AqueK331

Species: A.queenslandica
Alias: AqueK331
External Links:
Annotation:

Classification

Group: TK
Family: FAK

Sequence

Name Sequence Type Origin Length Description Download
AqueK331.AA Protein None 1145 None Fasta, JSON
AqueK331.kin_dom Protein Kinase Domain None 354 None Fasta, JSON

Protein domain

Protein domains of AqueK331.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK331.AA FAK 519-779 51 9.5e-144 483.86 In-house 1-285 (285) Show / Hide
Range on Protein: 519-779
Range on HMM: 1-285/285
Sequence Identity: 51% (147 aa)

IMLADRLGEGQFGDVHKGILYPDTT------------------------EEVAVAVKTCKPDSAPEERVKFLQEAAIMKQFNHPHIVKLFGVVTQGLRTY
| |   .||||||||..|.                              . ..||.|||| .  .... ||.||| ||||| ||||||| |...    . 
ITLNRCIGEGQFGDVYQGVYTNHKNGKGKNLAGNGKNSNSDQRNADSRPDKIQVAIKTCKKCCDDDNKEKFMQEAYIMKQFDHPHIVKLIGICEE-MPIW

IVMELAPLGQLRQYLLLNGESISQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEADFYVAS-RGKLPIKWMAPESIN
|.|||...| ||.||  | .| .   |. |  ||| ||  ||||..|||||||||.|  ||| .|| |||||||..  ..| ||  ||||||||.|||||
IIMELCKYGELRHYLQRNKNSLKHATLILYCYQLCMAMAYLESKKFVHRDIAARNVLVSSPDCVKLGDFGLSRWMHDHSYYKASPKGKLPIKWMSPESIN

FRRFTGSSDVWMFGVCCWEILMRGVKPFMSIKNDEVIGKLERGERLPLPPDCPPSLFNIMNHCWQYEPEERPSFTDIEQQLCVILE
|||||  ||||||||| ||||| |||||  .|| .|||..|.|||||.|| ||| |. .|  || |.| .|| |...  ||  |  
FRRFTTASDVWMFGVCMWEILMYGVKPFQWVKNNDVIGRIENGERLPMPPNCPPTLYSLMTRCWAYDPSKRPRFKELKCQLKDIYQ

Kinase AqueK331.AA Pkinase_Tyr 519-774 43 1.1e-124 422.89 Pfam 1-270 (270) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-270/270
Sequence Identity: 43% (118 aa)

IMLADRLGEGQFGDVHKGILY-PDTTEEVAVAVKTCKPDSAPEE--RVKFLQEAAIMKQF-NHPHIVKLFGVVT-QGLR--TYIVMELAPLGQLRQYLLL
| .   ||||.||.|.||...  .  ... ||||..|... .|.  | .|..||.||||. .||.||.| ||.| ||     |||||..|.| |. ||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---GESISQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEADFY--VASRGKLPIKWMAPESINFRRFTGSSDVWMF
.   .....   ||..  | ...| .|||||..|||.||||.|. .. ..| .||||.| ... | |  ... |||||||||||.||...||  ||||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVCCWEILMRGVKP-FMSIKNDEVIGKL-ERGERLPLPPDCPPSLFNIMNHCWQYEPEERPSFTDIEQQL
||..|||. .| .| .  ..| ||. .. |.|.|.| |..||. . ..| .||.|.||.||.|..| .||
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK331.AA TyrKc 519-774 39 7.1e-123 415.43 SMART 1-280 (280) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-280/280
Sequence Identity: 39% (115 aa)

IMLADRLGEGQFGDVHKGILYPDTTEEVAVAVKTCKPDSAPEERVKFLQEAAIMKQF--NHPHIVKLFGVVTQG-------LRTYIVMELAPLGQLRQYL
| | . ||||.|| |.||...      . ||||..|.|.    |  |..|| ||...  .||.||.|.||.||.          .||||..|.| |..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

LLNGESISQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEA-------DFYVAS---RGK--LPIKWMAPESINFRRF
  ... .. . ||..  | .. | .|.|||..|||.||||.|. ..  .| ||||||| ...        | |...    ||  |||.|||||.||...|
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TGSSDVWMFGVCCWEILMRGVKPFMS-----IKNDEVIGKLERGERLPLPPD--------CPPSLFNIMNHCWQYEPEERPSFTDIEQQL
|  ||||.||||.|||. .| .|        ..|.||| ....|.|.| ||.        ||. ...||  ||...||.||.|..| ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK331.AA TK 519-774 24 1.1e-110 372.38 In-house 1-486 (486) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-486/486
Sequence Identity: 24% (117 aa)

IMLADRLGEGQFG---DVHKGILYPD----------------------TTEEVAVAVKTCKPDSAPEERV-------------KFLQEAAIMKQFN----
| | . |||||||   .|.||.....                      . ... ||||..|...| ...              .||.||..||...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPHIVKLFGVVTQG------------LRTYIVMELAPLGQ----LRQYLLLNGE---------------------------------------------
 ||.||.|.||.|||               .||||..|.|     ||.||  . .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------SISQDILLN-------------------YIKQLCSAMVHLESK------NYVHRDIAARNILLLSPDK-----------IKLSDFG----
          ....  ||.                   .  |....| .|.||      |.||||.||||.|. . ..           .|..|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LSRWL-EEADFYVAS------------------------RGKLPIKWMAPESIN---------FRRFTGSSDVWMFGVCCWEILMRGVKPFMS-IK
    |.| . .. | |..|                        .|||||.|||||..|         ...||  ||||.|||..|||...| .|.   . 
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------DEVIGKLER------------GERLPLP--PDCP--------------PSLFNIMNHCWQYEPEERPSFTDIEQQL
|         .||. .|.|            |.|...|  |.||              . .. .|  ||.|.||.||.|... .||
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK331.AA UTK 519-774 35 1.4e-98 333.79 In-house 1-296 (296) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-296/296
Sequence Identity: 35% (104 aa)

IMLADRLGEGQFGDVHKGILYPDT--TEEVAVAVKTCKPDSA-PEERV---KFLQEAA---IMKQFN-HPHIVKLFGVVTQGLRTYIVMELAPLGQLRQY
..| ..||.|.||.|||. . ...   .|..||||.|..... . |.    .|. ||.   .||||. ||....| ||.||.  ..||.|... | ||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LLLNGESIS-------QDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSP-------DKIKLSDFG---LSRWLE---------EADFYVAS-RGK
|  ....          . .| .  .  ..| .|.|...||||.||||.|. .         ..|..|||   .|| .          |.. | |. ...
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPIKWMAPESINFR-RFTGSSDVWMFGVCCWEILMRGVKPFMSIKNDEVIGKLERG--ERLPLPPDCPPSLFNIMNHCWQYEPEERPSFTDIEQQL
.||.|||||... . ||| .|||| ||| ||||...| .|.  . |..|.  ...|   |.| |.||| .....|. ||.|.|.|||.| |..||.
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase AqueK331.AA SFK-Src 519-778 43 1.7e-92 274.36 In-house 1-259 (259) Show / Hide
Range on Protein: 519-778
Range on HMM: 1-259/259
Sequence Identity: 43% (115 aa)

IMLADRLGEGQFGDVHKGILYPDTTEEVAVAVKTCKPDSAPEERVKFLQEAAIMKQFNHPHIVKLFGVVTQGLRTYIVMELAPLGQLRQYLLL-NGESIS
| |  .||.|||||| ||    .|||   ||||| || .  .|   |||||..||.  ||  ..|. | | |   ||. ||   | |  ||   .|.|  
IRLEKKLGSGQFGDVWKGR-WNNTTE---VAVKTLKPGAMSAE--EFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLR

QDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEADF-YVASRG-KLPIKWMAPESINFRRFTGSSDVWMFGVCCWEILM
   |     |  . |  || .|.|||| ||||.|      .|  |||.|| |.. |  | |  | | |||| |||  |  ||   |||| ||.   ||  
MPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVT

RGVKPFMSIKNDEVIGKLER--GERLPLPPDCPPSLFNIMNHCWQYEPEERPSFTDIEQQLCVIL
 | .|.    | ||. ...|  |.|.| || ||. ...||  ||| ||..|| |     |.    
YGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF

Kinase AqueK331.AA Ack 519-774 38 1.7e-91 308.9 In-house 1-266 (266) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-266/266
Sequence Identity: 38% (104 aa)

IMLADRLGEGQFGDVHKGILYPDTTEEVAVAVKTCKPD--SAPEERVKFLQEAAIMKQFNHPHIVKLFGVVT-QGLRTYIVMELAPLGQLRQYLLLNGES
| |   ||.| || |..|       . . ||||  ..|  ..|..   ||.|.||| . .|||.|.|.|||  | .    |.||||.| |   |   . .
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPM-LMMVTELAPCGSLLDCLRK-HCR

ISQD---ILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPD-KIKLSDFGLSRWLEEADF-YVASRGK---LPIKWMAPESINFRRFTGSSDVWMFG
 .     .|...  |....|  ||.|. .||| ||||||| |.| |.| .||||.| | ...  |. .  .   .|. |.|||....|.|.  |||||||
TAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFG

VCCWEILMRGVKPFMSIKNDEVIGKLE-RGERLPLPPDCPPSLFNIMNHCWQYEPEERPSFTDIEQQL
|. ||    | .|.      ... |..  ||||| |..||. . ..|  ||| .|..||.| .|. ||
VTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL

Kinase AqueK331.AA Fer 519-775 36 8.9e-90 304.56 In-house 1-283 (283) Show / Hide
Range on Protein: 519-775
Range on HMM: 1-283/283
Sequence Identity: 36% (102 aa)

IMLADRLGEGQFGDVHKG----ILYPDTTEEV---AVAVKTCKPDSAPEE-RVKFLQEAAIMKQ-FNHPHIVKLFGVVTQGLRTYIVMELAPLGQLRQYL
. | . |||| ||.|.||     .. ... .|   ||.||.|| ..| .| . .|..|| ||.. ..||..||..|| ..    .||||... | |. ||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

LLNGE-SISQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLS-PDKIK--LSDFGLSRW--LEEADFYVA-SRGKLPIKWMAPESINFRRFTGSSD
  |.. ..| . ..... | .. | .|.||| .||||||||.|.    .|.|  .||||.||    .. | . .    |.||.|.|||..... ..  .|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWMFGVCCWEILMRGVKPFMS----IKNDEV----IGKLER-GERLPLPPDCPPSLFNIMN-HCWQYEPEERPSFTDIEQQLC
|| ||| |||| ..| .|..     .|. .|    . . .. | ..|.|. .|| . .||  .|||..||.||....| |.| 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK

Kinase AqueK331.AA Eph 519-774 41 4.4e-88 295.97 In-house 1-264 (264) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-264/264
Sequence Identity: 41% (109 aa)

IMLADRLGEGQFGDVHKGILYPD-TTEEV---AVAVKTCKPDSAPEERVKFLQEAAIMKQFNHPHIVKLFGVVTQGLRTYIVMELAPLGQLRQYLLLNGE
|..   .|.|.||.| .| | .   ..||   .||.|| |  ..  .|. || ||.|| ||.||.|..| ||||..    || |   .| | ..|  . .
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

SISQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEAD----FYVASRGKLPIKWMAPESINFRRFTGSSDVWMFGVCC
 ..   |.  .. . |.|  | . |||||| ||||||. |    | ||||||| ||. .     |  . || ||.| ||| | .|.|| .|||| .|.  
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVM

WEILMRGVKPFMSIKNDEVIGKLERGERLPLPPDCPPSLFNIMNHCWQYEPEERPSFTDIEQQL
||..  | .|.    | .||   | | ||| |.|||..|. .| .|||.....|| |..|   |
WEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL

Kinase AqueK331.AA Syk 519-768 37 8.1e-84 284.77 In-house 1-257 (257) Show / Hide
Range on Protein: 519-768
Range on HMM: 1-257/257
Sequence Identity: 37% (96 aa)

IMLADRLGEGQFGDVHKGILYPD----TTEEVAVAVKTCK-PDSAPEERVKFLQEAAIMKQFNHPHIVKLFGVVTQGLRTYIVMELAPLGQLRQYLLLNG
. . . .| | || |||| .           . ||.|. |   . | .   |. || .| |  ||.||.. | . ..     |||.|.|| . .||. ..
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKADHNQPADKQEFMREAQVMCQLDHPCIVRMIG-ICHAEMMMMVMEMAELGPMHKYLQQHR

ESISQDILLNYIK-QLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWL-EEADFYVA-SRGKLPIKWMAPESINFRRFTGSSDVWMFGVCC
..|.    |  .  |  . |  ||.|. |||| ||||.||      | ||||.|. |    . |.| . || |.|| |||.|... |  .|||| |||  
HEITANNVLELWHTQVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTM

WEILMRGVKPFMSIKNDEVIGKLERGERLPLPPDCPPSLFNIMNHCWQYEPEERPSFT
|| . .| ||  ..|. ||.  .| |.|.. |. ||. .  .|| || |... || | 
WEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV

Kinase AqueK331.AA Src 519-774 42 1.7e-82 280.1 In-house 1-255 (255) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-255/255
Sequence Identity: 42% (111 aa)

IMLADRLGEGQFGDVHKGILYPDTTEEVAVAVKTCKPDSAPEERVKFLQEAAIMKQFNHPHIVKLFGVVTQGLRTYIVMELAPLGQLRQYLL--LNGESI
| | ..||.||||.| .|.       .. ||||| ||..   .   ||||| |||.. |...|.|. |..|.   ||| |.   | | .||     | ..
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL

SQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEA-DFYVASRG-KLPIKWMAPESINFRRFTGSSDVWMFGVCCWEIL
.  .|.    |  . |  |||.||.||| ||||.|       |  |||| | ..|  | |.|. | |.||||.||| ||..|||  |||| ||.  .|| 
HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIV

MRGVKPFMSIKNDEVIGKLERGERLPLPPDCPPSLFN-IMNHCWQYEPEERPSFTDIEQQL
 .|  |    .| ||. ..||| |.| |. ||..|.. || .||. .||.|| |  . . |
TYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK331.AA TK-Unique 519-774 33 3.9e-81 275.87 In-house 1-294 (294) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-294/294
Sequence Identity: 33% (98 aa)

IMLADRLGEGQFGDVHKGILYPDT---TEEVAVAVKTCKPDSAPEERVKFLQEAAIMKQFN-HPHIVKLFGVVTQGL-RTYIVMELAPLGQLRQYLLLNG
. . |..|||.|| |..| . ...    . . ||||..| .. .... .||.|...||.   ||.||...|. |    ...|.|| .| | |. ||  ..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-------------------------ESISQDILLNYIKQLCSAMVHLES--KNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEADFYVASR--GKLPI
                         |.||   |.....|....| .|.|  |. ||||..|||.|| .  ..|..|||..| ..    |. ..  |..||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWMAPESIN--FRRF-TGSSDVWMFGVCCWEILMRGVKPFMSIKNDEVIGKLERGERLPLPPDC-PPSLFNIMNHCWQYEPEERPSFTDIEQQL
.||||||.    . . |  ||||.|||  |||.  |  |. ........ ....| |.|.|. | .. ..|.|  |||.||||||||..| ..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase AqueK331.AA S_TKc 519-776 25 1.1e-49 172.33 SMART 1-231 (231) Show / Hide
Range on Protein: 519-776
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

IMLADRLGEGQFGDVHKGILYPDTTEEVAVAVKTCKPDSAPEERVKFLQEAAIMKQFNHPHIVKLFGVVTQGLRTYIVMELAPL--GQLRQYLLLNGES-
  . . .|.| || |.|..          ||.|  |         ....| .|.|. .||.||||..|     . |.|||...   | |..|.  .|   
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----ISQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKIKLSDFGLSRWLEEADFYVASRGKLPIKWMAPESINFRRFTG-SSDVWMFGVCC
    ..      |..|.|.|. .. |.. .|||.   |||| .   ||..||||.| |        .       .|||| .    ... ..|.| .|.. 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

WEILMRGVKPFMSIKNDEVIGKLERGERLPLPPDCPPSLFNIMNHCWQYEPEERPSFTDIEQ-------QLCV
.| |  |  ||    ..... |. .          .|.. .....|.|..||.||.  .. |          .
YEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK331.AA Pkinase 519-774 22 1.5e-34 123.26 Pfam 1-293 (293) Show / Hide
Range on Protein: 519-774
Range on HMM: 1-293/293
Sequence Identity: 22% (68 aa)

IMLADRLGEGQFGDVHKGILYPDTTEEVAVAVKTCKPDSAPE--ERVKFL-QEAAIMKQFNHPHIVKLFGVVTQGLRTYIVMELAPLG----QLRQYLL-
. .  ..|.| || | |..   .      ||||. | ... .  .. ... .|..||| .|||.||.|..... . . |.|||... |     |  |.  
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

LNGESI--SQDILLNYIKQLCSAMVHLESKNYVHRDIAARNILLLSPDKI----KLSDFGLSRWL----EEADFYVASRGKLPIKWMAPESIN-FRRFTG
 .. ..  | . . .|..|..... .. |.. .|||.   |||. . . |    |..||||.. .    . .. .. ...     .|||| |.  .  . 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPW-----YMAPEVIRGGQYYGP

SSDVWMFGVCCWEILMRGVKPFMSI----KNDEVIGKLERGERLPLPPDCP-----------------------PSLFNIMNHCWQYEPEERPSFTDIEQ
..|.| .|. ..| |  |  || .     . .. . ...|  . ||. |.|                       ...  ... |... |..||....| |
KVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

Q--L
   .
HPWF

Focal_AT AqueK331.AA Focal_AT 1023-1138 37 2.4e-29 105.64 Pfam 14-129 (139) Show / Hide
Range on Protein: 1023-1138
Range on HMM: 14-129/139
Sequence Identity: 37% (44 aa)

CTTGVVQSIVELSTKLPAARPGDYVDLVKGVGVSLRQLLVKVDSSLDMIPEHTHSKVKMAHKVLSSDMTQLVKSMKELQENYQSFLLDHYQKQMLQSANI
....|| |..|.. |. .. . .||..|| ||..||.|| .||  .   |  .|  . ||||||..||  |.  |.  | .    |   ..||||. | .
NVMQVVKSVMEMKNKVHKLPSEEYVNMVKNVGLELRKLLQSVDEIYPSLPAQCHREIEMAHKVLNKDMHELISKMRLAQQYAMTTLDQECKKQMLTAAHV

IAVNSKHLLEAFSQAR
 |.  | || |  |||
LAMDAKNLLDAVDQAR