AqueK325

Species: A.queenslandica
Alias: AqueK325
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK325.AA Protein None 662 None Fasta, JSON
AqueK325.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of AqueK325.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK325.AA Pkinase_Tyr 349-616 35 2.1e-113 384.73 Pfam 1-270 (270) Show / Hide
Range on Protein: 349-616
Range on HMM: 1-270/270
Sequence Identity: 35% (101 aa)

ITFDKEIGKGQFGTVFAGTWY-LAGGDRRPVAIKRLSVQASEEE--KSKFLREGARMMQF-FHPNVVKLLGVAT-VHTP--FLLVQELMSKGDLKSYLKG
|||.|..|.|.||.|. |||. . .... |||.| |  .|..|.  . .|.|| . |.|.  |||.|.|.|| |    |   ..| |.| .|||..||. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

SRPQLDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTRAA----NHVFDLNKTEQIPLRWTAPEAFKLKD
 |         . .. .....||..|..||.|| .|  ||..||||||||.|...|...||.|||..|.     .  .   .   .| .|.|||... . 
HR---------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK

YSEKSDVYSYGMVLYEIWSLGRKP-FPRLYQNQEIVDFI-DQRGLLPPPPGCPREVYSLMVTCWNPNPSLRMSFDSICNDY
...||||.|.| ...|| ..|..| .| .  |.|....| .... .|.|..|| |.|.||  ||...|. | .|  | .. 
FTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

TyrKc AqueK325.AA TyrKc 349-616 34 2.2e-110 373.91 SMART 1-280 (280) Show / Hide
Range on Protein: 349-616
Range on HMM: 1-280/280
Sequence Identity: 34% (103 aa)

ITFDKEIGKGQFGTVFAGTWYLAGGDRRPVAIKRLSVQASEEEKSKFLREGARMMQF--FHPNVVKLLGVATVH-------TPFLLVQELMSKGDLKSYL
||..|..| |.||.|. |||.      ..||.| |   |    .  |.||   |...   |||.|.|.||.| .        | ..| |.|..||||.||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KGSRPQLDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTRAANHV------FDLNKT-----EQ--IPLR
. .||.             ....||.|| .||.||..|  ||..||||||||.|...|...||.|||..|.  .        |  ..     .   .|.|
RKHRPK------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR

WTAPEAFKLKDYSEKSDVYSYGMVLYEIWSLGRKPFPRL----YQNQEIVDFIDQRGLLPPPPG--------CPREVYSLMVTCWNPNPSLRMSFDSICN
|.|||... . ...||||.|.| ...|| ..| .| |        |||.. ...|.. .|.||         || |.|..| .||. .|. | .|  |. 
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

DY
. 
CF

Kinase AqueK325.AA TK 349-616 22 3e-104 350.44 In-house 1-486 (486) Show / Hide
Range on Protein: 349-616
Range on HMM: 1-486/486
Sequence Identity: 22% (112 aa)

ITFDKEIGKGQFG---TVFAGTWYLAG----------------------GDRRPVAIKRLSV--QASEEEKSK-----------FLREGARMMQFF----
||. |..|.||||   .|. |.|.  .                      | . |||.| |     .|.||.             ||.| . |...     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVKLLGVATVH------------TPFLLVQELMSKGD----LKSYLKGSRP-------------------------------QLDSNDPVPVRDV-
 |||.|.|.|| | .             |...| |.|..||    |..||. .||                                ..||.|  ...  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

--------------------------------PSPQQLLKFCRDIASGMRHLVTK------NFVHRDLAARNVLLNDNLI-----------CKIADFGMT
                                ....||| .|..||.||..|  |      |||||||||||.|...|..           |||||||..
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

RAAN--HVFDLNK--------------------------------TEQIPLRWTAPEAFK---------LKDYSEKSDVYSYGMVLYEIWSLGRKPFPRL
|.    .  |...                                  ..|.||.|||...          . ...||||.|.| ...||...|..|..  
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

YQN---------QEIVDFIDQ--------------RGLLPPPPGCP--------------REVYSLMVTCWNPNPSLRMSFDSICNDY
  |         ||..... .              |  .|.||.||               |.| ||  ||...|. | .|. . .  
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK325.AA UTK 349-610 33 9.7e-86 291.16 In-house 1-290 (296) Show / Hide
Range on Protein: 349-610
Range on HMM: 1-290/296
Sequence Identity: 33% (100 aa)

ITFDKEIGKGQFGTVFAGTWYLAG--GDRRPVAIKRLSVQAS-EEEKS---KFLREGA---RMMQFF-HPNVVKLLGVATVHTPFLLVQELMSKGDLKSY
. . ...|.|.||.|. ...  .   .    ||.| ... |. . |.    .|..| .    |.||  ||||..|.|| |   |...| |.|..||| ||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LKGSRPQLDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDN-------LICKIADFG---MTRAANH-----------VFDL
|  .||...     . ..  .  |.|....|||.|| .| ...||||||||||.|....       ..|||||||   |.|..|             .  
LRRHRPTPP-----ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA

NKTEQIPLRWTAPEAFKLK-DYSEKSDVYSYGMVLYEIWSLGRKPFPRLYQNQEIVDFIDQRG--LLPPPPGCPREVYSLMVTCWNPNPSLRMSFD
.  ...|.||.||||.    ....||||.|.| |..|||. ||.|.|  . |.... ..  .|  ..|.|..||..|| ||. ||...|. | .|.
QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPG-MSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFE

Kinase AqueK325.AA TK-Unique 349-616 34 1.4e-83 284.02 In-house 1-294 (294) Show / Hide
Range on Protein: 349-616
Range on HMM: 1-294/294
Sequence Identity: 34% (101 aa)

ITFDKEIGKGQFGTVFAGTWYLAG---GDRRPVAIKRLSVQASEEEKSKFLREGARMMQFF-HPNVVKLLGVATVHT-PFLLVQELMSKGDLKSYLKGSR
......||.|.||.|. |.        .... ||.| |   |....|..||.| . |..   |||.|..||. |  . |.... | ...|.| .||. .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PQ-------------LDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVT--KNFVHRDLAARNVLLNDNLICKIADFGMTR--AANHVFDLN-KTEQIPL
|.             .... . | ..  ||..|. |. .||.|| .|    |..|||||.||||||.....|||.||||.|   .|.| . . . . ||.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWTAPEAFK--LKDY-SEKSDVYSYGMVLYEIWSLGRKPFPRLYQNQEIVDFIDQRGLLPPPPGC-PREVYSLMVTCWNPNPSLRMSFDSICNDY
|| |||..|   . | ..||||.|.| ...|| .||  |.|.... . |.. | .   .| |..| ..|.|.|| .||. .|. | ||..| .  
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD-IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase AqueK325.AA Fer 349-617 29 9.6e-80 271.21 In-house 1-283 (283) Show / Hide
Range on Protein: 349-617
Range on HMM: 1-283/283
Sequence Identity: 29% (87 aa)

ITFDKEIGKGQFGTVFAG----TWYLAGGDRR---PVAIKRLSVQ-ASEEEKSKFLREGARMMQ-FFHPNVVKLLGVATVHTPFLLVQELMSKGDLKSYL
.|..| .|.| ||.|. |    . .....      .|. |..    |..|.. .|..|   |.. . ||||||. ||..   |...| |... |.|.|||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KGSRPQLDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLND-NLICK--IADFGMTRAA---NHVFDLN-KTEQIPLRWTAPEA
| .  .           . |  .....| ..|.||..|  || .|||.||||.|. . .. .|  |.|||| |.     .   .  | ...| ||.|||.
KKNKNK-----------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPET

FKLKDYSEKSDVYSYGMVLYEIWSLGRKPFPR------LYQN-QEIVDFIDQRGLLPPPP-GCPREVYSLMV-TCWNPNPSLRMSFDSICNDYL
.. . ||.|.||.|.| ...|| . | .|.|       . .   . .  | . |  .|.| ..| |....|  .||. .|. | ....||. . 
WQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK

Kinase AqueK325.AA InsR 349-619 36 1.6e-76 256.48 In-house 1-278 (278) Show / Hide
Range on Protein: 349-619
Range on HMM: 1-278/278
Sequence Identity: 36% (103 aa)

ITFDKEIGKGQFGTVFAG--TWYLAGGDRR--PVAIKRLSVQASEEEKSKFLREGARMMQFFHPNVVKLLGVATVHTPFLLVQELMSKGDLKSYLKGSRP
|.  .| |.| ||.|  |     ....  |  ..||| .  .|| .|.  || |   | .| . .||.|||| .   | . | |.| .||||||| . ||
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

QLDSNDPVPV--RDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTRAANHVFD-----LNKTEQIPLRWTAPEAFKLKD
    |.|.     .||...|..    .|..||  |  |.|||||||.|| . |. . .||.||||||.   ...     . .    | || |||  |   
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRD---IYEHDYYRKGGKGMLPVRWMAPESLKDGV

YSEKSDVYSYGMVLYEIWSLGRKPFPRLYQNQEIVDFI-DQRGLLPPPPGCPREVYSLMVTCWNPNPSLRMSFDSICNDYLKA
.. .|||.|.| ||.|. .||  |   |  | .. ..|   ...| || .||  .. ||  ||  .|..| .|  | ..||. 
FTTHSDVWSFGVVLWEMVTLGEQPYQGL-SNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDI-IHYLCD

Kinase AqueK325.AA Eph 349-616 38 4e-75 251.79 In-house 1-264 (264) Show / Hide
Range on Protein: 349-616
Range on HMM: 1-264/264
Sequence Identity: 38% (106 aa)

ITFDKEIGKGQFGTVFAGTWYLA-GGDRR---PVAIKRLSVQASEEEKSKFLREGARMMQFFHPNVVKLLGVATVHTPFLLVQELMSKGDLKSYLKGSRP
|. .| || |.|| |  |.  |  |       ||||| | . ..| ..  ||.| . | || |||...| || |   |   | | |  | | |.|.    
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

QLDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTRA------ANHVFDLNKTEQIPLRWTAPEAFKLKDY
|.            .. ||.   | |||||. |   |.|||||||||.|.| ||.||..|||..|       .. ..  .    ||.|||||||   . .
QF------------TVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKF

SEKSDVYSYGMVLYEIWSLGRKPFPRLYQNQEIVDFIDQRGLLPPPPGCPREVYSLMVTCWNPNPSLRMSFDSICNDY
.  ||| ||| |. |. | | .|.  .  ||...  |.|   ||||..||.  . ||  ||   .. |  |..| .  
TSASDVWSYGIVMWEVMSYGERPYWDM-SNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL

Kinase AqueK325.AA Src 349-616 33 1.6e-72 245.66 In-house 1-255 (255) Show / Hide
Range on Protein: 349-616
Range on HMM: 1-255/255
Sequence Identity: 33% (90 aa)

ITFDKEIGKGQFGTVFAGTWYLAGGDRRPVAIKRLSVQASEEEKSKFLREGARMMQFFHPNVVKLLGVATVHTPFLLVQELMSKGDLKSYLKGSRPQLDS
|.. ...|.|||| |. |.|     .. .||.| |.      .   ||.|   | .. |...|.|. | .   |.. |.|.||.| |  |||        
IKLCRKLGQGQFGEVWMGYWN----GNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-------

NDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTRAAN--H-VFDLNKTEQIPLRWTAPEAFKLKDYSEKSDVY
    .     . .||. .   .|.||  |  .|..|||||||||| ..|..||.||||  |       .    .   .| .||||||.    .. |||| 
---DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVW

SYGMVLYEIWSLGRKPFPRLYQNQEIVDFIDQRGLLPPPPGCPREVYS-LMVTCWNPNPSLRMSFDSICNDY
|.|  |.|| . || | |   .|.| .. ...   .| |..|| |.|  .|  ||.  |  |  |. ...  
SFGILLTEIVTYGRVPYPGM-TNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK325.AA Csk 349-616 37 4.5e-65 220.99 In-house 1-251 (251) Show / Hide
Range on Protein: 349-616
Range on HMM: 1-251/251
Sequence Identity: 37% (101 aa)

ITFDKEIGKGQFGTVFAGTWYLAGGDRRPVAIKRLSVQASEEEKSKFLREGARMMQFFHPNVVKLLGVATVHT-PFLLVQELMSKGDLKSYLKGSRPQLD
..  ..||.| || |  |. |.     | ||.| ..   . .   .|| | . | |  ||| |.|.||   .     .| | |||| |  ||  ||    
LHLGECIGHGEFGDVMQGE-YQN----RKVAVKCIKCD-GNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLR-SR----

SNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTRAANHVFDLNKTEQIPLRWTAPEAFKLKDYSEKSDVYSY
       | | . .|||||  |...||  |  |.||||||||||.|. . .. |. ||| .....   |   .  .|  ||||||.. | .| |||| |.
------GRHVITRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSF

GMVLYEIWSLGRKPFPRLYQNQEIVDFIDQRGLLPPPPGCPREVYSLMVTCWNPNPSLRMSFDSICNDY
|  | ||.| || |.||.   ...|  .       .| ||| .|| .|  ||. ||  | .|  .    
GILLWEIYSFGRVPYPRIPL-KDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL

Kinase AqueK325.AA Frk 349-617 35 7.6e-64 218.43 In-house 1-260 (260) Show / Hide
Range on Protein: 349-617
Range on HMM: 1-260/260
Sequence Identity: 35% (100 aa)

ITFDKEIGKGQFGTVFAGTWYLAGGDRRPVAIKRLSVQASEEEKSKFLREGARMMQFFHPNVVKLLGVATVHTPFLLVQELMSKGDLKSYLK-----GSR
| . ...| |||| |. | |  .     |||.|.|  ..   .   ||||   | .  || ...|  | ||  | ... ||| .| |. ||.     |..
IQLIRRLGSGQFGEVWEGLWNNT----TPVAVKTL--KPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ

PQLDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTR---AANH-VFDLNKTEQIPLRWTAPEAFKLKDYS
 |.              |||.     .|.||  |  .|..||||||||||.....||||||||. |     |  ...     ..|..|||||| . . ..
CQM--------------QQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFT

EKSDVYSYGMVLYEIWSLGRKPFPRLYQNQEIVDFIDQRGLLPPPPGCPREVYSLMVTCWNPNPSLRMSFDSI---CNDYL
 ||||.|.|..|.||   || |.| .  |.|... .|.   .| ||.|| ..|..|  ||. .|  |  |. .    .||.
IKSDVWSFGILLTEIITYGRMPYPGM-TNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF

Kinase AqueK325.AA TKL 355-612 22 3.5e-63 216.22 In-house 1-360 (364) Show / Hide
Range on Protein: 355-612
Range on HMM: 1-360/364
Sequence Identity: 22% (86 aa)

IGKGQFGTVFAGTWYLAGGDR------RPVAIKRLSVQASEEEKS-------------------------KFLREGARMMQFF-HPNVVKLLGVATVHTP
||.| ||.|. |.|   || .      ..||.|..... . |. .                         .|..| ..||  . |||.|...|...  ..
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------FLLVQELMSKGD-LKSYLKGSRPQLDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVT--------KNFVHRDLAARNVLLNDNLI-
             . .| |....|. |  ..                    ..|......|||.|| .| .        .. .||||  .|.|...|.  
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTN

-------------CKIADFGMTRAANHVFDLNKTE------------------QI-PLRWTAPEAFKLK----------------DYSEKSDVYSYGMVL
             |||.|||  |  .. .. |.|.                  |.  .|| |||... .                .||||.||||.|.||
VSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL

YEIWSLGRKPFPRLYQNQEIVD-------FIDQRGLLPPPPG--------------CPREVYSLMVTCWNPNPSLRMSFDSI
.|| .  | |.  .  ...|.         ..    |.||.               ||... .||  ||...|. | ||. |
WEILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI

Kinase AqueK325.AA S_TKc 349-625 23 3.3e-39 137.5 SMART 1-231 (231) Show / Hide
Range on Protein: 349-625
Range on HMM: 1-231/231
Sequence Identity: 23% (66 aa)

ITFDKEIGKGQFGTVFAGTWYLAGGDRRPVAIKRLSVQASEEEKSKFLREGARMMQFFHPNVVKLLGVATVHTPFLLVQELMSK--GDLKSYLKGSRPQ-
 .. ..|||| ||.|. ...     . | ||||...         ...|| . ...  |||.|||..|    . . .| |...   |||..|.|  ... 
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LDSNDPVPVRDVPSPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLICKIADFGMTRAANHVFDLNKTEQIPLRWTAPEAFKLKDYSE-
    .            .. .  .... |.... ..  ....||||   |.||..    ||.|||. |         .|    . . ||| .    |.  
LRFPF------------PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKC

KSDVYSYGMVLYEIWSLGRKPFPRLYQNQEIVDFIDQRGLLPPPPGCPREVYSLMVTCWNPNPSLRMSFDSICNDYLKANDDSLL
|.|..| | .|||  . |. |||   | |.. . |            ..|. ...  |.. .|. |..   . .| .... .  .
KCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK325.AA Pkinase 349-617 20 8.2e-33 117.11 Pfam 1-293 (293) Show / Hide
Range on Protein: 349-617
Range on HMM: 1-293/293
Sequence Identity: 20% (65 aa)

ITFDKEIGKGQFGTVFAGTWYLAGGDRRPVAIKRLSVQASEEEKSK-FLR--EGARMMQFFHPNVVKLLGVATVHTPFLLVQELMSKG----DLKSYLKG
... . ||.| ||.|. ...   |     ||.|.....  ...| .  .|  | . |  . |||.|.|... . ..   .|.|.. .|    ||..|...
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

SRPQLDSNDPVPVRDVP---SPQQLLKFCRDIASGMRHLVTKNFVHRDLAARNVLLNDNLIC----KIADFGMTRAA-NHVFDLNKTEQIPLRWTAPEAF
             |. .   |.... .... |..|. ..  ....||||   |.|...|  .    ||.|||  . . .     ..|    ... |||  
------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVI

K-LKDYSEKSDVYSYGMVLYEIWSLGRKPFP-R----LYQNQEIVDFIDQRGLLPPPPGCP---------------------REVYSLMVTCWNPNPSLR
.  ..|. |.|..|.| .|||  . || ||| .       .|  . . . .. |. .   .                     .|  ...  |....|. |
RGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

MSFDSICND-YL
 ... |... ..
PTAEQILQHPWF