Gene AqueK221 (A.queenslandica)

AqueK221

Species: A.queenslandica
Alias: AqueK221
External Links:
Annotation:

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
AqueK221.AA Protein None 1056 None Fasta, JSON
AqueK221.kin_dom Protein Kinase Domain None 119 None Fasta, JSON

Protein domain

Protein domains of AqueK221.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK221.AA RGC 581-701 32 4.1e-30 103.04 In-house 1-131 (300) Show / Hide 
Range on Protein: 581-701
Range on HMM: 1-131/300
Sequence Identity: 32% (42 aa)

NGKIVKVHKMKMN--ISTLDL--NLRKTMLQILNFDHENICPFIGCILQGPTI-----VGMMHEYCSHGSLYEVLRNPNIVFDKQFRVLFATDIIKGLTY
.|  | ..| ...  .  .|.  . .. . |  . .|.|...||| .. .| .     . ...|||| ||| ..|.| .|  |  |.  | .||.||. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHS-HKLTHGRLSSVTCVIGNLWKLKLTDYG
||.     ||.|.| .||.   | .|.||.|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFG
Kinase AqueK221.AA RGC 581-701 32 5.8e-30 103.04 In-house 1-131 (300) Show / Hide 
Range on Protein: 581-701
Range on HMM: 1-131/300
Sequence Identity: 32% (42 aa)

NGKIVKVHKMKMN--ISTLDL--NLRKTMLQILNFDHENICPFIGCILQGPTI-----VGMMHEYCSHGSLYEVLRNPNIVFDKQFRVLFATDIIKGLTY
.|  | ..| ...  .  .|.  . .. . |  . .|.|...||| .. .| .     . ...|||| ||| ..|.| .|  |  |.  | .||.||. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHS-HKLTHGRLSSVTCVIGNLWKLKLTDYG
||.     ||.|.| .||.   | .|.||.|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFG
Kinase AqueK221.AA TKL 601-701 21 4e-14 47.27 In-house 72-199 (364) Show / Hide 
Range on Protein: 601-701
Range on HMM: 72-199/364
Sequence Identity: 21% (29 aa)

LRKTMLQILNFDHENICPFIG-CILQGPTI-----------VGMMHEYCSHGSLYEVLRNPNIVFDKQFRVLFATDIIKGLTYLHSHK--------LTHG
... ........|.||..|.| |.  ...             ..  |||..|||...|         . |. .| || .|. ||||..        . | 
EEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHR

RLSSVTCVIGNLWK--------------LKLTDYG
 | |  . . . |.              .|..|.|
DLKSKNILVDENWTNVSNYMYNPNADWCCKICDFG
Kinase AqueK221.AA MLK 611-676 30 3.8e-13 42.09 In-house 62-144 (291) Show / Hide 
Range on Protein: 611-676
Range on HMM: 62-144/291
Sequence Identity: 30% (25 aa)

FDHEN----ICPFIGCILQGPTIVGMMHEYCSHGSLYEVLRNPN-------------IVFDKQFRVLFATDIIKGLTYLHSHK
..|.|    |..| |..|| |  ..   |||..||||.||.. .             .| | .. . .|... .|. ||||..
LSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMA
Kinase AqueK221.AA TKL-Unique 610-701 29 1.2e-12 41.07 In-house 51-162 (290) Show / Hide 
Range on Protein: 610-701
Range on HMM: 51-162/290
Sequence Identity: 29% (33 aa)

NFD-HENICPFIGCIL-QGPTIV--GMMHEYCSHGSLYEVLR---------NPNIVFDKQFRVLFATDIIKGLTYLHSHK--LTHGRLSSVTCVIGNL--
... |.||  ..|    . ...    .  |||..||||.||          |.|. .. | || .| || .|. |||. .   .|. | |    . |   
KLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSN

---WKLKLTDYG
   |. |. | |
IAEWNIKICDFG
Kinase AqueK221.AA LZK 612-701 37 4.5e-12 36.91 In-house 45-132 (241) Show / Hide 
Range on Protein: 612-701
Range on HMM: 45-132/241
Sequence Identity: 37% (34 aa)

DHENICPFIGCILQGPTIVGMMHEYCSHGSLYEVLRNPNIVFDKQFRVLFATDIIKGLTYLHSHKLTHGRLSSVTCVIGNLWKLKLTDYG
.|.||  | |   | |    .| |||.|| ||||||. . .  . . |   ..| .|. |||.||  |  | |    | .   .|  |.|
KHPNIIEFKGVCTQSPCYCIIM-EYCPHGQLYEVLRERRTITPQLM-VDWSKQIAQGMHYLHQHKIIHRDLKSPNILISHNDVVKICDFG
Kinase AqueK221.AA TESK 606-689 31 8.9e-10 26.58 In-house 44-127 (292) Show / Hide 
Range on Protein: 606-689
Range on HMM: 44-127/292
Sequence Identity: 31% (27 aa)

LQILN-FDHENICPFIG-CILQGPTIVGMMHEYCSHGSLYEVLRNPNIVFDKQFRVLFATDIIKGLTYLHSHKLTHGRLSSVTCVI
.| .|   | ||  | | |. ||   .  . || . |.| ..| . ...   . ..  |.|| .|..||||    |  | |  | .
VQLMNKLQHPNILRFMGVCVHQG--QLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLV
Kinase AqueK221.AA TK 589-701 11 1e-09 27.94 In-house 58-296 (486) Show / Hide 
Range on Protein: 589-701
Range on HMM: 58-296/486
Sequence Identity: 11% (28 aa)

KMKMNISTLDLNLRKT-----------------MLQILN---FDHENICPFIGCILQGPT-----------IVGMMHEYCSHGS----LYEVLRNPNIV-
||..  .. . . ..                  ......   ..|.||  ..|...|| .            . .. ||..||.    | . ||.     
KMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKF

--------------------------------------------------------------------------FDKQFRVLFATDIIKGLTYLHSH---
                                                                          .. . .. .. .| .|. ||||.   
QHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE

---KLTHGRLSSVTCVIGNLWK-----------LKLTDYG
   .. |. |    | .|.  .            |..|.|
FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFG
Kinase AqueK221.AA DRK 613-674 38 1.2e-09 28.88 In-house 56-116 (258) Show / Hide 
Range on Protein: 613-674
Range on HMM: 56-116/258
Sequence Identity: 38% (24 aa)

HENICPFIGCILQGPTIVGMMHEYCSHGSLYEVLRNPNIVFDKQFRVLFATDIIKGLTYLHS
| ||| |.|  .  | |   | || . |||| .| .. |  |   .   . |. ||..|||.
HPNICQFMGTCNNPPDICICM-EYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHC
Kinase AqueK221.AA Pkinase_Tyr 610-679 26 2.9e-09 32.02 Pfam 59-134 (270) Show / Hide 
Range on Protein: 610-679
Range on HMM: 59-134/270
Sequence Identity: 26% (20 aa)

NF-DHENICPFIGCIL-QGPT-IVGMMHEYCSHGSLYEVLRNP---NIVFDKQFRVLFATDIIKGLTYLHSHKLTH
.. .|.||  ..|... ||    . .  ||. ||.|.. ||..   .  .. .  . ....| ||. ||.|... |
QLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH
Kinase AqueK221.AA ILK 611-674 43 1.3e-08 25.4 In-house 53-118 (253) Show / Hide 
Range on Protein: 611-674
Range on HMM: 53-118/253
Sequence Identity: 43% (29 aa)

FDHENICPFIGCILQG--PTIVGMMHEYCSHGSLYEVL-RNPNIVFDKQFRVLFATDIIKGLTYLHS
| | |||| .||  |   |  |  . ..  ||||| ||    ..| |.   | || ||  |  .|||
FSHPNICPVLGCCNQPPAPNLV-IISQWMPHGSLYHVLHEATGVVVDHGQMVSFALDIARGMSFLHS
TyrKc AqueK221.AA TyrKc 571-794 17 2.2e-07 -103.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 571-794
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

LQEDSNIGE----------INGKIVKVHKMKMNISTLDLNLRKTMLQ----ILNF--DHENICPFIGCILQ--------GPTIVGMMHEYCSHGSLYEVL
.. .  .||           .   | | ..| .        |. ...      ..  .|.||  ..|...|        .|  . |  ||..||.| . |
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM--EYMPHGDLKDYL

RNPNIVFDKQFRVLFATDIIKGLTYLHSHKLTHGRLSSVTCVIGNLWKLKLTD-----YGPDA--------LHSMRTGSQGKK------------SSTQY
|..   .  .  . |...| .|  ||||... |  |    | .|.    | .|     .. |           .......||                 .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SYCSQDVSDDIYNFGLVLKEMSSR---QYII-----KDKVATIDELEYD------IE--------VPFEIKKLIESCISNNLLQRPTTERIKTCL
.  |     |.. || .. |. ..    |       ..    |  ..         .         | |. .....|   .  .||| . |. |.
TTKS-----DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
S_TKc AqueK221.AA S_TKc 571-794 16 3.8e-07 -72.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 571-794
Range on HMM: 1-231/231
Sequence Identity: 16% (42 aa)

LQEDSNIGEIN-GKIVKVHKMK---------MNISTLDLNLRKTMLQILNFDHENICPFIGCILQGPTIVGMMHEYCSH--GSLYEVLRNPNIV-----F
 .    ||.   ||  |... |         ..    .  .|   .     .|.||. .....    . . |  |||..  |.|...... .       |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DKQFRVLFATDIIKGLTYLHSHKLTHGRLSSVTCVIGNLWKLKLTDYGPDALHSMRTGSQGKKSSTQYSYC-----------SQDV-SDDIYNFGLVLKE
.      ..  |...| |.|||.  |  |      . .   .|..| |  ..               ...|           . .  . |.. .| .| |
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYE

MSSRQYIIKDKVATIDELEYDIEVPFEIKKLIESCISNNLLQRPTTERIKT---------CL
| ...        .....   |  . | | .|. |   .  .|||   . .          .
MLCGYPPFP----QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK221.AA Pkinase 609-679 23 2e-06 24.14 Pfam 55-131 (293) Show / Hide 
Range on Protein: 609-679
Range on HMM: 55-131/293
Sequence Identity: 23% (18 aa)

LNFDHENICPFIGCILQGPTIVGMMHEYCSHG----SLYEVLR-NPNIVF--DKQFRVLFATDIIKGLTYLHSHKLTH
....|.||. ....   .. |  |  ||| .|    .|.....   . .|  . .    ... |..|| |.||..  |
KRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH
Kinase AqueK221.AA TKL 765-794 30 0.002269 8.01 In-house 335-364 (364) Show / Hide 
Range on Protein: 765-794
Range on HMM: 335-364/364
Sequence Identity: 30% (9 aa)

VPFEIKKLIESCISNNLLQRPTTERIKTCL
.| ..|||.. | . .  .||. ..|.  |
CPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK221.AA RGC 758-796 22 0.049831 3.2 In-house 263-300 (300) Show / Hide 
Range on Protein: 758-796
Range on HMM: 263-300/300
Sequence Identity: 22% (9 aa)

ELEYDIEVPFEIKKLIESCISNNLLQRPT-TERIKTCLKR
. . .||.. .. .|.. | . .  .||.  ..|.. ||.
G-H-MIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase AqueK221.AA RGC 758-796 22 0.052321 3.2 In-house 263-300 (300) Show / Hide 
Range on Protein: 758-796
Range on HMM: 263-300/300
Sequence Identity: 22% (9 aa)

ELEYDIEVPFEIKKLIESCISNNLLQRPT-TERIKTCLKR
. . .||.. .. .|.. | . .  .||.  ..|.. ||.
G-H-MIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase AqueK221.AA TKL-Unique 766-794 34 0.257374 0.62 In-house 262-290 (290) Show / Hide 
Range on Protein: 766-794
Range on HMM: 262-290/290
Sequence Identity: 34% (10 aa)

PFEIKKLIESCISNNLLQRPTTERIKTCL
| |...||. |   .  |||. . | . |
PKEYRDLIQQCWHHDPSQRPSFDEIIHRL