Gene AqueK302 (A.queenslandica)
AqueK302
Species: A.queenslandica
Alias: AqueK302
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK302.AA | Protein | None | 716 | None | Fasta, JSON |
| AqueK302.kin_dom | Protein Kinase Domain | None | 190 | None | Fasta, JSON |
Protein domains of AqueK302.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Pkinase_Tyr | AqueK302.AA | Pkinase_Tyr | 1-204 | 39 | 1.7e-93 | 317.27 | Pfam | 83-270 (270) | Show / Hide |
Range on Protein: 1-204 Range on HMM: 83-270/270 Sequence Identity: 39% (81 aa) MIVLELIPHGDMRHYLHTLQPQYVLSADYVINIVYNRPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHD .||.|. ||||...||.. | . . ||..|.|||.|||||. |...||||||||.| |. . .||.|||..||... YIVMEYMPHGDLLDYLRKHR-------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYN ENYY-VSTTAKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLGHKP-FENCTNQECLRRV-DSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTF . || .... ..||||.|||..... ....||||||| .|.|| ..| .| .....|.| .... ..| |.|.|..|| ||..| ||||.| |||| DDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTF VQLVSRL .....| SEIHEQL |
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| Kinase | AqueK302.AA | TK | 1-204 | 25 | 2.5e-84 | 282.49 | In-house | 131-486 (486) | Show / Hide |
Range on Protein: 1-204
Range on HMM: 131-486/486
Sequence Identity: 25% (91 aa)
MIVLELIPHGD----MRHYLHTLQPQYVLSADYVI-------------------------NIVYNRPGELVAS---------------------------
|||.|. |||| |.||.. | ..| | . ... . .
MIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCK
--TVPGLLLSFCRQIASGMEYLSKK------GFVHRDLAARNILMTDHGM-----------CKIADFGMS--------RDLHDENYYVSTT---------
. || .|.|||.|||||..| .||||||||||.| .... |||||||.| ||.... .|....
HQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMW
---------------AKRIPIKWTAPEALH---------FKHYSSASDVWSFGAVMYEIWSLGHKPFEN-CTN---------QECLRRVDSG--------
..||.|.|||.| .......||||||| .|.||...| .|. .| || .... .|
PFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGL
------FRLPPPPGCP--------------RSIYEMMIQCWHPDTGSRPTFVQLVSRL
.|.|.||.|| .|..| ||||.| |||| ||...|
NEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | AqueK302.AA | Eph | 57-204 | 48 | 4.7e-76 | 254.95 | In-house | 114-264 (264) | Show / Hide |
Range on Protein: 57-204 Range on HMM: 114-264/264 Sequence Identity: 48% (73 aa) IASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDEN----YYVSTTAKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLGHKPFE ||||| ||| ..||||||||||| . .||..|||.|| | |. | .. .|||.||||||. .....|||||||.| || |. | | .|. IASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW NCTNQECLRRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQLVSRL . .||. . .. |.|||||..||......| .||. | .||.| |.|| | DMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL |
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| Kinase | AqueK302.AA | UTK | 1-204 | 36 | 3.9e-74 | 252.61 | In-house | 86-296 (296) | Show / Hide |
Range on Protein: 1-204 Range on HMM: 86-296/296 Sequence Identity: 36% (83 aa) MIVLELIPHGDMRHYLHTLQPQYVLSADYVINIVYNRPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHG-------MCKIADFG |||.|. . ||.|.|| . |. . .. .|.....||.||.||. .|||||||||||.| ..|. ||||||| MIVTEYMENGDLRSYLRRHRPTPP---------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFG ---MSRDLH---------DENYYVSTTAKRIPIKWTAPEALHFK-HYSSASDVWSFGAVMYEIWSLGHKPFENCTNQECLRRVDSG--FRLPPPPGCPRS |||... . .|| .. ..|.||.|.||||| .....||||||| |..|||. | .|... .|.. . .| | |.|.|..||.. RGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHP IYEMMIQCWHPDTGSRPTFVQLVSRL .|..| .|||.| ||.|..||... VYRLMHRCWHYDPQERPDFEDLVQQM |
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| Kinase | AqueK302.AA | TK-Unique | 1-204 | 38 | 5.2e-74 | 252.2 | In-house | 81-294 (294) | Show / Hide |
Range on Protein: 1-204 Range on HMM: 81-294/294 Sequence Identity: 38% (82 aa) MIVLELIPHGDMRHYLHTLQPQYVLSADYVINIV----YNRPGELVASTVPGLLLSFCRQIASGMEYLSK--KGFVHRDLAARNILMTDHGMCKIADFGM ||..| .| |. .|||.| .|. . . |. |. ..... . .. |..|..|. |||.|||||.. |..|||||.|||.|.|....|||.|||| MIIMEYCPCGNLQHYLRTCRPAMRQHQTYG-NLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGM SRDLHDENYYVST-TAKRIPIKWTAPEALH--FKHY-SSASDVWSFGAVMYEIWSLGHKPFENCTNQECLRRVDSGFRLPPPPGC-PRSIYEMMIQCWHP .||..... |... . .||||.| |||.| ..| .. ||||||| .|.|| .|| |. . . . .... |.|.| |..| .. .|. |..||. ARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQW DTGSRPTFVQLVSRL . .||.| |...|| EPEERPSFRQIKHRL |
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| Kinase | AqueK302.AA | Src | 50-204 | 44 | 9.4e-72 | 243.05 | In-house | 99-255 (255) | Show / Hide |
Range on Protein: 50-204 Range on HMM: 99-255/255 Sequence Identity: 44% (70 aa) LLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLH-DENYYVSTTAKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLGH |... |.|.||.||... ..||||||||.| .. .||.|||| | . |.. |.. . ..|||||||||... ... ||||||| ..|| . | LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGR KPFENCTNQECLRRVDSGFRLPPPPGCPRSIYE-MMIQCWHPDTGSRPTFVQLVSRL | . ||.| |..|. |.|.| |..|| ..|| | |||| | |||| | . | VPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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| Kinase | AqueK302.AA | SRM | 50-205 | 44 | 4e-66 | 220.13 | In-house | 99-253 (253) | Show / Hide |
Range on Protein: 50-205 Range on HMM: 99-253/253 Sequence Identity: 44% (69 aa) LLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDENYYVSTTAKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLGHK || | |.| || || . ..||||||||.| .| .||..|||. | . | | | . ||.|||||||. ||| ||||||| ..|. . | LLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHN-IPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQC PFENCTNQECLRRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQLVSRLS |.. || | . ..| |.|.| | || ... .|..|| | ||.| .| .|. PYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT |
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| Kinase | AqueK302.AA | CTKA | 52-204 | 44 | 1.2e-64 | 216.16 | In-house | 135-290 (290) | Show / Hide |
Range on Protein: 52-204 Range on HMM: 135-290/290 Sequence Identity: 44% (70 aa) SFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDE-NYYVSTTAKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLGHKP . .||| ||.||. ||||||||.||.|. |||||| .| | | ||.. ..|. | ||||| | .|.|||||.|| ...|| | | || YMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKP FENCTNQECLRRVDSG--FRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQLVSRL . . || . |. |||.|. || .| .| || . ||||..| | WRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML |
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| Kinase | AqueK302.AA | Syk | 56-198 | 47 | 5.8e-64 | 218.8 | In-house | 114-257 (257) | Show / Hide |
Range on Protein: 56-198 Range on HMM: 114-257/257 Sequence Identity: 47% (68 aa) QIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDL-HDENYYVSTTAKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLGHKPFENC |.|.|| || | ||||||||||.| .. . || |||||. | |..||..||. . |.|| ||| . |..||||||| | | |.| || QVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEM TNQECLRRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFV ..|| . ...| |.. |.|||. .|. | .|| . ||||| KGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV |
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| Kinase | AqueK302.AA | Tec | 48-206 | 44 | 1.3e-63 | 217.67 | In-house | 97-254 (254) | Show / Hide |
Range on Protein: 48-206 Range on HMM: 97-254/254 Sequence Identity: 44% (70 aa) GLLLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDENYYVSTTAKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLG ..||. | .. ||.|| ...|.|||||||| | | . |..||||.| | | |. .| |.|| .|| .|. ||| ||||.|| | |..|.| AILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTK-FPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCG HKPFENCTNQECLRRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQLVSRLSL |.|| .| | .| |.|| | |. .||. | .||| |||| || . . KMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE |
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| Kinase | AqueK302.AA | Fer | 53-205 | 37 | 3.8e-63 | 213.9 | In-house | 116-283 (283) | Show / Hide |
Range on Protein: 53-205 Range on HMM: 116-283/283 Sequence Identity: 37% (63 aa) FCRQIASGMEYLSKKGFVHRDLAARNILMTDHGM---CKIADFGMSRDLHDENYYVSTT--AKRIPIKWTAPEALHFKHYSSASDVWSFGAVMYEIWSLG .| |.|.||||| .|. .|||.||||.|..... |||.||||||.. |. | . |...||.|.|||.. .. ||...|||||| ...|| . | MCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNG HKPFEN------CTNQ--ECLRR-VDSGFRLPPPPGCPRSIYEMMI-QCWHPDTGSRPTFVQLVSRLS .|... .||. .. .. ...| ..|.|...| |.. | |||. |. |||. ... .| AEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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| Kinase | AqueK302.AA | TyrKc | 1-204 | 27 | 2.5e-57 | 197.69 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1-204
Range on HMM: 1-280/280
Sequence Identity: 27% (84 aa)
M--------------------------------------------------------------------------IVLELIPHGDMRHYLHTLQPQYVLS
||.|. |||| ..||. .|.
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK----
ADYVINIVYNRPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDE-------NYYVSTT--AKR--IPIK
. ||||| |||.|||||..|...||||||||.| .. . .||.|||.|||..|. ||.... .. .||.
------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR
WTAPEALHFKHYSSASDVWSFGAVMYEIWSLGHKPFEN-----CTNQECLRRVDSGFRLPPPPG--------CPRSIYEMMIQCWHPDTGSRPTFVQLVS
|.|||.. .. ....||||||| .|.|| ..| .| .. ..||| ...|..|.|.|.|| || .|..| |||| | .|||| ....
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE
RL
..
CF
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| Kinase | AqueK302.AA | Pkinase | 52-204 | 22 | 1.4e-21 | 77.39 | Pfam | 112-293 (293) | Show / Hide |
Range on Protein: 52-204 Range on HMM: 112-293/293 Sequence Identity: 22% (42 aa) SFCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMC----KIADFGMSRDLHDENYYVSTTAKRIPIKWTAPEALH-FKHYSSASDVWSFGAVMYEIWSL ....||..|.||. ..|..|||| |||. ..| . ||.||| .. . . .. .| . . ||| . ..|....|.||.| ..|| . FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC- GHKPFENC------TNQECLRRVDS-GFRLPPPPGCP-------------------RSIYEMMIQCWHPDTGSRPTFVQLVSR--L |. || .. . .....|. . .. . | |. .. . . |...| .|||. |.. . GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | AqueK302.AA | S_TKc | 1-206 | 17 | 3.3e-12 | 2.03 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1-206 Range on HMM: 1-231/231 Sequence Identity: 17% (46 aa) MIVLELIPHGDM---------------------------RHYLHTLQPQYVLSADYVIN-IVYNRPGELVAS--------------------TVPGLLLS .|..| .| . . |. . .. .|. . |.. . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARF FCRQIASGMEYLSKKGFVHRDLAARNILMTDHGMCKIADFGMSRDLHDENYYVSTTAKRIPIKWTAPEALHFKHYSS-ASDVWSFGAVMYEIWSLGHKPF ...||....||. ..|..|||| |||... ||.|||..| | | . ||| | .|. ..|.||.| ..|| . | || YMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPF ENCTNQECLRRVDSGFRLPPPPGCPRSIYEMMIQCWHPDTGSRPTFVQLVS-------RLSL . . |. .... ... ... .|.. | ||| .. . P--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | AqueK302.AA | Fer | 1-16 | 43 | 0.124435 | 1.46 | In-house | 85-100 (283) | Show / Hide |
Range on Protein: 1-16 Range on HMM: 85-100/283 Sequence Identity: 43% (7 aa) MIVLELIPHGDMRHYL |||.|....|. . || MIVMEFCNGGSLDSYL |
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