Gene AqueK313 (A.queenslandica)

AqueK313

Species: A.queenslandica
Alias: AqueK313
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK313.AA Protein None 482 None Fasta, JSON
AqueK313.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of AqueK313.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH AqueK313.AA PH 3-89 18 7.1e-09 34.66 Pfam 12-92 (92) Show / Hide 
Range on Protein: 3-89
Range on HMM: 12-92/92
Sequence Identity: 18% (16 aa)

KKRKWKTYFFKVTGSTYFHYFPQSNHNKAKKEVFLTKVKGVTIPLSPPKGGEYVFEVRFTKDKPWVLSALTNEERHKWIETIYPQYK
|...|| ..| ... .. .|.  ..  . |. . | ..  ||.. ..  . ...|..|.   . ....| . ||.. |.. |    .
KRKSWKKRWFVLFN-NCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDN--KRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
PH AqueK313.AA PH 1-91 18 7e-06 26.86 SMART 7-82 (82) Show / Hide 
Range on Protein: 1-91
Range on HMM: 7-82/82
Sequence Identity: 18% (17 aa)

MYKKR-KWKTYFFKVTGSTYFHYFPQSNHNKAKKEVFLTKVKGVTIPLSPPKGGEYVFEVRFTKDKPWVLSALTNEERHKWIETIYPQYKPP
.|||  .|| ..| ...  ...|. ..   | |....|...  |.           .||... .   ..... . ||...|.. |    .. 
LYKKSKRWKKRWFVLFN-DCLYYYKDK---KPKGSIPLSDC-TVRE-P--------CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase AqueK313.AA TyrKc 218-474 35 1.2e-97 331.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-280/280
Sequence Identity: 35% (102 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQVAVKMLFDRNSQDSVLKEFNVMAST--MHPNIVRLYGLVVDS-----TAMGLRIVMEYLPYGDLKTYLKV
.. . ..| |.||.|. . .        |||||||| .   .   ..| ..| .    ||||||||| ....      .  | ||||| |.|||| ||. 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

SAK-KPVRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPAD------TSTYQSFT--SVP--LPIRWMSPEALVHKEFSE
. .  ....|........ || |...|..|||||||||.||||. |.||||| | ...  |      ...| . .  .    ||||||.||.. ...|..
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

ASDIWSYGVLQWEMFNPDETPYQS-----MEDAQVVMYVMNGKRLSPPRE--------CPYHISTIMESCWDSDPRKRPSFLKLTSLL
.||.||.||. ||.|   ..||       |....|. ||..|.|. .| .        ||  . .||..||. || .||.|  . ...
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK313.AA Pkinase_Tyr 218-474 34 1.6e-95 324.09 Pfam 1-270 (270) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-270/270
Sequence Identity: 34% (96 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQVAVKML--FDRNSQ---DSVLKEFNVMAST-MHPNIVRLYGLVV-D---STAMGLRIVMEYLPYGDLKTY
..    .|.|.||.|. . . .. ..  |.||||||      .|   .. ..| ..| .   ||||||||| .. .   .    . ||||| |.|||..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDY

LKV----SAKKPVRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPADTSTY-QSFTSVPLPIRWMSPEALVHKEFSEASD
|.       . .. .|... .....|| | ..|..|||||||||.||.|  ..||.|| | . .  ....| .. .. .|||.||.||.. ...|...||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

IWSYGVLQWEMFN-PDETP-YQSMEDAQVVMYV-MNGKRLSPPRECPYHISTIMESCWDSDPRKRPSFLKLTSLL
.||.||| ||.|   . .| |. | ...|. |.  .| |. .|. ||  | ..| .||. || .||.|  . . |
VWSFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK313.AA TK 218-474 20 3.3e-90 302.55 In-house 1-486 (486) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-486/486
Sequence Identity: 20% (101 aa)

LSNETIIGQGNFG---QVCVADYLPLVGSSS---------------------IQVAVKMLF--DRNSQDSVLK--------------EFNVMASTM----
.  .  .|.|.||   .|. . . .. .. .                     ..||||||   | .||.  .               | ..|.  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNIVRLYGLVVDSTAMG----------LRIVMEYLPYGD----LKTYLKVSAK---------------------------------------------
 ||||||||| ....  .           . ||||| |.||    |..||. . .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------KPVRTLVKYMIDVSMGMHYIAQK------GLIHRDLAARNVLVGERET-----------CKISDFS---
                                ....|. .. ... || |...|      ...||||||||.||||. .           |||.||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LIKELPADTSTYQSF-----------------------TSVPLPIRWMSPEALVHKE---------FSEASDIWSYGVLQWEMFN-PDETPYQSM
     | .... |.  | .                        ..  ||||||.||.| ...         |...||.||.||| ||.|   .|..|  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

ED---------AQVVMYVMNG--------------KRLSPPRECP--------------YHISTIMESCWDSDPRKRPSFLKLTSLL
 .         ..|. |. .|               |. .|  ||                .  .| .||. ||..||.|  | . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK313.AA TK-Unique 218-474 31 6.1e-77 261.93 In-house 1-294 (294) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-294/294
Sequence Identity: 31% (94 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQ--VAVKMLFDRNSQDS---VLKEFNVMASTM-HPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKTYLKVS
| .. .||.|.||||. ... .. .... |  |||||| |.... .    |||...| .   |||||...|  ..|.     |.|||.|.|.| .||. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTC

AKK------------------------PVR--TLVKYMIDVSMGMHYIAQ--KGLIHRDLAARNVLVGERETCKISDFSLIKELPADTSTYQSFTSVPLP
...                        |.   .|. ..... .|| |.|.  |. .||||.|||||..|. .|||.|| . ... ... .  . .. ..|
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

IRWMSPEALV--HKEF-SEASDIWSYGVLQWEMFNPDETPYQSMEDAQVVMYVMNGKRLSPPREC-PYHISTIMESCWDSDPRKRPSFLKLTSLL
||||.||.|   |. . .. ||.||.||| ||.|   ..|| .| .....  . .|.|.  | .| .  .  .|.||| ..| .|||| .... |
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK313.AA UTK 224-474 29 1.1e-72 247.84 In-house 7-296 (296) Show / Hide 
Range on Protein: 224-474
Range on HMM: 7-296/296
Sequence Identity: 29% (87 aa)

IGQGNFGQVCVADYLP-----LVGSSSIQVAVKMLFDRNSQD---SVLKEFN---VMASTM-HPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKTYLKVS
.|||.||.|..|.. .     ..   .. |...  ... ...    ...| .   .|.    |||..||.|.....    . ||.|| . ||| .||  .
LGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP--WMIVTEYMENGDLRSYLRRH

AKKP--------VRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGER-------ETCKISDFS---LIKELPA--------DTSTYQSFTSVPLPIR
...|         ....... |.. ||.|....|..||||||||.||..        ..|||.||    . .....        ..  |..    ..|||
RPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIR

WMSPEALVHK-EFSEASDIWSYGVLQWEMFNPDETPYQSMEDAQVVMYVMNG--KRLSPPRECPYHISTIMESCWDSDPRKRPSFLKLTSLL
||.||||.|   |...||.||.||. ||..    .||  | ..||.  |.||   |. .|..||  . ..| .|| .||..||.|  |.. .
WMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK313.AA Ack 218-474 35 1.2e-68 230.68 In-house 1-266 (266) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-266/266
Sequence Identity: 35% (95 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQVAVKMLFDR-----NSQDSVLKEFNVMASTMHPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKTYLKVSA
..    .|.| || |  ..     |. .|||||| | .      | .|. |.| ..| |  ||..|||||.| |. .  |. |.|  | | | . |.  .
ITLCEKLGDGCFGVVWRGEWTN-PGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPM--LMMVTELAPCGSLLDCLRKHC

K--KP-VRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERE-TCKISDFSLIKELPADTSTYQSFTSV--PLPIRWMSPEALVHKEFSEASDIWSY
.  .. . ||  .   . ||| |  .|..|||||||||.|.  .. . ||.|| |   |.     | .   .  ..|. |. ||.| |. || |||.|..
RTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMF

GVLQWEMFNPDETPYQSMEDAQVVMYVM-NGKRLSPPRECPYHISTIMESCWDSDPRKRPSFLKLTSLL
||  ||||   | |.  .  .|.   .  .| ||  |  ||  | ..|. ||. .| .||.|  .  .|
GVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase AqueK313.AA Src 218-474 33 2e-63 214.35 In-house 1-255 (255) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-255/255
Sequence Identity: 33% (89 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQVAVKMLFDRN-SQDSVLKEFNVMASTMHPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKTYLK---VSAK
.  .  .|||.|| |  . .       ...|||| |   . |..  |.| ..| .  |...|.||  . .       || ||   | | .|||      .
IKLCRKLGQGQFGEVWMGYWN-----GNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEE--PIYIVTEYMSHGSLLDYLKKDGEGRH

KPVRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPADTSTYQSFTSVPLPIRWMSPEALVHKEFSEASDIWSYGVLQWEM
 ....|.     |. || |. .. .||||||||||||||   ||. || | . .  |   | . .   .||.|. |||. .  |.  || ||.|.| .|.
LHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEI

FNPDETPYQSMEDAQVVMYVMNGKRLSPPRECPYHIST-IMESCWDSDPRKRPSFLKLTSLL
.    .||  |. ..|.  |..| |.  |..||  .   ||  ||..||..|| |  | . |
VTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK313.AA Csk 218-474 39 2.6e-63 214.88 In-house 1-251 (251) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-251/251
Sequence Identity: 39% (102 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQVAVKMLFDR--NSQDSVLKEFNVMASTMHPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKTYLKVSAKKP
|     ||.|.|| | . .|.         ||||.. .      .. | |  ||    ||| |.| |.....   .| |||||.  | |  ||    .. 
LHLGECIGHGEFGDVMQGEYQ------NRKVAVKCIKCDGNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKN-HLYIVMEYMSKGNLVDYLRSRGRHV

V--RTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPADTSTYQSFTSVPLPIRWMSPEALVHKEFSEASDIWSYGVLQWEM
.  | | |. .||  || |  || ..||||||||.|| |    |.||| | ||   ..|.    ||  .|| | .|||| ||.||  ||.||.|.| || 
ITRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKE---ECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEI

FNPDETPYQSMEDAQVVMYVMNGKRLSPPRECPYHISTIMESCWDSDPRKRPSFLKLTSLL
.     ||  .  . || .|  | |  .|  || |. ..|..||. .|.|||.|... . |
YSFGRVPYPRIPLKDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL
Kinase AqueK313.AA Eph 218-474 36 4.2e-62 207.37 In-house 1-264 (264) Show / Hide 
Range on Protein: 218-474
Range on HMM: 1-264/264
Sequence Identity: 36% (98 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSI---QVAVKMLFDRNSQDSVLKEFNVMASTM----HPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKTYLKV
.  |..|| | || ||     .  |   .    ||.|.| .  . ..   .|   ||.|    ||||.|| | |  |  .   || ||   | | ..|. 
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKA-GYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPV--MIVTEYMENGSLDSFLRQ

SAKK-PVRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPADTS---TYQSFTSVPLPIRWMSPEALVHKEFSEASDIWSY
   .  |  ||  .  .  || | .  . .||||||||.|| ..  ||.||| |  .|  |.|   || .  .   ||||  |||. .. |. |||.|||
HDGQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSY

GVLQWEMFNPDETPYQSMEDAQVVMYVMNGKRLSPPRECPYHISTIMESCWDSDPRKRPSFLKLTSLL
|.. ||     | ||  | .  |.  .. | || ||..||  .  .|  ||  |. .|| | .. | |
GIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase AqueK313.AA CTKA 217-474 32 1.2e-61 205.88 In-house 2-290 (290) Show / Hide 
Range on Protein: 217-474
Range on HMM: 2-290/290
Sequence Identity: 32% (94 aa)

CLSNETIIGQGNFGQVCVADYLPLVG------SSSIQVAVKMLFDRNSQDSV---LKEFNVMA--STMHPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLK
| . .  || | .|||  |   |              |||||| |      .   | | .| .     |||..|| |..  .    .  .||...||||.
CIMFK--IGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKP--WHMIMEHMQYGDLH

TYLKVSAKKP--------------------VRTL--VKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPADTSTYQSFTSVPLP
 ||. ..  .                    |..   |    ..  || | |  |..|||||.||.|.|   . ||.|| . . |      | .  .  .|
CYLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMP

IRWMSPEALVHKEFSEASDIWSYGVLQWEMFNPDETPYQSMEDAQVVMYVMNG--KRLSPPRECPYHISTIMESCWDSDPRKRPSFLKLTSLL
.|||.||||    || |||.|..||| ||..   |.|.  | |  |.  .  .  .|| .|| ||  . . |. ||   | .||.|  |   |
VRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase AqueK313.AA Fer 218-475 28 5.1e-59 199.65 In-house 1-283 (283) Show / Hide 
Range on Protein: 218-475
Range on HMM: 1-283/283
Sequence Identity: 28% (80 aa)

LSNETIIGQGNFGQVCVA--DYLPLVGSSSI----QVAVKML----FDRNSQDSVLKEFNVMAS-TMHPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKT
   . ..| |.|| |. .  .   . | ..      |.||..     ..  .  ...| ..| .   |||.|..||  ||  .  . ||||. . |.|..
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQP--IMIVMEFCNGGSLDS

YLKVSAKK--PVRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGE-RETCK--ISDFSLIKELPADTSTYQSF-TSVPLPIRWMSPEALVHKEFSEA
||| . .|  ........ .... || |. .|. ||||.||||.|...    .|  |||| . ...  ....|.   ..  .||||..||..  ...|..
YLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPK

SDIWSYGVLQWEMFNPDETPYQS----MEDAQV----VMY-VMNGKRLSPPRECPYHISTIME-SCWDSDPRKRPSFLKLTSLLT
.|.||.||. || |.  ..||      |  ..|    ..  . .|... .| ..|  |  ||. .||. || .||.. ..   | 
TDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase AqueK313.AA Syk 218-468 35 7.8e-58 197.65 In-house 1-257 (257) Show / Hide 
Range on Protein: 218-468
Range on HMM: 1-257/257
Sequence Identity: 35% (92 aa)

LSNETIIGQGNFGQVCVADYLPL---VGSSSIQVAVKMLF----DRNSQDSVLKEFNVMASTMHPNIVRLYGLVVDSTAMGLRIVMEYLPYGDLKTYLKV
|     ||.|||| |    |.        . |.||.|||     . ....  . | .||.   || |||. |      |  .  |||  . | .  ||. 
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKADHNQPADKQEFMREAQVMCQLDHPCIVRMIGI---CHAEMMMMVMEMAELGPMHKYLQQ

SA-KKPVRTLVKYMI-DVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPADTSTYQSFTSVPLPIRWMSPEALVHKEFSEASDIWSYGV
     ...  .. .   |.|||.|   |  .||||||||||   |   ||||| . | | || . ||. |    |..|  ||      || .||.||.||
HRHEITANNVLELWHTQVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGV

LQWEMFNPDETPYQSMEDAQVVMYVMNGKRLSPPRECPYHISTIMESCWDSDPRKRPSFL
. ||||     || .|  . |.  . ||.|.. | .||  .  .| .|| ...  || |.
TMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase AqueK313.AA S_TKc 218-479 24 1.2e-35 125.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQVAVKMLFDRNSQDSVLKEFNVMASTMHPNIVRLYGLVVDSTAMGLRIVMEYLPY--GDLKTYLKVSAK--
     .||.| ||.|. .        .  .||.|..      .....| ... .  |||||.||.  .|     | .||||..   |||..|.|   .  
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----KPVRTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETCKISDFSLIKELPADTSTYQSFTSVPLPIRWMSPEALVHKEFSE-ASDIWSYGV
     |  .  .||  .  .. |. ..| |||||   |.|. |  . ||.|| | ..|          |..     .|.|| |    ..  ..|.|| |.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LQWEMFNPDETPYQSMEDAQVVMYVMNGKRLSPPRECPYHISTIMESCWDSDPRKRPSFLKLTS----LLTHTNM
. .||.   ..|..   . |... ..           .     ... |.. ||.|||.  ..         |  .
ILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK313.AA Pkinase 218-476 22 1.8e-33 119.41 Pfam 1-290 (293) Show / Hide 
Range on Protein: 218-476
Range on HMM: 1-290/293
Sequence Identity: 22% (70 aa)

LSNETIIGQGNFGQVCVADYLPLVGSSSIQVAVKMLFDRNSQDSVLK------EFNVMASTMHPNIVRLYGLVVDSTAMGLRIVMEYLPYG----DLKTY
.  . .||.|.||.|. .       .....|||| .  |.  .....      |  .|..  ||||||||. . |.. .   .||||.. |    ||..|
YHIGRKIGSGSFGCVYKCHHK----GTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDY

LKVSAKKPV----RTLVKYMIDVSMGMHYIAQKGLIHRDLAARNVLVGERETC----KISDFSLIKELPADTSTYQSFTSVPLPIRWMSPEALV-HKEFS
.........    ... .||  .  |. |. ..| |||||   |.|. .. ..    ||.|| | | .   .  .. .|..   ...|.|| .  ... .
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

EASDIWSYGVLQWEMFNPDETPYQ------SMEDAQVVMYVMNGKRLSPPRECP---------------------YHISTIMESCWDSDPRKRPSFLKLT
 ..|.||.|.. .||..  ..|..      .  | .....   |..|. ... .                          ....|.. || |||.    .
PKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AE

SLLTH
 .| |
QILQH