSITGGKGAASTLLEGDESIFITRLAPGGLAEKDGR-----LKPGDKLIMVNG-VDMTSATRPDALSALMSSGD-----VCTMVVTREE ...||||.| |||... ||| |||.|| |.|||... ||| ......| .|. .| ..|. . |..| |.. GGLGFSIVG-------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | AqueK190.AA | PDZ | 420-506 | 29 | 2.6e-19 | 68.74 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 420-506 Range on HMM: 1-86/86 Sequence Identity: 29% (27 aa) ELHKES--SDQSFGFSITGGKGAASTLLEGDESIFITRLAPG-GLAEKDGRLKPGDKLIMVNGVDMTSATRPDALSALMSSGD-VCTMVVT ....| . ...|||| ||... . |..|.|... || | ||..||...||..| .||.|... | .| |...|.. . .... QVTLEKQDKRGGLGFSIKGGNDQRH-----DQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| Kelch_1 | AqueK190.AA | Kelch_1 | 658-703 | 26 | 7.5e-10 | 39.08 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 658-703 Range on HMM: 1-45/45 Sequence Identity: 26% (12 aa) ARMHAAVVSLGTSLVVAGGRNNKNTLNCVEVFNFASQQWYTAHPLT .| ...|.... . |.||... . ||.||... ..|| |.. PRCGHGVCVHNGKIYVIGGCDG-QYLNSVECYDPETNQWTRCPPMP |
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| Kelch | AqueK190.AA | Kelch | 620-669 | 17 | 0.000313 | 19.3 | SMART | 1-55 (55) | Show / Hide |
Range on Protein: 620-669 Range on HMM: 1-55/55 Sequence Identity: 17% (10 aa) KVTVVGGFDSAT------QSCSAQLFAWNEMEGSWLGSLTPMPTARMHAAVVSLGT .. |.||.. .. ..|.. . .. .. | ...|||..|....|.... CIYVIGGWNGNHCCEPGEMQCLNSVECYDPETNKWR-MCPPMPYPRCYHGVCVHNG |
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| Kelch | AqueK190.AA | Kelch | 670-716 | 23 | 0.000508 | 17.46 | SMART | 1-55 (55) | Show / Hide |
Range on Protein: 670-716 Range on HMM: 1-55/55 Sequence Identity: 23% (13 aa) SLVVAGGRNN--------KNTLNCVEVFNFASQQWYTAHPLTLEQSSMKGLCHNG . |.||.|. ...|| ||... ...|. |.. . . ||| CIYVIGGWNGNHCCEPGEMQCLNSVECYDPETNKWRMCPPMPYPRCYHGVCVHNG |
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| Kelch_1 | AqueK190.AA | Kelch_1 | 579-608 | 30 | 0.005071 | 14.6 | Pfam | 16-45 (45) | Show / Hide |
Range on Protein: 579-608 Range on HMM: 16-45/45 Sequence Identity: 30% (9 aa) IVGGHYSNNSGSIFEYDPEKDSWNTLTTSP ..||. .. . |.. ||||...| ... | VIGGCDGQYLNSVECYDPETNQWTRCPPMP |
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| Kelch | AqueK190.AA | Kelch | 578-619 | 20 | 0.009904 | 6.14 | SMART | 3-55 (55) | Show / Hide |
Range on Protein: 578-619 Range on HMM: 3-55/55 Sequence Identity: 20% (11 aa) VIVGGHYS---------NNSGSIFEYDPEKDSWNTLTTSPV--WFFGLTVFQD ..||. . . |.. |||| . | .. |. .|..|... YVIGGWNGNHCCEPGEMQCLNSVECYDPETNKWRMCPPMPYPRCYHGVCVHNG |
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| Kelch_1 | AqueK190.AA | Kelch_1 | 611-648 | 21 | 1.407342 | 5.84 | Pfam | 4-38 (45) | Show / Hide |
Range on Protein: 611-648 Range on HMM: 4-38/45 Sequence Identity: 21% (8 aa) FFGLTVFQDKVTVVGGFDSATQSCSAQLFAWNEMEGSW ..| .|...|. |.||.|. ... .... ....| GHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQW |
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| Kelch | AqueK190.AA | Kelch | 774-825 | 14 | 0.009572 | 6.27 | SMART | 1-55 (55) | Show / Hide |
Range on Protein: 774-825 Range on HMM: 1-55/55 Sequence Identity: 14% (8 aa) KIVTIGGAHRDSEDL---SDPTSTVYALCEDPYSWLEVGELPDPLSHSCAVTISD .| ||| .. . .. ...| . . | .. .| | ........ . CIYVIGGWNGNHCCEPGEMQCLNSVECYDPETNKWRMCPPMPYPRCYHGVCVHNG |
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| Kelch_1 | AqueK190.AA | Kelch_1 | 762-812 | 21 | 0.127432 | 9.58 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 762-812 Range on HMM: 1-45/45 Sequence Identity: 21% (11 aa) PNTYSAVALSGGKIVTIGGAHRDSEDLSDPTSTVYALCEDPYSWLEVGELP | .. .|. .||| ||| ....|... . .| .. ..| PRCGHGVCVHNGKIYVIGGCDG------QYLNSVECYDPETNQWTRCPPMP |
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| Kelch_1 | AqueK190.AA | Kelch_1 | 815-846 | 18 | 1.425534 | 5.82 | Pfam | 1-30 (45) | Show / Hide |
Range on Protein: 815-846 Range on HMM: 1-30/45 Sequence Identity: 18% (6 aa) LSHSCAVTISDEEVLVIGGRYEDGKDTDAVYR ....|. . .. ||||. .. |.. PRCGHGVCVHNGKIYVIGGCDG--QYLNSVEC |
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