Gene AqueK234 (A.queenslandica)

AqueK234

Species: A.queenslandica
Alias: AqueK234
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: NinaC

Sequence

Name Sequence Type Origin Length Description Download
AqueK234.AA Protein None 1348 None Fasta, JSON
AqueK234.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of AqueK234.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK234.AA STE20 53-319 46 7.29999999999e-137 460.99 In-house 1-288 (288) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-288/288
Sequence Identity: 46% (135 aa)

WELVEKIGKGNYGVVFKGRNRKTGKI----GAVKIMDAVL-----EKEEDIQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGGSVTDL
.||.||||.|.||.|.|.....||..     |.|.|.        ...|||| ||.. ...  |.|||  || |||  ..  ..||||||.|.|||.||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC-DDELWIVMEYCGGGSLTDI

VKKIKDKGD-----TLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSH----AYG-RRRTAIGTPYWMAPEVIACEH
.|.   .|      ...|. ||||..||| || |||.|.|.|||||..|.|.| ||.. |.||| .| ...    . . .| | .|||||||||||.|..
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

QLDYDYDVRADVWSLGITAIEMVDGVPPLFGENPIRALYKIP--KNPPPKLQN--PTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
. | .|| ..|.||||||||||..| ||.| ..| ||...||  .||||.|..  |.|||  ...|..|||.|| | |||. ||  |. |
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK234.AA NinaC 53-319 50 1e-136 460.46 In-house 1-267 (267) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-267/267
Sequence Identity: 50% (136 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKEEDIQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGGSVTDLVKKIKDKGD
|| .| |||| || |||  |.. |.| ||||.. . . .|.| || |. ..|..| |.|  ||.| |  ..  .|||.||| |.||||||.||..   | 
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

TLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVWSLGITA
 ..|..||||||| . ||  ||.| ..|||.|| |.|.| .|...|.|||. | ..   .|| |..|||.|||||||||. |.| |||.|.|||||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
||. || ||..   |.||..||| ||||.|  |..|.  .| || .|| ||.|.||.  ..  |  |
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase AqueK234.AA MSN 53-319 52 2.7e-121 402.38 In-house 1-265 (265) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-265/265
Sequence Identity: 52% (141 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKEEDIQAEINVFQKYSSHENIVDCYGLYLKRQEN-STEQLWIVMEHCAGGSVTDLVKKIKDKG
.|||| .|.| || |.|||  |||.. |.|.||.  . ||.|. |||. .||| | ||.  || ..|..     .|||.||| |. ||||||||.   ||
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMT--KG

DTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVWSLGIT
..| || ||||  |.| || .|| . ..||||||||||.| .  ..|.|||..| ...  ||| | ||||||||||||||. . |  || |.|.||.|||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
|||| .| |||    |.|||. ||.||||||.   |||   ..|. |||.|... ||...|.  |  |
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase AqueK234.AA STE 53-319 33 5.9e-116 391.54 In-house 1-359 (359) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-359/359
Sequence Identity: 33% (122 aa)

WELVEKIGKGNYGVVFKGRNRK---------------TGKIGAVKIMDAVL------------------EKEEDIQAEINVFQKYSS-HENIVDCYGLYL
||..||||||..|.|.|..|.|               ||.| |.|.|.                     |....|. ||.. .|... |.||| .|| |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KRQ--ENSTEQLWIVMEHCAGGSVTDLVKKIKDKGDTLS----------EDIIAYILHEVLAG-LVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAA
|    ... ..|||.||...|||..|..|. . .|..|.          |..||||....| | | |||...|.|||||..|.|.     . |.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

AVSH---------------AYG-RRRTAIGTPYWMAPEVIACEHQLDY--DYDVRADVWSLGITAIEMVDGVPPLFGENPIRALYKIPKN----------
 ...                 . .| | .||| ||||||| .. |  .  .||...|.||||.|.|||..| ||.. ..| ||.. ||.|          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----PPPKLQN-----------------PTKWSIYLNQFIAKCLVKDFERRPTSGQLTM--HELI
     |||.|..                 |.|||  ...||.|||.|| . |||. ||    |. |
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK234.AA YSK 53-319 43 4.6e-104 314.26 In-house 1-257 (257) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-257/257
Sequence Identity: 43% (118 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKE----EDIQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGGSVTDLVKK--
.   |.||.|..|.|.|| ...|... |.|| |  ||.     |||| ||..     |  .|   || |||        |||.||.|.|||. || |.  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIID--LEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYLK-----DTKLWIIMEYCGGGSCLDLMKPKY

IKDKGDTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVW
.      . |  || ||.|.| || ||| ..  |||||  |||.. .| . | |||.|. .     .| | .||||||||||| .|      ||  ||.|
V----GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEV---SYYDFKADIW

SLGITAIEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
||||||.||  | ||.    | |..  ||||.||||.   ..|  .  |.. ||.|| | ||.  .|  |. |
SLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK234.AA MST 53-319 44 1.3e-101 323.78 In-house 1-254 (254) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-254/254
Sequence Identity: 44% (119 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKE-EDIQAEINVFQKYSSHENIVDCYGLYL--KRQENSTEQLWIVMEHCAGGSVTDLVKKIKD
 ..|||.| |.||.|.|  ...|||| |.|..    .   ..|  ||.  |   | ..||  || |.  | ..     .|||||.|..||| |.. || .
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQQCKS-KYIVKYYGSYFDAKNNH-----CWIVMEYCGMGSVCDIM-KITQ

KGDTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVWSLG
.  ||.|. || ||  .| || |||.| ..|||||  | |.  .|   | ||| ..  ..  . | | ||||||||||||         ||  || ||||
R--TLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLG

ITAIEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
||||||  | ||..   | ||. .||..|||....|..||  .| |..|||.|. | |.|. ||  |. |
ITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase AqueK234.AA S_TKc 53-319 31 3.1e-85 290.41 SMART 1-231 (231) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKEEDIQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAG--GSVTDLVKKIKDK
.|...||||| .|.|.|.|..|||.| |.||..      |.|. ||.. .|   |.||| .|. .        . |..|||.| |  |.. |. || . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

G--DTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDV-RADVWS
|    ..|  ......... .| |.|...|.|||.| .|.|..   .| ..|||.|. .       .| .|||..|||||.         |.  ..|.||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWWS

LGITAIEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTM-------HELI
.|.. .||. | ||      . ...|. .            |  . .|| |||.|| |.|||  ..         |. .
CGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK234.AA SLK 53-319 41 1.2e-82 278.58 In-house 1-259 (259) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-259/259
Sequence Identity: 41% (110 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKE-EDIQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGGSVTDLVKKIKDKG
||..  .| | .| | | ... .... | |...   | | ||   ||..  .   | |||. |. |        ..||...|.|.|| |  ..  .   .
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYY-----YDNKLWMMIEFCDGGAVDNIMVEL---E

DTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVWSLGIT
 .| || |.|. .... .| .||.|...|||.|  |.||| || .|| |||..|   |   .| | |||||||||||..||   |  || .||.||||||
HPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGIT

AIEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
 ||| .. ||    ||.| | || |  ||.|..| .||   . |. |||||| . |.|. ||  |. .
LIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase AqueK234.AA PAKA 53-319 38 1.9e-82 280.24 In-house 1-260 (260) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-260/260
Sequence Identity: 38% (104 aa)

WELVEKIGKGNYGVVFKGRNRKTGKI--GAVKIMDAVLEKEE-DIQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGGSVTDLVKKIKD
 . .||||.|  | |... |.||..    |.| |.   .     |  || |  | . |.|||. .  ||       ..||.|||  .||. ||....  .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVM-KECKHKNIVNYIDSYLV-----DDELWVVMEYMEGGCLTDVITQCCN

-KGDTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVWSL
 .  ...|..|||.. |.| || ..|.... |||||  |.|.  ||.. . ||| .|  .    .| |  |||||||||||     .  .||   |.|||
IQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVI-----RRKQYDEKVDIWSL

GITAIEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
|| ||||..| ||   |.| ||.| | .|  |....|.|||  ...| .||| .| .||... .|  |. .
GIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase AqueK234.AA KHS 53-319 41 1.3e-81 274.25 In-house 1-258 (258) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-258/258
Sequence Identity: 41% (113 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKEED---IQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGGSVTDLVKKIKD
.||. ..| | || |.| |. ..... |||..   .| ..|   || || .. |  .| |||  .| ||.|     ..|||.||.| |||. |    |  
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIK--MEPGDDFAVIQQEIMMM-KDCRHPNIVAYFGSYLRR-----DKLWICMEYCGGGSLQD----IYH

KGDTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYGRRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVWSLG
    |||  |||. .|.| || |||..  ||||||| |.|.| .| ..| |||..| .. . ..|.  ||||||||||| | |..    |.   |.|..|
VTGPLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK--GGYNQLCDIWAVG

ITAIEMVDGVPPLFGENPIRALYKIPKNP--PPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
|||||. .  ||.|   |.|||. . |    ||||.. .|||    .|.  .|.|.  .|||. .|  |...
ITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase AqueK234.AA PAKL 53-319 39 2.6e-81 276.42 In-house 1-256 (256) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-256/256
Sequence Identity: 39% (108 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEK-E-EDIQAEINVFQKYSSHENIVDCYGLYLKRQENSTE--QLWIVMEHCAGGSVTDLVKKIK
 |. || | | || |.|.  . |.   |.| .  . |  | .||. ||..  |  .  |||  .|        ...  ..|| |..|. ||. |. . . 
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIE-IKESNEIKDIEKEIQILKKCKC-PNIVSYFGSI------QQKLNHYWILMDYCSLGSINDMMESC-

DKGDTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHAYG-RRRTAIGTPYWMAPEVIACEHQLDYDYDVRADVWS
  ..|| |  |. ||  .| ||.|||  || |||||  |.|.. |. . . |||.      .|.      ||||||||||.|     .  .|.  .|.||
--CKTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEII-----NKQNYNNKCDIWS

LGITAIEMVDGVPPLFGENPIRALYKIPKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
|||||||| || ||. . .| ||.| ||  |||.. || .||  .| |.|.|.||| | |.   .|  |  |
LGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase AqueK234.AA Pkinase 53-319 28 2.4e-79 274.73 Pfam 1-293 (293) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKEEDIQA-----EINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGG----SVTDL
.....|||.|..|.|.|.....|||| ||||.. . ||..  |.     || . ..  .|.||| .|. .          ...|||.| ||    .  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDY

VKKIKDKGDTL--SEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRI----RLIDFGIAAAV-SHAYGRRRTAIGTPYWMAPEVIACEHQLD
..   ... ..  ||. .  .. ..| || |.|...|.|||.| .|.|.  .| |    ...|||.|. .    ..   |  |||..||||||      .
IST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GG

YDYDVRADVWSLGITAIEMVDGVPPLFGE----NPIRALYKIPKNPPPKLQNPTKWS---------------------IYLNQFIAKCLVKDFERRPTSG
 .|. ..|.||.|.. .||. | ||  |.    | .. ...| .. .|.|  .  |.                       . .|| .|| || ..|||  
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

QLTMHELI
|.  |. .
QILQHPWF
Kinase AqueK234.AA Pkinase_Tyr 53-309 26 1.3e-26 90.73 Pfam 1-262 (270) Show / Hide 
Range on Protein: 53-309
Range on HMM: 1-262/270
Sequence Identity: 26% (73 aa)

WELVEKIGKGNYGVVFKGRNR----KTGKIGAVKIM--DAVLEK--EEDIQAEINVFQKYSSHENIVDCYGLYLKRQENSTEQLWIVMEHCAGGSVTDLV
 .. .|.|.|..|.|.||. .    .|.   |||..  .|  |    ||  .|...  .. .|.||| .||  ....| .  |..||||....|   || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHG---DLL

KKIKDK---GDTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAV-SHAYG-RRRTAIGTPY-WMAPEVIACEHQLDYD
.  ...   .. |.   .  . ... .|. ||...|. |||.   |.| | .. ..  ||| | .. .  |  | |.    |  |||||.|.        
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-----

YDVRADVWSLGITAIEMVD-GVPP-LFGENPIRALYKI-PKNPPPKLQNPTKWSIYLNQFIAKCLVKDFERRPT
. .  |||| |..  |..  |  |   |  . . . .|  ..    .  | . .  . . . .|  .| |.|||
FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPT
Kinase AqueK234.AA TyrKc 53-319 24 1.6e-18 68.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-280/280
Sequence Identity: 24% (74 aa)

WELVEKIGKGNYGVVFKGRNRKTGKIGAVKIMDAVLEKEEDIQAEINVFQKY-SSHENIVDCYGLYLKRQENST---EQLWIVMEHCAGGSVTDLVKKIK
 .| .|.| |..|.|.||. .      ||| . .    .||.  |...  |.  .|.||| .||  .. ..|     |.|.||||....|.  |  .| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLRKHR

DKGDTLSEDIIAYILHEVLAGLVYLHNNNIMHRDIKGQNVLMTYDGRIRLIDFGIAAAVSHA--------YGRRRTAIGTP-----YWMAPEVIACEHQL
.|   |. .   .. . . .|  ||| .|. |||.   |.| . .....  ||| . .. .         | | ..  |.       |||||.|      
PK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----N

DYDYDVRADVWSLGITAIEMV-DGVPPLFG-----ENPIRALYKIPKN---PPPKL-----QNPTKWSIYLNQFIAKCLVKDFERRPTSGQLTMHELI
.. .    |||| |..  |.  .| .|  |      ...... .. .    |.|.        ..  .   .  . .|   | | |||  ..  ||..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
MYSc AqueK234.AA MYSc 373-1098 34 1.3e-284 952.69 SMART 1-771 (771) Show / Hide 
Range on Protein: 373-1098
Range on HMM: 1-771/771
Sequence Identity: 34% (285 aa)

LGLRTVELVSDLATLEYIDEEVIVGQLMKRYCKDLIYTYVGDVLVSINPFQNLPDIYNPKISAQYQ------GVTRASKSQMSPHIYAVAGAAYEEMIRE
   .  | |.|...|.|. |. ..  | ||| .|.|||| |.|....||...|| ||.| . .||.      |  |   . | |||.|.| .||  | ..
MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHR---YEMPPHIFAIADNAYRNMLND

SKDQCCVISGESGAGKTEASNILVQQLTQIGKAKTRSLGDKIVSLNPLLESFGNAKTVINNNSSRFGKYLEINFSRTGQVIGARLSEYLLEKSRVISQAG
...||..|||||||||||..  . | |. ..  ..... ..|.  ||.||.||||||| |||||||||| ||.|...| ..||  . ||||||||..|. 
KENQCIIISGESGAGKTENTKKIMQYLAAVSG-QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNK

KERNFHIFYYLIAGMRERKLSKRYKLKH----GQQFRYLHQIG-----------TGKATGKQNQGFVEKFNE----VEAAFELFGFSKKDFEQVCCILSG
 |||.||||.| ||     . ....||.     ....|| | |           . .  |      .| | |    .. |..  |||... |... |...
GERNYHIFYQLCAGAS-EEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVDGIDD---AEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAA

ILNIGDIHIEEDTKSPFHLEEVSC---ITNKQTLNDVCELLGISPAILEKVITHSSVMAHGE---TILRPNTVETAMDFRDAMAKSLYGRLFSWLVNRIN
|| .| | .|.. ..    .  .|   . ... |. .|||||..|. ||| .|| .. ...|   .| .|..|| |.. |||.|| .|.|||.|.|.|||
ILHLGNIEFEQGRNQ--YDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRIN

PTLCPSNDKNLSIGILDIFGFENFRVNSFEQLCINITNEQLQFYFNQHVFAWEQEEYDREGIDGTHIAYT--DNRPLLDLLLNR---PMGLLALLDEECK
 ..     .|..||.|||.|||.| .|||||.||| .||.|| .||.|.|  ||||| ||||. |.| ..  || | .||. ..   |||...||||||.
QSM-----HNYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECM

F---PRATDLSLALKL-----HQNLKHSPHYIKP-----------KDNGPTFMIEHYAGTVLYTTQGFLEKNRDTLKPEVASMLKESTNSIVQQLFTSTL
|   |..|| ... ||     ||..| .||. ||           ..  . | | ||||.| | . |.||||.||| ... . ...|.|....||| .. 
FHAQPKGTDQTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYE

SKT-------------------------GNLPDSSLSKIPFSATPLFNRRRPTHFQPSGGSHTPLSSISVATKHSQTVGTYFFYSLRELMAKMLQGTPHF
..|                         .                                 |    .   .|. .|||. |  .| |||... . .||.
DQTSQTPQEKSSQGKNKSRRKKRMMQMKK---------------------------------T----C-MQKKRFPTVGFQFK-QLNELMETLNSCHPHY

VRCIRPNDLKAPREFQPERVVEQLRHTGILETTRIRREGYSHRIFFEDFLQRYRIISY-KLSQYVT-------PTPINCVQVLMQ----------AGLEK
.|||.||. | |. | ...|  |||  |.||. ||||.|...|. ...|.|||....  ... . .         | . .....|             ..
IRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRWPYQEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDM

WAIGKTKVFLK-YYHIERLSHLLSN
...||||||.. ......| ..  .
YQFGKTKVFFRNPGQLFHLEEMRER
Myosin_head AqueK234.AA Myosin_head 381-1085 33 1.8e-241 813.29 Pfam 1-765 (765) Show / Hide 
Range on Protein: 381-1085
Range on HMM: 1-765/765
Sequence Identity: 33% (273 aa)

VSDLATLEYIDEEVIVGQLMKRYC-KDLIYTYVGDVLVSINPFQNLPDIYNPKISAQYQGVTRASKSQMSPHIYAVAGAAYEEMIRESKDQCCVISGESG
| |.. |.|. |. .   | |||  .||||||.|....|.||...|| || ... . | |     .. | |||.|.| .||. | .. ..||..|.||||
VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLP-IYTQDMIQEYRGKH---RYEMPPHIFAIADEAYRHMRHDRENQCIIICGESG

AGKTEASNILVQQLTQIGKAKT----RSLGDKIVSLNPLLESFGNAKTVINNNSSRFGKYLEINFSRTGQV----IGARLSEYLLEKSRVISQAGKERNF
|||||.. .. | .. ..        ... ..|.  ||.||.||||||. ||||||||||.||.|  ||..    .|.. . ||||||||. |. .||||
AGKTENTKYVMQYFASVSGSNPGVNMGRVEQQILQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNF

HIFYYLIAGMRERKLSKRYKLK--HGQQFRYLHQIG---TGKA-TGKQNQGFVEKFNEVEAAFELFGFSKKDFEQVCCILSGILNIGDIH-IEEDTKSPF
||||.| ||  . .. | ..|.     ...|| | |   . ..  |  .   .| | ... |. . ||.... .... |...||..| .   ..|     
HIFYQLLAGASQQEEKKELHLTSADPKDYHYLNQSGTNPCYTVDDGIDD---AEEFQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQ----

HLEEVSCITNKQT-LNDVCELLGISPAILEKVITHSSVMA----HGETILRPNTVETAMDFRDAMAKSLYGRLFSWLVNRINPTLCPSN-----------
  || . . ...  ....|||.|..|. .|| ...  . .    . |.. .| ..| ||. |||.|| .|.|.| |.||||| ..|              
-NEEQAVVDDTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRINQAICHKTQNTDDSDGQAA

-------------------DKNLSIGILDIFGFENF-RVNSFEQLCINITNEQLQFYFNQHVFAWEQEEYDREGIDGTHIAY-TDNRPLLDLLLN-RPMG
                   ..|. ||.|||.||| |  .|||||.||| .||.|| .||.|.|  ||||| ||||. |.| | .|| |  ||. . .|||
QWDDTVSITVVDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCDLIEKKKPMG

LLALLDEECKFPRATDLSLALKLHQNL-KHSP--HY-IKP-K-----DNGPT-FMIEHYAGTVLYTTQGFLEKNRDTLKPEVASMLKESTN-SIVQQLFT
.|.||||||.||.||| ... ||.|.   ..|  |.  || .      .|.| | | ||||.| | ..|.||||.|.| ... . ...|.. ...|.|| 
ILSLLDEECWFPKATDQTFLQKLYQTHSSKHPRLHFAQKPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELFP

S-TL-----SKTGNLPDSSLSKIPFSATPLFNRRRPTHFQPSGGSHTP-------------------LSSISVATKHS-QTVGTYFFYSLRELMAKMLQG
. ..      .                                   ..                    .. .  .|.  |||.  |  .. .||. . | 
DWEWAEWAHMQ-----------------------------------IDFEADFHEEEFKRRYNRNGCQKGKQGKKKWFMQTVWFQFKEQCNHLMKWLYQC

---TPHFVRCIRPNDLKAPREFQPERVVEQLRHTGILE-TTRIRREGYSHRIFFEDFLQRYRIISYKL------SQYVTPTPINCVQVLMQA---GL--E
   .||.||||.||. |.|..| ...| .|||  |.|| . ||.|.|...|. . .|.||||| . |       .  .  |  .|  .| .    ..  |
AWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPKTWWSWIWPEWNGDTKQGCEKILQHLSWGNMDKE

KWAIGKTKVFLK
....||||.|..
EYQFGKTKIFFR
IQ AqueK234.AA IQ 1100-1120 47 1.8e-05 21.61 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1100-1120
Range on HMM: 1-21/21
Sequence Identity: 47% (10 aa)

HCLATRIQRVARGWLARKEAD
|  |..||.. ||.||||.  
HRAAIKIQAWWRGYLARKHYR
IQ AqueK234.AA IQ 1098-1120 43 0.01251 15.9 SMART 1-23 (23) Show / Hide 
Range on Protein: 1098-1120
Range on HMM: 1-23/23
Sequence Identity: 43% (10 aa)

NYHCLATRIQRVARGWLARKEAD
  |  |..||. .||.||||.  
RMHRAAIIIQAWWRGYLARKRYK
IQ AqueK234.AA IQ 1125-1145 38 2.1e-08 31.1 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1125-1145
Range on HMM: 1-21/21
Sequence Identity: 38% (8 aa)

EKAIVKLQSFIRGFLVRKSFK
..|..|.|...||.|.|| ..
HRAAIKIQAWWRGYLARKHYR
IQ AqueK234.AA IQ 1123-1145 39 1.2e-07 32.69 SMART 1-23 (23) Show / Hide 
Range on Protein: 1123-1145
Range on HMM: 1-23/23
Sequence Identity: 39% (9 aa)

RKEKAIVKLQSFIRGFLVRKSFK
|...|....|...||.|.|| .|
RMHRAAIIIQAWWRGYLARKRYK
IQ AqueK234.AA IQ 1152-1172 42 2.9e-08 30.64 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1152-1172
Range on HMM: 1-21/21
Sequence Identity: 42% (9 aa)

HKAVVLIQKGFRGHLCRHKYQ
|.|...||. .||.|.| .|.
HRAAIKIQAWWRGYLARKHYR
IQ AqueK234.AA IQ 1150-1172 39 3.6e-08 34.38 SMART 1-23 (23) Show / Hide 
Range on Protein: 1150-1172
Range on HMM: 1-23/23
Sequence Identity: 39% (9 aa)

QRHKAVVLIQKGFRGHLCRHKYQ
..|.|...||. .||.|.|..|.
RMHRAAIIIQAWWRGYLARKRYK
IQ AqueK234.AA IQ 1178-1198 33 8e-06 22.72 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1178-1198
Range on HMM: 1-21/21
Sequence Identity: 33% (7 aa)

RRAATIIQSSFRMWICKKQLL
.|||..||. .|.....|.. 
HRAAIKIQAWWRGYLARKHYR
IQ AqueK234.AA IQ 1176-1198 34 1.1e-05 26.19 SMART 1-23 (23) Show / Hide 
Range on Protein: 1176-1198
Range on HMM: 1-23/23
Sequence Identity: 34% (8 aa)

KERRAATIIQSSFRMWICKKQLL
...|||.|||. .|.. . |.  
RMHRAAIIIQAWWRGYLARKRYK
IQ AqueK234.AA IQ 1204-1224 38 0.001556 15.32 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1204-1224
Range on HMM: 1-21/21
Sequence Identity: 38% (8 aa)

IQKAIVIQRNVRKWLVYKHEK
 . ||.||. .| .|. || .
HRAAIKIQAWWRGYLARKHYR
IQ AqueK234.AA IQ 1202-1224 34 0.777339 1.05 SMART 1-23 (23) Show / Hide 
Range on Protein: 1202-1224
Range on HMM: 1-23/23
Sequence Identity: 34% (8 aa)

LEIQKAIVIQRNVRKWLVYKHEK
 . . ||.||. .| .|. |. |
RMHRAAIIIQAWWRGYLARKRYK