Gene AqueK344 (A.queenslandica)

AqueK344

Species: A.queenslandica
Alias: AqueK344
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK344.AA Protein None 541 None Fasta, JSON
AqueK344.kin_dom Protein Kinase Domain None 97 None Fasta, JSON

Protein domain

Protein domains of AqueK344.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK344.AA SR 5-107 30 2.9e-31 111.12 SMART 1-118 (118) Show / Hide 
Range on Protein: 5-107
Range on HMM: 1-118/118
Sequence Identity: 30% (36 aa)

LRLVNGNRTNIGRLEICIDN----EWGTVCDDGWTHTNVEVVCRQLGYSTIGAQYFS----EKYYDTGNTSIFLNDFVCLGSEDNILQCNHSTIGSSHN-
.|||.||. . ||.|. ...    .|||||||.|. .. .|||||||...  . . .      ..  |.. | . .. | |.|... .| |...|.. | 
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CSR------SNGVSVQCF
||       .. ..| | 
CSHNHHRNRQEDAGVVCS
SRCR AqueK344.AA SRCR 8-107 35 2.3e-28 97.12 Pfam 1-112 (112) Show / Hide 
Range on Protein: 8-107
Range on HMM: 1-112/112
Sequence Identity: 35% (40 aa)

VNGNRTNIGRLEICI-DNEWGTVCDD-G-WTHTNVEVVCRQLGYSTIGAQY-FSEKY--YD--TGNTSIFLNDFVCLGSEDNILQCNHSTIGS-SHN--C
|.|.  . ||.|..  ...||||||| | |. .. .|||||||.   ..|  ... |  .    |.  | .... | |.|... ||.||  |  .||  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

SRS-NGVSVQCF
| | . ..|.| 
SHSREDAGVICS
Pkinase_Tyr AqueK344.AA Pkinase_Tyr 416-539 32 7.2e-35 118.71 Pfam 1-120 (270) Show / Hide 
Range on Protein: 416-539
Range on HMM: 1-120/270
Sequence Identity: 32% (42 aa)

ISVQETVGQGEFGIVYRGVMT-REDQMPQPVAVKTLKGFYSKSD--IDSLLDECIIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLKK
|.  .. |.|.|| ||.|...  .|.  .|||||.||  .....  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERPNLTVADTSEEDIIMNVRKQLLSICLQV
 |         |..   ..   ||..|.|.
HR---------EDKQPLTMKD-LLQMCWQI
Kinase AqueK344.AA Met 417-518 34 6.8e-26 81.63 In-house 1-105 (271) Show / Hide 
Range on Protein: 417-518
Range on HMM: 1-105/271
Sequence Identity: 34% (36 aa)

SVQETVGQGEFGIVYRGVMTREDQMPQPVAVKTLK--GFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLKKERPN
 . . .||| || ||.| .. .|.   ..|.|.|.         |   | | |.|  ||  ||| |||.|||     |... |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVAD
..| |
PCVRD
Kinase AqueK344.AA TK 416-539 15 4.6e-25 80.32 In-house 1-243 (486) Show / Hide 
Range on Protein: 416-539
Range on HMM: 1-243/486
Sequence Identity: 15% (39 aa)

ISVQETVGQGEFG---IVYRGVMTRED----------------------QMPQPVAVKTLKGFYSKSDIDSLL---------------DECIIMMS---F
| . .. |.|.||    ||.| . ...                      . ..|||||.||   . |. . ..                | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLKKERP-----------------------------NLTVADTSEEDIIMNV
.  |.. |.|||.. .           . ..|.| .|. |.    |..||.| ||                             ..  .. .... . . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

---------------RKQLLS-------------------ICLQV
                |.||.                   .|.|.
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQI
Kinase AqueK344.AA UTK 416-514 29 1.7e-20 66.82 In-house 1-108 (296) Show / Hide 
Range on Protein: 416-514
Range on HMM: 1-108/296
Sequence Identity: 29% (33 aa)

ISVQETVGQGEFGIVYRGVMTRED-QMPQ-PVAVKTLKGFYSKSD----ID---SLLDECI---IMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGS
.   .. |||.||.|...  |... .|..  ||||...   ...|     .    .. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGD

LLSYLKKERPNL
|.||| . ||..
LRSYLRRHRPTP
Kinase AqueK344.AA TK-Unique 416-539 24 1.6e-19 64.09 In-house 1-140 (294) Show / Hide 
Range on Protein: 416-539
Range on HMM: 1-140/294
Sequence Identity: 24% (35 aa)

ISVQETVGQGEFGIVYRGVMTR---EDQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
. |....|.|.|| |.|| ...   ..  .. ||||.||   .. | . .|.|  .|.. .   |.. ..|.| . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PN--------------LTVADTSEEDIIMNVRKQLLSICLQV
|.               .. |. ... |.   |.|.... |.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISP--KDLYHFAWQI
Kinase AqueK344.AA TKL 422-539 19 3.6e-19 65.67 In-house 1-141 (364) Show / Hide 
Range on Protein: 422-539
Range on HMM: 1-141/364
Sequence Identity: 19% (31 aa)

VGQGEFGIVYRGVMTRED-----QMPQPVAVKTLKG----FYSKSDID---------------------SLLDECIIMMS-FDNLNVLPLIGVCLDLGPA
.|.| ||.||.|.   ..     .. ..||||..|     . .|.. .                       . | | ||| ..  |.....|.|.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIIMNVRKQLLSICLQV
            ..|.| ....||||.||                       |.....|..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------------WHQRCRWALDI
Kinase AqueK344.AA Axl 416-511 37 4e-18 60.6 In-house 1-102 (267) Show / Hide 
Range on Protein: 416-511
Range on HMM: 1-102/267
Sequence Identity: 37% (38 aa)

ISVQETVGQGEFGIVYRGVMTREDQMPQPVAVKTLK-GFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYLKK
. .  ..|.|||| |  | .  ||   . ||||..|    ..|.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ER
 |
SR
Kinase AqueK344.AA Eph 416-517 33 7.6e-17 52.99 In-house 1-105 (264) Show / Hide 
Range on Protein: 416-517
Range on HMM: 1-105/264
Sequence Identity: 33% (36 aa)

ISVQETVGQGEFGIVYRGVMTRE-DQMPQ---PVAVKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
| ... .| |||| |..| .     .  .   |||.||||  |. ..    | |  ||  ||  |.. | ||     |.  |.  .|  ||| |.|... 
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPV-MIVTEYMENGSLDSFLRQHD

PNLTVA
  .||.
GQFTVI
Kinase AqueK344.AA MLK 416-513 28 1.3e-16 54.23 In-house 1-107 (291) Show / Hide 
Range on Protein: 416-513
Range on HMM: 1-107/291
Sequence Identity: 28% (31 aa)

ISVQETVGQGEFGIVYRGVMTREDQMPQPVAVKTLK--GFYSKSD----IDSLLDECIIMMSFDNLN----VLPLIGVCLDLGPAPYIIMPFMSRGSLLS
| ..| .| | || |..|..  .| .   ||||  .   | .|||    .. .  || .   .. .|    . .. ||||. ..  .|.| ... ||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

YLKKERPN
.|. .|..
VLHGARSK
Kinase AqueK344.AA ALK 416-513 34 5.2e-16 51.75 In-house 1-99 (273) Show / Hide 
Range on Protein: 416-513
Range on HMM: 1-99/273
Sequence Identity: 34% (34 aa)

ISVQETVGQGEFGIVYRGVMTR--EDQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPN
|      |.| || || |  .    |  | .||.|||.   |. |    . |  ||  |.  ||  .||.|..  |  .|.  .|. | ..|.|.  ||.
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH
Kinase AqueK344.AA Fer 416-510 32 3.5e-15 48.26 In-house 1-103 (283) Show / Hide 
Range on Protein: 416-510
Range on HMM: 1-103/283
Sequence Identity: 32% (34 aa)

ISVQETVGQGEFGIVYRG--VMTR-----EDQMPQPVAVKTLKGFYSKSD-IDSLLDECIIMMS-FDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSY
.  ..  | | ||.||.|  ....      .. . .|.||..|.  .. . |  .. |  ||.. .|  ||  ..||| |  |  .|.| |.. |||.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPI-MIVMEFCNGGSLDSY

LKKE
|||.
LKKN
Kinase AqueK344.AA Pkinase 416-512 23 1.1e-08 31.77 Pfam 1-102 (293) Show / Hide 
Range on Protein: 416-512
Range on HMM: 1-102/293
Sequence Identity: 23% (25 aa)

ISVQETVGQGEFGIVYRGVMTREDQMPQPVAVKTLKGFYSKSDID--SLL-DECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLK
. . ...|.| || ||...   . .    ||||..|    ||. |   ..  |. || ...  |.. |.... | .. .|..|...  |    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

--KERP
  ....
TWRHGC
Kinase AqueK344.AA TyrKc 416-539 13 1.4e-07 -100.21 SMART 1-280 (280) Show / Hide 
Range on Protein: 416-539
Range on HMM: 1-280/280
Sequence Identity: 13% (38 aa)

ISVQETVGQGEFGIVYRGVMTREDQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYL
|.  .. | |.||.||.|...      ..||||.||       .  ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERPNLTVAD--------------------------------TSEE-----------------------DIIM-----NVR------------------
.| ||.|...|                                ...                        | ..     . .                  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

-----------------------------------------------KQLLS---------------------------------ICLQV
                                               .|  .                                 |. . 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK344.AA S_TKc 416-540 12 0.000499 -117.84 SMART 1-220 (231) Show / Hide 
Range on Protein: 416-540
Range on HMM: 1-220/231
Sequence Identity: 12% (29 aa)

ISVQETVGQGEFGIVYRGVMTREDQMPQPVAVKTLKGFYSKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSR--GSLLSYLKKERPN
  . ...|.| || ||... ..     . ||.| .|        .... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

----------------------------------------------------------------------LTVADT-----------------------S
                                                                      |   ..                        
GLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFPQ

EEDIIMNVR----KQLLSICLQV-----------Q
.. .. ...    |.... |||.           |
MQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ