Gene AqueK258 (A.queenslandica)

AqueK258

Species: A.queenslandica
Alias: AqueK258
External Links:
Annotation:

Classification

Group: TK
Family: DDR

Sequence

Name Sequence Type Origin Length Description Download
AqueK258.AA Protein None 996 None Fasta, JSON
AqueK258.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of AqueK258.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IG AqueK258.AA IG 218-315 16 1.7e-08 35.49 SMART 1-58 (58) Show / Hide 
Range on Protein: 218-315
Range on HMM: 1-58/58
Sequence Identity: 16% (17 aa)

LQPHTVQ--SSLNLSCTVDNNGTFHWTWSGPEVSTGDIKLADTTRTSILMISNVSADDA---GNYTCTAFYLAFGDFVGPPNNVFNSIKPDMETTN--SV
 . .||.  ....|.| |    ...|.                     | | ||...|.   |.|.|.|                      ....   ..
PP-VTVKEGETVTLTC-VS---QIWWY---------------------LTI-NVQPEDSQQHGTYYCQAT--------------------HGQYWSIQGT

SLTLF
 || .
TLTVQ
I-set AqueK258.AA I-set 264-281 66 9.4e-05 18.65 Pfam 60-77 (92) Show / Hide 
Range on Protein: 264-281
Range on HMM: 60-77/92
Sequence Identity: 66% (12 aa)

LMISNVSADDAGNYTCTA
|.|||| .||.| |||.|
LTISNVQPDDEGKYTCVA
IGc2 AqueK258.AA IGc2 222-286 23 0.000656 12.37 SMART 1-56 (56) Show / Hide 
Range on Protein: 222-286
Range on HMM: 1-56/56
Sequence Identity: 23% (16 aa)

TVQSSLNLSCT--VDNNGTFHWTWSGPEVSTGDIKLADTTRTSILMISNVSADDAGNYTCTAFYLAF
    |. | |    . . ..||.  | ...            . | |.||. .|.|.|||.|   . 
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP----------WNWTLTIKNVTPEDSGYYTCYARNPWG
IG AqueK258.AA IG 332-428 19 1.1e-08 36.11 SMART 1-58 (58) Show / Hide 
Range on Protein: 332-428
Range on HMM: 1-58/58
Sequence Identity: 19% (20 aa)

GNTVTVQKDTNVTLSCIFTGYLPMDYQINWMDSSNMADGTITNGDDTRNISQSGGSSPGPAVQSNYTILSVEVDDS---DSYTCSMD-GTRLK-ETISLI
   |||.   .|||.| ..       || |.                                   || .|...||     |.|    |.  . ... |.
PP-VTVKEGETVTLTC-VS-------QIWWY----------------------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLT

VI
| 
VQ
I-set AqueK258.AA I-set 398-412 53 1.509746 4.37 Pfam 61-75 (92) Show / Hide 
Range on Protein: 398-412
Range on HMM: 61-75/92
Sequence Identity: 53% (8 aa)

TILSVEVDDSDSYTC
||. |. ||. .|||
TISNVQPDDEGKYTC
TyrKc AqueK258.AA TyrKc 705-986 37 1.5e-116 394.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-280/280
Sequence Identity: 37% (117 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEADDKMREMFEKEVKFMARL--RHENVVRLLGVCLS--------KNAFIM
|. .| || |.||.|....                     . ||.| |...|    ||.| .| . | .|  .|.|.|||.|||..        .  .| 
ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

MEYMENGDLNHYLRNMDLIEDINPLPEGAVSLPVLIYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFGMSQNLYSD-------FYYRI--
||||..|||..|||.              .... |...|.|.|.|| ||.| ..||||||.||.||| .. |||.|||.| ..|.|        |||   
MEYMPHGDLKDYLRKHRPK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKE

--QGRAILPIRWMANECF-YGRFSEKTDVWSFGVLMWEIFTLCKLQPFER----MTDQEVIDDAIKGSERTLPYQ--PQA----CPNEVYSVMLDCWIHE
  .|.. ||||||| ||. ||.|..|.|||||||.||||||...  . .     |..|||| .  .|  .  |    |      || |.|..|..|| ..
HKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHED

PEERASFQQIYDLL
||.| .|..|....
PEDRPTFSEIHECF
Pkinase_Tyr AqueK258.AA Pkinase_Tyr 705-986 39 1.6e-109 371.59 Pfam 1-270 (270) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-270/270
Sequence Identity: 39% (116 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEADDKM--REMFEKEVKFMARL-RHENVVRLLGVCL--SKN--AFIMMEY
|. .| || |.||.|....                . .  . ||.| |.  |...   ||.| .|.| |  | .|.|.|||.|||.  ..    .| |||
ITFGKKLGEGAFGEVYKGTWKG------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY

MENGDLNHYLRNMDLIEDINPLPEGAVSLPVLIYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFGMSQNLYSDFYY-RIQGRAILPIRWM
|..||| .|||.          ........ |. .|.|.|.|| ||.| ..||||||.||.||. ...|||.|||..  .|.| || | .| . |||.||
MPHGDLLDYLRKHR-------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM

ANEC-FYGRFSEKTDVWSFGVLMWEIFTLCKLQP-FERMTDQEVIDDAIKGSERTLPYQPQACPNEVYSVMLDCWIHEPEERASFQQIYDLL
| || .||.|..|.||||||||||||||... || .. |...||..   .  .|    .|. || |.|..|..|| ..||.| .|..|.  |
APECINYGKFTTKSDVWSFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK258.AA TK 705-986 23 2.4e-105 354.21 In-house 1-486 (486) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-486/486
Sequence Identity: 23% (116 aa)

IRELKDLGMGQFG---VVVLAHTVSLSLKQL---------GMSESNNDPGVSLVVAIKRLRAEADDKMREMFE-------------KEVKFMARLR----
|. .| || ||||   .| ..   ... ..           .   |   |.   ||.| |...... ..|.|.             .|.  |. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENVVRLLGVCLSKN-------------AFIMMEYMENGD----LNHYLRNMDLIEDINPL--------------------------------------
 |.|.|||.|||. .                |.||||..||    | .|||. .  .  ..                                       
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------------------------PEGAVSLPVLIYICLQVARGMCYLASL------RFIHRDLATRNILVGQDFK-----------VKIADFGMS-
                           . . .... |. .|.|.|.|| ||.|.      .|.|||||.||.|||.. .           .||||||.| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------QNLYSDFYYRIQG------------------------RAILPIRWMANECFY----------GRFSEKTDVWSFGVLMWEIFTLCKLQPFERM
         .||| .|. ..                        .. ||||||| ||.           |.|..|.||||||||||||||... .. . |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------QEVIDDAIKG-----------SERTLPYQPQACP--------------NEVYSVMLDCWIHEPEERASFQQIYDLL
..         |||..   .|            .|  . ||. ||               |.| .|..|| ..||.| .|.|... |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK258.AA DDR 705-986 39 6e-104 351.64 In-house 1-306 (306) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-306/306
Sequence Identity: 39% (121 aa)

IRELKDLGMGQFGVVVLAHTVSLS-LKQLGMSESNNDPGVSLVVAIKRLRAEADDKMREMFEKEVKFMARLR-HENVVRLLGVCLSKNAFIM-MEYMEN-
 . .. .| |||| | |  . ..  ... .   .    |  . || | ||..| .  |  | ||.| |.... | |.|||.|||.      | |||||| 
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCD-VHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENL

GDLNHYLRNMDLI--------EDINPLPEGAVSLPVLIYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFG--MSQNLYSDFYYRIQG---
|||| ..    .          | .   .  .| . ..||| |.| || ||.|..|.||||||||.||| .. .||.|||  || ||||  |||..|   
GDLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTG

--RAILPIRWMANEC-FYGRFSEKTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDDA----IKGSERTLPYQPQACPNEVY-SVMLDCWIHEPEERASF
  |. .|||||| |.   | |. |.|||.||| |||.|..|. ||.|..||  ||. |     ...  ... .| .|| |.|   |. ||  ....| ||
RQRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSF

QQIYDLL
..|  .|
EEIHKFL
Kinase AqueK258.AA Trk 705-986 39 7.9e-88 297.82 In-house 1-275 (275) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-275/275
Sequence Identity: 39% (115 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEADDKMREMFEKEVKFMARLRHENVVRLLGVCLSKNAFIMM-EYMENGDL
|.  ..|| | ||.|.||    |. .|  |           .||.| |.  .. . |. |..| . .  | |...|.. |||   . ..|  |||..|||
IVLKWELGEGAFGKVFLAECYNLCPEQDKM-----------MVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDL

NHYLRN----MDLIEDINP-LPEGAVSLPVLIYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFGMSQNLYS-DFYYRIQGRAILPIRWMA
|.|||      ... . .|    |   .  . .|  |.| || |.||. |.|||.|||| ||||.  |||.|||||  .||   |||. ..  |||||| 
NKYLRQHGPDAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMP

NEC-FYGRFSEKTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDDAIKGSERTLPYQPQACPNEVYSVMLDCWIHEPEERASFQQIYDLL
 |   | .|.   ||||||| |||.||  | ||.  .  .|||.   .| .|  . .|..|| ||| .|| ||  ||..| .  .|.|..
PESIMYRKFTYESDVWSFGVVMWECFTYGK-QPWYQLSNHEVIECIHQGRHR--LERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase AqueK258.AA TK-Unique 705-986 34 2.8e-80 273.0 In-house 1-294 (294) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-294/294
Sequence Identity: 34% (106 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEADDKMREMFEKEVKFMARLR-HENVVRLLGVCL-SK-NAFIMMEYMENG
.. .. .|.|.|| |  .  ....           . .   .||.| |...|.|  . .| || ..|  |  |.|.|..||.|  |  . .|.|||...|
LEVGDVIGEGAFGQVWRGEVWGIW----------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCG

DLNHYLRNMDLI-----------EDINPLPEGA----VSLPVLIYICLQVARGMCYLAS--LRFIHRDLATRNILVGQDFKVKIADFGMSQNLYSDFYYR
.| ||||..              .|    |..     .|.  |. .. |.|.|| ||||   ...||||..||.|.. |...||.||||.  .| .  | 
NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYS

IQ-GRAILPIRWMANECFY---GRF-SEKTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDDAIKGSERTLPYQPQAC-PNEVYSVMLDCWIHEPEERAS
 . ..  .|||||| | ..   | . ..|.||||||||||||||| . .|. .| . .....  .|.    . ||. | ..|.|..|  || .||||| |
MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKDIMECIRDGYR---MPQPEHCCSHEMYNLMKSCWQWEPEERPS

FQQIYDLL
| || . |
FRQIKHRL
Kinase AqueK258.AA UTK 705-986 33 7.8e-77 261.57 In-house 1-296 (296) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-296/296
Sequence Identity: 33% (103 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEAD-DKMRE---MFEKEVK---FMARLR-HENVVRLLGVCLSKNAFIM-M
.. ...|| |.||.| .|. .  |           ...  ..||.| ....||  . .|    | .| .   .|.... |.||.||.|||..   ... .
VQLGRQLGQGAFGEVHKARFTQCS-----------EHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVT

EYMENGDLNHYLRNMDLIEDINPLPEGAVSLPVLIYICLQVARGMCYLASLRFIHRDLATRNILVGQD-------FKVKIADFG---MSQNLY-------
|||||||| .|||.     .    .. ...|  ... ....|||| ||.| .|.||||| ||.||...        ..||||||   || ...       
EYMENGDLRSYLRRHRPTPP---ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNR

--SDFYYRIQGRAILPIRWMANECFYGR--FSEKTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDDAIKGSERTLPYQPQACPNEVYSVMLDCWIHEPE
  .. ||. |.. ..|||||| |... .  |..|.|||||||..|||.|  .| |.. |....|.    .|. . .| .|..|| .|| .|..||  .|.
YWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRL-PYPGMSNMQVWHQVCNGGRYRMP-CPWDCPHPVYRLMHRCWHYDPQ

ERASFQQIYDLL
|| .|..... .
ERPDFEDLVQQM
Kinase AqueK258.AA CTKA 747-986 37 3.6e-69 231.54 In-house 37-290 (290) Show / Hide 
Range on Protein: 747-986
Range on HMM: 37-290/290
Sequence Identity: 37% (97 aa)

VAIKRLRAEADDKMREMFEKEVKFMA--RLRHENVVRLLGVCL-SKNAFIMMEYMENGDLNHYLRNMDLIE--------------DINPLPEGAVSLPVL
||.| |...| .  |. |  |.   .   . | ||.||||||. .|  .  ||.|  |||  |||                       |.   .|. .  
VAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYLRACRPADGQVCPARARRSIPRSFHPI---EVHAHEQ

IYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFGMSQNLYSD-FYYRIQGRAILPIRWMANECF-YGRFSEKTDVWSFGVLMWEIFTLCKL
.|   |.| || |||.. |.||||| ||.|.||   .|||||| .  | .   || .. . ..|.|||| |    |.||   |||.||||.|||..  ..
VYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEK

QPFERMTDQEVIDDAIKGSERTLPYQPQACPNEVYSVMLDCWIHEPEERASFQQIYDLL
 |. .|.||||      .  | ||  |  ||  .|. |  ||  || .| .| ..   |
-PWRHMSDQEVCQAYTSHGMRRLPV-PRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase AqueK258.AA Src 747-986 40 4.3e-69 233.87 In-house 26-255 (255) Show / Hide 
Range on Protein: 747-986
Range on HMM: 26-255/255
Sequence Identity: 40% (99 aa)

VAIKRLRAEADDKMREMFEKEVKFMARLRHENVVRLLGVCLSK-NAFIMMEYMENGDLNHYLRNMDLIEDINPLPEGA-VSLPVLIYICLQVARGMCYLA
||.| |..       |.| .| . |  ||||..|.|. ||  .   .|  |||..| |  ||..          .||  ..|| ||..  |||.||.|| 
VAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK---------DGEGRHLHLPQLIDMAAQVAEGMAYLE

SLRFIHRDLATRNILVGQDFKVKIADFGMSQNLY--SDFYYRIQGRAILPIRWMANECF-YGRFSEKTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDD
| ..|||||| ||.|||..  .|.||||  . .    | |   .| | .||.|.| |.. ||||. |.||||||.|..||.|  .  | . || .||.. 
SMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHG-AKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV-PYPGMTNHEVLQQ

AIKGSERTLPYQPQACPNEVYS-VMLDCWIHEPEERASFQQIYDLL
  .|    .| .|. || |.|  .|| ||  .||.|  |  ... |
VERGYR--MP-CPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK258.AA Tec 767-991 40 6.1e-63 215.42 In-house 44-254 (254) Show / Hide 
Range on Protein: 767-991
Range on HMM: 44-254/254
Sequence Identity: 40% (92 aa)

EVKFMARLRHENVVRLLGVCLSKN-AFIMMEYMENGDLNHYLRNMDLIEDINPLPEGAVSLPV--LIYICLQVARGMCYLASLRFIHRDLATRNILVGQD
| | |  | |.. |.| |||. .   .|  ||||.| |  ||| .          ..  .  .  |...|..|  || || .  ||||||| || |||..
EAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREH----------KHHFQKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQ

FKVKIADFGMSQNLYSDFYYRIQGRAILPIRWMANECF-YGRFSEKTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDDAIKGSERTLPYQPQACPNEVY
  ||..||||.     | |    | .  |..| . | | | |.| | |||.|||||||.|.. | .|.|.|.  ||...  .|    | |.|. |....|
CVVKVSDFGMTRYVLDDQYTSSVG-TKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGK-MPYENMSNSEVVEHVSQG--HRL-YRPHLCSMHIY

SVMLDCWIHEPEERASFQQIYDLLSSIHA
 .| .|| ..|||| .|||   ||..|  
QIMYHCWHEKPEERPTFQQ---LLRQITE
Kinase AqueK258.AA Musk 835-986 43 8e-51 166.06 In-house 134-282 (282) Show / Hide 
Range on Protein: 835-986
Range on HMM: 134-282/282
Sequence Identity: 43% (66 aa)

QVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFGMSQNLYSDFYYRIQGRAILPIRWMANEC-FYGRFSEKTDVWSFGVLMWEIFTLCKLQPFERM
|.| || ||   .|.|||||||| |..    |||||||.|.. |.  ||. ..    |||||. |  .| .|.   |||..||..||||    |||.  |
QIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYA-LQPYYGM

TDQEVIDDAIKGSERTLPYQPQACPNEVYSVMLDCWIHEPEERASFQQIYDLL
|  |||     |        |  || .|| .|  ||  .| .| .|.|| . .
THEEVIYYIRQGNILSC---PENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK258.AA Ror 830-982 46 2.8e-50 173.35 In-house 122-271 (308) Show / Hide 
Range on Protein: 830-982
Range on HMM: 122-271/308
Sequence Identity: 46% (72 aa)

IYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFGMSQNLYSDFYYRIQGRAILPIRWMANEC-FYGRFSEKTDVWSFGVLMWEIFTLCKLQ
..| .|.| || ||.|  |.|||||.||.|||   .|||.||| .   ||  |||.|.....|||||. |   ||.|||  |.|||||  |||.    .|
LHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIWSYG-MQ

PFERMTDQEVIDDAIKGSERTLPYQPQACPNEVYSVMLDCWIHEPEERASFQQI
|..    |||| . |    | |   |  ||  .|| |  ||   |. |  |  |
PYYGYSNQEVI-EMIR--NRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDI
Kinase AqueK258.AA S_TKc 705-993 21 1.7e-36 128.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 705-993
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEADDKMREMFEKEVKFMARLRHENVVRLLGVCLSKNAFIMMEYMEN--GD
 . |. .| | ||.| ... ..                   .||||...        |....|.. . . .|.|.|.|..|. ... .. |||...  ||
YEILRKIGKGAFGKVYKCRHKK----------------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGD

LNHYLRNMDLIEDINPLPEGAVSLPVLIYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKVKIADFGMSQNLYSDFYYRIQGRAILPIRWMANECFY
| .|....       |.||  .      ... |..... |. |...|||||   |||. .   .||.|||..  |            .    .|| | . 
LFDYIKKRGRHGLRFPFPE-HA-----RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL-

GRFSE-KTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDDAIKGSERTLPYQPQACPNEVYSVMLDCWIHEPEERASFQQIYD--LLSSIHAYN
  ..  | |.||.|....| ..     ||.  ..|....                 . |. . .  |.  .||.| .  ..    ..  .| . 
-GYGKCKCDWWSCGCILYEMLC--GYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK258.AA Pkinase 705-986 20 4.9e-35 124.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 705-986
Range on HMM: 1-293/293
Sequence Identity: 20% (68 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEADDK-MREMFEK--EVKFMARLRHENVVRLLGVCL-SKNAFIMMEYMEN
.. .. .| | ||.| ..| .. .                 .||.|... . ... ...   .  |.. |.||.|.|.|||....  ...  . |||.|.
YHIGRKIGSGSFGCVYKCHHKGTGK----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEG

G----DLNHYLRNMDLIEDINPLPEGAV--SLPVLIYICLQVARGMCYLASLRFIHRDLATRNILVGQDFKV----KIADFGMSQNLYSDFYYRIQGRAI
|    || .|..            .|..  |  ... ...|..||. |. | ..|||||   |||. ..  .    ||.||| .  ..   | . .    
GLYVMDLFDYIST---------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTT

LP--IRWMANEC--FYGRFSEKTDVWSFGVLMWEIFTLCKLQPFE------RMTDQEVIDDAIKGSERTLPYQPQ------------------ACPNEVY
.   ...|| |   ..   . | |.||.|....| ..  .  ||       .  || .. . |.| .   ...                    . . |  
FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC--GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECK

SVMLDCWIHEPEERASFQQIYDL--L
... .|.   |..| ...||     .
DFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK258.AA Musk 705-810 32 5.8e-20 62.44 In-house 1-96 (282) Show / Hide 
Range on Protein: 705-810
Range on HMM: 1-96/282
Sequence Identity: 32% (35 aa)

IRELKDLGMGQFGVVVLAHTVSLSLKQLGMSESNNDPGVSLVVAIKRLRAEADDKMREMFEKEVKFMARLRHENVVRLLGVC-LSKNAFIMMEYMENGDL
|   .|.| | || |  |    |   .             ..||.| |...|...| . |. |   ||.  | |.|.||||| . .    ..|||  |||
IIYVRDIGEGAFGRVFQARAPGLVPYE-----------EETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDL

NHYLRNM
| .|. .
NEFLHSC
Kinase AqueK258.AA Ror 747-803 43 6.6e-16 59.17 In-house 32-89 (308) Show / Hide 
Range on Protein: 747-803
Range on HMM: 32-89/308
Sequence Identity: 43% (25 aa)

VAIKRLRAEADDKMREMFEKEVKFMARLRHENVVRLLGVCLSKNAFIMM-EYMENGDL
|||| .. .|  . .. |..|.. ||.| | |.| |||||. ..   |  ||| .|||
VAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDL
Kinase AqueK258.AA Tec 705-722 55 0.001374 8.5 In-house 1-18 (254) Show / Hide 
Range on Protein: 705-722
Range on HMM: 1-18/254
Sequence Identity: 55% (10 aa)

IRELKDLGMGQFGVVVLA
.  .| || |||||| |.
LTFMKELGSGQFGVVHLG