Gene AqueK318 (A.queenslandica)

AqueK318

Species: A.queenslandica
Alias: AqueK318
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK318.AA Protein None 1089 None Fasta, JSON
AqueK318.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of AqueK318.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PB1 AqueK318.AA PB1 19-101 15 1e-06 26.47 Pfam 1-86 (86) Show / Hide 
Range on Protein: 19-101
Range on HMM: 1-86/86
Sequence Identity: 15% (14 aa)

LVEVKSKFEYEYRRFSIDRTQLTQYDELSALIKESHNLPTDMPFTVSYTNPKNDDILPINNDKNMNSAFQTAMP-----FIKLFIYRE
 |..|... .. |||.|.    . ...| ..... ....   .|. .| .  .|| ..|..| ..  ..... .      ..|..   
TVRIKCRYGGDIRRFIIHVRRNISFEDLMHKVEQRCKCD--HTFKYQYPDEDGDDWVTITCDEDLQEMMEEYRSSEKSMTLRLHVFPS
PB1 AqueK318.AA PB1 19-101 19 7e-06 26.75 SMART 1-95 (95) Show / Hide 
Range on Protein: 19-101
Range on HMM: 1-95/95
Sequence Identity: 19% (19 aa)

LVEVKSKF-EYEYRRFSIDRTQLTQYDELSALIKESHNLPTDMPFTVSYT--NPKNDDILPINNDKNMNSAFQ-----------TAMPFIKLFIYRE
 |.|| ..   . ||||..|   . .|.| ..... .... | |||..|   .  .|  ..|..| ..  ...           . .....|...  
PVDVKCRYVGGDTRRFSVPR--DWSFDDLMSKVAQRCGHDNDQPFTLKYQLPDEDGDAWVTITCDEDLQEMMEMYDSLESQNKSSCWKTLRLHVFPF
PDZ AqueK318.AA PDZ 166-249 29 5.6e-16 60.32 SMART 1-80 (80) Show / Hide 
Range on Protein: 166-249
Range on HMM: 1-80/80
Sequence Identity: 29% (28 aa)

RPLGFYIRDGTSVRVTPYGLEKVPGIFISRLVPGGLAEGTG-----LLSVNDEIIEVNG-IETLGKSLDQVTDMMVANSQ-----NLIITVKPST
 .||| |..               |||||..|||| ||  |     .| ..|.|.|||| . . ... .|. ||. . ..      . .||..  
GGLGFSIVG---------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG
PDZ AqueK318.AA PDZ 156-246 29 5.3e-13 47.11 Pfam 1-86 (86) Show / Hide 
Range on Protein: 156-246
Range on HMM: 1-86/86
Sequence Identity: 29% (27 aa)

RVKLVKQSTDRPLGFYIRDGTSVRVTPYGLEKVPGIFISRLVPG-GLAEGTGLLSVNDEIIEVNGIETLGKSLDQVTDMMVANSQ-NLIITVK
 |.| || .  .||| |. |.. |         .||.||...|| | ||  | . ..| ||..||  . . ..|.. ...   ..  . .|..
QVTLEKQDKRGGLGFSIKGGNDQRH-------DQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ
Pkinase_Tyr AqueK318.AA Pkinase_Tyr 783-1043 43 1.9e-125 425.48 Pfam 1-270 (270) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-270/270
Sequence Identity: 43% (118 aa)

IQITKYLGSGQFATVNKAQWI--TGGGDVSVAVKMLKAGSSEQE--KVKFLQEAAINGQF-HHLNVVRLLGVVT-VGEP--VIIVLELLGNGNLKKFLTS
|.. | ||.|.| .| |. |    ..... ||||||| |.....  . .|..||.|  |. || |.|||.||.|  |||  ..||.|.  .|.|...| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

KRPVGCVVPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDLQENEYY--ISQGGLVPIKWTALEAIFYRKYSTASDV
.|      |  ..  |...| |||.||.||. | .|||||||||.||.|....|..||||.||... .||   ..|| .||||.|.|.|.|.|..|.|||
HR--EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSYGVLLFEIWSLGRKP-FSSLTNEKYIEKI-DEGERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQYL
||.|||..|| ..|..| .  ..||  .|.| ..|.|...|..||   |.||..|||. | |||.|. . . |
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK318.AA TyrKc 783-1043 38 1.9e-120 407.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-280/280
Sequence Identity: 38% (115 aa)

IQITKYLGSGQFATVNKAQWITGGGDVSVAVKMLKAGSSEQEKVKFLQEAAINGQF--HHLNVVRLLGVVTVG-------EPVIIVLELLGNGNLKKFLT
|.  | ||.|.| .| |..|.     . |||||||...    .  |..|| |  ..  || |.|||.||.| .       ||. ||.|.  .|.||..| 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SKRPVGCVVPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDLQEN-------EYYISQ---GGL--VPIKWTALEAI
..||         .  |..|| |||.||.||..| .|||||||||.||.|....|..|||||||. .        .|| ..   ||   .||.|.|.|.|
KHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

FYRKYSTASDVWSYGVLLFEIWSLGRKPFSS-----LTNEKYIEKIDEGERLAPPPG--------CPRSFYQLMMDCWHPSPPDRPSFTSLCQYL
.|.|..|.|||||.||...|| ..| .| .      ..|.  ||....|.|. .||         ||   ||.| .|||  | |||.|. .....
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK318.AA TK 783-1043 24 8.10000000001e-110 369.45 In-house 1-486 (486) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-486/486
Sequence Identity: 24% (119 aa)

IQITKYLGSGQFA---TVNKAQWITG-----------------------GGDVSVAVKMLKAGSSEQEKV-------------KFLQEAAINGQFH----
|.. | ||.|||    .| |..|...                       || . |||||||.|......              .||.||..  ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HLNVVRLLGVVTVG------------EPVIIVLELLGNGN----LKKFLTSKRPVGCVVPEELPN----------------------------------
 | |.|||.||.| |            ||..||.|.  .|.    |...| ..|| .   ... .|                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------------------------------LLCNFCKQIASGMDYLAKKTF------IHRDLAARNILVSEQLI-----------CKVADFG---
                                    |. .| |||.|| ||..| .      .||||||||.||.|...           ||.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRDLQEN-EYYISQ------------------------GGLVPIKWTALEAIF---------YRKYSTASDVWSYGVLLFEIWSLGRKPFSS-L
     |.||.... .|| ..                        || .||.|.| |...         |.|..|.|||||.|||..||...|..|.   .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------EKYIEKIDEG--------------ERLAPPPGCP--------------RSFYQLMMDCWHPSPPDRPSFTSLCQYL
.|         .  .|.. .|               |...||.||                .|.||..|||. | |||.|. | ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK318.AA UTK 783-1043 37 4e-102 345.58 In-house 1-296 (296) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-296/296
Sequence Identity: 37% (110 aa)

IQITKYLGSGQFATVNKAQWITGG---GDVSVAVKMLKAGSS-EQEKV---KFLQEAA---INGQFH-HLNVVRLLGVVTVGEPVIIVLELLGNGNLKKF
.|. . ||.|.| .|.|| . .     ... |||| ...... .||.    .|. ||.   . .||| | ||.||.||.| .|| .||.|.  ||.| ..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LTSKRP-VG-CVVPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQ-------LICKVADFG---LSRDLQ---------ENEYYISQG-G
| . || .. | .   |  .|| .. .||.|| ||. . |.||||||||.|| ..       ..||.||||   .||...         | .|| .|. .
LRRHRPTPPACPHWLTLHQRLC-MAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQD

LVPIKWTALEAIFYR-KYSTASDVWSYGVLLFEIWSLGRKPFSSLTNEKYIEKIDEG--ERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQYL
 .||.|.| ||. .. ...|.|||||.||...|||. ||.|.  ..|.. .. . .|   |...|..||.. |.||..|||..| .||.|  | | .
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK318.AA Eph 783-1043 44 2.8e-99 334.18 In-house 1-264 (264) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-264/264
Sequence Identity: 44% (121 aa)

IQITKYLGSGQFATVNKAQWI--TGGGDV---SVAVKMLKAGSSEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGNGNLKKFLTSKRP
|.|.| .|.|.|  | .       |  .|    ||.|.||||..|.... || ||.| ||| | |..|| |||| ..|| || |   || | .||  .. 
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFL--RQH

VGCVVPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDLQENE----YYISQGGLVPIKWTALEAIFYRKYSTASDVW
 | ...  |  .|    . ||||| ||.   ..|||||||||||...|.|||.|||||| |....     | ..|| .||.||| ||| |||...|||||
DGQFTVIQLVGML----RGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVW

SYGVLLFEIWSLGRKPFSSLTNEKYIEKIDEGERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQYL
|||... |. | | .|.  ..| . |. |..| || ||..||.. .|||.|||.  . .|| |...   |
SYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase AqueK318.AA Src 783-1043 40 2.9e-96 326.12 In-house 1-255 (255) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-255/255
Sequence Identity: 40% (107 aa)

IQITKYLGSGQFATVNKAQWITGGGDVSVAVKMLKAGSSEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGNGNLKKFLT-SKRPVGCV
|.  . ||.|||  | .. |    | . |||| ||.|.   .   ||||| |  .. | ..|.|. |.. .||. || |.  .|.| ..|  ...   . 
IKLCRKLGQGQFGEVWMGYWN---GNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLH

VPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDLQ--ENEYYISQGGLVPIKWTALEAIFYRKYSTASDVWSYGVLL
.|.     |  .  |.|.||.|| .. .|||||||||.||.|...|||||||| | ..  ..||  ..|  .|||||| ||| |..... |||||.|.||
LPQ-----LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILL

FEIWSLGRKPFSSLTNEKYIEKIDEGERLAPPPGCPRSFYQ-LMMDCWHPSPPDRPSFTSLCQYL
 || . || |    ||.  ..... | |.  |..|| ..|. .|. ||| .| .|| |  |...|
TEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK318.AA SFK-Src 783-1039 43 3.7e-93 276.39 In-house 1-251 (259) Show / Hide 
Range on Protein: 783-1039
Range on HMM: 1-251/259
Sequence Identity: 43% (113 aa)

IQITKYLGSGQFATVNKAQWITGGGDVSVAVKMLKAGS-SEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGNGNLKKFLTSKRPVGCV
|.  | ||||||  | |  |    .   |||| || |. |..|   |||||..  .  | | ..|  | | |||. |. ||. .| |  .| . .  .  
IRLEKKLGSGQFGDVWKGRW---NNTTEVAVKTLKPGAMSAEE---FLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLR

VPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDL-QENE-YYISQGGLVPIKWTALEAIFYRKYSTASDVWSYGVLL
.|     .|     |.|.|| ||  . |.||||||||.|| .  .|||.|||.|| | |..| |   .|   |||||| ||  . ..|. |||||.|.|.
MP-----QLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILM

FEIWSLGRKPFSSLTNEKYIEKIDE--GERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSL
 ||  .||.|.  .||   . ..|   |.|.  ||.||  .|..|.|||   | ||| | ||
MEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESL
Kinase AqueK318.AA TK-Unique 783-1043 33 1.7e-88 300.34 In-house 1-294 (294) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-294/294
Sequence Identity: 33% (99 aa)

IQITKYLGSGQFATVNKAQWITGG---GDV-SVAVKMLKAGSSEQEKVKFLQEAAINGQFH-HLNVVRLLGVVT-VGEPVIIVLELLGNGNLKKFLTSKR
. . ...|.|.| .| ...  ..    ..  .|||||||.......| .||.|.... .   | |.|..||. |  .||. |..| . .||| ..| ..|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PV-----------------GCVVPEE-LP-NLLCNFCKQIASGMDYLAK--KTFIHRDLAARNILVSEQLICKVADFGLSRDLQENEYYISQG--GLVPI
|.                    ...| .   .| .|..|||.|| |||.  | ..||||.|||.|..| ..||..|||..||.. |. |....  | .||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTALEAIF--YRKY-STASDVWSYGVLLFEIWSLGRKPFSSLTNEKYIEKIDEGERLAPPPGC-PRSFYQLMMDCWHPSPPDRPSFTSLCQYL
.| |.|..   .. | .| |||||.|||..|| .||  |.... ... .|.| .| |.  |..| .. .|.||  ||. .| .||||... . |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK318.AA Ack 783-1043 39 4.9e-80 269.67 In-house 1-266 (266) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-266/266
Sequence Identity: 39% (108 aa)

IQITKYLGSGQFATVNKAQWIT-GGGDVSVAVKMLKAG--SSEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPV-IIVLELLGNGNLKKFLTSKRPV
|   . ||.| |. | ...| . ||  ..|||| |. .  .. ..   ||.|.||  .  | ..||| |||  . |    | ||   | |   |.   ..
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVV-LDQPMLMMVTELAPCGSLLDCLRKHCRT

GCV-VPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQ-LICKVADFGLSRDLQENEY-YISQGGL---VPIKWTALEAIFYRKYSTASDV
    ..     .||.|| |||.|| ||  | .|||||||||||.  .    |..||||.| | .||  | ...     ||. | | |.. .|. | ||||
AFFLIH-----TLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDV

WSYGVLLFEIWSLGRKPFSSLTNEKYIEKID-EGERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQYL
|..|| | |  | |..|.  .. .  ..||| |||||  |. ||.  ||.|| || . | |||.| ..  .|
WMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase AqueK318.AA Frk 783-1047 41 4.2e-78 265.78 In-house 1-260 (260) Show / Hide 
Range on Protein: 783-1047
Range on HMM: 1-260/260
Sequence Identity: 41% (111 aa)

IQITKYLGSGQFATVNKAQWITGGGDVSVAVKMLKAGSSEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGNGNLKKFLTSKRPVGCVV
||. . ||||||  |   .|      . |||| ||.|. . .   ||.|| |  .  |  ...|  | || ||..|. ||. .| |...| .    |  .
IQLIRRLGSGQFGEVWEGLWNN---TTPVAVKTLKPGTMDPN--DFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQC

PEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSR-DLQENE--YYISQGGLVPIKWTALEAIFYRKYSTASDVWSYGVLL
  ... |. .   |.|.|| || .. .|||||||||.|| |..|||.||||| |  ...||  |   .|  .|||||| ||. | |... |||||.|.||
--QMQQLV-DMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILL

FEIWSLGRKPFSSLTNEKYIEKIDEGERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQYLSQPV
 ||   || |.. .|| . .. .|.| |.  ||.||  .|..|..|||  |  || |  |   | .  
TEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK318.AA InsR 783-1045 34 9.3e-78 260.74 In-house 1-278 (278) Show / Hide 
Range on Protein: 783-1045
Range on HMM: 1-278/278
Sequence Identity: 34% (96 aa)

IQITKYLGSGQFATVNKA---QWITGGGDV--SVAVKMLKAGSSEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGNGNLKKFLTSKRP
| . . .| | | .|        . ....    .|.| .... |  |.. ||.|| .  .| . .|||||||.. |.|  .| |.   |.|| .| |.||
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

VGC----VVP----EELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDLQENEYY-ISQGGLVPIKWTALEAIFYRKYST
       ...       .  . .   .|..|| ||| | |.|||||.|| .|.. . .|..|||. ||. |  ||  . .|. |. | | | .   ...|
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTT

ASDVWSYGVLLFEIWSLGRKPFSSLTNEKYIEKI-DEGERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQYLSQ
.|||||.||.|.|. .||  |   | ||   . |  .|  | || .||   ..||| ||. .| .||.|. . .|| .
HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK318.AA Musk 892-1043 43 6.3e-62 203.33 In-house 130-282 (282) Show / Hide 
Range on Protein: 892-1043
Range on HMM: 130-282/282
Sequence Identity: 43% (66 aa)

NFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDLQENEYYISQG-GLVPIKWTALEAIFYRKYSTASDVWSYGVLLFEIWSLGRKPF
.  |||| || ||  . |.||||| || |. |.   |.|||||||     .||  ..   .|| |...|.|.| .....||||.|||.| || | .  |.
CMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYALQPY

SSLTNEKYIEKIDEGERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQYL
  .| |  |  | .| .|. |  || . ||||  ||   | |||.|... . .
YGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK318.AA S_TKc 783-1043 22 1.7e-45 158.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

IQITKYLGSGQFATVNKAQWITGGGDVSVAVKMLKAGSSEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGN--GNLKKFLTSKRPVG-
 .| . .|.| |..| |....    .  ||.|..|         ....| .|  . || |.|.|..|    . . .|.|....  |.|.... .... | 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-CVVPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLICKVADFGLSRDLQENEYYISQGGLVPIKWTALEAIFYRKYST-ASDVWSYGV
 .. ||      . ...||.....|. .. .|||||   |||..|    |..||||.| |            .   . | | .   .|.. ..|.|| |.
RFPFPE-H---ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LLFEIWSLGRKPFSSLTNEKYIEKIDEGERLAPPPGCPRSFYQLMMDCWHPSPPDRPSFTSLCQ---------YL
.|.|  . |. ||.  . .. ..||            .... .... |..  | .||.   . |         ..
ILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK318.AA Pkinase 783-1043 20 4.5e-36 128.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 783-1043
Range on HMM: 1-293/293
Sequence Identity: 20% (63 aa)

IQITKYLGSGQFATVNKAQWITGGGDVSVAVKMLKAGSSEQEKV--KFL-QEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGNG----NLKKFLT--
..| . .||| |..| |....  |    |||| .|  . . .|   ... .|..|   ..| |.|||..... .  . .|.|....|     |. ...  
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

SKRPV--GCVVPEELPNLLCNFCKQIASGMDYLAKKTFIHRDLAARNILVSEQLIC----KVADFGLSRDLQENEYYISQGGLVPIKWTALEAIF-YRKY
.....          .. ......||..|..|. .. .|||||   |||....  .    |..||||.. ...  .   ..  . . . | | |  ...|
RHGCFYFS-------EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

STASDVWSYGVLLFEIWSLGRKPFSSL----TNEKYIEKIDEGERLAPPPGCP-----------------------RSFYQLMMDCWHPSPPDRPSFTSL
....|.||.|..|.|  . || ||..     .    ...|..  .  ..  .|                       ... ... .|... | .||... .
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

CQY--L
.|   .
LQHPWF
Kinase AqueK318.AA Musk 783-877 36 3.6e-18 56.43 In-house 1-98 (282) Show / Hide 
Range on Protein: 783-877
Range on HMM: 1-98/282
Sequence Identity: 36% (36 aa)

IQITKYLGSGQFATVNKAQ---WITGGGDVSVAVKMLKAGSSEQEKVKFLQEAAINGQFHHLNVVRLLGVVTVGEPVIIVLELLGNGNLKKFLTSKRP
|   . .| | |  |  |     . .  ...|||||||.  |.| .  |  ||..  .| | |.|.||||  || |    .| .  | |  || |  |
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSP