Gene AqueK257 (A.queenslandica)

AqueK257

Species: A.queenslandica
Alias: AqueK257
External Links:
Annotation:

Classification

Group: TK
Family: DDR

Sequence

Name Sequence Type Origin Length Description Download
AqueK257.AA Protein None 740 None Fasta, JSON
AqueK257.kin_dom Protein Kinase Domain None 270 None Fasta, JSON

Protein domain

Protein domains of AqueK257.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IG AqueK257.AA IG 182-266 12 1.3e-05 25.87 SMART 1-58 (58) Show / Hide 
Range on Protein: 182-266
Range on HMM: 1-58/58
Sequence Identity: 12% (11 aa)

VTLGPDNIQSSISINCTVLNNGSFHWNWLFNNTIPITDELFVEDATRTSILNINGLSYSNE---GNYTCTANSTAGSTAS-KIIQIRIS
      .  ......| |    ...|                        |.| .......   |.|.|.|.  .|.. | . ......
PP-VTVKEGETVTLTC-VS---QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
IGc2 AqueK257.AA IGc2 188-254 19 0.000117 19.54 SMART 1-56 (56) Show / Hide 
Range on Protein: 188-254
Range on HMM: 1-56/56
Sequence Identity: 19% (13 aa)

NIQSSISINCTVLNNGSFHWNWLFNNTIPITDELFVEDATRTSILNINGLSYSNEGNYTCTANSTAG
..  |....| . .|      |...  .|             . |.|   ... .|.|||.| . .|
HEGQSVTLTCPATGNPDPNIHWYKGQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG
TyrKc AqueK257.AA TyrKc 443-723 33 1e-98 335.21 SMART 1-280 (280) Show / Hide 
Range on Protein: 443-723
Range on HMM: 1-280/280
Sequence Identity: 33% (107 aa)

FEEIALLGTGQFGEVVLAKTIGLSLKDLRLDKTDDDKFATVRVAVKKIRENQSDESIIALKKEIKFMSQL--DHNNVVRLLAVSAESC------QEQFIV
 . .  || |.||||.... .                   . ||||...|.     . .. .|.. |..|  .| |.|||..|  ..       .  .||
ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

MEYMENGDLNKFLMDHSFTDSHPPEENELSPNILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDS-------SYYKVSG-
||||..|||...| .|  .         |..  |||||.|.|.||.||.|.|.|||||| ||.||| ...||..||||||..||        .||.... 
MEYMPHGDLKDYLRKHRPK---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH

-KAK--MPIRWMAKECF-YGKFSEVTDLWAFGVTVWEIYMMSRDYPYS----FMTDQEVIDNALKGFNCVLLEKPET--------CPERVFSVIVKLCWS
  .|  .|||||| ||. ||||.. .| |.|||. |||.      ..     .|..|||| .  .|.    ...|.         ||. ... | | || 
KGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY---RMPQPPNDYPMSFVCCPDEMYQ-IMKQCWH

K---ERKTFAQVHKEL
    .| ||...|...
EDPEDRPTFSEIHECF
Pkinase_Tyr AqueK257.AA Pkinase_Tyr 443-723 36 2e-92 313.65 Pfam 1-270 (270) Show / Hide 
Range on Protein: 443-723
Range on HMM: 1-270/270
Sequence Identity: 36% (108 aa)

FEEIALLGTGQFGEVVLAKTIGLSLKDLRLDKTDDDKFATVRVAVKKIRENQSDES--IIALKKEIKFMSQL-DHNNVVRLLAVSA-ESCQ-EQFIVMEY
 . .  || |.||||....  |            |..  .. ||||...|. ..|   . .. .|.| |.|| .| |.|||..|   .. . . .|||||
ITFGKKLGEGAFGEVYKGTWKG------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY

MENGDLNKFLMDHSFTDSHPPEENELSPNILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDSSYY-KVSGKAKMPIRWMA
|..||| ..| .|.      .... |..  ||..|.|.|.||.||.|.|.|||||| ||.||. . .||..||||.| .|. .|| ...|..|.||.|||
MPHGDLLDYLRKHR------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMA

KEC-FYGKFSEVTDLWAFGVTVWEIYMMSRDYP-YSFMTDQEVIDNA-LKGFNCVLLEKPETCPERVFSVIVKLCW---SKERKTFAQVHKEL
 || .||||.. .| |.|||. |||.   .  | |  |...||..    .|     ...|| ||. . ..  |.||    ..| ||...| .|
PECINYGKFTTKSDVWSFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYR---MPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK257.AA DDR 446-723 38 1.6e-86 293.75 In-house 4-306 (306) Show / Hide 
Range on Protein: 446-723
Range on HMM: 4-306/306
Sequence Identity: 38% (120 aa)

IALLGTGQFGEVVLAKTIGLS---LKDLRLDKTDDDKFATVRVAVKKIRENQSDESIIALKKEIKFMSQLD-HNNVVRLLA--VSAESCQEQFIVMEYME
  ..| |||||| |  . |.     .|  .|.    |   . ||||. |.  ..    .. |||| |||.  | |.|||..  .  |.     ..|||||
VEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDV---HKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPY---CMIMEYME

N-GDLNKFLMDHSFTDSHPPEEN---------ELSPNILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFG--LSRNLYDSSYYKVSG-
| |||| |.| |   .|   . .          .|   ... | |.| || ||.| ||.||||| ||.|||..| .|. |||  .||||| . ||.| | 
NLGDLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGF

----KAKMPIRWMAKEC-FYGKFSEVTDLWAFGVTVWEIYMMSRDYPYSFMTDQEVIDNA----LKGFNCVLLEKPETCPERVFSVIVKLCWSKERK---
    .. ||||||| |.   |||.  .| ||||||.||. |. |  ||. .||  ||.||     .. . |.| .|  ||. ..    . ||. . .   
TGRQRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRP

TFAQVHKEL
.|...|| |
SFEEIHKFL
Kinase AqueK257.AA TK 443-723 21 4.2e-84 281.73 In-house 1-486 (486) Show / Hide 
Range on Protein: 443-723
Range on HMM: 1-486/486
Sequence Identity: 21% (103 aa)

FEEIALLGTGQFG---EVVLAKTIGLSLK-----------DLRLDKTDDDKFATVRVAVKKIRENQSDESIIA--------------LKKEIKFMSQ--L
 . .  || ||||   || ... .|.. .           .|.. .  ...  .| |...|   ..|.|  ..              .  |.| |..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHNNVVRLLAVSAESC-----------QEQFIVMEYMENGD----LNKFLMDH---------SFTDSHPPEENE--------------------------
.| |.|||..|. ..            .   ||||||..||    | ..| ..         .  ..|......                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSPNILLSFCIQVANGMSYLSSR------NFIHRDLASRNILVGPDYI-----------VKVGDFG---
                               |..  || .| |.|.||.||.|.      ||.||||| ||.||| ...           .|..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRNLYDSSYYKVSG------------------------KAKMPIRWMAKECFY----------GKFSEVTDLWAFGVTVWEIYMMSRDYPYSFM
     |.| .|....| ...                        ..|.|||||| ||.           |||.. .| |.|||..|||..  .  .|  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------QEVIDNALKGFNC-----------VLLEKPETCPE-------------RVFSVIVKLCWSKE---RKTFAQVHKEL
..         |||...  .|                ...|. ||.              ..  . . ||...   | ||.|.|..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK257.AA TK-Unique 443-723 28 2.6e-73 249.85 In-house 1-294 (294) Show / Hide 
Range on Protein: 443-723
Range on HMM: 1-294/294
Sequence Identity: 28% (89 aa)

FEEIALLGTGQFGEVVLAKTIGLSLKDLRLDKTDDDKFATVRVAVKKIRENQSDESIIALKKEIKFMSQLD-HNNVVRLLAVSAESCQEQFIVMEYMENG
.|   ..|.|.||.|  ..  |..           . .....||||. ..| .|..  ...|||..|..|. | |.|..| .. .| . ..|.|||...|
LEVGDVIGEGAFGQVWRGEVWGIW----------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCG

DLNKFLM-------DHS------FTDSHPPEENE---LSPNILLSFCIQVANGMSYLSS--RNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDSSYYK
.| ..|        .|       |.  |.|....   .||  |..|..|.|.||.||.|  ....||||..||.|.. |...|..|||..| .|.   | 
NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYS

VSGK-AKMPIRWMAKECFY---GKF-SEVTDLWAFGVTVWEIYMMSRDYPYSFMTDQEVIDNALKGFNCVLLEKPETC-PERVFSVIVKLCWSKERK---
 ...  ..||||||.| ..   | . .. .| |.|||. |||  .   .||. | . .....  .|..   ...|| | ........   ||..|..   
MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKDIMECIRDGYR---MPQPEHCCSHEMYNLMKS-CWQWEPEERP

TFAQVHKEL
.|.|. ..|
SFRQIKHRL
Kinase AqueK257.AA UTK 443-723 28 2e-63 215.85 In-house 1-296 (296) Show / Hide 
Range on Protein: 443-723
Range on HMM: 1-296/296
Sequence Identity: 28% (90 aa)

FEEIALLGTGQFGEVVLAKTIGLS---LKDLRLDKTDDDKFATVRVAVKKIRENQSDESI-IA-LKKEIK---FMSQLD-HNNVVRLLAVSAESCQEQFI
 .  ..|| |.|||| .|.    |   .....  |. .             ...  .|.   . . .| .   .|.|.. | ||.||..|   . .   |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ------------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMI

VMEYMENGDLNKFLMDHSFTDSHPPEENELSPNILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPD-------YIVKVGDFG---LSRNLY------
|.|||||||| ..|..|.  .. |...  |.   .|... ..|.||.||.|..|.||||| ||.||. .       ...|..|||   .||...      
VTEYMENGDLRSYLRRHR--PTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSN

---DSSYYKVSGKAKMPIRWMAKECFYGK--FSEVTDLWAFGVTVWEIYMMSRDYPYSFMTDQEVIDNALKG-FNCVLLEKPETCPERVFSVIVKLCWSK
   .| ||. ..  ..|||||| |...    |.. .| |.|||..|||...    ||  |....|. . ..|     ....|. ||..|.  ... || .
RYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW-GRLPYPGMSNMQVWHQVCNGGR--YRMPCPWDCPHPVYR-LMHRCWHY

---ERKTFAQVHKEL
   || .| .. ...
DPQERPDFEDLVQQM
Kinase AqueK257.AA Src 482-723 35 3.4e-60 203.21 In-house 23-255 (255) Show / Hide 
Range on Protein: 482-723
Range on HMM: 23-255/255
Sequence Identity: 35% (90 aa)

TVRVAVKKIRENQSDESIIALKKEIKFMSQLDHNNVVRLLAVSAESCQEQ---FIVMEYMENGDLNKFLMDHSFTDSHPPEENELSPNILLSFCIQVANG
.. |||| ... .   |  |. .|.. | .|.|...|.|.||    | .    .|| |||..| | ..| .        .|. .|. ..|...  |||.|
NTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAV----CSQEEPIYIVTEYMSHGSLLDYLKK-------DGEGRHLHLPQLIDMAAQVAEG

MSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYD--SSYYKVSGKAKMPIRWMAKECF-YGKFSEVTDLWAFGVTVWEIYMMSRDYPYSFMTDQ
|.||.|.|.|||||| ||.||| . ..||.|||| | | .     |  .  ||.||.|.| |.. ||.|.  .| | ||.  .||    | .||  || .
MAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGR-VPYPGMTNH

EVIDNALKGFNCVLLEKPETCPERVFSVIVKLCWSK---ERKTFAQVHKEL
||...  .|.    . .|..||....  | . || |   .| ||.  .. |
EVLQQVERGYR---MPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK257.AA Trk 446-723 32 6.3e-60 201.81 In-house 4-275 (275) Show / Hide 
Range on Protein: 446-723
Range on HMM: 4-275/275
Sequence Identity: 32% (95 aa)

IALLGTGQFGEVVLAKTIGLSLKDLRLDKTDDDKFATVRVAVKKIRENQSDESIIALKKEIKFMSQLDHNNVVRLLAVSAESCQEQFIVMEYMENGDLNK
.  || | || |.||.   |.         ..||     |||| ...    .     ..| . . .|.|...|..  |  .  .  ..| |||..|||||
KWELGEGAFGKVFLAECYNLC--------PEQDKMM---VAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDH-DPLLMVFEYMKHGDLNK

FLMDHS-----FTDSHP-PEENELSPNILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYD-SSYYKVSGKAKMPIRWMAKE
.|  |      ...  |     .|  . .|    |.| || |. |  |.|||.| || ||| . |||.||||.|| .|. . ||.| ..  .|||||  |
YLRQHGPDAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPE

C-FYGKFSEVTDLWAFGVTVWEIYMMSRDYPYSFMTDQEVIDNALKGFNCVLLEKPETCPERVFSVIVKLCWSKE---RKTFAQVHKEL
   | ||.   | | |||. ||..   .  |.  .  .|||.  ..|   . ||.|..||. |. . .. || .|   |..  ..|. .
SIMYRKFTYESDVWSFGVVMWECFTYGKQ-PWYQLSNHEVIECIHQG--RHRLERPRRCPQEVYDIMLG-CWQREPQQRMNIKDIHDII
Kinase AqueK257.AA Ror 482-661 42 1e-52 181.49 In-house 29-215 (308) Show / Hide 
Range on Protein: 482-661
Range on HMM: 29-215/308
Sequence Identity: 42% (81 aa)

TVRVAVKKIRENQSDESIIALKKEIKFMSQLDHNNVVRLLAVSAESCQEQFIVM--EYMENGDLNKFLMDHSF-------TDSHPPEENELSPNILLSFC
.  ||.|. ... |      ...||. |..|.| |.| || |     ..|   |  ||| .|||  ||  .|        .|    .   |..   |   
CMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGV---CTMDQPYCMLFEYMNHGDLHEFLIMRSPHSDHGCSSDDDRMVKSSLDHPDFLHIA

IQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDSSYYKVSGKAKMPIRWMAKEC-FYGKFSEVTDLWAFGVTVWEIY
||.| || ||||. |.||||| ||.|||    ||. ||||.|  | | ||.. .|. ||||||..|   ||||||  | | |||. |||.
IQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIW
Kinase AqueK257.AA Abl 485-723 38 3.9e-50 165.19 In-house 27-252 (252) Show / Hide 
Range on Protein: 485-723
Range on HMM: 27-252/252
Sequence Identity: 38% (95 aa)

VAVKKIRENQSDESIIALKKEIKFMSQLDHNNVVRLLAVSAESCQEQFIVMEYMENGDLNKFLMDHSFTDSHPPEENELSPNILLSFCIQVANGMSYLSS
|||| ..|.. .  .    ||   | .. | |.|.|| |        .|. |.| .| |  .| .         ...||.. .||    |.| ||||| .
VAVKTLKEDTME--VHEFLKEAAIMKEMKHPNLVQLLGVCTREP-PFYIITEFMCYGNLLDYLREC--------DREELPAVVLLYMATQIASGMSYLEK

RNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDSSYYKVSGKAKMPIRWMAKECF-YGKFSEVTDLWAFGVTVWEI--YMMSRDYPYSFMTDQEVIDNA
|.||||||| || ||| . |||| ||||.| . |  |    | || ||.| | |   | |||   | ||||| .|||  | ||   ||  .  ..| .  
RHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAG-AKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMS---PYPGIDLSHVYHKL

LKGFNCVLLEKPETCPERVFSVIVKLCW---SKERKTFAQVHKEL
 ||.    .|.|| ||. |. .. . ||     .| .|...|...
EKGYR---MERPEGCPPKVYELMRQ-CWQWSHTDRPSFKEIHHAM
Kinase AqueK257.AA Musk 485-723 36 5.9e-50 163.15 In-house 32-282 (282) Show / Hide 
Range on Protein: 485-723
Range on HMM: 32-282/282
Sequence Identity: 36% (93 aa)

VAVKKIRENQSDESIIALKKEIKFMSQLDHNNVVRLLAVSAESCQEQFIVMEYMENGDLNKFL------MDHSFTDSHP--------PEENELSPNILLS
||||  ... |..     . |   | . || |.|.|| | .   .     .|||  |||| ||        .| | . .        |   .|.   .| 
VAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCF-VGRPMCLLFEYMAYGDLNEFLHSCSPHRTCSRTHQDRGMRAQVSSPGPPQLKCYHQLC

FCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDSSYYKVSGKAKMPIRWMAKEC-FYGKFSEVTDLWAFGVTVWEIYMMSRDYPY
   |.| || ||| . |.||||| || |..    ||. ||||||. |   |||  .    |||||. |  .| .|.   | ||.||  |||.      ||
MAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYALQ-PY

SFMTDQEVIDNALKGFNCVLLEKPETCPERVFSVIVKLCWSK---ERKTFAQVHKEL
  ||  |||     |.    |  || ||  |.  . ..||.|   .|  |.|.|. .
YGMTHEEVIYYIRQGN---ILSCPENCPQKVYQ-LMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK257.AA CTKA 485-723 34 9.3e-50 165.3 In-house 37-290 (290) Show / Hide 
Range on Protein: 485-723
Range on HMM: 37-290/290
Sequence Identity: 34% (90 aa)

VAVKKIRENQSDESIIALKKEIKFMS--QLDHNNVVRLLAVSAESCQEQFIVMEYMENGDLNKFLMDHSFTDS----------------HPPEENELSPN
|||| ....  .|   |   |    |  ...| ||.||| |   . .  . .||.|  |||  .|   .  ..                ||    |..  
VAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQH-KPWHMIMEHMQYGDLHCYLR-ACRPADGQVCPARARRSIPRSFHP---IEVHAH

ILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDS-SYYKVSGKAKMPIRWMAKECF-YGKFSEVTDLWAFGVTVWEIYMMS
   .   |.| ||.||... |.||||| ||.|.|    .|. |||..| |     || || .  ||.|||| |    ||||   | ||||| .|||  | 
EQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMG

RDYPYSFMTDQEVIDNALKGFNCVLLEKPETCPERVFSVIVKLCWS---KERKTFAQVHKEL
   |.  |.||||  .|  .     |  | .||. |     ..||    ..| ||... ..|
E-KPWRHMSDQEVC-QAYTSHGMRRLPVPRNCPQ-VLYHCMQECWKFEPNQRPTFETLQRML
Kinase AqueK257.AA S_TKc 443-730 18 1.1e-30 109.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 443-730
Range on HMM: 1-231/231
Sequence Identity: 18% (56 aa)

FEEIALLGTGQFGEVVLAKTIGLSLKDLRLDKTDDDKFATVRVAVKKIRENQSDESIIALKKEIKFMSQLDHNNVVRLLAVSAESCQEQFIVMEYMEN--
.| . ..| | ||.| ... ..                   .||.|.|.        . ...||. ... .| |.|.|. |  .  .. ..||||...  
YEILRKIGKGAFGKVYKCRHKK----------------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDL

GDLNKFLMDHSFTDSHPPEENELSPNILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIVKVGDFGLSRNLYDSSYYKVSGKAKMPIRWMAKECF
||| ... ..     .      ...    ... |..... |. |...|||||   |||.     .|..||||.| |                 .|| | .
GDLFDYIKKRGRHGLR----FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL

YGKFSE-VTDLWAFGVTVWEIYMMSRDYPYSFMTDQEVIDNALKGFNCVLLEKPETCPERVFSVIVKLCWSKE---RKTFAQVHK--ELVHADQRL
  ...    | |..|....|  |...  |..  ..|..... .              .. . . ... |. |.   | |  .. .  ... ... .
--GYGKCKCDWWSCGCILYE--MLCGYPPFP--QMQMMFKKIG--------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK257.AA Pkinase 443-659 22 6.6e-29 103.28 Pfam 1-204 (293) Show / Hide 
Range on Protein: 443-659
Range on HMM: 1-204/293
Sequence Identity: 22% (54 aa)

FEEIALLGTGQFGEVVLAKTIGLSLKDLRLDKTDDDKFATVRVAVKKIRENQSDESI-IALKK--EIKFMSQLDHNNVVRLLAVSAESCQEQFIVMEYME
.. .  .| | ||.| ... .| .                 .||||.|.    ...  ... .  ||. |  |.| |.|||. .  .  ..  .||||.|
YHIGRKIGSGSFGCVYKCHHKGTGK----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCE

NG----DLNKFLMDHSFTDSHPPEENEL--SPNILLSFCIQVANGMSYLSSRNFIHRDLASRNILVGPDYIV----KVGDFGLSRNLYDSSYYKVSGKAK
.|    ||  ...          ... .  |.. . ... |.. |. |. |...||||| . |||.  .. .    |..||||.. ..    |  .. ..
GGLYVMDLFDYIST--------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MT

MP---IRWMAKEC--FYGKFSEVTDLWAFGVTVWE
 .   ...|| |   .. . .   | |..|....|
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYE
Kinase AqueK257.AA Src 443-457 53 0.038145 3.03 In-house 1-15 (255) Show / Hide 
Range on Protein: 443-457
Range on HMM: 1-15/255
Sequence Identity: 53% (8 aa)

FEEIALLGTGQFGEV
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IKLCRKLGQGQFGEV