Gene AqueK310 (A.queenslandica)

AqueK310

Species: A.queenslandica
Alias: AqueK310
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK310.AA Protein None 1045 None Fasta, JSON
AqueK310.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of AqueK310.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
EPH_lbd AqueK310.AA EPH_lbd 49-238 17 3.1e-07 -7.87 SMART 1-184 (184) Show / Hide 
Range on Protein: 49-238
Range on HMM: 1-184/184
Sequence Identity: 17% (38 aa)

EKILLDSQNYRSVFLVGAEGENRTWLTIDYDGGGVGRTGAAGFVDS--WYEGNQGVQC---LHRINVCATL-IPGGTSSFQSNWLITQYINISEPGISQL
| .|.|.  . .            |.| ..              ..  | |  .        .   ||    |.   .. |.|||.|..|.  .   .. 
EVVLMDTKTETGELG---------WTTYPP--------------HGGTWEEVSGMDEHHNPIRTYQVCNVMEIN--EPN-QNNWLRTHWIYRRG--AQRI

RINVTFSSNLVCLNQQCPQ---QQTFEVQTFETNEPDEMDRGNIS----YYSYAGVRLIHTAVE--------GATTESESFA-VSSSGLYLAIWDQGSCT
 . . |. .        .    ..|| ... |... .. .  ..     | .  ... ..   .          .||  ||  .|  |.|||  ||| | 
YVELKFTMRDCNSMPGVAGVSCKETFNLYYYESDNDHATAHTPFWMENPYIKIDTIAADESFTQRDFGDRVMKMNTEVRSFGPLSKKGFYLAFQDQGACM

VINRIVVFYNVC
 . .  |||  |
ALVSVRVFYKKC
GCC2_GCC3 AqueK310.AA GCC2_GCC3 302-342 40 0.000227 17.18 Pfam 4-45 (49) Show / Hide 
Range on Protein: 302-342
Range on HMM: 4-45/49
Sequence Identity: 40% (17 aa)

YEANDTVCEACPTGTYKKSPGDTSCDDCPDN-SDSLNTGSTS
| ..   ||.|| |||. . | .||  ||.. .  . .||||
YNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTS
FN3 AqueK310.AA FN3 365-446 23 3.7e-11 44.32 SMART 1-69 (69) Show / Hide 
Range on Protein: 365-446
Range on HMM: 1-69/69
Sequence Identity: 23% (23 aa)

PGPPVS---LRNTSFNST------SISIAWDPPVSNGSRSDINYLVSITDQSNGNSIVPHTTNTTIYKRGGLTPL----TTYTITVTSRNG--VSDQ
||||     || |. .||      |... |.||        ..|                      |.  ||.|     |.|...|. .||  .   
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
FN3 AqueK310.AA FN3 467-553 16 4.3e-05 24.17 SMART 1-69 (69) Show / Hide 
Range on Protein: 467-553
Range on HMM: 1-69/69
Sequence Identity: 16% (17 aa)

PTSPQS---LSLQRPTPSGQ----STILGWSEPQNSYGTVIRYNIFVSEFNDTDTATVRGTVNGTTFRYDLSQLDLTSG-----SYFVWVQAVTI--HGE
| .|.    |..   |...     |  | |..|      ...|                               .|. |      | ..|.||.   .||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR--------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE

S
.
G
Pkinase_Tyr AqueK310.AA Pkinase_Tyr 681-933 43 6.2e-136 461.0 Pfam 1-270 (270) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-270/270
Sequence Identity: 43% (118 aa)

IANLEEIGVGEFGLVYKGVWT----LKNIPVAVKTLRGGATDEQ--RSNFLFEASVMGQF-HHDNVVVLYGVIS-RIDP--VMIVMEYLQNGSLDRYLQK
|  ....| |.|| ||||.|.     ..||||||.|. ||..||  |  |. ||..| |. ||.|.| ||||.. . .|  ..||||| ..|.|. ||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---LDKISHERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREM-VENEY-DVQKGGRIPVRWTAPEAISHRSFTTASDVWSY
.    .......| .|.. .|||| ||.|....||||||||.||... ..|..|||||| .  . .|  ...||..|..|.|||.|... |||.|||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVLLWETFSFGETP-YDGWDNATIFQRL-ENGERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVECF
|||.|| |..||.| | |..|. ..... |.|.|. .|..|||..|..|. ||. . ..||||. |.|..
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK310.AA TyrKc 681-933 40 1.9e-133 450.57 SMART 1-280 (280) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-280/280
Sequence Identity: 40% (115 aa)

IANLEEIGVGEFGLVYKGVWTLKNIPVAVKTLRGGATDEQRSNFLFEASVMGQF--HHDNVVVLYGVISRI-------DPVMIVMEYLQNGSLDRYLQKN
|  ....| |.|| ||||.|.   |.||||.|. .|    |  |. ||..| ..  ||.|.| ||||..         .|.||||||  .|.|. ||.|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

LDKISHERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREMVEN-------EYDVQK---GGR--IPVRWTAPEAISHRSFTTA
 .|.... | .... .|.|| ||.| ...||||||||.||... |.|..||||.|.  .        .| ..|   ||.  .|.||.|||.| .. |||.
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

SDVWSYGVLLWETFSFGETPYDG-----WDNATIFQRLENGERLHPPRG--------CPDDLYKIMQACWNIERSERPTFENIVECF
|||||.||..|| |..|..|| |      .|. .......|.|. .|          |||..|.||. ||. . ..||||..|.|||
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK310.AA Eph 681-933 48 5e-126 425.0 In-house 1-264 (264) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-264/264
Sequence Identity: 48% (129 aa)

IANLEEIGVGEFGLVYKGVWTLK----NI---PVAVKTLRGGATDEQRSNFLFEASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLD
|   . || |||| |..|   |.     .   |||.|||. |.|. || .|| |||.|||| | |.. | ||...  ||||| ||  ||||| .| .. .
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

KISHERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAR----EM-VENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVL
...  .|  | .|.| ||||||. ..||||||||||||  .  |||.|||| |    .  || .|  . ||.||.||||||||..| ||.||||||||..
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIV

LWETFSFGETPYDGWDNATIFQRLENGERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVECF
.||  |.|| ||  . |  . .  | | || ||..||  |...|. ||  .|..||.|..||  .
MWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase AqueK310.AA TK 681-933 24 1.3e-113 382.43 In-house 1-486 (486) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-486/486
Sequence Identity: 24% (118 aa)

IANLEEIGVGEFG---LVYKGVWTLKN-------------------------IPVAVKTLRGGATDEQRS-------------NFLFEASVMGQFH----
|  ....| |.||    |||| |  .|                         .|||||.|. |....|.              .|| ||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HDNVVVLYGVISRI------------DPVMIVMEYLQNGS----LDRYLQKNLDK--------------------------------------------
 |.|.| ||||...              |.|||||| ..|.    |. ||.|. .|                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------ISHERLSKMSYGVAKGMKYLSSI------GFVHRDLAARNILVANDET-----------CKVADFG---
                               .. ..|  |.. .|.|| ||.|       .||||||||||.||... .           ||.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAREM-VENEYDVQK------------------------GGRIPVRWTAPEAISHRS---------FTTASDVWSYGVLLWETFSFG-ETPYDGW
     |||..  . .| ...                        ||..|.||.|||.. .|          |||.|||||.|||.|| |..| |..| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DN---------ATIFQRLENG--------------ERLHPPRGCP--------------DDLYKIMQACWNIERSERPTFENIVECF
.|         . ....|..|               |. .| .||              ...| .|| ||. . ..||||. ..|..
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK310.AA Src 681-933 43 4.8e-107 361.94 In-house 1-255 (255) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-255/255
Sequence Identity: 43% (112 aa)

IANLEEIGVGEFGLVYKGVWTLKNIPVAVKTLRGGATDEQRSNFLFEASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQ--KNLDKISHE
|  ....| | || |..|.|  .|..||||||. |    .   || || .| .. |...| || | |. .|. || || ..|||  ||.  .   ... .
IKLCRKLGQGQFGEVWMGYW-NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLP

RLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREMV--ENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFG
.|  |.  ||.||.||.|  ..||||||||.|| ..  |||||||||| .   ..||  ..| ..|..|||||||....||. |||||.|.||.| ...|
QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYG

ETPYDGWDNATIFQRLENGERLHPPRGCPDDLYK-IMQACWNIERSERPTFENIVECF
 .|| |..|.  .|..|.| |.  |..||| ||. ||. ||. .  .||||| . . .
RVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK310.AA UTK 681-933 36 4.5e-101 342.1 In-house 1-296 (296) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-296/296
Sequence Identity: 36% (108 aa)

IANLEEIGVGEFGLVYKGVWT-----LKNIPVAVKTLRGGATDEQRSN----FLFEAS---VMGQFH-HDNVVVLYGVISRIDPVMIVMEYLQNGSLDRY
.. ....| |.|| |.|. .|      .   ||||... .|...| .     |. ||    .|.||| | ||. |.|| ..  | |||.|| .||.|. |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LQKNLDKIS-------HERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVAND-------ETCKVADFG---LAREMV---------ENEYDVQKG-GR
|... ..          ... .|.. .| || ||.| |||||||||||.||. .       ..||.||||   ..|..          | .|  . . .|
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

IPVRWTAPEAISHR-SFTTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENG--ERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVECF
.|.||.||||. |.  |||.|||||.||..||....| .|| |. |. ......||   |. .|..||...|..|..||. . .|||.|| .|. .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK310.AA SFK-Src 681-937 40 1.5e-97 289.69 In-house 1-259 (259) Show / Hide 
Range on Protein: 681-937
Range on HMM: 1-259/259
Sequence Identity: 40% (107 aa)

IANLEEIGVGEFGLVYKGVWTLKNIPVAVKTLRGGATDEQRSNFLFEASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQK-NLDKISHER
|.  .  | | || |.||.|  .   ||||||. ||. ..   || || || .  |.| . || |     |. |. | ...|||  ||.  .        
IRLEKKLGSGQFGDVWKGRWN-NTTEVAVKTLKPGAMSAE--EFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQ

LSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREMV-ENE-YDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFSFGE
|  |   || || ||    ||||||||||.|| .  .|||.|||..| .  ..| |  ..| . |..|||||| .   | . |||||.|.|. |   .| 
LVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGR

TPYDGWDNATIFQRLEN--GERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVECFEVIL
 ||.|  |. . |...   |.|.  | .||| .|||| .||  | ..|||||.     |   
IPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK310.AA TK-Unique 681-933 35 6e-94 318.41 In-house 1-294 (294) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-294/294
Sequence Identity: 35% (103 aa)

IANLEEIGVGEFGLVYKGVWTLKN------IPVAVKTLRGGATDEQRSNFLFEASVMGQFH-HDNVVVLYGVISRID-PVMIVMEYLQNGSLDRYLQKNL
. ....|| |.|| |..|  . ..      . ||||.|. .|||.....|| |...| .   | |.| ..|.  . | |.||.|||...|.|. ||... 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

DK-------------------------ISHERLSKMSYGVAKGMKYLSS--IGFVHRDLAARNILVANDETCKVADFGLAR-EMVENEYDVQKG-GRIPV
..                         || ..|    ...|.||.||.|   ..|||||.|||.|...| .||..|||.|| .. ...|. ... ||||.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWTAPEAIS--HRSF-TTASDVWSYGVLLWETFSFGETPYDGWDNATIFQRLENGERLHPPRGC-PDDLYKIMQACWNIERSERPTFENIVECF
|| |||...  |. . || |||||.|||.|| |..|..|| | ... | .....| |.  | .| ....|..|. ||. |..|||.|. |.  .
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK310.AA Fer 681-934 34 2.6e-93 316.3 In-house 1-283 (283) Show / Hide 
Range on Protein: 681-934
Range on HMM: 1-283/283
Sequence Identity: 34% (98 aa)

IANLEEIGVGEFGLVYKG--VWTLKN--------IPVAVKTLRGG-ATDEQRSNFLFEASVMGQ-FHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYL
.   . .| | || ||||  . ..|.        ..|.||....  ||.||.  |. || .| . . |.||| .|||..   |.|||||.  .|||| ||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

QKNLDK-ISHERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDET---CKVADFGLAREMVENEYDVQKG---GRIPVRWTAPEAISHRSFTTASD
.|| .| .|   . .|.|..|.||.|| | . .|||.||||.|. .|..   ||..|||..|.  ...|| ...    ..|.||.|||... . .....|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSYGVLLWETFSFGETPYDG---------WDNATIFQRLENGERLHPPRGCPDDLYKIMQ-ACWNIERSERPTFENIVECFE
|||.||..|| |. |..|| |         ... .. .  ..| .. .| ..|.....||   ||. . ..|||.  |.....
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK310.AA RTKC 681-933 41 5.9e-93 307.13 In-house 1-261 (261) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-261/261
Sequence Identity: 41% (109 aa)

IANLEEIGVGEFGLVYKGVWTLKN-IP---VAVKTLRGGATDEQRSNFLFEASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLDKIS
.  |.| | | ||.|||.       .|   ||.| |.  | |  |.  | || || || | ||| | ||..   |. .|.|.. .|||  || .|  ...
LTLLDELGRGAFGIVYKALLEEPGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMNNP-DCT

HERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREM-----VENEYDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWE
 .     .| .| ||    | ||.|||.||||.|.. | ||||||||||||       .  |    .| .|||||||||   | |. .||||. |.|. |
EHQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVADFGLARESPCNDDSHEAYYRSRSGNLPVRWTAPEALDDRKFSEKSDVWAFGILMYE

TFSFGETPYDGWDNATIFQRLENGERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVECF
 .  .| ||||| |  .     .| || .| .|....|..|..||   ...||||. .|. .
IYTKAEMPYDGWSNQRVWVEVCAGYRLPCPEDCHKEVYDMMMDCWMHTPHDRPTFSEVVHWL
Kinase AqueK310.AA Frk 681-937 42 3.6e-89 302.54 In-house 1-260 (260) Show / Hide 
Range on Protein: 681-937
Range on HMM: 1-260/260
Sequence Identity: 42% (111 aa)

IANLEEIGVGEFGLVYKGVWTLKNIPVAVKTLRGGATDEQRSNFLFEASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQ---KNLDKISH
|  . ..| | || |. | |   ..|||||||. |. | .  .|| || .| .  |  .. || |  . .|..|. | ...|||  |||   ..  ..  
IQLIRRLGSGQFGEVWEGLWN-NTTPVAVKTLKPGTMDPN--DFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQM

ERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAR-EMVENE--YDVQKGGRIPVRWTAPEAISHRSFTTASDVWSYGVLLWETFS
. |  |.  || || || |  ..||||||||.|| ..  ||.|||||||  |..||  |. . | |.|..||||||.   .||. |||||.|.|| |   
QQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIIT

FGETPYDGWDNATIFQRLENGERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVECFEVIL
.|  || |  || . | ...| |.  | .||  ||.||. ||. .  .||||| .   .|  .
YGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK310.AA Ack 681-933 39 4.5e-86 290.33 In-house 1-266 (266) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-266/266
Sequence Identity: 39% (105 aa)

IANLEEIGVGEFGLVYKGVWTL---KNIPVAVKTLRGG--ATDEQRSNFLFEASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQNGSLDRYLQKNLD--
|  .|..| |.|| | .|.||.   | |.|||| || .    ..  . || |...| .  | ..| ||||    . .| |.|    |||   | | .   
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRKHCRTA

KISHERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDE-TCKVADFGLAREMVENE--YDVQKGG--RIPVRWTAPEAISHRSFTTASDVWSYGVL
. .  .|.  .  .|.|| || . ...||||||||||.. |. . |..|||| |   .||  |  .      .|  | |||.. || |. |||||..|| 
FFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVT

LWETFSFGETPYDGWDNATIFQRLE-NGERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVECF
||| ||.|| |. |   . | |... .||||. |  || |.|..|  ||  .  .|||| .|.. .
LWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase AqueK310.AA Pkinase 681-933 23 3.9e-49 174.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 681-933
Range on HMM: 1-293/293
Sequence Identity: 23% (69 aa)

IANLEEIGVGEFGLVYKGVWTLKNIPVAVKTLRGGATDE-QRSNFLF--EASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQNG----SLDRYLQ-KNL
.  .. || | || |||...   .. ||||...   ... .. . .   |...|  ..|.|.| ||..  . | . .||||...|    .| .|.. .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DKI--SHERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETC----KVADFGLAREMVENEYDVQKGGRIPVRWTAPEAIS-HRSFTTASDVWSY
 ..  | . . .. | ...|..|. | |..||||   |||. |. ..    |..|||||. . .  .   ..     .. ||| |  ..  ....|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLWETFSFGETPYDGW----DNATIFQRLENGERLHPPRGCP-----------------------DDLYKIMQACWNIERSERPTFENIVEC--F
|..|.| .. |..|..|     . ..  |....  .  ... .|                       ... ...  |..   ..|||.| |..   |
GCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK310.AA S_TKc 681-936 23 2e-44 154.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 681-936
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

IANLEEIGVGEFGLVYKGVWTLKNIPVAVKTLRGGATDEQRSNFLFEASVMGQFHHDNVVVLYGVISRIDPVMIVMEYLQN--GSLDRYLQKNLDK----
   |..|| | || |||....  .  ||.| ..         ... | ... . ||.|.| ||.|.   | . .||||. .  |.| .|..|.  .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-ISHERLSKMSYGVAKGMKYLSSIGFVHRDLAARNILVANDETCKVADFGLAREMVENEYDVQKGGRIPVRWTAPEAISHRSFTT-ASDVWSYGVLLWET
 ..  .  .. | ......|. | |..||||   |||. .  . |..||||||..        .       . ||| .   .... ..|.|| |..|.| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

FSFGETPYDGWDNATIFQRLENGERLHPPRGCPDDLYKIMQACWNIERSERPTFENIVE------CFEVI
.. |..|..  . ...|...            ....  ... |.. . ..|||   . .      | . .
LC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
SAM_1 AqueK310.AA SAM_1 970-1033 37 1.3e-15 58.27 Pfam 1-66 (66) Show / Hide 
Range on Protein: 970-1033
Range on HMM: 1-66/66
Sequence Identity: 37% (25 aa)

NNKAADSIDELLGSIGMTRYIDIFHAKGLYNVADCFGLSEDDLQR-MGVTLSGHQYKIVKNI-HLK
 ... ....| | |||| .||| |...|. .. ..  ....||.. ||||| ||. ||.. | .||
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHRKKIMYSIQMLK
Sam7 AqueK310.AA sam7 972-1034 28 2.1e-13 45.53 In-house 1-70 (70) Show / Hide 
Range on Protein: 972-1034
Range on HMM: 1-70/70
Sequence Identity: 28% (20 aa)

KAADSIDELLGSIGM---TRYIDIFHAKGL----YNVADCFGLSEDDLQRMGVTLSGHQYKIVKNIHLKE
   ... | | .|||    .|.| |.. |      . ..   ..|.||..||.|. ||. || . |.   
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM_2 AqueK310.AA SAM_2 969-1034 30 8.1e-08 29.68 Pfam 1-71 (71) Show / Hide 
Range on Protein: 969-1034
Range on HMM: 1-71/71
Sequence Identity: 30% (22 aa)

GNNKAADSIDELLGSIGM-TRYIDIFHAKGLYNVADC-FGLSEDDL--Q-RMGVTLSGHQYKIVKNIHLKE
  ....... | | ||||  .| |.| ..|.    .   ....|||  . |||.|. ||. || . |   .
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM AqueK310.AA SAM 969-1036 30 1.1e-07 32.81 SMART 1-67 (67) Show / Hide 
Range on Protein: 969-1036
Range on HMM: 1-67/67
Sequence Identity: 30% (21 aa)

GNNKAADSIDELLGSIGMTRYIDIFHAKGLYNVADCFGLSEDDLQRMGVTLSGHQYKIVKNIHLKEEE
      ... . | |||| .|.|.| . |.   .    .|..||..||.|. ||. || | |.   ..
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ