Gene AqueK312 (A.queenslandica)

AqueK312

Species: A.queenslandica
Alias: AqueK312
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK312.AA Protein None 776 None Fasta, JSON
AqueK312.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of AqueK312.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Sushi AqueK312.AA Sushi 170-223 29 1.1e-14 55.09 Pfam 1-65 (65) Show / Hide 
Range on Protein: 170-223
Range on HMM: 1-65/65
Sequence Identity: 29% (20 aa)

CG-QPSP--PANG-SVTY-------GSTQYGSVITYACYSGYTLNGS--LNNTCSSAGSWTAPTPT-C
|. .|..  . .| ....       . .|.||...| | .||...|.     ||   |.|| | || |
CPFDPPDPNIPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
CCP AqueK312.AA CCP 170-223 30 1.2e-14 55.87 SMART 1-79 (79) Show / Hide 
Range on Protein: 170-223
Range on HMM: 1-79/79
Sequence Identity: 30% (25 aa)

CGQPS---PPANGSVTYGS----------TQYGSVITYACYSGYTLNG-----------SLNNTCSSAGSWTAPT----PTC
|. |    .| ||.||...          . ||...|| | .||||.|           |   || .   |. |.    |||
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
CCP AqueK312.AA CCP 229-287 21 2.7e-14 54.71 SMART 1-79 (79) Show / Hide 
Range on Protein: 229-287
Range on HMM: 1-79/79
Sequence Identity: 21% (18 aa)

CPNIT----INNGSMRANN----SMGRGPFYTGTIVLFTCDVGFRLSG-----------SPRLVCRPDATWDNNT----PTC
||       . ||...  |    |   .....|. | ..|. |..|.|           |....| ..  |.. .    |||
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK312.AA Sushi 229-287 20 3.5e-12 46.14 Pfam 1-65 (65) Show / Hide 
Range on Protein: 229-287
Range on HMM: 1-65/65
Sequence Identity: 20% (14 aa)

CP-NITINNGSMRA-NNSMGR-----GPFYTGTIVLFTCDVGFRLSGS--PRLVCRPDATWDNNTPT-C
||   . .|  ... . . ..     . .  |. | ..|| |....|.  ....|  ...|..  || |
CPFDPPDPN-IPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
Pkinase_Tyr AqueK312.AA Pkinase_Tyr 511-766 40 1.9e-123 418.75 Pfam 1-270 (270) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-270/270
Sequence Identity: 40% (111 aa)

IELKDYLGSGQFGFVHKGIWK------GSLVAVKSLRNETTDID--RVKFLQEAAIMGQF-SHSNIVKLYGLVNEGDDN--IMLVVELMPAGDLQKYLPS
|..   ||.|.|| |.||.||      .  ||||.|.. ... .  | .|..||.|| |. .| |||.||| . . ..   |..|.|.|| ||| .|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

LRNNQSKEGLAESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVELEGYY-VAQRGTMIPIKWTAPEALKFRKYSSASDVWS
 |... .  . . || .| .|..|| ||. ....||||||||.|.| .|..||.|||..||.. ..|| ... |...||||.|||.....|....|||||
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YGCVLYEIWSLGLKP-FEHSHNKE-ANKL-DKGYRMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISRFL
.| ...|| ..| .| ..   | |  ... ..|||||.| .||  .|.|| .|||..|..||.| || ..|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK312.AA TyrKc 511-766 37 5.9e-114 385.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-280/280
Sequence Identity: 37% (108 aa)

IELKDYLGSGQFGFVHKGIWKGSLVAVKSLRNETTDIDRVKFLQEAAIMGQF--SHSNIVKLYGLVNEG------DDNIMLVVELMPAGDLQKYLPSLRN
|.|.. ||.|.|| |.||.||   ||||.|....    |  |..|| || ..  .| |||.||| . ..      .. .|.|.|.|| |||..|| . |.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

NQSKEGLAESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVELE-------GYYVAQR--GTM--IPIKWTAPEALKFRKYS
.       . || .|  |..|| ||......||||||||.|... ...||.|||.|||.. .        ||...   |.   .||.|.|||.....|..
K----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

SASDVWSYGCVLYEIWSLGLKPFEH-----SHNKEA-NKLDKGYRMPPPSG--------CPYLMYKLMILCWHPEPSQRPSFPEISRFL
..|||||.| ...|| ..| .| .        |.|. .....|||||.|          ||  ||..|  ||| .|..||.| || ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK312.AA TK 511-766 23 7.2e-108 362.81 In-house 1-486 (486) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-486/486
Sequence Identity: 23% (113 aa)

IELKDYLGSGQFG---FVHKGIWKG---------------------------SLVAVKSLRNETTDIDRV-------------KFLQEAAIMGQFS----
|.| . ||.||||    |.||.|.|                             |||| |. .... ..              .||.||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HSNIVKLYGLVNEGDDN-----------IMLVVELMPAGD----LQKYLPSLRNNQSKE----------------------------------------
 | |||.||| . .|. .           .|.|.|.|| ||    |..|| . |.. ..|                                        
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------GLAESLLTYCKEICSGMLYLSKR------GFVHRDLAARNILLTATNQ-----------CKIADFGMS-
                                  . || .|  |..|| ||...      .||||||||||.|..  |.           |||||||.| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RDVELEGYYVAQR------------------------GTMIPIKWTAPEALK---------FRKYSSASDVWSYGCVLYEIWSLGLKPFE--H
       ||.. ...|....                        |...||.|.|||.|.         ..|....|||||.|....||...| .|.   .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SH---------NKEANKLDKG--------------YRMPPPSGCP--------------YLMYKLMILCWHPEPSQRPSFPEISRFL
|.             ..| .|              .|||.| .||               ..| ||  |||..|..||.| .. ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK312.AA UTK 511-766 35 7.6e-91 308.12 In-house 1-296 (296) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-296/296
Sequence Identity: 35% (104 aa)

IELKDYLGSGQFGFVHKGIWKG-------SLVAVKSLRNETTDIDRV----KFLQEAA---IMGQFS-HSNIVKLYGLVNEGDDNIMLVVELMPAGDLQK
..| . ||.|.|| |||. ..        ..|||| .... .. .      .|. ||.   .|.||. | |...|.|..  .   .|.|.|.|. |||..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLPSLRNNQSKEGLAES---LLTYCKEICSGMLYLSKRGFVHRDLAARNILLTAT-------NQCKIADFG---MSRDVEL--------EGYYVAQRG-T
|| . | ..  .... .   .| ..  | .|| ||. .|||||||||||.|...        ..|||||||   |||.|          | ||. ... .
YLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQD

MIPIKWTAPEALKFR-KYSSASDVWSYGCVLYEIWSLGLKPF-EHSHNKEANKLDKG--YRMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISRFL
..||.|.|||||  . .....|||||.| |..|||. | .|. ..|. . .  . .|  ||||.| .||  .|.||  |||..|. ||.|...  ..
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK312.AA Src 511-766 40 4.3e-90 305.62 In-house 1-255 (255) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-255/255
Sequence Identity: 40% (104 aa)

IELKDYLGSGQFGFVHKGIWKGSL-VAVKSLRNETTDIDRVKFLQEAAIMGQFSHSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKYLPSLRNNQSKEGL
| |.. ||.|||| | .|.|.|.  ||||.|.  |   .   ||||| || ...| ..|.||  . ...  |  | |.|  | |..||    . . ..  
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEE-PIYIVTEYMSHGSLLDYLKK--DGEGRHLH

AESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVEL-EGYYVAQRGTMIPIKWTAPEALKFRKYSSASDVWSYGCVLYEIWS
 . |.     . .|| ||... ..||||||||.|   .| ||.||||  | ..  .  |.|. | ..|||||||||. .....  |||||.|  |.|| .
LPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVT

LGLKPFEHSHNKEA-NKLDKGYRMPPPSGCPYLMYK-LMILCWHPEPSQRPSFPEISRFL
 |  | .  .|.|.  ....||||| |..||  .|. .|  ||| .| ||| |  .  ||
YGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK312.AA Eph 511-766 40 2e-88 297.17 In-house 1-264 (264) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-264/264
Sequence Identity: 40% (109 aa)

IELKDYLGSGQFGFVHKGIWKGS---------LVAVKSLRNETTDIDRVKFLQEAAIMGQFSHSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKYLPSLR
| ..  .|.|.|| | .|  | .         .||.| |.   |. .|. || ||.|||||.|.||..| | |  .   .| |.| |  | | ..   ||
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKS-RPVMIVTEYMENGSLDSF---LR

NNQSKEGLAESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVELEG----YYVAQRGTMIPIKWTAPEALKFRKYSSASDVW
..   .  .  |.   . | ||| |||  ..|||||||||||. .   ||..|||.|| .| ..     |  . |  |||.||||||. .||..||||||
QHDG-QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVW

SYGCVLYEIWSLGLKPFEHSHNKEA-NKLDKGYRMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISRFL
||| |. |. | | .|.    |..  .  ..||| ||| .||  ...||  ||. ....|| | .|  .|
SYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase AqueK312.AA SFK-Src 511-771 40 6.6e-86 254.5 In-house 1-259 (259) Show / Hide 
Range on Protein: 511-771
Range on HMM: 1-259/259
Sequence Identity: 40% (108 aa)

IELKDYLGSGQFGFVHKGIWKGSL-VAVKSLRNETTDIDRVKFLQEAAIMGQFSHSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKYLPSLRNNQSKEGL
|.|.  ||||||| | || | ..  |||| |.  ..  .   |||||..| .  | | ..||     |   |  . |||  | |  ||   .. . .   
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAE--EFLQEAQVMKKLRHPNLIQLYAVCTDGEP-IYIITELMKYGSLLDYL---HEPHGRSLR

AESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVELEGY-YVAQRGTMIPIKWTAPEALKFRKYSSASDVWSYGCVLYEIWS
   |     .. .|| ||    ||||||||||.|    | ||..|||||| .. .   | |. |   ||||||||| .  ..|  |||||.|  ..||  
MPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVT

LGLKPFEHSHNKEA-NKLDK--GYRMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISRFLLEQSN
.| .|..   |.|   ..|.  ||||| | .||  .||.|. ||  ||. || | |  .. .|   
YGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF-ESLKWQMEDFF
Kinase AqueK312.AA TK-Unique 511-766 37 7.2e-86 291.59 In-house 1-294 (294) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-294/294
Sequence Identity: 37% (109 aa)

IELKDYLGSGQFGFVHKGIWKG--------SLVAVKSLRNETTDIDRVKFLQEAAIMGQFS-HSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKYLPSLR
.|..|..|.|.||.|..|  .|        . |||| |. . || |. .||.|...| .   | |||...|   . |.. |.. | .| |.||.|| . |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

NN--------------------QSKEGLA-ESLLTYCKEICSGMLYLSK--RGFVHRDLAARNILLTATNQCKIADFGMSRDVELEGYYVAQRG-TMIPI
 .                    ...| .  ..|......|..|| ||..  ...|||||.|||.|||  ..|||.||||.|||. .| |. ...  .|||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTAPEALK--FRKY-SSASDVWSYGCVLYEIWSLGLKPFEHSHNKE-ANKLDKGYRMPPPSGC-PYLMYKLMILCWHPEPSQRPSFPEISRFL
.| |||.||   . | .. |||||.|....|| .||  |.    .|.  ... .||||| |..| .  ||.||. ||. ||..|||| .|   |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK312.AA Fer 511-767 32 2.1e-83 283.41 In-house 1-283 (283) Show / Hide 
Range on Protein: 511-767
Range on HMM: 1-283/283
Sequence Identity: 32% (94 aa)

IELKDYLGSGQFGFVHKG------IW-KGSL-----VAVKSLRNE-TTDIDRVKFLQEAAIMGQ-FSHSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKY
..|.. ||.| || |.||      .  |..      |.|| .. | .|.  . .|..|| || . ..| |.||.|| |   .  ||.| |... |.|..|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYG-VCVDEQPIMIVMEFCNGGSLDSY

LPSLRNNQSK-EGLAESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTA-TNQCK--IADFGMSRDVELEGYYVAQR--GTMIPIKWTAPEALKFRKY
|   . |..|   ..| .. .| ....|| || ... .|||.||||.|...  ...|  |.||||||. . .||    .   ...||.|.|||..... |
L---KKNKNKTVSDNE-KIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIY

SSASDVWSYGCVLYEIWSLGLKPFEH----SHNKEA------NKLDKGYRMPPPSGCPYLMYKLMI-LCWHPEPSQRPSFPEISRFLL
|...||||.|....|| . | .|..       ...       .. .|||.||.|...|  ....|   ||. .|..||.. || . | 
SPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK312.AA Abl 511-766 42 1.8e-76 254.49 In-house 1-252 (252) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-252/252
Sequence Identity: 42% (111 aa)

IELKDYLGSGQFGFVHKGIWK--GSLVAVKSLRNETTDIDRVKFLQEAAIMGQFSHSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKYLPSLRNNQSKEG
| .|. || ||.| | .|.||  .  ||||.|. .| ...   ||.||||| .  | |.|.| |     .    .. | |. | |  |   ||... .| 
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVH--EFLKEAAIMKEMKHPNLVQLLGVCTR-EPPFYIITEFMCYGNLLDY---LRECDREEL

LAESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVELEGYYVAQRGTMIPIKWTAPEALKFRKYSSASDVWSYGCVLYEIWS
 |  ||     | ||| || || |.|||||||| |.   .  |.||||..| .. .  | |. |   ||||||||.| . |.|| |||| .| .|.||  
PAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMK-DDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIAT

LGLKPFEHSHNKEA-NKLDKGYRMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISRFL
 |. |.     ..  .||.|||||  | |||  .|.||  ||. ... |||| || . .
YGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK312.AA Ack 511-766 38 2.6e-72 243.21 In-house 1-266 (266) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-266/266
Sequence Identity: 38% (103 aa)

IELKDYLGSGQFGFVHKGIWKG-----SLVAVKSLRNETTDID--RVKFLQEAAIMGQFSHSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKYLPSLRNN
| |   ||.| || |..| |.        ||||.|| .    .     ||.|.||| .  | ..|.|||.|   .  .|.| || | | |   |  ||  
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPM-LMMVTELAPCGSL---LDCLRK-

QSK--EGLAESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTAT-NQCKIADFGMSRDVEL-EGYYVAQRGT--MIPIKWTAPEALKFRKYSSASDVW
. .    |   |. .|  |..|| ||  ....||||||||||| .  .  ||.||| .|   . |.||. .      .|. | |||.|..|. |.|||||
HCRTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVW

SYGCVLYEIWSLGLKPFEHSHNKEA-NKLD-KGYRMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISRFL
..|  | |  | | .|. .    .   |.| .| | | |  ||   |..|  || ..|  ||.| .|  .|
MFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase AqueK312.AA CTKA 619-766 45 8.9e-60 199.48 In-house 139-290 (290) Show / Hide 
Range on Protein: 619-766
Range on HMM: 139-290/290
Sequence Identity: 45% (69 aa)

EICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVELE-GYYVAQRGTMIPIKWTAPEALKFRKYSSASDVWSYGCVLYEIWSLGLKPFEHS
.|  || ||. .||||||||.||.||   .  |||||| .|  . |  ||. .   ..|. | |||||.| |.|.|||||..| .|.|| | | ||. | 
QIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHM

HNKEANKLDKGY---RMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISRFL
  .|  ..  .    | |.|  ||  .| .| .|| .|| |||.|  . | |
SDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase AqueK312.AA S_TKc 511-766 25 8e-49 169.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

IELKDYLGSGQFGFVHKGIWKG--SLVAVKSLRNETTDIDRVKFLQEAAIMGQFSHSNIVKLYGLVNEGDDNIMLVVELMPA--GDLQKYLPSLRNNQSK
 |. . .|.| || |.|...|.   .||.| ..         ....| .|. .  | ||||||.   .  |.. .| |...   ||| .|. . . .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

EGLAESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQCKIADFGMSRDVELEGYYVAQRGTMIPIKWTAPEALKFRKYSS-ASDVWSYGCVLYE
 .. |    |...||... |. ..|..||||   ||||.   . ||.|||..| .         .       . ||| |   .|.  ..|.|| ||.|||
FPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

IWSLGLKPFEHSHNKEANKLDKGYRMPPPSGCPYLMYKLMILCWHPEPSQRPSFPEISR---------FL
  . |  ||.  ...  .|.            .  .  ..  |.. .|..||.  |. .         ..
MLC-GYPPFP-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK312.AA Pkinase 511-766 24 1e-40 145.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 511-766
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

IELKDYLGSGQFGFVHKGIWKGS--LVAVKSLRNETTDI--DRVKFL-QEAAIMGQFSHSNIVKLYGLVNEGDDNIMLVVELMPAG----DLQKYLPSLR
....  .||| || | |...||.  .|||| .. ....   |. ... .|..||  ..| |||.||. . . .|.| .| |... |    ||  |.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST--

NNQSKEGL---AESLLTYCKEICSGMLYLSKRGFVHRDLAARNILLTATNQC----KIADFGMSRD--VELEGYYVAQRGTMIPIKWTAPEALK-FRKYS
  ... ..    . .  |...|..|. |. ..|..||||   |||.  ....    ||.||| ..       . .    ||   . . ||| ..  ..|.
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGT---PWYMAPEVIRGGQYYG

SASDVWSYGCVLYEIWSLGLKPFEHS------HNKEANKLDKG--YRMPPPSGCP-------------------YLMYKLMILCWHPEPSQRPSFPEISR
...|.||.||.|||  . |  || ..        ..  ....|  .. . |  |.                     . ...  |... |..||....|  
PKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

F--L
   .
HPWF
Kinase AqueK312.AA CTKA 511-597 29 1.8e-14 44.87 In-house 1-100 (290) Show / Hide 
Range on Protein: 511-597
Range on HMM: 1-100/290
Sequence Identity: 29% (30 aa)

IELKDYLGSGQFGFVHKGIW------------KGSLVAVKSLRNETTDIDRVKFLQEAAIMG--QFSHSNIVKLYGLVNEGDDNIMLVVELMPAGDLQKY
      .|.|..| | . .             || .||||.|. . |. ||  || || .    .|.| |.. | |..   .     . | |. |||. |
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQ-HKPWHMIMEHMQYGDLHCY

L
|
L