AqueK230

Species: A.queenslandica
Alias: AqueK230
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: KHS

Sequence

Name Sequence Type Origin Length Description Download
AqueK230.AA Protein None 829 None Fasta, JSON
AqueK230.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of AqueK230.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK230.AA KHS 21-87 56 5.9e-37 121.74 In-house 1-67 (258) Show / Hide
Range on Protein: 21-87
Range on HMM: 1-67/258
Sequence Identity: 56% (38 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPGEDFNIIQQEILILSECKHANIVGYLGSYLR
.||....||||||.||||. .....| |.|.||.|||.|| .|||||... .|.|.|||.| |||||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLR

Kinase AqueK230.AA STE20 21-87 42 4.5e-28 99.6 In-house 1-75 (288) Show / Hide
Range on Protein: 21-87
Range on HMM: 1-75/288
Sequence Identity: 42% (32 aa)

FELVKQIGSGTYGEVYKAKLVKTGQL----CALKIIKIEPG----EDFNIIQQEILILSECKHANIVGYLGSYLR
.||...||.|.||.||||  ..||..    .| |....|.     .... ||.||.|...||| ||| |.||||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLK

Kinase AqueK230.AA STE 21-87 27 7.5e-25 84.76 In-house 1-101 (359) Show / Hide
Range on Protein: 21-87
Range on HMM: 1-101/359
Sequence Identity: 27% (28 aa)

FELVKQIGSGTYGEVYKAKLVK---------------TGQLCALKIIKIEPG-----------------EDFNIIQQEILILSECK--HANIVGYLGSYL
.|....||.|..|.||||. .|               ||...| |....|.                  |... |..|| |...|.  | ||| |.|.|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

R
.
K

Kinase AqueK230.AA MST 21-86 42 4.6e-20 60.41 In-house 1-64 (254) Show / Hide
Range on Protein: 21-86
Range on HMM: 1-64/254
Sequence Identity: 42% (28 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPGEDFNIIQQEILILSECKHANIVGYLGSYL
|..|  .| | || ||||   .||.. | |.....  ||.. |  || |...||  .||.| |||.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN--EDLQEIIKEISIMQQCKSKYIVKYYGSYF

Kinase AqueK230.AA YSK 21-87 45 4.9e-20 56.7 In-house 1-68 (257) Show / Hide
Range on Protein: 21-87
Range on HMM: 1-68/257
Sequence Identity: 45% (31 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPGED-FNIIQQEILILSECKHANIVGYLGSYLR
|     || | .|||||.  ..|..  | |||  |  ||    ||||| .||.|.  .|  |.||||.
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLK

Kinase AqueK230.AA PAKA 21-86 41 6.9e-18 59.45 In-house 1-68 (260) Show / Hide
Range on Protein: 21-86
Range on HMM: 1-68/260
Sequence Identity: 41% (28 aa)

FELVKQIGSGTYGEVYKAKLVKTGQL--CALKIIKIEPGEDFNIIQQEILILSECKHANIVGYLGSYL
.. ...|| |  ||||.|. .||.|   .| | ....     . |  |||.. |||| ||| |. |||
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYL

Kinase AqueK230.AA Pkinase 21-87 33 7.2e-17 60.73 Pfam 1-71 (293) Show / Hide
Range on Protein: 21-87
Range on HMM: 1-71/293
Sequence Identity: 33% (24 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPGEDFNIIQQ-----EILILSECKHANIVGYLGSYLR
......||||..|.|||.. ..||.. |.|||| . .|. .  |.     || |. ...| ||| ..... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED

Kinase AqueK230.AA MSN 21-87 41 3e-16 49.92 In-house 1-67 (265) Show / Hide
Range on Protein: 21-87
Range on HMM: 1-67/265
Sequence Identity: 41% (28 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPGEDFNIIQQEILILSECKHANIVGYLGSYLR
||||. .| ||||.||| . |||||| |.|.....  |. .| |   ..     | ||. | | ...
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIK

Kinase AqueK230.AA STE11 21-84 32 2.7e-14 48.32 In-house 1-78 (303) Show / Hide
Range on Protein: 21-84
Range on HMM: 1-78/303
Sequence Identity: 32% (25 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPGE--------DFNI------IQQEILILSECKHANIVGYLGS
. . . ||.|..| |||.  |.||.| | | |.|.. .          .       ||.|| ...  .| ||| |.|.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGC

Kinase AqueK230.AA SLK 21-85 40 5.9e-14 43.35 In-house 1-65 (259) Show / Hide
Range on Protein: 21-85
Range on HMM: 1-65/259
Sequence Identity: 40% (26 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPGEDFNIIQQEILILSECKHANIVGYLGSY
.|..  .| | .| ||||.   .... | |.|.|. .|. .    || ||||||| |||. ...|
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAY

Kinase AqueK230.AA Pkinase_Tyr 21-83 26 1.8e-10 36.11 Pfam 1-71 (270) Show / Hide
Range on Protein: 21-83
Range on HMM: 1-71/270
Sequence Identity: 26% (19 aa)

FELVKQIGSGTYGEVYKAKLV----KTGQLCALKIIKIEPGED---FNIIQQEILILSEC-KHANIVGYLG
 .. |..|.| .|||||...     .|.. .| |..|    ..        .|. |...  .| ||| ..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYG

Kinase AqueK230.AA STE7 21-83 30 9.5e-10 32.01 In-house 1-66 (288) Show / Hide
Range on Protein: 21-83
Range on HMM: 1-66/288
Sequence Identity: 30% (20 aa)

FELVKQIGSGTYGEVYKAKLVKTGQLCALKIIKIEPG--EDFNIIQQEILILSECK-HANIVGYLG
.| ....|.| || |||. ....|.. |.| |. .    |. . | .|. .| .|. . .||.. |
LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYG

Kinase AqueK230.AA KHS 227-278 59 2.3e-23 75.31 In-house 207-258 (258) Show / Hide
Range on Protein: 227-278
Range on HMM: 207-258/258
Sequence Identity: 59% (31 aa)

ALYLMTKRNFRPPTLQHKNKWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
||.|||| ||.||.|. |.|||..||.|. .|| |.|| ||.|. ||.|.||
ALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV

Kinase AqueK230.AA STE20 227-278 46 1.9e-20 71.7 In-house 235-288 (288) Show / Hide
Range on Protein: 227-278
Range on HMM: 235-288/288
Sequence Identity: 46% (25 aa)

ALYLMTKRNFRPPTLQH--KNKWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
|.....| .  ||||..  ..||| .||||... | |||. || |..||||.|.
AMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI

Kinase AqueK230.AA STE 227-278 26 3.8e-18 60.75 In-house 276-359 (359) Show / Hide
Range on Protein: 227-278
Range on HMM: 276-359/359
Sequence Identity: 26% (22 aa)

ALYLMTKRN-------------FRPPTLQH-----------------KNKWSNNFHDFLSQALKKDPKIRPNADDLLK--HEFV
|...... .             . ||.|..                 . ||| .|.||... |.|||. ||.|..|||  |.|.
AMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase AqueK230.AA YSK 227-278 40 3e-15 42.0 In-house 209-257 (257) Show / Hide
Range on Protein: 227-278
Range on HMM: 209-257/257
Sequence Identity: 40% (21 aa)

ALYLMTKRNFRPPTLQHKNKWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
.. |  |.|  ||.|. ....| .| .|    |.|||. || |..||||.|.
VMFLIPKNN--PPKLE-GRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI

Kinase AqueK230.AA PAKA 227-278 35 3.5e-15 49.84 In-house 211-260 (260) Show / Hide
Range on Protein: 227-278
Range on HMM: 211-260/260
Sequence Identity: 35% (19 aa)

ALYLMTKR-NFRPPTLQHKNKWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
|.|| ..      | .....||| .|.|||.. |..|.. |. |..||.|.| 
AMYLIATNGK---PDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL

Kinase AqueK230.AA SLK 238-278 43 3.6e-15 47.5 In-house 219-259 (259) Show / Hide
Range on Protein: 238-278
Range on HMM: 219-259/259
Sequence Identity: 43% (18 aa)

PPTLQHKNKWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
||||.   .||..|.||| ..|.|||. |. ...|..|..|
PPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV

Kinase AqueK230.AA MST 238-278 41 4.2e-15 44.39 In-house 214-254 (254) Show / Hide
Range on Protein: 238-278
Range on HMM: 214-254/254
Sequence Identity: 41% (17 aa)

PPTLQHKNKWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
|||..   .|| .| ||... | |.| .|. | .||.|.|.
PPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI

Kinase AqueK230.AA STE7 235-278 41 8e-12 39.63 In-house 246-288 (288) Show / Hide
Range on Protein: 235-278
Range on HMM: 246-288/288
Sequence Identity: 41% (19 aa)

NF-RPPTLQHKNKWSNNFHDFLSQALKKDPKIRPNADDLLK-HEFV
|.  ||.|    |.|  | || .. |.|||. ||. ..|.| |.|.
NENPPPRLP---KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI

Kinase AqueK230.AA STE11 252-278 48 6.8e-10 32.25 In-house 277-303 (303) Show / Hide
Range on Protein: 252-278
Range on HMM: 277-303/303
Sequence Identity: 48% (13 aa)

HDFLSQALKKDPKIRPNADDLLKHEFV
.|||.. ...||| ||.|..||.| |.
RDFLRHCFEHDPKKRPTANQLLQHPFI

Kinase AqueK230.AA MSN 238-278 41 9.2e-10 28.16 In-house 226-265 (265) Show / Hide
Range on Protein: 238-278
Range on HMM: 226-265/265
Sequence Identity: 41% (17 aa)

PPTLQHKNKWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
||.|.   |||  ||.|. . | |. . ||.....||| |.
PPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI

Kinase AqueK230.AA Pkinase 246-278 42 7e-06 21.83 Pfam 261-293 (293) Show / Hide
Range on Protein: 246-278
Range on HMM: 261-293/293
Sequence Identity: 42% (14 aa)

KWSNNFHDFLSQALKKDPKIRPNADDLLKHEFV
.|| .. ||..  |.|||| ||.|...|.|...
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

CNH AqueK230.AA CNH 510-805 19 4.9e-52 180.12 SMART 1-375 (375) Show / Hide
Range on Protein: 510-805
Range on HMM: 1-375/375
Sequence Identity: 19% (74 aa)

CATSWTHPHNQNY----YVLLGAEEGLFSLQANTQ----QDPVMEQVSPRS---CHWLRVVENVLIWLSGTNHMISMTNLIQLFQ-------------SE
|...|.||.        ..|.|.|.|...|  |.|    ..  .|.  .|    | |. ...|.|. .|| .  . . .|. |||             ..
CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPHIQDHM

SQKAPGHRNRSHTSKIHDSKG-CYKCSI-ARNPFSDQRYLLAAVPKGILVM-QWYQPRHAFMHVK--------------LFECSLPSPLNMFEAFVIEND
.. ..  |  . | || | || | .| . .... .   .| .|... . .  |||.| |.|| .|               |  ....|...|. |.... 
CNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDSF

EYPSVCVGVRE-----SEGGNVQFN-------------AININSNSCWFDSFSND------EIIELQQLEK------DTIFVASQFCAKFVDLNGTMKPS
|.|..|.|.       ...  ||..              .| |. |.|| ...        . .. .|..       |..... . ...||.. |  ...
ERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYG-SEWR

GKQASQIYFDKKTESMVYLQNCVLSFHKHGMQGKSLITQQV-TAEVADS----SKVFHLLG----SHGTIIIETKQ
 . .. . ...  |. .|... .. |...|.|. .. | .. | ...|     .. |.||.    ....|....  
RWRNPILHWEFMPEYFAYHYPYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP

CNH AqueK230.AA CNH 515-795 17 1.4e-46 165.87 Pfam 1-336 (336) Show / Hide
Range on Protein: 515-795
Range on HMM: 1-336/336
Sequence Identity: 17% (62 aa)

THPHNQNYYVLLG-AEEGLFSLQA----NTQQDPVMEQVSPRSCHWLRVVE--NVLIWL--SGTNHMISMTNLIQLFQSESQKAPGHRNRS---------
..|     ..|.| ..|||. .      . . .  ..| ..| .... |.|  |.|| .  ...|. . . .| .|.|.| |... |....         
VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSRRVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRIERI

------HTSKIHDSKGCYKCSIARNPFSDQRYLLAAVPK-----GILVMQWYQPRHAF-------------MHVKL-FECSLPSPL-NMFEAFVIENDEY
       . |..|.|.| .....||.....|.| .||..     .|....||.|.. |             ....  |. .|| |. ..|.  . . .|.
MPRKFAMWQKLPDTKHCHFFCWIRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLP-PMTECFSMHWLP-QEK

PSVCVGVRESEGGNVQFNAININ--SNSCWFDSFSN----DEI---------IELQQLEKD-TIFVASQFCAKFVDLNGTMKPSGKQASQIYFDKKTESM
|..|||.      ...| ..|..  . ..|. ....     ..         |   ....| ..... . |...|...|  .... . ..| .. . .|.
PKLCVGC------QKGFHIVNLDGTGQPWWLHDPADHSVQQDFMARRENCKPICMHRINDDEEFLLCYDECCVYVNKQGWPRSRK-HDWEIMWEGMPQSF

VYLQNCVLSFHKHGMQGKSLITQ-QV---TAEVADSSKVFHLLGS
.......| ||...... .. |  ..   . .... .  | ..||
ACCYPYLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS