Gene AqueK339 (A.queenslandica)

AqueK339

Species: A.queenslandica
Alias: AqueK339
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK339.AA Protein None 445 None Fasta, JSON
AqueK339.kin_dom Protein Kinase Domain None 86 None Fasta, JSON

Protein domain

Protein domains of AqueK339.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SRCR AqueK339.AA SRCR 133-192 42 1.6e-16 57.3 Pfam 1-77 (112) Show / Hide 
Range on Protein: 133-192
Range on HMM: 1-77/112
Sequence Identity: 42% (33 aa)

VNGSHDWEGRVELCV-SGSWGTVCDN-W-WNSPDAAVVCGQLG--WGTSGTAISSAY--FG---------QDNV-CT
|.||.  |||||..   |.||||||.   |.  || ||| |||  .| . .  ..||  ||          ||| |.
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCH
SR AqueK339.AA SR 130-193 33 4e-08 25.67 SMART 1-103 (118) Show / Hide 
Range on Protein: 130-193
Range on HMM: 1-103/118
Sequence Identity: 33% (34 aa)

IRIVNGSHDWEGRVELCVSG----SWGTVCDNWWNSPDAAVVCGQLGWGTSGTAIS-----SAYFGQ-------DNV-----------------------
.| |.|..  |||||   .|    .||||||. |.  || ||| ||| |.  .| .     .|.|||       |||                       
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CTP
|  
CSH
SR AqueK339.AA SR 196-293 46 6.4e-49 169.75 SMART 1-118 (118) Show / Hide 
Range on Protein: 196-293
Range on HMM: 1-118/118
Sequence Identity: 46% (55 aa)

VRLVNGSNSIEGRVELCHNG----RWGAVCDDSWDNTDASVVCRQLGYDSGTAFG------SAYFGQGTVSIIMNDVHCNGTEFYLTNCTH--TMNHS--
||||.|.|. |||||  |||    .|| ||||.|| .||.|||||||. .. .        .|.||||.  | | .|.|.|||  |..|.|    .|.  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CNH------SQDAGVRCS
|.|      ..||||.||
CSHNHHRNRQEDAGVVCS
SRCR AqueK339.AA SRCR 199-293 46 8.8e-45 152.24 Pfam 1-112 (112) Show / Hide 
Range on Protein: 199-293
Range on HMM: 1-112/112
Sequence Identity: 46% (52 aa)

VNGSNSIEGRVELCH-NGRWGAVCDD-S-WDNTDASVVCRQLGYDSG---TAFGSAY--FG--QGTVSIIMNDVHCNGTEFYLTNC--THTMN--HS--C
|.||.. |||||... ||.||.|||| . ||..||.|||||||. .|   . ...||  ||  .||  | |..|.|.|.|  |..|  ... .  |.  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

NHS-QDAGVRCS
.|| .||||.||
SHSREDAGVICS
Kinase AqueK339.AA TK 321-433 23 5.8e-41 134.55 In-house 243-463 (486) Show / Hide 
Range on Protein: 321-433
Range on HMM: 243-463/486
Sequence Identity: 23% (51 aa)

VANGMSYLASQ------RFIHCDLAARNCMIDGDGI-----------IKLKDSS----------------------------------------------
.|.||.||.|.      .|.| |||||||... ...           .|. |                                                
IACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQ

STIKLPVKWMVIESIHDGL---------YSEKSDVWSYGVFCWEVFSLGRLPYPGLDPV----------GVVELLDAGGR------------LQNPNNEA
|  |||..||  |.. |.          ...||||||.||..||.|..|. ||.|  .            |.|.| .|||            .. |  . 
SGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPH

CS--------------QEMYD
|.              .|.||
CPDWMRYRMHPPHCPPEEYYD
Kinase AqueK339.AA TK-Unique 321-432 36 6.5e-38 128.35 In-house 140-270 (294) Show / Hide 
Range on Protein: 321-432
Range on HMM: 140-270/294
Sequence Identity: 36% (49 aa)

VANGMSYLAS--QRFIHCDLAARNCMIDGDGIIKLKDSSSTI---------------KLPVKWMVIESIH--DGLY-SEKSDVWSYGVFCWEVFSLGRLP
.|.||.||||  ....| ||.|||... .|...|. |   .                ..|..||  ||.   .| | ..||||||.||. ||.|.||  |
IACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACP

YPGLDPVGVVELLDAGGRLQNPNNEAC-SQEMY
|||...  ..|.. .| |.. |..  | |.|||
YPGMPWKDIMECIRDGYRMPQPEH--CCSHEMY
Kinase AqueK339.AA Tec 318-433 41 4.6e-30 102.27 In-house 103-229 (254) Show / Hide 
Range on Protein: 318-433
Range on HMM: 103-229/254
Sequence Identity: 41% (53 aa)

TLKVANGMSYLASQRFIHCDLAARNCMIDGDGIIKLKD-------------SSSTIKLPVKWMVIESIHDGLYSEKSDVWSYGVFCWEVFSLGRLPYPGL
.. |  || || .. ||| ||||||| .. ....|  |             ||.  | ||||   |  |   || |||||..||  |||||.|. ||. .
CQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENM

DPVGVVELLDAGGRLQNPNNEACSQEMYD
. . |||    | ||  |  . ||...|.
SNSEVVEHVSQGHRLYRP--HLCSMHIYQ
Kinase AqueK339.AA Pkinase_Tyr 361-433 46 1.6e-28 97.24 Pfam 175-247 (270) Show / Hide 
Range on Protein: 361-433
Range on HMM: 175-247/270
Sequence Identity: 46% (35 aa)

KLPVKWMVIESIHDGLYSEKSDVWSYGVFCWEVFSLGRLP-YPGLDPVGVVELL-DAGGRLQNPNNEACSQEMYD
|||.|||  |.|..| ...||||||.|| .||.|..|. | |||...  |.|.. . |.|.  | |  |..|.||
KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYD
Kinase AqueK339.AA KIN6 361-433 42 4.9e-26 82.87 In-house 210-282 (305) Show / Hide 
Range on Protein: 361-433
Range on HMM: 210-282/305
Sequence Identity: 42% (32 aa)

K-LPVKWMVIESIHDGLYSEKSDVWSYGVFCWEVFSLGRLPYPGLD-PVGVVELLDAGGRLQNPNNEACSQEMYD
. ||.|||  |..    .| ||||||.||  .|.||||  |||..  |. . | . .|.|.. | .  |. | ||
RYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYD
Kinase AqueK339.AA UTK 361-433 39 2.1e-25 83.86 In-house 200-273 (296) Show / Hide 
Range on Protein: 361-433
Range on HMM: 200-273/296
Sequence Identity: 39% (29 aa)

KLPVKWMVIESIHDG-LYSEKSDVWSYGVFCWEVFSLGRLPYPGLDPVGVVELLDAGGRLQNPNNEACSQEMYD
..|..||  |.. ..  ...||||||.||.|||... |||||||.  . |.. . .|||.. | ...|. ..|.
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYR
Kinase AqueK339.AA ALK 362-424 52 5.1e-24 79.82 In-house 179-241 (273) Show / Hide 
Range on Protein: 362-424
Range on HMM: 179-241/273
Sequence Identity: 52% (33 aa)

LPVKWMVIESIHDGLYSEKSDVWSYGVFCWEVFSLGRLPYPGLDPVGVVELLDAGGRLQNPNN
.|||||  |   ||..  |.||||.|| |||.||||. ||||     | |.. .|||.  | |
MPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN
Kinase AqueK339.AA HMTK 360-433 35 1.3e-22 75.69 In-house 192-269 (291) Show / Hide 
Range on Protein: 360-433
Range on HMM: 192-269/291
Sequence Identity: 35% (28 aa)

IKLPVKWMVIESIH--DGLYSEKSDVWSYGVFCWEVFSLGRLPYP--GLDPVGVVELLDAGGRLQNPNNEACSQEMYD
.|||.||| .|     ..  |||||||..||..||... |..||.  ..    |   . .|.||  |.  .|. ...|
VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWD
Kinase AqueK339.AA VEGFR 361-406 63 6e-21 75.87 In-house 238-283 (332) Show / Hide 
Range on Protein: 361-406
Range on HMM: 238-283/332
Sequence Identity: 63% (29 aa)

KLPVKWMVIESIHDGLYSEKSDVWSYGVFCWEVFSLGRLPYPGLDP
.|| ||| .||| |  |. .||||||||| ||.||||  |||| ..
RLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQI
Kinase AqueK339.AA FGFR 362-432 44 1e-20 67.31 In-house 200-269 (293) Show / Hide 
Range on Protein: 362-432
Range on HMM: 200-269/293
Sequence Identity: 44% (32 aa)

LPVKWMVIESIHDGLYSEKSDVWSYGVFCWEVFSLGRLPYPGLD-PVGVVELLDAGGRLQNPNNEACSQEMY
||.|||  |.  |  |  .||||||||  ||.. .|  |||.        ..|  | |.  | |  ||||.|
LPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIY
Kinase AqueK339.AA Met 321-352 59 4.8e-17 52.16 In-house 113-144 (271) Show / Hide 
Range on Protein: 321-352
Range on HMM: 113-144/271
Sequence Identity: 59% (19 aa)

VANGMSYLASQRFIHCDLAARNCMIDGDGIIK
|| ||.|.|||.|.| |||.||||.| . ..|
VAKGMMYMASQKFVHRDLACRNCMLDEHFTVK
Kinase AqueK339.AA TyrKc 293-442 22 1e-15 31.46 SMART 9-280 (280) Show / Hide 
Range on Protein: 293-442
Range on HMM: 9-280/280
Sequence Identity: 22% (62 aa)

SCEFGIVYRGVTKIENQMSQAVAVKTLK------------------------------------------------------------------------
...||.||.|. |      . ||||.||                                                                        
EGAFGEVYKGTWK------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDL

------VANGMSYLASQRFIHCDLAARNCMIDGDGIIK---------LKDS------SSTIK----------LPVKWMVIESIHDGLYSEKSDVWSYGVF
      .|.||.||.|...|| |||||||... ....|         ..|       .....          ||..|| .|.| .| ...||||||.|| 
LSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVC

CWEVFSLGRLPYPG-----LDPVGVVELLDAGGRLQNPNNEA------CSQEMYD--------------NAHNLTIIV
.||.|..|  ||||     ...  |.|....|.|.  | |        |..|||.              .  ..  . 
MWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK339.AA Met 361-422 36 1.6e-15 47.06 In-house 171-244 (271) Show / Hide 
Range on Protein: 361-422
Range on HMM: 171-244/271
Sequence Identity: 36% (27 aa)

KLPVKWMVIESIH--------DGL-YSEKSDVWSYGVFCWEVFSLGRLPYPGLDP-VGVVELLDAG--GRLQNP
.||||||  |.          .   .. |||||| ||  || .  |  |||  |. . .   |  |   ||  |
RLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQP
Kinase AqueK339.AA Pkinase_Tyr 321-352 50 3e-14 48.86 Pfam 120-151 (270) Show / Hide 
Range on Protein: 321-352
Range on HMM: 120-151/270
Sequence Identity: 50% (16 aa)

VANGMSYLASQRFIHCDLAARNCMIDGDGIIK
.|.||.||.|...|| |||||||... ....|
IAKGMEYLESKNCIHRDLAARNCLVTENNVVK
Kinase AqueK339.AA UTK 319-353 38 1.9e-13 42.34 In-house 125-166 (296) Show / Hide 
Range on Protein: 319-353
Range on HMM: 125-166/296
Sequence Identity: 38% (16 aa)

LKVANGMSYLASQRFIHCDLAARNCMIDGDG-------IIKL
. .|.||.||.|..|.|.||||||| .. ..       ..|.
WDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKI
Kinase AqueK339.AA HMTK 321-345 64 5.1e-12 38.29 In-house 137-161 (291) Show / Hide 
Range on Protein: 321-345
Range on HMM: 137-161/291
Sequence Identity: 64% (16 aa)

VANGMSYLASQRFIHCDLAARNCMI
.| ||.|.||||..| |||||||..
CASGMAYIASQRMVHMDLAARNCLV
Kinase AqueK339.AA FGFR 321-355 54 7.5e-10 29.71 In-house 145-179 (293) Show / Hide 
Range on Protein: 321-355
Range on HMM: 145-179/293
Sequence Identity: 54% (19 aa)

VANGMSYLASQRFIHCDLAARNCMIDGDGIIKLKD
|| || ||||.. || ||||||  .  | ..|  |
VARGMEYLASRKCIHRDLAARNVLVTDDYVMKICD
Kinase AqueK339.AA KIN6 321-346 50 2.2e-09 26.95 In-house 153-178 (305) Show / Hide 
Range on Protein: 321-346
Range on HMM: 153-178/305
Sequence Identity: 50% (13 aa)

VANGMSYLASQRFIHCDLAARNCMID
...||.||.| ..|| ||||||  ..
ICDGMEYLHSKNCIHRDLAARNVLVT
Kinase AqueK339.AA VEGFR 321-352 50 4.4e-09 30.59 In-house 182-213 (332) Show / Hide 
Range on Protein: 321-352
Range on HMM: 182-213/332
Sequence Identity: 50% (16 aa)

VANGMSYLASQRFIHCDLAARNCMIDGDGIIK
||.|| .|||.  || ||||||  .. . ..|
VARGMEFLASRKCIHRDLAARNILLCENNVVK
Kinase AqueK339.AA ALK 321-343 60 3e-06 17.43 In-house 120-142 (273) Show / Hide 
Range on Protein: 321-343
Range on HMM: 120-142/273
Sequence Identity: 60% (14 aa)

VANGMSYLASQRFIHCDLAARNC
|| |  || ...||| | |||||
VAQGCHYLEENHFIHRDIAARNC
S_TKc AqueK339.AA S_TKc 207-441 15 3.3e-05 -100.5 SMART 13-231 (231) Show / Hide 
Range on Protein: 207-441
Range on HMM: 13-231/231
Sequence Identity: 15% (41 aa)

GRVELCHNGRWGAVCDDSWDNTDASVVCRQLGYDSGTAFGSAYFGQGTVSIIMNDVHCNGTEFYLTNCTHTMNHSCNHSQDAGVR--CSCEFGIVYRGVT
|.| .|.. .           |.  | . ..              .  ..| ..  | |   .| .  .    ..     .       .    |. ||  
GKVYKCRHKK-----------TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRH

KIENQMSQAVAVKTLK-VANGMSYLASQRFIHCDLAARNCMIDGDGIIKL------KDSSSTIKLPVKWMVIESIHDGLYSE-KSDVWSYGVFCWEVFSL
.   ...  .| . .. ..... |. |...||.||   | ..|    ||.      .   .|.     .|  | .    |.  |.|.|| |.  .| .. 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-

GRLPYPGLDPVGVVELLDAGGRLQNPNNEACSQEMY---------D-------NAHN-------LTII
|. |.|      . ....  |          |.|.          |        | .          .
GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK339.AA Pkinase 377-403 44 0.002405 12.91 Pfam 189-214 (293) Show / Hide 
Range on Protein: 377-403
Range on HMM: 189-214/293
Sequence Identity: 44% (12 aa)

YSEKSDVWSYGVFCWEVFSLGRLPYPG
|. |.|.||.|. ..|... ||.|.||
YGPKVDMWSCGCILYEMLC-GRPPFPG
Kinase AqueK339.AA Pkinase_Tyr 293-320 41 0.026034 8.45 Pfam 9-37 (270) Show / Hide 
Range on Protein: 293-320
Range on HMM: 9-37/270
Sequence Identity: 41% (12 aa)

SCEFGIVYRGVTK-IENQMSQAVAVKTLK
. .|| ||.|. |  . .  . ||||.||
EGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Kinase AqueK339.AA Met 296-320 32 0.03432 2.65 In-house 11-35 (271) Show / Hide 
Range on Protein: 296-320
Range on HMM: 11-35/271
Sequence Identity: 32% (8 aa)

FGIVYRGVTKIENQMSQAVAVKTLK
|| ||.|    . .    .|.|.|.
FGCVYHGMYHDNDGNEHHCACKSLH
Kinase AqueK339.AA TK-Unique 292-320 37 0.061733 2.61 In-house 8-39 (294) Show / Hide 
Range on Protein: 292-320
Range on HMM: 8-39/294
Sequence Identity: 37% (12 aa)

CSCEFGIVYRGVTKI--ENQMSQ-AVAVKTLK
....|| |.||  .   ...  |  ||||.||
GEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK
Kinase AqueK339.AA TK 295-320 23 0.103204 0.65 In-house 11-61 (486) Show / Hide 
Range on Protein: 295-320
Range on HMM: 11-61/486
Sequence Identity: 23% (12 aa)

EFG---IVYRGVTKIEN----------------------QMSQAVAVKTLK
.||    ||.|  . .|                      .  . ||||.||
QFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLK
Kinase AqueK339.AA Pkinase 321-353 35 0.174631 6.33 Pfam 117-153 (293) Show / Hide 
Range on Protein: 321-353
Range on HMM: 117-153/293
Sequence Identity: 35% (13 aa)

VANGMSYLASQRFIHCDLAARNCMIDGDGII----KL
.. |. |. |...||.||   |..|| .| |    |.
ILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKI