Gene AqueK249 (A.queenslandica)

AqueK249

Species: A.queenslandica
Alias: AqueK249
External Links:
Annotation:

Classification

Group: TK
Family: Abl

Sequence

Name Sequence Type Origin Length Description Download
AqueK249.AA Protein None 813 None Fasta, JSON
AqueK249.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of AqueK249.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK249.AA SH3 110-167 32 4e-15 57.48 SMART 1-58 (58) Show / Hide 
Range on Protein: 110-167
Range on HMM: 1-58/58
Sequence Identity: 32% (19 aa)

NLYVVKHDYVTNQSGQLSIRKGDKIRVTPGRGTGDWVEGTNA-NGQTGWLPASYIAKID
  .....||   ... ||..|||.|.|.     ..| .|..  .||.|| |..|...||
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 AqueK249.AA SH3_2 111-166 23 4.6e-11 41.64 Pfam 1-68 (68) Show / Hide 
Range on Protein: 111-166
Range on HMM: 1-68/68
Sequence Identity: 23% (16 aa)

LYVVKHDYVT-NQSGQ-----LSIRKGDKIRVT--PGRGTGDWVEG-TN-ANGQT--GWLPASYIAKI
.|.|  |||  .  .      |...|||.|.|.  ...  ..|... .. ..|..  || | ......
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH3_1 AqueK249.AA SH3_1 113-160 40 7.6e-11 39.65 Pfam 1-49 (49) Show / Hide 
Range on Protein: 113-160
Range on HMM: 1-49/49
Sequence Identity: 40% (20 aa)

VVKHDYVTNQSGQLSIRKGDKIRVTPGRGTG-DWVEGTNAN-GQTGWLPA
|...||. .|.. ||..|||.| |   .  . || .| . | ||.|| |.
VALYDYQAQQPDELSFKKGDIIHVI-EKSDDWDWWKGRCNNTGQEGWFPS
SH2 AqueK249.AA SH2 174-250 46 1.4e-40 121.01 Pfam 1-81 (81) Show / Hide 
Range on Protein: 174-250
Range on HMM: 1-81/81
Sequence Identity: 46% (38 aa)

WFFGNITRAEAELNLGS--GINGSFLIRESESKPGQYSISLRFEG---RVFHYRIHIDPSSEQYYVTPESKFDTLTELVKHH
|..|.|.|.|||  | .  . .|.||.|||||.||.|..|.|..|   || ||||. ..   .||.| . ||..| ||| |.
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG-GYYITGRHKFCSLQELVEHY
SH2 AqueK249.AA SH2 172-256 42 2.5e-33 117.96 SMART 1-87 (87) Show / Hide 
Range on Protein: 172-256
Range on HMM: 1-87/87
Sequence Identity: 42% (38 aa)

HSWFFGNITRAEAELNLGS--GINGSFLIRESESKPGQYSISLRFEGRVFHYRIHIDPSSEQYYVTP--ESKFDTLTELVKHHSKNADG
. |..|||.|.|||  | .  . .|.||.|.|||.||.|..|.|..|.| ||||. ...  .||..   . ||..| ||| |...|..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK249.AA Abl 290-541 67 4.4e-162 544.77 In-house 1-252 (252) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-252/252
Sequence Identity: 67% (171 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLRSTEGKTLDAVVLV
. |  |||||||||||..| |  .  ||||| .|.| .  |||||| .||..||||||||||||||| ||.||||.|..||||||||... ..|.||||.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

YMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLMESDIYNAREGAKFPIKWTAPEALAYNKFSIKSDVWAFGVLLWELATYGMSPYP
||| |.||.| |||. . ||||||||||||||. .||||||||.|.|. |.| |. ||||||||||||.|||||||.|||||||||||||.|||||||||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYP

GAELAQVYELLESGYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRIL
| .| .||..|| ||||. |||||  ||.|| |||.| . |||||.|. . .
GIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK249.AA Pkinase_Tyr 290-541 49 1.9e-147 499.99 Pfam 1-270 (270) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-270/270
Sequence Identity: 49% (133 aa)

LEMGLKLGGGQYGEVYKAVMK----GRGVNVAVKTFREETTDA----TEFLKEANVMKKV-KHPNLVQLLGVCT-RELP--FFIITEYMPKGNLLDYLRS
...| ||| |..|||||...|    . .. ||||. .| ...      .|..||..||.  .|||.|.|.|||| .. |   .|..||||.|.||||||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

T--EGKTLDAVVLVYMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLM-ESDIY-NAREGAKFPIKWTAPEALAYNKFSIKSDVWAF
   ... |.   |. |..|.|..|.|||..|.||||||||||||.||  ||..||||.|.. . | |  .|.|.|.||||.|||...|.||..|||||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVLLWELATYGMSP-YPGAELAQVYELL-ESGYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRIL
|||.||. |||..| |||   ..|||.. |.||||  ||.||  .|.||.|||.. |||||.|.|. ..|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK249.AA SFK-Abl 292-541 54 1e-145 478.74 In-house 3-251 (251) Show / Hide 
Range on Protein: 292-541
Range on HMM: 3-251/251
Sequence Identity: 54% (137 aa)

MGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLRSTEGKT-LDAVVLVY
.|  ||.|||||||| .   .   ||.|| ..|   . .|.||| .||. .|||||.|.||||||.| .|..|.|. |||||||.|  .   .| | . .
LGHRLGEGQYGEVYKGIWNNH--RVAIKTIKDESMETKDFMKEAHIMKRMQHPNLVRLIGVCTREGPMYIVQEFMNYGNLLDYLQSPQSRIQIDHVSMMH

MAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLMESDIYNAREGAKFPIKWTAPEALAYNKFSIKSDVWAFGVLLWELATYGMSPYPG
 |||.|  |  ||  . |||||||||||||.|  .||||||. |. .||.| || | |.||||||||.|.|  |.||||||.||. ||| ||||  ||||
CAQQIADGMSFLEEQHFIHRDLAARNCLVGDNLQIKVADFGMARFVDSDFYEARIGTKMPIKWTAPESLCYDIFTIKSDVWSFGITLWEIATYGDVPYPG

AELAQVYELLESGYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRIL
 .  .| . |. ||||| |..||  .|| |||||.  |. |||| .| . |
IHHRDVINQLMMGYRMQRPQDCPMEIYNIMTQCWDVNPDERPSFHDLQHQL
Kinase AqueK249.AA TyrKc 290-541 44 4.2e-142 479.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-280/280
Sequence Identity: 44% (126 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKV--KHPNLVQLLGVCTRE-------LPFFIITEYMPKGNLLDYLRSTEG
...| ||| |..|||||...|   ..||||. .|..    .|..||..|.|.  .|||.|.|.|||| .        | .|..||||.|.|.||||....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KTLDAVVLVYMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLMESD--------IYNARE--GAK--FPIKWTAPEALAYNKFSIKS
| |    |.... |.|. |.||. .| |||||||||||||||. ||..||||||  ..|         | ..|  |.|  .||.|.|||.. |.||..||
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVWAFGVLLWELATYGMSPYPG-----AELAQVYELLESGYRMQNPEG--------CPSAVYNLMTQCWEWLPEDRPSFAELSRIL
|||.|||..||. |||..||||      . ..|.|....||||  |.         ||...|..|.|||.  |||||.|.|. ...
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK249.AA Src 290-541 54 4.6e-142 478.26 In-house 1-255 (255) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-255/255
Sequence Identity: 54% (139 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLR-STEGKTLDAVVL
. .  ||| ||.|||.... .|. ..||||| .. | . . ||.||..|||..|..||||. ||..| |..|.|||| .|.|||||. ..||..|    |
IKLCRKLGQGQFGEVWMGYWNGN-TKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQL

VYMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLME--SDIYNAREGAKFPIKWTAPEALAYNKFSIKSDVWAFGVLLWELATYGMS
..|| |||. ||||| ||.||||||||| ||||| ..||||||| ||..   |.|.||.|||||||||||||. |..|.|||||| ||.||.|. |||  
IDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPGAELAQVYELLESGYRMQNPEGCPSAVYN-LMTQCWEWLPEDRPSFAELSRIL
|||| . ..| . .| |||| .|..||  .|. .|.|||.  ||.|| |. |   |
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK249.AA SFK-Src 290-545 51 2.1e-139 416.09 In-house 1-259 (259) Show / Hide 
Range on Protein: 290-545
Range on HMM: 1-259/259
Sequence Identity: 51% (133 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLRSTEGKTLDAVVLV
 ..  ||| ||.|.|.| .  .   .||||| .  .. | |||.|| |||| .||||.||  |||   | .|||| |  | |||||.. .|. |    ||
IRLEKKLGSGQFGDVWKGRWNNT-TEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLV

YMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLMESD-I-YNAREGAKFPIKWTAPEALAYNKFSIKSDVWAFGVLLWELATYGMSP
 || |||. |||||  | .|||||||| |||.|  .||.|||.|| .. | . | |.||||||||||||||  .|.||||||||.||.|. |. |||  |
DMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIP

YPGAELAQVYELLES--GYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRILNGLS
|||   . |   ..   ||||  | .|| . |..| .||   |.||| |  |   .    
YPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK249.AA TK 290-541 26 7.2e-124 417.4 In-house 1-486 (486) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-486/486
Sequence Identity: 26% (131 aa)

LEMGLKLGGGQYG---EVYKAVMKGRG-------------------------VNVAVKTFREE-TTDATE--------------FLKEANVMKKVK----
...| ||| ||.|   ||||. ..||.                         . ||||. .|. .....|              ||.||..||. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQLLGVCTRE------------LPFFIITEYMPKGN----LLDYLRSTEGK--------------------------------------------
 |||.|.|.||||..             |. |..||||.|.    |.||||.  .|                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------TLDAVVLVYMAQQVASAMAYLENM------NMIHRDLAARNCLVGENYL-----------VKVADFG---
                              .|.   |. |..|.|..|.||. .      |..||||||||||||||.            .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRLMESD-IYNARE------------------------GAKFPIKWTAPEALA---------YNKFSIKSDVWAFGVLLWELATYG-MSPYP--
     |.| ..||  | ...                        |.|.||.|.|||.|.         |.||..|||||.||||.||. ||| . .|.  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------GAELAQVYELLESG--------------YRMQNPEGCP--------------SAVYNLMTQCWEWLPEDRPSFAELSRIL
        | ....|.|.|..|              .||  |..||               ..| ||.|||.. |||||.|..| . |
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK249.AA Src-Unclassified 290-541 44 2.9e-122 412.5 In-house 1-284 (284) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-284/284
Sequence Identity: 44% (127 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREE---TTDATEFL--------KEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLRST
.    ||| || |||...  .|  | ||||| |.    |   . ||        .||..||| .|.|||.|..||..| |..|||||| .| ||..||  
VHLLRKLGRGQFGEVWYGKWRGK-VDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREG

EGKTLDAVVL------------VYMAQQVASAMAYLENMNMIHRDLAARNCLVGENY-----LVKVADFGLS--RLMESDIYNAREGAKFPIKWTAPEAL
 |..|    .            |..| |||| | |||   ..|||||||| |.|.|      .|||.||||   .||. |.| .| ||.||.||.|||. 
GGQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECF

AYNKFSIKSDVWAFGVLLWELATYGMSPYPGAELAQVYELLESGYRMQNP--EGCPSAVYN-LMTQCWEWLPEDRPSFAELSRIL
 | .|||||||| .|.||||..|.|  ||||     | | .|.||||  |  ..||  .|  .|..||   |. || |  |   .
IYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK249.AA SrcB 290-542 52 9.1e-108 364.33 In-house 1-251 (251) Show / Hide 
Range on Protein: 290-542
Range on HMM: 1-251/251
Sequence Identity: 52% (132 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLRSTEGKTLDAVVLV
| .  ||| ||.|||. .  ..  . |||||... |     ||.||||||...|  ||.|  | |.| | .|||||| || |||.|.. ||  |    |.
LKLVKKLGAGQFGEVWMGYYNNH-MKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLI

YMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLMESDIYNAREGAKFPIKWTAPEALAYNKFSIKSDVWAFGVLLWELATYGMSPYP
 |. |.|  |||.|.|| ||||| | | || |  . |.||||| |..|.. | ||||||||||||||||. .  | ||||||.||.|| |. |||  |||
DMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GAELAQVYELLESGYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRILN
|   ..| . || ||||  |. ||  .||.|..||   ||.|| |  |  .|.
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK249.AA Frk 290-545 50 1.3e-107 363.77 In-house 1-260 (260) Show / Hide 
Range on Protein: 290-545
Range on HMM: 1-260/260
Sequence Identity: 50% (131 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLR--STEGKTLDAVV
...  .|| ||.|||.        . ||||| .  | | ..||.|| .|||..|| |.||  |||.| | .|||| | .| |..||.  . .|. .    
IQLIRRLGSGQFGEVWEGLWN-NTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQ

LVYMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSR-LMESDI--YNAREGAKFPIKWTAPEALAYNKFSIKSDVWAFGVLLWELATYG
|| || |||. |||||..| ||||||||| ||||.  .|.||||| | ||  ..  | .| ||.||||||||||  ||||.||||||.||.|| |. |||
LVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYG

MSPYPGAELAQVYELLESGYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRILNGLS
  ||||   |.| . .. |||| .| .||  .|..| .||.  |. || |  |   |.   
RMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK249.AA Tec 290-543 43 2.2e-106 359.7 In-house 1-254 (254) Show / Hide 
Range on Protein: 290-543
Range on HMM: 1-254/254
Sequence Identity: 43% (111 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKGNLLDYLRSTEGKTLDAV-VL
| .   || ||.| |  .  ..    ||.|. .| .    .|. || ||.|  ||.|||| |||. . | .|.|||| .| ||.|||. ...   .. .|
LTFMKELGSGQFGVVHLGKWRH-QYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAIL

VYMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLMESDIYNAREGAKFPIKWTAPEALAYNKFSIKSDVWAFGVLLWELATYGMSPY
 .| |.|  .|||||  . |||||||||||||..  |||.|||..|    | |    |.|||.|| .|| . |...| |||||||||| ||  . |  ||
LEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPY

PGAELAQVYELLESGYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRILNG
.  .  .| |    |.|.  |. |.  .|  | .||.  ||.||.|..| | .  
ENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK249.AA UTK 290-541 37 2.7e-104 352.78 In-house 1-296 (296) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-296/296
Sequence Identity: 37% (112 aa)

LEMGLKLGGGQYGEVYKAVMKGRG-----VNVAVKTFREETTDATE------FLKEAN---VMKKVK-HPNLVQLLGVCTRELPFFIITEYMPKGNLLDY
.. | .|| |..|||.||  .        . ||||. ... .. .|      |..||.   .||... |||...|.||||.| |. |.||||..|.|..|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRSTEGKT------LDAVVLVYMAQQVASAMAYLENMNMIHRDLAARNCLVGEN-------YLVKVADFG---LSRLME----------SDIYNAREGAK
||.   ..      |.   ...|| ..|..|.||.... .|||||||||||...       ...|.||||   .||..           |. |.|..  .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPIKWTAPEALAYN-KFSIKSDVWAFGVLLWELATYGMSPYPGAELAQVYELLESG--YRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSRIL
 ||.|.|||||... .|..|||||.|||..||. |.|  ||||   .|| . .. |  |||  |..|| .||.||..||.  |..||.| .|   .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK249.AA S_TKc 290-540 23 5.4e-59 203.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 290-540
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATEFLKEANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPK--GNLLDYLRSTEG----KTL
 |.. |.| | .|.|||.. |. |  ||.|  .        ...| ...|| .|||.|.|..|.     .....||..   |.|.||...  .    . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DAVVLVYMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLVKVADFGLSRLMESDIYNAREGAKFPIKWTAPEALAYNKFSI-KSDVWAFGVLLWELAT
.  .  ....|...|..|. ... |||||   | |. |   .|..||||.|..                . ||| |   ...  |.|.|..|..|.|...
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

YGMSPYPGAELAQVYELLESGYRMQNPEGCPSAVYNLMTQCWEWLPEDRPSFAELSR----------I
 |  |.|  .........            .. . ... .|... ||.||.  |. .          .
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK249.AA Pkinase 290-541 21 8.2e-47 166.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 290-541
Range on HMM: 1-293/293
Sequence Identity: 21% (64 aa)

LEMGLKLGGGQYGEVYKAVMKGRGVNVAVKTFREETTDATE---FLK--EANVMKKVKHPNLVQLLGVCTRELPFFIITEYMPKG----NLLDYLRSTEG
.. | |.| | .|.|||.. || |  ||||... ....  .    ..  |. .||...||| |.|.......    ...||...|     | ||..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KTL--DAVVLVYMAQQVASAMAYLENMNMIHRDLAARNCLVGENYLV----KVADFGLSRLMESDIYNAREGAKFP---IKWTAPEALA-YNKFSIKSDV
...  .  ..  .. |......|. .|. |||||   |.|. .|. .    |..||||.....   |   . .. .   . . ||| .  ... . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WAFGVLLWELATYGMSPYPGA----ELAQVYELLESGYRMQNPEGCP-----------------------SAVYNLMTQCWEWLPEDRPSFAELSRI--L
|..|..|.|... |  |.||.    . .  .....   . .... .|                       ..   ... |... |..||.....     .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF