Gene AqueK222 (A.queenslandica)

AqueK222

Species: A.queenslandica
Alias: AqueK222
External Links:
Annotation:

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
AqueK222.AA Protein None 850 None Fasta, JSON
AqueK222.kin_dom Protein Kinase Domain None 123 None Fasta, JSON

Protein domain

Protein domains of AqueK222.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK222.AA RGC 310-549 31 6.4e-70 238.61 In-house 1-300 (300) Show / Hide 
Range on Protein: 310-549
Range on HMM: 1-300/300
Sequence Identity: 31% (94 aa)

EGKTVAIKKLNYRS--RELQLTKTLRKEVMQIRSLDHANVCRFIGATLRSSE-----NVIILTEYCPKGSLNDVLQNDDIPLNWGFRFSFVTDISRGLAY
|| .|.|||.|.|   | . .|.. ..|. | | |.| |...|||. . . .     |..|..|||..||| |.| ||||.. | |..||..|| .|. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHSKRI-VHHRLMSTNCVIDDRWVVKITDYGI-----PSLRVC----------DSDRASEEGERRKRCLVFFPPE---ERDSTYYIP--------TLSGN
||.  | .| .| |.|||.|.||||||||.|.      ... .           |.   .. .. .. .  ..||   |....  ..        | .| 
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFSIILLETATRID-----PYSE-----ELFIDTTTGR-----------PRLPDLA-QEG---CPCPSTYQELIESCWDEVPGNRPS-FDQIKKSILR
|||| ||. | .||       |...     ||  .    .           |  |..  .|.     |. .  .|.. ||.| | .||. ||||.| . .
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase AqueK222.AA RGC 310-549 31 6.4e-70 238.61 In-house 1-300 (300) Show / Hide 
Range on Protein: 310-549
Range on HMM: 1-300/300
Sequence Identity: 31% (94 aa)

EGKTVAIKKLNYRS--RELQLTKTLRKEVMQIRSLDHANVCRFIGATLRSSE-----NVIILTEYCPKGSLNDVLQNDDIPLNWGFRFSFVTDISRGLAY
|| .|.|||.|.|   | . .|.. ..|. | | |.| |...|||. . . .     |..|..|||..||| |.| ||||.. | |..||..|| .|. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHSKRI-VHHRLMSTNCVIDDRWVVKITDYGI-----PSLRVC----------DSDRASEEGERRKRCLVFFPPE---ERDSTYYIP--------TLSGN
||.  | .| .| |.|||.|.||||||||.|.      ... .           |.   .. .. .. .  ..||   |....  ..        | .| 
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFSIILLETATRID-----PYSE-----ELFIDTTTGR-----------PRLPDLA-QEG---CPCPSTYQELIESCWDEVPGNRPS-FDQIKKSILR
|||| ||. | .||       |...     ||  .    .           |  |..  .|.     |. .  .|.. ||.| | .||. ||||.| . .
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase AqueK222.AA TKL 307-433 22 4.8e-30 105.37 In-house 12-200 (364) Show / Hide 
Range on Protein: 307-433
Range on HMM: 12-200/364
Sequence Identity: 22% (44 aa)

GVYEG----------KTVAIKKLNYRS-------------------------RELQLTKTLRKEVMQIRSLDHANVCRFIGATLRSSE------------
|.. |          |.||.||.. ..                            .. .....|.|....|.| |...|.|. ....             
GKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWG

NVIILTEYCPKGSLNDVLQNDDIPLNWGFRFSFVTDISRGLAYLHSKR--------IVHHRLMSTNCVIDDRWV--------------VKITDYGI
.  | .||||.||| ..|.       |  |.... ||.||..||||..        |.|  | | |. .|. |               .||.|.|.
QLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGL
Kinase AqueK222.AA TKL-Unique 307-437 29 3.3e-28 96.67 In-house 16-167 (290) Show / Hide 
Range on Protein: 307-437
Range on HMM: 16-167/290
Sequence Identity: 29% (45 aa)

GVYEGKTVAIKKLNY-RSRELQLTKTLRKEVMQIRSLD-HANVCRFIGATLR---SSENVIILTEYCPKGSLNDVLQ---------NDDIPLNWGFRFSF
|.. |. ||||...   . ..........||  .  |. |.|. ...|..     .  | .| .|||| |||.|||.         |. ..||.  | ..
GKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKM

VTDISRGLAYLHSKR--IVHHRLMSTNCVIDDR-----WVVKITDYGIPSLR
. ||..|. |||..   | |  | |.|  .| .     | .|| | |.. ..
AIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFN
Kinase AqueK222.AA DRK 311-432 31 9.4e-27 87.66 In-house 22-145 (258) Show / Hide 
Range on Protein: 311-432
Range on HMM: 22-145/258
Sequence Identity: 31% (39 aa)

GKTVAIKKLNYRSRE-LQLTKTLRKEVMQIRSLDHANVCRFIGATLRSSENVIILTEYCPKGSLNDVLQNDDIPLNWGFRFSFVTDISRGLAYLHSKR-I
|  ||.|.|     . . . . ...|.  .  | | |.| |.|. . ... . | .|| |.|||  .| .. | . |. . .   |. .|. |||.   |
GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPD-ICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPI

VHHR-LMSTNCVIDDRWVVKITDYG
. || | | |  .|. | ||. |.|
IIHRDLKSHNLLVDEHWQVKVADFG
Kinase AqueK222.AA MLK 307-433 25 1.4e-26 89.33 In-house 18-179 (291) Show / Hide 
Range on Protein: 307-433
Range on HMM: 18-179/291
Sequence Identity: 25% (42 aa)

GVYEGKT-----VAIKKLNYRSRELQLT----KTLRKEVMQIRSLDHAN----VCRFIGATLRSSENVIILTEYCPKGSLNDVLQN-------------D
|.. .|.     ||.|. . | .. . |    . ...|... | |.| |    ...| |. |..  .. |..|||..|||..|| .              
GRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKN

DIPLNWGFRFSFVTDISRGLAYLHS-KR--IVHHRLMSTNCVIDD------RWVVKITDYGI
|.    .. ... ....||..|||| ..  |.|. | | | .||.        ..||.| |.
DRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGT
Kinase AqueK222.AA TK 308-432 13 1.5e-23 75.12 In-house 18-296 (486) Show / Hide 
Range on Protein: 308-432
Range on HMM: 18-296/486
Sequence Identity: 13% (39 aa)

VYEG-------------------------------KTVAIKKLN-YRSRELQLTKT--------------LRKEVMQIRS--LDHANVCRFIGATLRSS-
||.|                                .||.| |    . . .  .               .  | .. ..  ..| |. |..|. ...  
VYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEP

----------ENVIILTEYCPKGS----LNDVLQNDDIP-------------------------------------------------------------
          | ..|..||.|.|.    | | |.. . .                                                             
KPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDL

--------------LNWGFRFSFVTDISRGLAYLHSK------RIVHHRLMSTNCVIDDRWV-----------VKITDYG
              |.   .  .  .|..|..|||||      ..||  |   || .... |           .||.|.|
LQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFG
Kinase AqueK222.AA Dicty4 311-433 35 4.8e-22 70.47 In-house 22-160 (277) Show / Hide 
Range on Protein: 311-433
Range on HMM: 22-160/277
Sequence Identity: 35% (50 aa)

GKTVAIKKL---NYRSRELQLTKTLRKEVMQIRSLDHANVCRFIGATL--RS-SENVIILTEYCPKGSLNDVLQN------DDIPLNWGFRFS---FVTD
|| ||.|||   |  ..|  |.  .||||    .. | |.| | || .  || .. . | |||.|||.|  .| .      . |.| |. . .      |
GKEVAVKKLNNHNQNFDENMLNE-FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFD

ISRGLAYLHS--KRIVHHRLMSTNCVIDDRWVVKITDYGI
. ||...||.   .|.|  | | |  .|. |.||..| |.
AARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGL
Kinase AqueK222.AA Pkinase 310-410 25 2.5e-21 76.47 Pfam 23-131 (293) Show / Hide 
Range on Protein: 310-410
Range on HMM: 23-131/293
Sequence Identity: 25% (28 aa)

EGKTVAIKKLNYRSRELQLTKTLRK--EVMQIRSLDHANVCRFIGATLRSSENVIILTEYCPKG----SLNDVLQ-NDDIPL--NWGFRFSFVTDISRGL
.||.||.|....|... .  .|.|.  |.   ..|.| |..|....  . . .. . .|||..|    .| |...  .. ..   .    .... | |||
TGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGL

AYLHSKRIVH
.|.||..|.|
EYCHSMGIIH
Kinase AqueK222.AA TK-Unique 312-433 26 5.2e-21 69.27 In-house 31-179 (294) Show / Hide 
Range on Protein: 312-433
Range on HMM: 31-179/294
Sequence Identity: 26% (39 aa)

KTVAIKKLNYRSRELQLTKTLRKEVMQIRSLDHANVCRFIGATLRSSENVIILTEYCPKGSLNDVLQ----------------------NDDIP---LNW
| ||.|.|. ......  . |..  |     || |. ...|.. .|.|.. |. ||||.|.| . |.                      .|. .   .. 
KCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISP

GFRFSFVTDISRGLAYLHS--KRIVHHRLMSTNCVIDDRWVVKITDYGI
.. ..|  .| .|..||.|  |.|||..| . |. . .. |.||.|.|.
KDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGM
Kinase AqueK222.AA Dicty5 307-433 31 6e-20 65.35 In-house 18-150 (260) Show / Hide 
Range on Protein: 307-433
Range on HMM: 18-150/260
Sequence Identity: 31% (42 aa)

GVYEGKTVAIKKLNYRS-RELQLTKTLRKEV--MQIRSLDHANVCRFIGATLRSSENVIILTEYCPKGSLNDVLQNDDI----PLNWGFRFSFVTDISRG
|.| |. |||| .         .     .||  | |   || |. |. ||  .      ..|||| .||| . |         |. .. . ..  || ..
GIYKGMDVAIKVYSQENCMCFDW-NEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQS

LAYLHSKRIVHHRLMSTNCVIDDRWVVKITDYGI
. .|||. |.|  | | |  |  .| .|| |.|.
MRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGT
Kinase AqueK222.AA Pkinase_Tyr 307-410 24 1.6e-19 66.72 Pfam 18-134 (270) Show / Hide 
Range on Protein: 307-410
Range on HMM: 18-134/270
Sequence Identity: 24% (29 aa)

GVYE------GKTVAIKKL--NYRSRELQLTKTLRKEVMQIRSL-DHANVCRFIGATLRSSEN--VIILTEYCPKGSLNDVLQND---DIPLNWGFRFSF
|..       . .||.|.|  .. .... . . . .|.   ..| .| |. |..|. .. .|   ..| .||.|.|.| | |..    . ||.     ..
GTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQM

VTDISRGLAYLHSKRIVH
 ..|..|..||.||...|
CWQIAKGMEYLESKNCIH
Kinase AqueK222.AA TKL 476-547 30 1.7e-19 66.85 In-house 272-364 (364) Show / Hide 
Range on Protein: 476-547
Range on HMM: 272-364/364
Sequence Identity: 30% (28 aa)

VYSFSIILLETATRIDPYSEELFID-----------TTTG----RPRLPDLAQE------GCPCPSTYQELIESCWDEVPGNRPSFDQIKKSI
|||| |.| | .||  ||... ...              .    || .|.  |.        .||  . .|.. |||. | .||||..|.| .
VYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
TyrKc AqueK222.AA TyrKc 296-547 23 5.2e-15 19.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 296-547
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

LNGNRQIF------IPTGVYEGKTVAIKKLNYRSRELQLTKTLRKEVMQIRSL--DHANVCRFIGATLRSS------ENVIILTEYCPKGSLNDVLQNDD
.  ....       .  |..   .||.|.|.  .      . ...|    ..|  .| |. |..|. . ..      | . |..||.|.|.|.| |..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

IPLNWGFRFSFVTDISRGLAYLHSKRIVHHRLMSTNCVIDDRWVVKITDYGI-PSLRVC-------DSDRASEEGERRK-RCLVFFPPEERDSTYYIPTL
  |..    || ..|..| .|||||...|  |   || .... .|||.| |    .          |  |..|.. ..    .   .||     |.. | 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTT

SGNVYSFSIILLETATRID-PYSE---------ELFIDTTTG-RPRLPDLAQEGCP-----CPSTYQELIESCWDEVPGNRPSFDQIKKSI
   |.|| . . |  |. . ||..         |.. .  .| |.. |. .    |     ||.   .....||.| | .||.| .|.. .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
S_TKc AqueK222.AA S_TKc 282-548 15 8.7e-12 -4.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 282-548
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)

GETDNVSGQGS------VFNLNGNRQIFIPTGVYEGKTVAIKKLNYRSRELQLTKTLRKEVMQIRSLDHANVCRFIGATLRSSENVIILTEYCPK--GSL
 |  .. |.|.      . . .             |. ||||...         ...|.|.   .. .| |.......     ... . .|||.   |.|
YEILRKIGKGAFGKVYKCRHKK------------TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDL

NDVLQNDDIP-----LNWGFRFSFVTDISRGLAYLHSKRIVHHRLMSTNCVIDDRWVVKITDYGIPSLRVCDSDRASEEGERRKRCLVFFPPEERDSTYY
 |....   .     ..     ...  | ..|.|.||..|.|  |   |  .|.  ..||.| |.  .                  . . .||       
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----G

IPTLSGNVYSFSIILLETATRIDPYSEELFIDTTTGRPRLPDLAQEGCPCPSTYQELIESCWDEVPGNRPSFDQIKK--------SIL
  . .  ..|. .|| | ...  |..             .  . .  .  ..   ..|. |..  | .||.  .. .          .
YGKCKCDWWSCGCILYEMLCGYPPFP------------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK222.AA Dicty5 476-551 34 1.9e-11 35.65 In-house 186-260 (260) Show / Hide 
Range on Protein: 476-551
Range on HMM: 186-260/260
Sequence Identity: 34% (28 aa)

VYSFSIILLETATRIDPYSEELFIDTTT-----GRPRLPDLAQEGCPCPSTYQELIESCWDEVPGNRPSFDQIKKSILRMN
|||| |.| |  ||  || .   ..        .|| .|        ||...  ||..|| . | |||||  | | . .. 
VYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGERPTIPK------DCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase AqueK222.AA TK 467-547 20 1.8e-10 30.56 In-house 368-486 (486) Show / Hide 
Range on Protein: 467-547
Range on HMM: 368-486/486
Sequence Identity: 20% (24 aa)

YYIPTLSGNVYSFSIILLETATRI-DPYS--------------EELFIDTTTGRP-----------RLPDLAQEGCPC------------PSTYQELIES
| . |    |.|| . . |  |.   ||               .|..   ..|.            |..  . ..||             |  |..|. .
YGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQ

CWDEVPGNRPSFDQIKKSI
||.. |  ||.|.|... .
CWHYDPEDRPTFSQLHEQL
Kinase AqueK222.AA TKL-Unique 518-547 46 1.7e-09 29.81 In-house 261-290 (290) Show / Hide 
Range on Protein: 518-547
Range on HMM: 261-290/290
Sequence Identity: 46% (14 aa)

CPSTYQELIESCWDEVPGNRPSFDQIKKSI
||  |..||. ||.  | .|||||.| ...
CPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK222.AA MLK 518-547 40 3.5e-09 28.12 In-house 262-291 (291) Show / Hide 
Range on Protein: 518-547
Range on HMM: 262-291/291
Sequence Identity: 40% (12 aa)

CPSTYQELIESCWDEVPGNRPSFDQIKKSI
||    .|.. ||.. |..||||.|| .  
CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK222.AA Dicty4 518-550 44 4.5e-09 26.59 In-house 244-277 (277) Show / Hide 
Range on Protein: 518-550
Range on HMM: 244-277/277
Sequence Identity: 44% (15 aa)

CPSTYQELIESCWDEVPGNRPSFDQIKKS-ILRM
||  . .||. |||. | .|||| .| .  ||  
CPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK222.AA TK-Unique 518-547 41 2.8e-08 24.79 In-house 264-294 (294) Show / Hide 
Range on Protein: 518-547
Range on HMM: 264-294/294
Sequence Identity: 41% (13 aa)

C-PSTYQELIESCWDEVPGNRPSFDQIKKSI
| . .  .|..||| ..|  ||||.|||. .
CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK222.AA DRK 518-550 36 2e-06 17.92 In-house 227-258 (258) Show / Hide 
Range on Protein: 518-550
Range on HMM: 227-258/258
Sequence Identity: 36% (12 aa)

CPSTYQELIESCWDEVPGNRPSFDQIKKSILRM
||  |  |.  ||.| |  |||.... . .|  
CPPKYIQLMNDCWNEDPQHRPSMQECLE-RLEA
Kinase AqueK222.AA DRK 476-493 66 2e-05 14.35 In-house 185-202 (258) Show / Hide 
Range on Protein: 476-493
Range on HMM: 185-202/258
Sequence Identity: 66% (12 aa)

VYSFSIILLETATRIDPY
|||| |.| | .|| |||
VYSFAIVLWECVTRQDPY
Kinase AqueK222.AA Dicty4 476-495 52 3.1e-05 13.61 In-house 200-220 (277) Show / Hide 
Range on Protein: 476-495
Range on HMM: 200-220/277
Sequence Identity: 52% (11 aa)

VYSFSIILLETATRIDPYS-E
||||.|.| | .|| .||. .
VYSFGIVLWEILTRQEPYQKH
Kinase AqueK222.AA Pkinase_Tyr 518-547 33 3.7e-05 18.11 Pfam 241-270 (270) Show / Hide 
Range on Protein: 518-547
Range on HMM: 241-270/270
Sequence Identity: 33% (10 aa)

CPSTYQELIESCWDEVPGNRPSFDQIKKSI
||    .|. .||.. | .||.| .|   .
CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK222.AA Pkinase 476-547 15 0.000286 16.18 Pfam 195-293 (293) Show / Hide 
Range on Protein: 476-547
Range on HMM: 195-293/293
Sequence Identity: 15% (15 aa)

VYSFSIILLETATRIDPYSEE--------LFIDTTTGRPRLPDLAQEGCPCP-----------------STYQELIESCWDEVPGNRPSFDQIKKS--I
..|. .|| | ...  |....        ...   ...|.|.   .. |. .                 .. ...|..|..  |  ||...||...  .
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK222.AA TKL-Unique 476-495 46 0.031467 3.88 In-house 211-236 (290) Show / Hide 
Range on Protein: 476-495
Range on HMM: 211-236/290
Sequence Identity: 46% (12 aa)

VYSFSIILLETATRID------PYSE
||||.|.| | |||        ||..
VYSFGIVLWEIATRKITKTYKKPYQG
CYCc AqueK222.AA CYCc 585-787 43 6.4e-105 355.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 585-787
Range on HMM: 1-231/231
Sequence Identity: 43% (102 aa)

IEQKKTQQLLYTMLPQAVADELRQGR-PASAKQYSSVTIYFSDIVGFTTLAGASSPMEVVTFLNELYSTFDDILDKFD-----VYKVETIGDAYMVVSGV
.|..|...||. |||. ||..|.||| |. .. |..|||.|.||||||.|. ...||.||..||..|. ||.|.|...     .|||||||||||||||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PRVNGD-------------------KHAGEIARMALQLLAASKIFVIPHK----PNTELKIRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESNSE
|..|..                    || .|| .||  . ..|.| ..|.    |.. |..|||||.|||..||||..|||||.||||||.||||||...
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

AMKIHCSNDTAQLLKKVGGFQLECRGTLEIKG
...||.| .| ..| .  .|.. ..|. |...
PGQIHVSEETYWCLCLD-QFERRRCGQFEFEP
Guanylate_cyc AqueK222.AA Guanylate_cyc 612-798 42 1.4e-92 318.71 Pfam 1-214 (214) Show / Hide 
Range on Protein: 612-798
Range on HMM: 1-214/214
Sequence Identity: 42% (91 aa)

ASAKQYSSVTIYFSDIVGFTTLAGASS----PMEVVTFLNELYSTFDDILDKF--DVYKVETIGDAYMVVSGVPRV-----NGDKHAGEIARMALQLLAA
  |..| .|||.|.|||||| .. ..|    ||..|..||..|..||...|..  ..|||.||||.||.|||.|       ..  ||  .| ||| .. .
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

SKIFVIPHKPNTE-----LKIRIGIHSGPVCAGVVG--LKMPRYCLFGDTVNTASRMESNSEAM--KIHCSNDTAQLLKKVGGFQLEC----RGTLEIKG
 . . ..|.. ..     ...|||||.|||.|||.|  ..|||||..|||||.||||||....   ||| |. |...||. ..|| ||    ||  ..||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGQ---MTTWWLKG
||.   |.|..|.|
KGKMGEMETYFLHG
HNOBA AqueK222.AA HNOBA 559-606 38 6e-06 22.98 Pfam 190-234 (234) Show / Hide 
Range on Protein: 559-606
Range on HMM: 190-234/234
Sequence Identity: 38% (19 aa)

DTMMKMME-KYSKHLEALVGERTQELIIEQKKTQQLLYTMLPQAVADEL
. .|. || . .. ||    . ..||  | ||| .||| |.|  ||..|
YKLMCRMEQQLKDKLE----QMHRELEEEKKKTDDLLYSMFPKSVANRL