AqueK278

Species: A.queenslandica
Alias: AqueK278
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK278.AA Protein None 640 None Fasta, JSON
AqueK278.kin_dom Protein Kinase Domain None 69 None Fasta, JSON

Protein domain

Protein domains of AqueK278.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK278.AA Pkinase_Tyr 567-635 40 2.7e-26 89.68 Pfam 1-74 (270) Show / Hide
Range on Protein: 567-635
Range on HMM: 1-74/270
Sequence Identity: 40% (30 aa)

ISIAEEIGSGQFGTVFKGVWN--SSCGPIDVAIKKLKENFAEED--KVKFLQEGAIMGQF-HHPSIIQLHGVIT
|.. ...|.|.||.|.||.|.   . . |.||.|.|||.  .|.  . .|..| .|| |. ||| |..|.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT

Kinase AqueK278.AA Eph 567-635 44 1.9e-22 72.13 In-house 1-74 (264) Show / Hide
Range on Protein: 567-635
Range on HMM: 1-74/264
Sequence Identity: 44% (33 aa)

ISIAEEIGSGQFGTVFKGVWNSSCGPIDV-----AIKKLKENFAEEDKVKFLQEGAIMGQFHHPSIIQLHGVIT
| | . ||.|.|| | .|    . |  .|     ||| ||.  .| ... || | .||||| || ||.| ||.|
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVT

Kinase AqueK278.AA SFK-Src 567-637 42 3e-21 59.2 In-house 1-66 (259) Show / Hide
Range on Protein: 567-637
Range on HMM: 1-66/259
Sequence Identity: 42% (30 aa)

ISIAEEIGSGQFGTVFKGVWNSSCGPIDVAIKKLKENFAEEDKVKFLQEGAIMGQFHHPSIIQLHGVITIG
|   .  |||||| |.||.|| .    .||.| ||     ..   |||| ..| .  ||  |||. | |.|
IRLEKKLGSGQFGDVWKGRWNNTT---EVAVKTLKPGAMSAE--EFLQEAQVMKKLRHPNLIQLYAVCTDG

Kinase AqueK278.AA TK 567-638 25 8.4e-20 62.36 In-house 1-116 (486) Show / Hide
Range on Protein: 567-638
Range on HMM: 1-116/486
Sequence Identity: 25% (30 aa)

ISIAEEIGSGQFG---TVFKGVWNS-----------------------SCGPIDVAIKKLKE--NFAEEDKVK-----------FLQEGAIMGQFH----
| . ...|.||||   .|.|| |..                       . |...||.| |||  . ..|..             ||.| ..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPSIIQLHGVITIGV
 || |..|.||.| |.
HHPNIVRLYGVCTQGE

Kinase AqueK278.AA Src 567-635 36 1.2e-17 56.45 In-house 1-64 (255) Show / Hide
Range on Protein: 567-635
Range on HMM: 1-64/255
Sequence Identity: 36% (25 aa)

ISIAEEIGSGQFGTVFKGVWNSSCGPIDVAIKKLKENFAEEDKVKFLQEGAIMGQFHHPSIIQLHGVIT
|   ...|.|||| |..|.|| .   ..||.| ||.     .   ||||  || .. |. ..||. | .
IKLCRKLGQGQFGEVWMGYWNGN---TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCS

Kinase AqueK278.AA RTKL 567-633 35 6.5e-16 38.1 In-house 1-67 (259) Show / Hide
Range on Protein: 567-633
Range on HMM: 1-67/259
Sequence Identity: 35% (24 aa)

ISIAEEIGSGQFGTVFKGVWNSSCGPIDVAIKKLKENFAEEDKVKFLQEGAIMGQFHHPSIIQLHGV
.   .| |.|||. |. .   |   |  |||| ..|  .       | |   . | ||| |||.||.
FILENELGRGQFSRVYQARSCSRMVPTQVAIKIAHEQQSKNQMDAVLYEAVLLHQLHHPHIIQMHGC

Kinase AqueK278.AA FAK 567-635 31 1.9e-15 48.06 In-house 1-94 (285) Show / Hide
Range on Protein: 567-635
Range on HMM: 1-94/285
Sequence Identity: 31% (30 aa)

ISIAEEIGSGQFGTVFKGVWNSSCG-------------------------PIDVAIKKLKENFAEEDKVKFLQEGAIMGQFHHPSIIQLHGVIT
|     || |||| |..||. .  .                          |.||||  |..  .. | ||.||  || || || |..| |...
ITLNRCIGEGQFGDVYQGVYTNHKNGKGKNLAGNGKNSNSDQRNADSRPDKIQVAIKTCKKCCDDDNKEKFMQEAYIMKQFDHPHIVKLIGICE

Kinase AqueK278.AA Fer 567-635 25 2.5e-15 48.79 In-house 1-79 (283) Show / Hide
Range on Protein: 567-635
Range on HMM: 1-79/283
Sequence Identity: 25% (20 aa)

ISIAEEIGSGQFGTVFKG------VWNSSCGP--IDVAIKKLKENFAEED-KVKFLQEGAIMGQ-FHHPSIIQLHGVIT
. . . .|.| ||.|.||          .. .  ..|. ||.|...| .. . .|..|  || . . || .....||..
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCV

Kinase AqueK278.AA UTK 567-633 28 8.1e-15 47.12 In-house 1-78 (296) Show / Hide
Range on Protein: 567-633
Range on HMM: 1-78/296
Sequence Identity: 28% (22 aa)

ISIAEEIGSGQFGTVFKGVWNSSC---GPIDVAIKKLK-ENFAEEDKV---KFLQEGA---IMGQFH-HPSIIQLHGV
. . ...|.|.||.|.|. ..      .  |||.|... . .|. ..    .|. | .   .|.||| ||....| ||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGV

Kinase AqueK278.AA Ack 567-633 35 1e-14 46.09 In-house 1-70 (266) Show / Hide
Range on Protein: 567-633
Range on HMM: 1-70/266
Sequence Identity: 35% (25 aa)

ISIAEEIGSGQFGTVFKGVWNS-SCGPIDVAIKKLKENFAEED--KVKFLQEGAIMGQFHHPSIIQLHGV
|.  |..|.| || | .|.|   .   | ||.| |.      .     ||.| ||| .  ||... |.||
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGV

Kinase AqueK278.AA Frk 567-636 41 7.9e-14 43.98 In-house 1-65 (260) Show / Hide
Range on Protein: 567-636
Range on HMM: 1-65/260
Sequence Identity: 41% (29 aa)

ISIAEEIGSGQFGTVFKGVWNSSCGPIDVAIKKLKENFAEEDKVKFLQEGAIMGQFHHPSIIQLHGVITI
| .  ..|||||| |. | || .   . ||.|.||   .  |   ||.|  || .  || .|||. | |.
IQLIRRLGSGQFGEVWEGLWNNT---TPVAVKTLKPGTM--DPNDFLREAQIMKKLRHPKLIQLYAVCTV

Kinase AqueK278.AA Pkinase 567-633 30 3e-09 33.8 Pfam 1-68 (293) Show / Hide
Range on Protein: 567-633
Range on HMM: 1-68/293
Sequence Identity: 30% (21 aa)

ISIAEEIGSGQFGTVFKGVWNSSCGPIDVAIKKLKENFAEEDKV--KFL-QEGAIMGQFHHPSIIQLHGV
. | . |||| ||.|.|... ...    ||.|..|   ....|   ... .| .||  ..|| |..|...
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDW