Gene AqueK299 (A.queenslandica)

AqueK299

Species: A.queenslandica
Alias: AqueK299
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK299.AA Protein None 204 None Fasta, JSON
AqueK299.kin_dom Protein Kinase Domain None 157 None Fasta, JSON

Protein domain

Protein domains of AqueK299.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK299.AA Pkinase_Tyr 1-138 42 1.1e-75 256.89 Pfam 124-265 (270) Show / Hide 
Range on Protein: 1-138
Range on HMM: 124-265/270
Sequence Identity: 42% (61 aa)

MEYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDL-HDENY-YISNSKMIPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKP-FENYTNQE
||||. |...||||||||.|... ...||.|||..||. .|..| . . . ..||||.|||..........|||||.| .|.|| ..| .| ... .|.|
MEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEE

CLRRV-DSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQ
 .... ..| |.|.|..||  ||..| ||||.|   |||| .
VYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSE
Kinase AqueK299.AA Eph 1-138 47 1.2e-68 229.65 In-house 118-259 (264) Show / Hide 
Range on Protein: 1-138
Range on HMM: 118-259/264
Sequence Identity: 47% (67 aa)

MEYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDLHDEN----YYISNSKMIPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKPFENYTNQ
| |||  ..|||||||||||.  .  ||..|||.|| | |.      | ...  |||.||||||. .....||||||||| || |. | | .|. . .||
MKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQ

ECLRRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQ
. .  .. |.|||||..||......| .||. |  .||.| |
DVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQ
Kinase AqueK299.AA TK 1-138 29 5.3e-67 223.4 In-house 247-481 (486) Show / Hide 
Range on Protein: 1-138
Range on HMM: 247-481/486
Sequence Identity: 29% (69 aa)

MEYLSKK------GFVHRDLAARNILIADHGT-----------CKIADFGMS--------RDL-HDENYYISN------------------------SKM
||||..|      .||||||||||.|......           |||||||.|        ||. .|..|| ..                        . .
MEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGK

IPIKWTAPEALH---------FKRYSSASDVWSYGAVMYEIWSLGHKPFEN-YTN---------QECLRRVDSG--------------FRLPPPPGCP--
.||.|.|||.|          .......|||||.| .|.||...| .|.    .|         || .... .|              .|.|.||.||  
LPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDW

------------RSIYEMMIQCWHPDTGSRPTFVQ
              .|..| ||||.|   |||| |
MRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQ
Kinase AqueK299.AA Src 1-136 46 3.4e-64 216.97 In-house 110-248 (255) Show / Hide 
Range on Protein: 1-136
Range on HMM: 110-248/255
Sequence Identity: 46% (64 aa)

MEYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDLH--DENYYISNSKMIPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKPFENYTNQEC
|.||... ..||||||||.|. ..  ||.||||  | .   |..|  .   ..|||||||||... |..  |||||.|  ..|| . |  | .  ||.| 
MAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEV

LRRVDSGFRLPPPPGCPRSIYE-MMIQCWHPDTGSRPTF
|..|. |.|.| |..|| ..||  | |||| |   ||||
LQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTF
Kinase AqueK299.AA SFK-Src 1-136 48 1.6e-62 183.87 In-house 109-248 (259) Show / Hide 
Range on Protein: 1-136
Range on HMM: 109-248/259
Sequence Identity: 48% (68 aa)

MEYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDLHDENY-YISNSKM-IPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKPFENYTNQEC
| ||  . ||||||||||.|. |  .||..|||||| | ...  |        |||||||||    |.|  |||||.|  |.||  .| .|..  ||.| 
MAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEV

LRRVDS--GFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTF
|..||   | |.| ||.||   |..|..||      ||||
LQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK299.AA UTK 1-138 40 1.7e-62 212.65 In-house 131-291 (296) Show / Hide 
Range on Protein: 1-138
Range on HMM: 131-291/296
Sequence Identity: 40% (66 aa)

MEYLSKKGFVHRDLAARNILIADHG-------TCKIADFG---MSRDLH---------DENYYISN-SKMIPIKWTAPEALHFK-RYSSASDVWSYGAVM
|.||. .|||||||||||.|...|.       .|||||||   |||...         . .|| ..  ...||.|.|||||    |....|||||.| |.
MQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVC

YEIWSLGHKPFENYTNQECLRRVDSG--FRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQ
.|||. | .|.....|.. . .|  |   |.|.|..||...|..| .|||.|   ||.|..
WEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFED
Kinase AqueK299.AA TK-Unique 1-136 40 4.7e-58 198.75 In-house 144-287 (294) Show / Hide 
Range on Protein: 1-136
Range on HMM: 144-287/294
Sequence Identity: 40% (58 aa)

MEYLSK--KGFVHRDLAARNILIADHGTCKIADFGMSRDLHDENYYISN-S-KMIPIKWTAPEALH--FKRY-SSASDVWSYGAVMYEIWSLGHKPFENY
||||..  |..|||||.|||.|......|||.||||.||..... |... | ..|||.| |||.|    . | .. |||||.| .|.|| .||  |. ..
MEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGM

TNQECLRRVDSGFRLPPPPGC-PRSIYEMMIQCWHPDTGSRPTF
 . . ....  |.|.| |..| .. .|. |..||. .  .||.|
PWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSF
Kinase AqueK299.AA SRM 1-136 43 2.9e-57 190.02 In-house 110-245 (253) Show / Hide 
Range on Protein: 1-136
Range on HMM: 110-245/253
Sequence Identity: 43% (59 aa)

MEYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDLHDENYYISNSKMIPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKPFENYTNQECLR
| ||  . ..||||||||.|. |  .||..|||. | . |  |  | .  ||.|||||||.    ||  |||||.|  ..|. . |  |..  || | . 
MCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPGMTNHETFQ

RVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTF
..| |.|.| |  || ... .|..||  |   ||.|
QIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCF
Kinase AqueK299.AA CTKA 1-138 45 8.5e-57 189.32 In-house 144-285 (290) Show / Hide 
Range on Protein: 1-138
Range on HMM: 144-285/290
Sequence Identity: 45% (64 aa)

MEYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDLHDE--NYYISNSKMIPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKPFENYTNQEC
|.||.  ||||||||.||.|.    . |||||| .| |  |   ||.| . ..|. | ||||| | ..|.|||||..| ...|| | | ||.   . || 
MNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEV

LRRVDSG--FRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQ
   . |.   |||.|. ||  .| .|  || .    ||||..
CQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFET
Kinase AqueK299.AA Tec 1-138 46 3.9e-54 186.17 In-house 110-247 (254) Show / Hide 
Range on Protein: 1-138
Range on HMM: 110-247/254
Sequence Identity: 46% (65 aa)

MEYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDLHDENYYISN-SKMIPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKPFENYTNQECL
|.|| ...|.|||||||| |. | .  |..||||.|   |  |  |  .|  |.|| .|| .|. |||| ||||..|  | |..|.|  |.||..| |  
MAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKF-PVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVV

RRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQ
 .|  |.||  |  |. .||. | .|||     |||| |
EHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQ
Kinase AqueK299.AA Fer 1-138 36 2.3e-53 180.12 In-house 124-277 (283) Show / Hide 
Range on Protein: 1-138
Range on HMM: 124-277/283
Sequence Identity: 36% (56 aa)

MEYLSKKGFVHRDLAARNILIADHGT---CKIADFGMSRDLHDENYYIS---NSKMIPIKWTAPEALHFKRYSSASDVWSYGAVMYEIWSLGHKPFEN--
|||| .|. .|||.||||.|. ....   |||.||||||.. |. |  .    ....||.|.|||.. .. ||...||||.| ...|| . | .|...  
MEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQP

----YTNQ--ECLRR-VDSGFRLPPPPGCPRSIYEMMI-QCWHPDTGSRPTFVQ
     ||.  .. .. ...| ..|.|...|  |.. |  |||. |.  |||. .
HGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKE
Kinase AqueK299.AA TyrKc 1-152 22 4.7e-21 77.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-152
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

M---------------------------------------------------------------------------------------------------
                                                                                                    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

-------------EYLSKKGFVHRDLAARNILIADHGTCKIADFGMSRDLHDE-------NYYIS----NSKM-IPIKWTAPEALHFKRYSSASDVWSYG
             |||..|...||||||||.|... .|.||.|||.|||..|.        || .    ..|. .||.|.|||.. .......|||||.|
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFG

AVMYEIWSLGHKPFEN-----YTNQECLRRVDSGFRLPPPPG--------CPRSIYEMMIQCWHPDTGSRPTFVQNPDSNHRPTFKDIL
 .|.|| ..| .| ..      .||| ...|..|.|.|.||         ||  .|..| |||| |  .|||| .          ....
VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---------HECF
Kinase AqueK299.AA Pkinase 1-155 21 2.4e-14 51.8 Pfam 121-293 (293) Show / Hide 
Range on Protein: 1-155
Range on HMM: 121-293/293
Sequence Identity: 21% (41 aa)

MEYLSKKGFVHRDLAARNILIADHGTC----KIADFGMSRDLHDENYYISNSKMIPIKWTAPEALH-FKRYSSASDVWSYGAVMYEIWSLGHKPFENY--
.||. ..|..||||   |||| ..|..    ||.||| .. .   |.   ..    . . ||| .   . |....|.||.| ..||  . |. || .   
LEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCW

----TNQECLRRVDS-GFRLPPPPGCP-------------------RSIYEMMIQCWHPDTGSRPTFVQNPDSNHRPTFKDILDK--L
    . .....|. .  .. . |  |.                   ..  . .  |...|  .|||            ...||    .
HDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT------------AEQILQHPWF
Kinase AqueK299.AA S_TKc 1-148 15 2e-06 -81.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-148
Range on HMM: 1-231/231
Sequence Identity: 15% (39 aa)

M-----------------------------------------------------------------EYLSK-----------------------------
                                                                  ||..                              
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

------------KGFVHRDLAARNILIADHGTCKIADFGMSRDLHDENYYISNSKMIPIKWTAPEALHFKRYSS-ASDVWSYGAVMYEIWSLGHKPFENY
            .|..||||   |||. .  . ||.|||..| |        ..      . ||| |    |.  ..|.|| | ..||  . |  ||.  
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--

TNQECLRRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQNPD----SNHRPTF
. |. ....            ...  ... .|.. |   |||  .        .  | |
QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK299.AA TK 139-155 35 0.000828 7.8 In-house 470-486 (486) Show / Hide 
Range on Protein: 139-155
Range on HMM: 470-486/486
Sequence Identity: 35% (6 aa)

NPDSNHRPTFKDILDKL
..| ..||||......|
HYDPEDRPTFSQLHEQL
Kinase AqueK299.AA Tec 145-157 53 0.006934 6.01 In-house 242-254 (254) Show / Hide 
Range on Protein: 145-157
Range on HMM: 242-254/254
Sequence Identity: 53% (7 aa)

RPTFKDILDKLTE
||||.. |...||
RPTFQQLLRQITE
Kinase AqueK299.AA Pkinase_Tyr 139-155 41 0.00814 10.16 Pfam 254-270 (270) Show / Hide 
Range on Protein: 139-155
Range on HMM: 254-270/270
Sequence Identity: 41% (7 aa)

NPDSNHRPTFKDILDKL
..| ..||||..|. .|
HYDPEDRPTFSEIHEQL
Kinase AqueK299.AA SRM 145-156 66 0.018599 3.84 In-house 242-253 (253) Show / Hide 
Range on Protein: 145-156
Range on HMM: 242-253/253
Sequence Identity: 66% (8 aa)

RPTFKDILDKLT
||.|||   |||
RPCFKDLREKLT
Kinase AqueK299.AA TK-Unique 141-155 33 0.020546 4.28 In-house 280-294 (294) Show / Hide 
Range on Protein: 141-155
Range on HMM: 280-294/294
Sequence Identity: 33% (5 aa)

DSNHRPTFKDILDKL
.  .||.| .|...|
EPEERPSFRQIKHRL
Kinase AqueK299.AA Eph 141-155 53 0.030189 3.19 In-house 250-264 (264) Show / Hide 
Range on Protein: 141-155
Range on HMM: 250-264/264
Sequence Identity: 53% (8 aa)

DSNHRPTFKDILDKL
| ||||.|..|   |
DRNHRPHFQQIVSIL
Kinase AqueK299.AA UTK 145-155 36 0.039971 3.07 In-house 286-296 (296) Show / Hide 
Range on Protein: 145-155
Range on HMM: 286-296/296
Sequence Identity: 36% (4 aa)

RPTFKDILDKL
||.|.|.....
RPDFEDLVQQM
Kinase AqueK299.AA Src 141-155 40 0.049163 2.65 In-house 241-255 (255) Show / Hide 
Range on Protein: 141-155
Range on HMM: 241-255/255
Sequence Identity: 40% (6 aa)

DSNHRPTFKDILDKL
|   ||||. . ..|
DPEQRPTFEYLQWFL
Kinase AqueK299.AA CTKA 143-155 46 0.139588 0.92 In-house 278-290 (290) Show / Hide 
Range on Protein: 143-155
Range on HMM: 278-290/290
Sequence Identity: 46% (6 aa)

NHRPTFKDILDKL
| ||||  ..  |
NQRPTFETLQRML
Kinase AqueK299.AA Fer 145-156 58 0.179548 0.91 In-house 272-283 (283) Show / Hide 
Range on Protein: 145-156
Range on HMM: 272-283/283
Sequence Identity: 58% (7 aa)

RPTFKDILDKLT
|||.|.|  || 
RPTMKEICQKLK