Gene AqueK345 (A.queenslandica)
AqueK345
Species: A.queenslandica
Alias: AqueK345
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK345.AA | Protein | None | 112 | None | Fasta, JSON |
| AqueK345.kin_dom | Protein Kinase Domain | None | 99 | None | Fasta, JSON |
Protein domains of AqueK345.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Pkinase_Tyr | AqueK345.AA | Pkinase_Tyr | 1-112 | 48 | 3.3e-53 | 180.84 | Pfam | 124-235 (270) | Show / Hide |
Range on Protein: 1-112 Range on HMM: 124-235/270 Sequence Identity: 48% (55 aa) MNYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEEIYTKNYFNQFKESKSVKLPVKWMALESLHYGTFSEKSDVWSYGVLCWEVFSAGKIP-YPGMDP |.||. ...|| ||||||||...|.|.|..||||. || . | .. ... |||.||||.|...|| |..||||||.|||.||.|. |..| ||||.. MEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY--YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSN IGLVELL-DSGQRL ..|.. ..|.|. EEVYEYIYEDGYRM |
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| Kinase | AqueK345.AA | TK | 1-112 | 31 | 1.1e-46 | 154.11 | In-house | 247-423 (486) | Show / Hide |
Range on Protein: 1-112 Range on HMM: 247-423/486 Sequence Identity: 31% (56 aa) MNYLALQ------KFIHCDLAARNCLIADNGV-----------IKVADFG--------LSEEIYT-KNYFNQFKESKSV--------------------K | ||. . .|.| ||||||||...|.| .|.|||| |. .|| ..| . ..... | MEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGK LPVKWMALESLH---------YGTFSEKSDVWSYGVLCWEVFSAGKIPYPGMDPI----------GLVELLDSGQRL ||..||| |.| ||.|..||||||.|||.||.|. |. ||.|. . ..|.| .|.|| LPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRL |
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| Kinase | AqueK345.AA | Met | 1-112 | 43 | 1.1e-45 | 147.53 | In-house | 117-241 (271) | Show / Hide |
Range on Protein: 1-112 Range on HMM: 117-241/271 Sequence Identity: 43% (54 aa) MNYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEEI-YTKNYFNQFKESKSVKLPVKWMALESLH---------YGTFSEKSDVWSYGVLCWEVFSAG |.|.| |||.| |||.|||.. ..|||||||. . | | | | . .|||||||.|.| | |. |||||| ||. || . | MMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRG KIPYPGMDP-IGLVELLDSG--QRL ||| .|. . . | | || APPYPHVDNWFDITHWLHQGETRRL |
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| Kinase | AqueK345.AA | UTK | 1-97 | 39 | 2.2e-44 | 149.77 | In-house | 131-244 (296) | Show / Hide |
Range on Protein: 1-97 Range on HMM: 131-244/296 Sequence Identity: 39% (45 aa) MNYLALQKFIHCDLAARNCLIADNG-------VIKVADFG---LSEEIYT------KNYFNQFKESKSVKLPVKWMALESLHYG-TFSEKSDVWSYGVLC |.||. ..|.|.||||||||..... |.|.|||| .| ...| . . .. . ..|..||| |.| .. .|..||||||.||.| MQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVC WEVFSAGKIPYPGM ||... |. ||||| WEIWTWGRLPYPGM |
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| Kinase | AqueK345.AA | TK-Unique | 1-112 | 40 | 1.8e-42 | 144.27 | In-house | 144-258 (294) | Show / Hide |
Range on Protein: 1-112 Range on HMM: 144-258/294 Sequence Identity: 40% (48 aa) MNYLAL--QKFIHCDLAARNCLIADNGVIKVADFGLSEEIYTKNYFNQFKES-KSVKLPVKWMALESLH--YGTF-SEKSDVWSYGVLCWEVFSAGKIPY |.||| .|..| ||.|||.|.....|.|..|||.....|| .. . .. ..|..|||.||| .|.. ..||||||.||| ||.|. |. || MEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT---NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPY PGMDPIGLVELLDSGQRL |||.. ..|.. | |. PGMPWKDIMECIRDGYRM |
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| Kinase | AqueK345.AA | HMTK | 1-96 | 45 | 7.7e-42 | 143.71 | In-house | 141-239 (291) | Show / Hide |
Range on Protein: 1-96 Range on HMM: 141-239/291 Sequence Identity: 45% (46 aa) MNYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEEIY-TKNYFNQFKESKSVKLPVKWMALESLH--YGTFSEKSDVWSYGVLCWEVFSAGKIPYP-- | |.| | ..| ||||||||...| ..|.|||||. . ..|. . | . ||||.|||| | . ...||||||||..||..||... | ||. MAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHM--VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQ G . Q |
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| Kinase | AqueK345.AA | Src | 1-112 | 41 | 2.3e-39 | 131.34 | In-house | 110-219 (255) | Show / Hide |
Range on Protein: 1-112 Range on HMM: 110-219/255 Sequence Identity: 41% (47 aa) MNYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEEIYTKNYFNQFKESKSVKLPVKWMALESLHYGTFSEKSDVWSYGVLCWEVFSAGKIPYPGMDPI |.|| ...|| |||||| |. .| | ||||||| . .. . .. |.|.||.| | ..||.|. ||||||.|.| .|... |..|||||. MAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKED-DDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNH GLVELLDSGQRL .. .. | |. EVLQQVERGYRM |
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| Kinase | AqueK345.AA | Musk | 1-97 | 47 | 4.8e-39 | 126.51 | In-house | 139-232 (282) | Show / Hide |
Range on Protein: 1-97 Range on HMM: 139-232/282 Sequence Identity: 47% (46 aa) MNYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEEIYTKNYFNQFKESKSVKLPVKWMALESLHYGTFSEKSDVWSYGVLCWEVFSAGKIPYPGM | || .|.| ||| ||||| .. ..|.|||||| .|| ..| .| . |. ||..||. | |. ||||.|||. ||.|| . || || MAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDY---YKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYALQPYYGM |
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| Kinase | AqueK345.AA | Src-Unclassified | 1-112 | 44 | 2.3e-38 | 129.11 | In-house | 132-246 (284) | Show / Hide |
Range on Protein: 1-112 Range on HMM: 132-246/284 Sequence Identity: 44% (53 aa) MNYLALQKFIHCDLAARNCLIADNG-----VIKVADFGLS--EEIYTKNYFNQFKESKSVKLPVKWMALESLHYGTFSEKSDVWSYGVLCWEVFSAGKIP |.|| | .| |||||| || .| | ||.|||| . || . ..|.|||| | ||.|| ||||||||.| ||.. |..| MMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMR----TGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQTP YPGMDPIGLVELLDSGQRL ||||. . .| . .| |. YPGMHNREVLEHVERGYRM |
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| Kinase | AqueK345.AA | FGFR | 1-112 | 44 | 1.7e-37 | 125.34 | In-house | 149-258 (293) | Show / Hide |
Range on Protein: 1-112 Range on HMM: 149-258/293 Sequence Identity: 44% (50 aa) MNYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEEIYTKNYFNQFKESKSVKLPVKWMALESLHYGTFSEKSDVWSYGVLCWEVFSAGKIPYPGMD-P |.||| .| || |||||| |. |. |.|..||||. | | .. ||.||||.|.| . .||||||||| ||.. | |||. MEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDY---YRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSV IGLVELLDSGQRL | ..| .|.|. EELYKYLKEGHRM |
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| Kinase | AqueK345.AA | VEGFR | 1-99 | 47 | 1.3e-36 | 128.01 | In-house | 186-283 (332) | Show / Hide |
Range on Protein: 1-99 Range on HMM: 186-283/332 Sequence Identity: 47% (48 aa) MNYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEE-IYTK-NYFNQFKESKS-VKLPVKWMALESLHYGTFSEKSDVWSYGVLCWEVFSAGKIPYPGM | .|| .| || |||||| |.. | |.| ||||. ||. .| . . . .|| ||||.||. .. .||||||||. ||.|| |. |||| MEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDY----VRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGV DP .. QI |
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| Kinase | AqueK345.AA | TyrKc | 1-112 | 19 | 3.9e-11 | -42.56 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1-112
Range on HMM: 1-280/280
Sequence Identity: 19% (54 aa)
M---------------------------------------------------------------------------------------------------
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK
-------------NYLALQKFIHCDLAARNCLIADNGVIKVADFGLSEEIYTK-------NYFNQFKESKSVK--LPVKWMALESLHYGTFSEKSDVWSY
.||. ...|| ||||||||...|...|..||||| .|| . | . ||.|. | ||..|||.|.. ||.|..||||||.
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRK-KEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF
GVLCWEVFSAGKIPYPG-----MDPIGLVELLDSG-------------------------------------------QRL
||..||.|. |. |||| |... ..|....| ...
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
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| Kinase | AqueK345.AA | Pkinase | 7-96 | 31 | 1.8e-08 | 31.01 | Pfam | 127-214 (293) | Show / Hide |
Range on Protein: 7-96 Range on HMM: 127-214/293 Sequence Identity: 31% (30 aa) QKFIHCDLAARNCLIADNGVI----KVADFGLSEEIYTKNYFNQFKESKSVKLPVKWMALESLH-YGTFSEKSDVWSYGVLCWEVFSAGKIPYPG ...||.|| |.|| .||.| |..||||.. .. | |. ... .|| | . . . |.|.||.|....|... |. |.|| MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPG |
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