AqueK342

Species: A.queenslandica
Alias: AqueK342
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK342.AA Protein None 417 None Fasta, JSON
AqueK342.kin_dom Protein Kinase Domain None 93 None Fasta, JSON

Protein domain

Protein domains of AqueK342.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK342.AA SR 23-165 33 4.8e-43 150.23 SMART 1-118 (118) Show / Hide
Range on Protein: 23-165
Range on HMM: 1-118/118
Sequence Identity: 33% (53 aa)

LQLVNGDVPEQGRVEICING----TWGTVCDDHWNHSNAQVVCRQLGYLNAGTPDQGRVEICINGTWGTVCDDDWNHSNAQVVCRQLGYLNAVPEYYS--
. ||.|. | .||||. .||    .|||||||.|                                         .  .|.|||||||. .||  . .  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNW-----------------------------------------DIRDANVVCRQLGCGGAVSASQTLP

--RAYFGAGTGKIFLDDVRCAGNESSLLECMHNPIGSHN--CDH------SKDVGVSCI
  .|.||.|.| | .|.||| |.|.|| .|.|...|.||  |.|      . |.|| | 
ATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNCCSHNHHRNRQEDAGVVCS

SRCR AqueK342.AA SRCR 74-165 51 1e-42 145.28 Pfam 8-112 (112) Show / Hide
Range on Protein: 74-165
Range on HMM: 8-112/112
Sequence Identity: 51% (54 aa)

QGRVEICI-NGTWGTVCDD-D-WNHSNAQVVCRQLGY-LNAVPEYYSRAY--FG--AGTGKIFLDDVRCAGNESSLLECMHNPIGS--HN--CDHS-KDV
.||||..  ||.||||||| . |.  .|.|||||||.  .||  . ..||  ||  .||| | .|.||| |||.|| .| | | |   ||  |.||  |.
EGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMCSHSREDA

GVSCI
|| | 
GVICS

SRCR AqueK342.AA SRCR 26-69 54 1.2e-20 71.21 Pfam 1-48 (112) Show / Hide
Range on Protein: 26-69
Range on HMM: 1-48/112
Sequence Identity: 54% (26 aa)

VNGDVPEQGRVEICI-NGTWGTVCDD-H-WNHSNAQVVCRQLGY-LNA
|.|..| .||||..  ||.||||||| . |.  .|.|||||||.  .|
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGA

Kinase AqueK342.AA Pkinase_Tyr 305-400 48 5.7e-48 163.08 Pfam 175-270 (270) Show / Hide
Range on Protein: 305-400
Range on HMM: 175-270/270
Sequence Identity: 48% (48 aa)

KLPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTP-YPGLDPSGLVELL-DNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
||||||||.|.|..|.|..||||||.|||.||.|..|..| |||.... ..|.. ..|.|. .|.|   ..||| || .|||.  ..|| |||..|  
KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

SR AqueK342.AA SR 172-275 40 3.3e-44 154.11 SMART 1-118 (118) Show / Hide
Range on Protein: 172-275
Range on HMM: 1-118/118
Sequence Identity: 40% (48 aa)

LRLVNGSTPVEGRVEICITY----MWGTVCDDLWTNVNAEVVCTQLGYPTTGAVYRH----MAYFGEGRGTIYLDDVKCNGSESSLLSCSHLSSDDHS-V
.|||.|..| |||||. .       ||||||| |.  .|.||| |||...  ....      |.||.|.| |..|.| |.|.|.||  |.| .   |. .
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

DCYH------HEDVGVICN
 | |      .||.||.|.
-CSHNHHRNRQEDAGVVCS

Kinase AqueK342.AA TK 305-400 33 8e-44 144.32 In-house 346-486 (486) Show / Hide
Range on Protein: 305-400
Range on HMM: 346-486/486
Sequence Identity: 33% (47 aa)

KLPIKWMALESIHDGV---------FSEKSDVWSYGVLCWEVFSLGKTPYPG-LDP---------SGLVELLDNGGR------------LQPPQ-NGASS
||||.||| |.. |.|         |..||||||.|||.||.|..|..||.| ..            ..|.| .|||            ...||  ....
KLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPD

-------------QEIYALMVSCWHESSSNRPLFSELVESV
             .|.| || .|||.  . || ||.|.|  
WMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK342.AA FGFR 306-400 47 1.5e-42 142.79 In-house 200-293 (293) Show / Hide
Range on Protein: 306-400
Range on HMM: 200-293/293
Sequence Identity: 47% (46 aa)

LPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLD-PSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
|||||||.|.  | |.  .||||||||| ||.. .| .|||.      | ..|  | |. .|.|   ||||| .| .|||.... || | .|||. 
LPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQLVEYL

SRCR AqueK342.AA SRCR 175-275 43 9.3e-40 135.36 Pfam 1-112 (112) Show / Hide
Range on Protein: 175-275
Range on HMM: 1-112/112
Sequence Identity: 43% (49 aa)

VNGSTPVEGRVEICI-TYMWGTVCDD-L-WTNVNAEVVCTQLGY-PTTGAVYRHMAY--FG--EGRGTIYLDDVKCNGSESSLLSCSHLSSDDHSVD--C
|.||.| |||||..     |||||||   |.. .|.||| |||. ..   .. . ||  ||  .|.| |..|.| |.|.|.|| .|.| .. .|. .  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

YHH-EDVGVICN
 |. ||.||||.
SHSREDAGVICS

Kinase AqueK342.AA VEGFR 305-400 50 4.4e-39 136.16 In-house 238-332 (332) Show / Hide
Range on Protein: 305-400
Range on HMM: 238-332/332
Sequence Identity: 50% (49 aa)

KLPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLD-PSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
.|||||||.||| | |.. .||||||||. ||.||||. |||| .    .   | .| |.  |    . .|||  | .|||.    ||.||||||  
RLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPD--YCTPEIYHIMLDCWHKEPEERPHFSELVEHL

Kinase AqueK342.AA TK-Unique 305-400 41 6.8e-39 131.77 In-house 197-294 (294) Show / Hide
Range on Protein: 305-400
Range on HMM: 197-294/294
Sequence Identity: 41% (41 aa)

KLPIKWMALESIH--DGVF-SEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGAS-SQEIYALMVSCWHESSSNRPLFSELVESV
..||.|||.||.   .|.. ..||||||.||| ||.|.||..||||.... ..|.. .| |.. |..  . |.|.| || |||... . || |....   
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL





Kinase AqueK342.AA UTK 305-400 40 4.4e-38 127.86 In-house 200-296 (296) Show / Hide
Range on Protein: 305-400
Range on HMM: 200-296/296
Sequence Identity: 40% (39 aa)

KLPIKWMALESIHDG-VFSEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
..||.||| |.. ..  |..||||||.||.|||... |..||||.    ... . ||||...|.. . . ..| ||..||| . ..|| | .||. .
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase AqueK342.AA KIN6 305-400 44 4.8e-38 123.19 In-house 210-305 (305) Show / Hide
Range on Protein: 305-400
Range on HMM: 210-305/305
Sequence Identity: 44% (44 aa)

K-LPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLD-PSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
. |||||||.|..    || ||||||.||| .|.||||  |||..  |  . | .  |.|.. | .   . |||  | ||| | .. || |.|.    
RYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF

Kinase AqueK342.AA EGFR 305-401 44 2.8e-36 117.82 In-house 164-258 (258) Show / Hide
Range on Protein: 305-401
Range on HMM: 164-258/258
Sequence Identity: 44% (43 aa)

KLPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESVN
|.||||||||.|| ...  .|||||||| |||.   |. || |.  .   .||..| ||. |..   .. .| .||.||.  .  || | ||.|  .
KMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPI--CTIDVYMVMVKCWMIDEDMRPTFKELYEEFK

Kinase AqueK342.AA ALK 306-402 44 3e-34 115.64 In-house 179-273 (273) Show / Hide
Range on Protein: 306-402
Range on HMM: 179-273/273
Sequence Identity: 44% (43 aa)

LPIKWMALESIHDGVFSEKSDVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESVNL
.|.|||  |   ||.|  |.||||.||||||.||||  ||||       |..  |||. ||.|    | .| .|  ||      || |  ..|.   
MPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCP--QPVYRIMTQCWQHQPEDRPKFVTILEHIQY

Kinase AqueK342.AA RTKB 305-400 42 3.7e-34 112.56 In-house 170-264 (264) Show / Hide
Range on Protein: 305-400
Range on HMM: 170-264/264
Sequence Identity: 42% (41 aa)

KLPIKWMALESIHDGVFSEKS-DVWSYGVLCWEVFSLGKTPYPGLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVESV
.||||||| ||. .  .. || ||||.|| .||.|||| |||. .    . ..|  | ||  |.    .|.....|  || .  ..|| |.|||.. 
RLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPR--QMPQAADHIMQMCWQMEAQHRPDFDELVDAF

Kinase AqueK342.AA HMTK 304-399 38 5.5e-33 112.41 In-house 192-291 (291) Show / Hide
Range on Protein: 304-399
Range on HMM: 192-291/291
Sequence Identity: 38% (38 aa)

VKLPIKWMALESIH--DGVFSEKSDVWSYGVLCWEVFSLGKTPYP--GLDPSGLVELLDNGGRLQPPQNGASSQEIYALMVSCWHESSSNRPLFSELVES
||||||||| |     ...||||||||..||..||... | .||.  ..        .  |.||  |. .. . ....|| .|||   ..|| |..|  .
VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM





TyrKc AqueK342.AA TyrKc 183-400 21 3e-14 7.72 SMART 13-280 (280) Show / Hide
Range on Protein: 183-400
Range on HMM: 13-280/280
Sequence Identity: 21% (63 aa)

GRVEICITYMWGTVCD------------------DLWTNV--NAEVVCTQLGYPTT--------GAVYRHMAYFGEGRGTIYLDDVKCNGSESSLLSCSH
|.|  .. .      .                   . ...  . . .   .|. |.        . ..  | |   |    || . . .           
GEVYKGTWK-----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-----------

LSSDDHSVDCYHHEDVGVICNDI---------------D-------VSCNETVC------STKLDNA-VW----REMSDSG--PVK--LPIKWMALESIH
            ..|   .| .|               |       |. | ||       | ....   .       . ..    |  |||.|||.|.| 
----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

DGVFSEKSDVWSYGVLCWEVFSLGKTPYPG-----LDPSGLVELLDNGGRLQPPQNGA------SSQEIYALMVSCWHESSSNRPLFSELVESV
.|.|..||||||.||..||.|..|..||||     .... ..|....|.|. .|.|.        ..|.| .| .||||  ..|| |||..|  
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK342.AA Pkinase 322-400 13 9.4e-08 28.5 Pfam 190-293 (293) Show / Hide
Range on Protein: 322-400
Range on HMM: 190-293/293
Sequence Identity: 13% (14 aa)

SEKSDVWSYGVLCWEVFSLGKTPYPGL----DPSGLVELLDNGGRLQPPQNGASS---------------------QEIYALMVSCWHESSSNRPLFSEL
. |.|.||.|....|... |..|.||     .     ..... .. ... .   .                     .|   .. .|..   . || . ..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

VES--V
...  .
LQHPWF