Gene AqueK265 (A.queenslandica)

AqueK265

Species: A.queenslandica
Alias: AqueK265
External Links:
Annotation:

Classification

Group: TK
Family: EGFR

Sequence

Name Sequence Type Origin Length Description Download
AqueK265.AA Protein None 1091 None Fasta, JSON
AqueK265.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of AqueK265.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Recep_L_domain AqueK265.AA Recep_L_domain 45-161 31 7.4e-22 75.21 Pfam 1-121 (121) Show / Hide 
Range on Protein: 45-161
Range on HMM: 1-121/121
Sequence Identity: 31% (40 aa)

GCRYIKDNIVIQTGPTLVDANQTLVEANFSFLYYVKEISGYLELNGI-PSIERLSLPNLRIIRGRNLRSG-RYSLLAL--GK--IQNLYMPNLTEISR--
.|. |. |..|.   .  .      | ..||.  ..||.|||....  .      .|||||||||.|  . .|.|  .   .  .| |.|.||..|.|  
NCTVIYGNLEITWRDEHNE-----LEEDLSFFPNIREITGYLLIYRTYNLKNLSFFPNLRIIRGRQLFHDDNYALYIYDNPNMGLQELWMWNLKNITRKN

GDVWFISRLNPYLCNTRS-INWIDIA
|.| .    .| ||.|.. |.| .| 
GGVYIHNNPHPKLCYTHTEIMWWMIY
Furin-like AqueK265.AA Furin-like 226-315 30 8.8e-22 72.04 Pfam 83-182 (182) Show / Hide 
Range on Protein: 226-315
Range on HMM: 83-182/182
Sequence Identity: 30% (31 aa)

VACKNVLNDGVCRERCPEQYIIDPDTRAVVLNPEFKFEA-QPLCV--STCP--------AMLFELGTQCVEDCPSNYMSVSGDNGTMRCVLCDGPCPQEC
|||... ..|.| ..||   | .|.|  ...||. ...     ||  ..||          .   ...|. .|||.|. .   |.|| |. |.|||| .|
VACRHFYHNGTCVDQCPPMMIYNPTTFQMEPNPDGTYQFEGWRCVTFKECPKLSHNPDCNYYVIHNGECMRECPSGYTENE-ENNTMMCEPCEGPCPKVC

A
 
Y
Recep_L_domain AqueK265.AA Recep_L_domain 329-450 21 1.9e-09 33.46 Pfam 1-121 (121) Show / Hide 
Range on Protein: 329-450
Range on HMM: 1-121/121
Sequence Identity: 21% (30 aa)

GCTIITTELRISSVPPNLDPSILND----LNEIREIRGSLDISGF-NKETFPYLYNLKTVGNND--SNQVLSQSCNGSSDSFKYSIIIADTE---LVSID
.||.|   |.|...  . .   |..    .  ||||.|.| | .  |   .  . ||...  .    .              .|...| |     | ...
NCTVIYGNLEITWRDEHNE---LEEDLSFFPNIREITGYLLIYRTYNLKNLSFFPNLRIIRGRQLFHD-------------DNYALYIYDNPNMGLQELW

LSSLEAVIN--GGVRLQNNP--SLCYLGD-LRYYLTN
. .|. ...  |||. .|||   |||.   .. ....
MWNLKNITRKNGGVYIHNNPHPKLCYTHTEIMWWMIY
FU AqueK265.AA FU 471-518 28 2e-06 28.31 SMART 1-48 (48) Show / Hide 
Range on Protein: 471-518
Range on HMM: 1-48/48
Sequence Identity: 28% (15 aa)

TNMT--CHPQCSSASGWCWGPNDTQCVTCTNFIFN---GQCVPTCNDFDAHGV
...   |||.|..    ||||...||..| .. .    |.||..|.  . .  
DGVCKPCHPECAT---GCWGPGPDQCTSCPHGYYLHHNGTCVSQCP--PGYYP
FU AqueK265.AA FU 526-578 26 2e-06 28.65 SMART 1-48 (48) Show / Hide 
Range on Protein: 526-578
Range on HMM: 1-48/48
Sequence Identity: 26% (14 aa)

NNTCLACHSFCSGSCVGEGPANCSSSCNTNFFVNVSVGVGIQCLESCVGDTYL
...| .||. |.. |.| || .|. || . .. .       .|...|   .| 
DGVCKPCHPECATGCWGPGPDQCT-SCPHGYYLHHN----GTCVSQCPPGYYP
FU AqueK265.AA FU 584-642 33 8.2e-05 23.24 SMART 1-48 (48) Show / Hide 
Range on Protein: 584-642
Range on HMM: 1-48/48
Sequence Identity: 33% (20 aa)

SGECLPCFSGCSLGYGCAGPGKTFNDSNGCMAC-DTILLDRNGDQIECQRDVTCPSGYYW
.|.| || ..|.   || |||      . | .|    .|. |    .|    .||.|||.
DGVCKPCHPECAT--GCWGPG-----PDQCTSCPHGYYLHHN---GTCVS--QCPPGYYP
FU AqueK265.AA FU 656-702 32 0.010111 14.8 SMART 1-48 (48) Show / Hide 
Range on Protein: 656-702
Range on HMM: 1-48/48
Sequence Identity: 32% (16 aa)

TVLCHSCHELCAT-CSGPSVSDCVLC-SYIRGTN-GSCVFMCDPIRETVP
.  |. ||. ||| |.||   .|. | ..  . . | ||  |     . |
DGVCKPCHPECATGCWGPGPDQCTSCPHGYYLHHNGTCVSQCP--PGYYP
Kinase AqueK265.AA EGFR 805-1061 48 3.5e-128 427.79 In-house 1-258 (258) Show / Hide 
Range on Protein: 805-1061
Range on HMM: 1-258/258
Sequence Identity: 48% (126 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVL-KNTSASASKELLQEGVVMATMDHENVVRLYCVCMSKQLMLVSQFVPCGALIDYIKKQQDRLNA
|  .| ||.||||||| | | |  ..    |||||| ..|...|..|.|.|  ||| .||...||| .|||..|..|| |. | |.| ||... .|.. .
LKKVKVLGSGAFGTVYKGIWIPEGENVKIPVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQMQLVTQYMPYGCLLDYVRQHKDNIGS

HTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEANQSHYEATTSKMPVRWLPPESIRNRVFTHKTDVWSFGVTVWEILTFG
.  |... ||| || ||| ...||||||||||||..| .|||||||| .. |...  |.|   |||..|.  |.|..|..||. ||||.|||.||..|||
QHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGGKMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFG

ARPYQGKKPYEILKMLEGGHRLDQPVTCTIDLYAVLLECWLLEPDSRPDFVDLGRRFH
..||.| .  ||  .|| | || ||  ||||.| |.. ||.. .|.|| |  |  .|.
QKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase AqueK265.AA Pkinase_Tyr 805-1060 39 1.1e-122 416.13 Pfam 1-270 (270) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-270/270
Sequence Identity: 39% (106 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNTSASA---SKELLQEGVVMATM-DHENVVRLYCVCM--SKQ--LMLVSQFVPCGALIDYIKK
..|||.||.||||.||.|.||.  |.....||.|.||... .    ......|  .| .. .|.|.|||| ||.  ...  ...|  ..|.| | || .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Q---QDRLNAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEANQSHY-EATT-SKMPVRWLPPESIRNRVFTHKTDVWS
.   ...|. ...| .. |||.||.||| |...||||||||.||  . .|||.||||.| |  | . |  ... .|.|..|..||.|....||.|.||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGVTVWEILTFGARP-YQGKKPYEILKML-EGGHRLDQPVTCTIDLYAVLLECWLLEPDSRPDFVDLGRRF
|||. |||.|.|. | |.| ...|..... | |.|...|  |. ..| ....||  .|. || | .. ...
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK265.AA TyrKc 805-1060 36 2.8e-116 393.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-280/280
Sequence Identity: 36% (107 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNTSASASKELLQEGVVMATM--DHENVVRLYCVCMS--------KQLMLVSQFVPCGALIDYI
...||.|| ||||.||.| ||       . ||.|.||. .    .....|  .|     .|.|.|||| ||..        ..||.|  ..| |.| ||.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKQQDRLNAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEAN------QSHYEATT---SK--MPVRWLPPESIRNRVF
.| ...|.  . | |. |||.||.||. |...||||||||.||  .  |||.||||.| |.        .. | ...   .|  .|.||..||.|. ..|
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

THKTDVWSFGVTVWEILTFGARPYQG-----KKPYEILKMLEGGHRLDQPVT--------CTIDLYAVLLECWLLEPDSRPDFVDLGRRF
|.|.|||||||. |||.|.|. || |     ....|... .. |.|..||          |. ..| . ..||  .|..|| | .. ..|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK265.AA TK 805-1060 22 9.1e-105 352.22 In-house 1-486 (486) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

LEFGKELGAGAFG---TVYEGYWKPAN---------------------DENEYHVAIKVLKNTSASASKELLQ--------------EGVVMATMD----
...||.||.|.||   .||.| |.. |                     ....  ||.|.|| ..|....| ..              |  .|. |.    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENVVRLYCVCMSKQ-------------LMLVSQFVPCGA----LIDYIKKQQDR--------------------------------------------
 |.|.|||| ||. ..             .|.|  ..|.|     | || .|  ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNAHTILLFSSQIANGMAYLETK------HLVHRDLAARNVLVQTPVK-----------VKITDFG---
                               |. |. | .. |||.||.||. |      ..|||||||||.||    .           .||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LTRIIEANQSHYEAT------------------------TSKMPVRWLPPESIRNRV---------FTHKTDVWSFGVTVWEILTFGARPYQGKK
     |.| |. ..  | ..                          |.|.||..||... ||         ||.|.|||||||..|||.|.|. || |  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

P----------YEILKMLEGG--------------HRLDQPVTCT--------------IDLYAVLLECWLLEPDSRPDFVDLGRRF
.           |....|. |              .|. ||. |.               ..| ....|| ..|. ||.| .| ...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK265.AA Ack 805-1060 36 2e-92 312.05 In-house 1-266 (266) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-266/266
Sequence Identity: 36% (98 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNT---SASASKELLQEGVVMATMDHENVVRLYCVCMSKQL-MLVSQFVPCGALIDYIKKQQD-
.  ...|| | || |  | |. .. .    ||.|.|.     .  .. ..|.|  .|  .||...|||| |  .  . |.|. . |||.| |  .|..  
ITLCEKLGDGCFGVVWRGEWTNPGGK-HIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRKHCRT

-RLNAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTP-VKVKITDFGLTRIIEANQSHYEATTSK---MPVRWLPPESIRNRVFTHKTDVWSFGV
  .  ||.. |. |||.||.||| |...||||||||.|. ..  |||| |||| |    |  .|     .    |  | .||..| | |.|. |||.|||
AFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGV

TVWEILTFGARPYQGKKPYEILKMLE-GGHRLDQPVTCTIDLYAVLLECWLLEPDSRPDFVDLGRRF
| ||  ..|  |. |  .|.||. ..  | || .|  |  |.|.....||  .|  || |...   .
TLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase AqueK265.AA Syk 805-1054 38 1.1e-88 300.93 In-house 1-257 (257) Show / Hide 
Range on Protein: 805-1054
Range on HMM: 1-257/257
Sequence Identity: 38% (99 aa)

LEFGKELGAGAFGTVYEGYWKPA---NDENEYHVAIKVLK-NTSASA-SKELLQEGVVMATMDHENVVRLYCVCMSKQLMLVSQFVPCGALIDYIKKQQD
|. ..|.| | ||.| .|. .      ..    ||||.||   .  |  .|.. |  ||.  ||  .||.  .|   ..|.|   .. |.. .|... ..
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKADHNQPADKQEFMREAQVMCQLDHPCIVRMIGICHAEMMMMVMEMAELGPMHKYLQQHRH

RLNA-HTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEANQSHYEATTS-KMPVRWLPPESIRNRVFTHKTDVWSFGVTVW
   |   . |  .|.| || ||| || |||||||||||  .    || |||. .   |. . | |||  | ||.|  ||.|  . | || |||||||| |
EITANNVLELWHTQVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMW

EILTFGARPYQGKKPYEILKMLEGGHRLDQPVTCTIDLYAVLLECWLLEPDSRPDFV
| .  |..|| ..|  |..|..| |||. .|  |  ..|..  .||. ..  ||.||
EMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase AqueK265.AA TK-Unique 805-1060 32 2.8e-84 286.3 In-house 1-294 (294) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-294/294
Sequence Identity: 32% (95 aa)

LEFGKELGAGAFGTVYEGYWKPAN-DENEY-HVAIKVLK-NTSASASKELLQEGVVMATMD-HENVVRLYCVCM-SK-QLMLVSQFVPCGALIDYIKKQQ
||.|...| ||||.|. |  .. . ....  .||.| || | .    ...|.|  .|   . |.|.|... .|. |  . |..  ..||| | .|... .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

DR-------------------------LNAHTILLFSSQIANGMAYLET--KHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEANQSHYEATT-SKMPV
.                          .. .. . |  |||.||.||.   |. |||||.|||||..   ..||.|||..| ...|. .   .. ...|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWLPPESIR--NRVF-THKTDVWSFGVTVWEILTFGARPYQGKKPYEILKMLEGGHRLDQPVTC-TIDLYAVLLECWLLEPDSRPDFVDLGRRF
||..|||..   ... | |.|||||||. |||.|.||.|| | .. .|..... |.|..||  | . ..| .. .|| .||..||.| ..  |.
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK265.AA SFK-Src 805-1064 36 1e-83 247.86 In-house 1-259 (259) Show / Hide 
Range on Protein: 805-1064
Range on HMM: 1-259/259
Sequence Identity: 36% (98 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNTSASASKELLQEGVVMATMDHENVVRLYCVCMSKQ-LMLVSQFVPCGALIDYIKK-QQDRLN
 .  | ||.| || |. | |      |   ||.| ||  . || .| |||  ||  . |.| ..|| ||  .  .  ..  .  | | || .  .   |.
IRLEKKLGSGQFGDVWKGRW-----NNTTEVAVKTLKPGAMSA-EEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLR

AHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEANQSHYEATT-SKMPVRWLPPESIRNRVFTHKTDVWSFGVTVWEILT
  .     .|.| |||||| .  ||||||||||||     .|. |||. |......  |.| .  | |..|  ||      |  | ||||||.   || |
MPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVT

FGARPYQGKKPYEILKMLEG--GHRLDQPVTCTIDLYAVLLECWLLEPDSRPDFVDLGRRFHEFM
.|  || |    |.|. ..   | |.. |  |   .|.....||  ||| || |  |  .  .| 
YGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK265.AA Src 805-1060 37 1.8e-83 283.42 In-house 1-255 (255) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-255/255
Sequence Identity: 37% (99 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNTSASASKELLQEGVVMATMDHENVVRLYCVCMSK-QLMLVSQFVPCGALIDYIK--KQQDRL
. . ..||.| || |..|||.     .. .||.|.||  .  . . .|||  .| ...||..|.|| ||  .     |  .   | | || |  ..  .|
IKLCRKLGQGQFGEVWMGYWN-----GNTKVAVKTLKPGT-MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL

NAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEANQSHYEATT-SKMPVRWLPPESIRNRVFTHKTDVWSFGVTVWEIL
.  . . .. |.|.|||||| . ..||||||||||| .   .|. |||| |.|. .   |.| . .|.|..|  || |. ..|| |.||||||.  .|| 
HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIV

TFGARPYQGKKPYEILKMLEGGHRLDQPVTCTIDLYA-VLLECWLLEPDSRPDFVDLGRRF
|.|  || | .  | |...| | |. .| .|   ||  ..|.||  .|. || |  |   .
TYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK265.AA UTK 805-1060 30 7.4e-83 281.57 In-house 1-296 (296) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-296/296
Sequence Identity: 30% (89 aa)

LEFGKELGAGAFGTVYEGYWKPAN-DENEYHVAIKVLKNTSASASK-----ELLQEGV---VMATMD-HENVVRLY-CVCMSKQLMLVSQFVPCGALIDY
...|..||.||||.|... .....  . | .||.||.......  .     ... |     .|.  . |.||.||.  .. ....|.|. . . | |..|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

IKKQQDRLN-------AHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTP-------VKVKITDFG---LTRIIEA--------NQSHYEAT-TSK
  .. . ..        |. | ....||.||.||.....|||||||||.||           ..|| |||   ..| . .        ..  | |.   .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

MPVRWLPPESIRNR-VFTHKTDVWSFGVTVWEILTFGARPYQGKKPYEILKMLEGG--HRLDQPVTCTIDLYAVLLECWLLEPDSRPDFVDLGRRF
.|.||  ||.. ..  ||.|.|||||||..|||.|.|..|| |    .... .. |  .|. .|  |  ..| ....||  .|. ||||.||  ..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK265.AA Fer 805-1061 33 1.3e-81 277.41 In-house 1-283 (283) Show / Hide 
Range on Protein: 805-1061
Range on HMM: 1-283/283
Sequence Identity: 33% (96 aa)

LEFGKELGAGAFGTVYEG----YWKPANDENEYHVAIKVLKN--TSASAS--KELLQEGVVMAT-MDHENVVRLYCVCMSKQ-LMLVSQFVPCGALIDYI
 ..|| || ||||.|| |    . | .   . . ||.|| |.  ..|..   ||...|  .| . .|| |||..| || ..| .|.|  |...|.| .|.
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KKQQDR-LNAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQT-PVKVK--ITDFGLTRIIEANQSHYE-A-TTSKMPVRWLPPESIRNRVFTHKTD
|| ... .   ... .. |.|.||.||. |. .|||.||||.|.    ||.|  |.|||. |  . ... |. . .  |.|.|||.||.........|||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSFGVTVWEILTFGARPYQG----KKPYEI-----LKMLEGGHRLDQPVTCTIDLYAVLL-ECWLLEPDSRPDFVDLGRRFH
||||||. ||| | || || |     |. ..      .  ..|...  |  .  ... ...  ||  .|. || . .. ....
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK265.AA Frk 805-1064 35 4.6e-72 245.71 In-house 1-260 (260) Show / Hide 
Range on Protein: 805-1064
Range on HMM: 1-260/260
Sequence Identity: 35% (94 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNTSASASKELLQEGVVMATMDHENVVRLYCVCMSKQ-LMLVSQFVPCGALIDYIK---KQQDR
... ..||.| || |.|| |     .|.  ||.| ||  ..   ...|.|  .|  . |  ...|| ||  .. ....   .  |.| .|..   ..  .
IQLIRRLGSGQFGEVWEGLW-----NNTTPVAVKTLKPGTMDP-NDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ

LNAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTR-IIEANQSHYEATTS-KMPVRWLPPESIRNRVFTHKTDVWSFGVTVWE
.. ....  . |.| |||||| .  .|||||||||||     .|| |||| | ..  |.  ||. .  ..|..|  || ..   || | ||||||. . |
CQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTE

ILTFGARPYQGKKPYEILKMLEGGHRLDQPVTCTIDLYAVLLECWLLEPDSRPDFVDLGRRFHEFM
|.|.|  || |    |.|.|.. | |. ||  |   || ..||||  .|. || |  |  .. ...
IITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK265.AA S_TKc 805-1064 23 3.9e-53 183.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 805-1064
Range on HMM: 1-231/231
Sequence Identity: 23% (65 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNTSASASKELLQEGVVMATMDHENVVRLYCVCMSKQLMLVSQFVPC--GALIDYIKKQQDR--
 |.....| ||||.|| ...|        .||||..|       . ...|  ..   .|.|.|.|| |. .. | .|  ...   | | |||||.. .  
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LNAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKVKITDFGLTRIIEANQSHYEATTSKMPVRWLPPESIRNRVFTH-KTDVWSFGVTV
   ..  ..  .  ||.....|.  .. .||||   |.|. .   .||.|||| |..         ||      ...|| .    ... | |.||.|...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

WEILTFGARPYQGKKPYEILKMLEGGHRLDQPVTCTIDLYAVLLECWLLEPDSRPDFVDLGRRF-----HEFM
.| |. |  |..   .....|..            . ..   .  |.  .|. ||   .. ..      |...
YEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK265.AA Pkinase 805-1060 22 1e-42 152.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 805-1060
Range on HMM: 1-293/293
Sequence Identity: 22% (69 aa)

LEFGKELGAGAFGTVYEGYWKPANDENEYHVAIKVLKNTSASASKE-----LLQEGVVMATMDHENVVRLYCVCM-SKQLMLVSQFVPCG----ALIDYI
...|. .|.|.||.||....|  ..     ||.|..|  ... .|.     | .|  .|. ..|.|.||||.... .. . .|  ....|     | |||
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

K-KQQDRL--NAHTILLFSSQIANGMAYLETKHLVHRDLAARNVLVQTPVKV----KITDFGLTRIIEANQSHYEATTSKMPVRWLPPESIR-NRVFTHK
. ... ..    ...  .  ||. |..|.  .  .||||   |.|.     .    ||.|||| . .. . .   .||     ....|| || ..  ..|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDVWSFGVTVWEILTFGARPYQGK-------KPYEILKMLEGGHRLDQPVTCT-------------------IDLYAVLLECWLLEPDSRPDFVDLGRR-
 |.||.|....| |. |  |..|.       . . | . ...  . | | .|.                    ..  ..  |. . | .|| . ..    
VDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

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WF