Gene AqueK359 (A.queenslandica)

AqueK359

Species: A.queenslandica
Alias: AqueK359
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK359.AA Protein None 750 None Fasta, JSON
AqueK359.kin_dom Protein Kinase Domain None 188 None Fasta, JSON

Protein domain

Protein domains of AqueK359.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CCP AqueK359.AA CCP 11-70 21 4.8e-08 33.96 SMART 1-79 (79) Show / Hide 
Range on Protein: 11-70
Range on HMM: 1-79/79
Sequence Identity: 21% (18 aa)

CELMV---DSNEGLSVSYS-----SNRSTKPYNSIAMYSCNKDGYSLVG-----------DAVRICLSSGNWSQSP----PYC
|       |   |  ....     ..  | .|.. . ||||.  |.|.|            ... |...  || .|    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPG-YTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK359.AA Sushi 24-70 20 4e-06 24.63 Pfam 15-65 (65) Show / Hide 
Range on Protein: 24-70
Range on HMM: 15-65/65
Sequence Identity: 20% (11 aa)

SYSSNR-----STKPYNSIAMYSCNKDGYSLVGD--AVRICLSSGNWSQSPPY-C
......     .  ...| . |.| ..|| ..|.  ....|  .| |....|  |
VIHTTKWRCYRN-YQFGSKVYYEC-DPGYQMMGQGSNTITC--NGQWTPPFPTPC
CCP AqueK359.AA CCP 75-132 25 3.4e-13 51.08 SMART 1-79 (79) Show / Hide 
Range on Protein: 75-132
Range on HMM: 1-79/79
Sequence Identity: 25% (21 aa)

CSELM---VESNEGLSVSYSS------NTKPYNSIATYSCEDGYSLVG-----------NAVRTCLSSGNWSGNP----PYC
|. .    .  |  ...| |.      .| .|.. .||||..||.|.|           ....||...  ||. |    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK359.AA Sushi 75-132 21 5.2e-09 34.85 Pfam 1-65 (65) Show / Hide 
Range on Protein: 75-132
Range on HMM: 1-65/65
Sequence Identity: 21% (15 aa)

CS----ELMVESNEGLSVSYSS-----NTKPYNSIATYSCEDGYSLVGN--AVRTCLSSGNWSGNPPY-C
|.    ..    . |.....       |  ...| ..|.|..|| ..|.  ...||  .| |.. .|  |
CPFDPPDP-N-IPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
CCP AqueK359.AA CCP 137-194 26 1.2e-13 52.53 SMART 1-79 (79) Show / Hide 
Range on Protein: 137-194
Range on HMM: 1-79/79
Sequence Identity: 26% (22 aa)

CSELM---VDSNEGLSVSYSS------NTKPYNSTATYSCEDGYSLVG-----------DAIRTCLSSGNWSGNP----PYC
|. .    .  |  ...| |.      .| .|..|.||||..||.|.|            ...||...  ||. |    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi AqueK359.AA Sushi 137-194 21 1.6e-09 36.66 Pfam 1-65 (65) Show / Hide 
Range on Protein: 137-194
Range on HMM: 1-65/65
Sequence Identity: 21% (15 aa)

CS----ELMVDSNEGLSVSYSS-----NTKPYNSTATYSCEDGYSLVGD--AIRTCLSSGNWSGNPPY-C
|.    ..    . |.....       |  ...|...|.|..|| ..|.  ...||  .| |.. .|  |
CPFDPPDP-N-IPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
Kinase AqueK359.AA Pkinase_Tyr 345-553 39 5.4e-82 278.31 Pfam 40-240 (270) Show / Hide 
Range on Protein: 345-553
Range on HMM: 40-240/270
Sequence Identity: 39% (85 aa)

YSKSD--IDSLLDECIIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIIQNVRKQLLSICLQVGNGMCYLAS
.....  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.||.| |         |..   ..   ||..|.|. .|| ||.|
AMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR---------EDKQPLTMKD-LLQMCWQIAKGMEYLES

QKFIHRDLAARNCMIDDDGIIKVSDFGLSEDIYSQNYF-RQLEGDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVP-YPGLDPMG
...||||||||||........|..||||. |||.  |  |. .|       ||| ||||.|.|..| |..||||||.|||.||.|..|. | |||...  
KNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG------KLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEE

IVELL-NTGGRLHTPNN
..|..   |.|.  | |
VYEYIYEDGYRMPCPEN
Kinase AqueK359.AA TK 354-561 21 5.6e-71 236.96 In-house 86-462 (486) Show / Hide 
Range on Protein: 354-561
Range on HMM: 86-462/486
Sequence Identity: 21% (83 aa)

LDECIIMMSFD-----NLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLKKERP-----------------------------N
| |. .|. ..       |.. |.|||.. .           . ..|.| .|. |.    |..||.| ||                             .
LEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDIT

LTVADTSEEDIIQNV---------------RKQLLS-------------------ICLQVGNGMCYLASQ------KFIHRDLAARNCMIDDDGI-----
.  .. .... ...                 |.||.                   .|.|. .|| ||.|.      .|.|||||||||.......     
Y-SHESNSPC-PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHF

------IKVSDFG--------LSEDIYS-QNYFRQLEGDNNS-----------------SPVKLPLKWMALESIHDGL---------FSEKSDVWSYGVL
      .|..|||        |. |||| ..| |. ... .                  |  |||..||| |.. |.          |..||||||.|||
DGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVL

CWEVFSLGRVPYPG-LDP---------MGIVELLNTGGR------------LHTPNNEACS--------------KEIF
.||.|..|..||.| ..            ..|.| .|||            .  |  . |.              .|..
MWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYY
Kinase AqueK359.AA UTK 279-561 25 4e-67 228.68 In-house 1-272 (296) Show / Hide 
Range on Protein: 279-561
Range on HMM: 1-272/296
Sequence Identity: 25% (80 aa)

LKILETVGRGEFGIVYRGLI-SVKNDIPQ-AVAAKTLRXXXXXXXXXXXXXXXXXXXXXXXXXXXRSFYSKSDID---SLLDECI---IMMSFD-NLNVL
...... |.|.||.|...    ...  .. .|| |...                           ..  .  . .    .. |.    .|. |.   |||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---------------------------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVL

PLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIIQNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNCMIDDDG-------IIKV
 |.|||.. .| ..|.. .|..|.|.||| . ||..      ... ... . |.|. .... .|| ||.|..|.||||||||| .....       ..|.
RLVGVCTQEEP-WMIVTEYMENGDLRSYLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKI

SDFG---LSEDIY---------SQNYFRQLEGDNNSSPVKLPLKWMALESIHDG-LFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLH
.|||   .| ...         ...|...      ..  ..|..||| |.. ..  |..||||||.||.|||... ||.||||.  | ... .  |||..
ADFGRGGMSRRVNTFHFSNRYWESYYYMA------QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYR

TPNNEACSKEIF
 | ...|. ...
MPCPWDCPHPVY
Kinase AqueK359.AA Met 354-551 39 1.6e-65 213.72 In-house 49-244 (271) Show / Hide 
Range on Protein: 354-551
Range on HMM: 49-244/271
Sequence Identity: 39% (84 aa)

LDECIIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIIQNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNC
| | |.|  ||  ||| |||.|||     |... |.|  | |... . .  |..|             ..|.. |.||  || |.|||||.|||||.|||
LREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNNPCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNC

MIDDDGIIKVSDFGLSEDI-YSQNYFRQLEGDNNSSPVKLPLKWMALESIH--------DGL-FSEKSDVWSYGVLCWEVFSLGRVPYPGLDP-MGIVEL
|.| . ..|| ||||. |. |   |  |    .   | .||.||||.|.          .   |. |||||| ||. || .  | .|||  |.   |   
MLDEHFTVKVADFGLCRDMDYDKEYYSQ---MHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHW

LNTG--GRLHTP
| .|   ||  |
LHQGETRRLPQP
Kinase AqueK359.AA TyrKc 342-587 30 2e-59 204.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 342-587
Range on HMM: 1-280/280
Sequence Identity: 30% (91 aa)

RSFYSK--------------------------SDIDSLLDECIIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYLKKERPNLTV
 ..  |                          . .  ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..||.| ||.   
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK---

ADTSEEDIIQNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNCMIDDDGIIKVSDFGLSEDIYSQ-------NYFRQLEGDNNSSPVK--LPLKWMAL
        ...  |.|||.|.|. .|| ||.|...||||||||||........|.|||||| |||.         | |. |.    .  |  ||..|||.
--------LCM--KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH----KGGKTMLPIRWMAP

ESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPG-----LDPMGIVELLNTGGRLHTPNNEA------CSKEIFAGRGFSGDHIIEADDASTFINLSSCI
|.| .| |..||||||.||..||.|..|  ||||     ...  ..|.. .|.|.  | |        |..|..     .     ...|  || .. .|.
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK359.AA TK-Unique 346-561 32 1e-58 201.03 In-house 43-270 (294) Show / Hide 
Range on Protein: 346-561
Range on HMM: 43-270/294
Sequence Identity: 32% (76 aa)

SKSDIDSLLDECIIMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPN--------------LTVADTSEEDIIQNVRKQLLSICLQV
.. | . .|.|  .|.. .   |.. ..|.| . .  ..|||.....|.|..||.. ||.               .. |. ... |.   |.|.... |.
TDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISP--KDLYHFAWQI

GNGMCYLAS--QKFIHRDLAARNCMIDDDGIIKVSDFGLSEDIYSQNYFRQLEGDNNSSPVKLPLKWMALESIH--DGLF-SEKSDVWSYGVLCWEVFSL
 .|| ||||  .|..||||.|||... .|...|..|||...|.|        . ... |  ..|..|||.||.   .| . ..||||||.||| ||.|.|
ACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-----NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTL

GRVPYPGLDPMGIVELLNTGGRLHTPNNEAC-SKEIF
|  ||||...  |.|..  | |.  |..  | |.|..
GACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMY
Kinase AqueK359.AA Csk 350-531 41 4.8e-51 172.43 In-house 38-199 (251) Show / Hide 
Range on Protein: 350-531
Range on HMM: 38-199/251
Sequence Identity: 41% (76 aa)

IDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIIQNVRKQLLSICLQVGNGMCYLASQKFIHRDLAA
....|.|  .|      |   |||| |. .   ||.| .||.|.|. ||           . .. .|.  |.|||   . |..||||| . ||.||||||
AQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLR----------SRGRHVIT--RRQLLKFAMDVCEGMCYLEQKKFVHRDLAA

RNCMIDDDGIIKVSDFGLSEDIYSQNYFRQLEGDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYP
||  ...| . |||||||. .  ||       .|  |.  |.| || | |    . || ||||||.|.| ||..| ||||||
RNILVSEDCVAKVSDFGLAKEECSQ------QDDSTSG--KFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRVPYP
Kinase AqueK359.AA VEGFR 421-535 47 1.8e-50 174.01 In-house 173-283 (332) Show / Hide 
Range on Protein: 421-535
Range on HMM: 173-283/332
Sequence Identity: 47% (56 aa)

KQLLSICLQVGNGMCYLASQKFIHRDLAARNCMIDDDGIIKVSDFGLSED-IYSQ-NYFRQLE-GDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGV
. |..  .|| .|| .|||.| |||||||||  .. . ..| .||||. . ||.  .| |. . |       .||.||||.||| |  .. .||||||||
EDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQG-------RLPIKWMAPESIFDKVYTTYSDVWSYGV

LCWEVFSLGRVPYPGLDP
. ||.|||| .|||| ..
FLWEIFSLGGSPYPGVQI
Kinase AqueK359.AA InsR 354-533 39 2.9e-50 166.96 In-house 52-225 (278) Show / Hide 
Range on Protein: 354-533
Range on HMM: 52-225/278
Sequence Identity: 39% (72 aa)

LDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDII----QNVRKQLLSICLQVGNGMCYLASQKFIHRDLAA
| |  .|  |.  .|  | |||    |. |..| .| .| | |||   ||        . ...    .  . |...   ..  || |||. ||.|||||.
LNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRRPEEEF---NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLAC

RNCMIDDDGIIKVSDFGLSEDIYSQNYFRQLEGDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGL
||||...|. .|. |||.  |||   | |   .       .||  ||| ||. || |. .|||||.||. ||. .||  || ||
RNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGK------GMLPVRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGL
Kinase AqueK359.AA Axl 346-562 37 5.7e-50 172.32 In-house 41-246 (267) Show / Hide 
Range on Protein: 346-562
Range on HMM: 41-246/267
Sequence Identity: 37% (84 aa)

SKSDIDSLLDECIIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIIQNVRKQLLSICLQVGNGMCYLASQ
..|.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|   |         ... .    . |.   . .  || ||...
TQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLYSR--------LGDQPFYLPLQMLVKFMVDIACGMEYLSNR

KFIHRDLAARNCMIDDDGIIKVSDFGLSEDIYSQNYFRQLEGDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVE
.||||||||||||. .|  . | |||||  |||  |.||          |.| ||.|.||. | ..  |||||..||  ||.   |. ||||..   . .
NFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQ------GCIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYD

LLNTGGRLHTPNNEACSKEIFA
 |  | ||  |  | |  |...
YLIHGHRLKQP--EDCMDELYD
Kinase AqueK359.AA ALK 354-553 39 8.5e-48 163.07 In-house 50-241 (273) Show / Hide 
Range on Protein: 354-553
Range on HMM: 50-241/273
Sequence Identity: 39% (81 aa)

LDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLTVADTSEE--DIIQNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARN
. |  ||  |.  ||  .||.|..  |  .|.  .|. | ..|.|.  ||.       .|     | . | || .|. |  |  || ...||||| ||||
CMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARN

CMIDDDG---IIKVSDFGLSEDI-YSQNYFRQLEGDNNSSPVKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGR
|     |   . |. ||| . || |   |.|   |.       .| |||  |   ||.|  |.||||.||||||.||||..||||     . |.. .|||
CLLTCKGPGRVAKIADFGMARDITYRADYYRK--GGR----AMMPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGR

LHTPNN
.  | |
MDPPRN
Kinase AqueK359.AA Tec 373-561 38 4.9e-47 162.38 In-house 61-228 (254) Show / Hide 
Range on Protein: 373-561
Range on HMM: 61-228/254
Sequence Identity: 38% (73 aa)

GVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLTVADTSEEDIIQNVRKQ--LLSICLQVGNGMCYLASQKFIHRDLAARNCMIDDDGIIKVSDFGLSED
|||.   |  ||.  .|..|.||.||....  .              ...  ||..|..|  || || ...||||||||||| ..|....||||||..  
GVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHFQ-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRY

IYSQNYFRQLEGDNNSSP-VKLPLKWMALESIHDGLFSEKSDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSKEIF
.    |         ||   | | || . |  |   .| |||||..||| |||||.|..||. .. . .||   .| ||. |  . ||..|.
VLDDQYT--------SSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP--HLCSMHIY
Kinase AqueK359.AA Pkinase 367-541 22 2.4e-17 62.4 Pfam 61-229 (293) Show / Hide 
Range on Protein: 367-541
Range on HMM: 61-229/293
Sequence Identity: 22% (44 aa)

NVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLKKERPNLTVADTSEEDIIQN--VRKQLLSICLQVGNGMCYLASQKFIHRDLAARNCMIDDDGII
|.. |.... | .. .|..|...  |    .| .|..             ..        ... ....|.  |. |. |...|||||   |..||..| |
NIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHI

----KVSDFGLSEDIYSQNYFRQLEGDNNSSPVKLPLKWMALESIH-DGLFSEKSDVWSYGVLCWEVFSLGRVPYPGL------DPMGIVEL
    |..||||.. ..       .  .   . .   . .|| | |  .   . |.|.||.|....|... || |.||       |.| ....
DACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICR
Kinase AqueK359.AA S_TKc 345-581 16 1.5e-12 7.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 345-581
Range on HMM: 1-231/231
Sequence Identity: 16% (47 aa)

YSKSDI---------------------------DSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSR--GSLLSYLKKERPN-----LTVADT
| . ..                           .... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| ...     ..  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

SEEDIIQNVRKQLLSICLQVGNGMCYLASQKFIHRDLAARNCMIDDDGIIKVSDFGLSEDIYSQNYFRQLEGDNNSSPVKLPLKWMALESIHDGLFSE-K
              ... |. ... |. |...|||||   | ..|.   ||..||||.  .               . .   . .|| | .    ..  |
R-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---GYGKCK

SDVWSYGVLCWEVFSLGRVPYPGLDPMGIVELLNTGGRLHTPNNEACSKEIFAGRGFSGDHI--IEADDAST---------FI
.|.|| |.. .| .. |. |.|  ... . ...               |. |  . .  |    . | .| .         ..
CDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK359.AA TK 279-314 19 3.7e-07 19.24 In-house 1-61 (486) Show / Hide 
Range on Protein: 279-314
Range on HMM: 1-61/486
Sequence Identity: 19% (12 aa)

LKILETVGRGEFG---IVYRGLISV----------------------KNDIPQAVAAKTLR
...... |.|.||    ||.|.                         |.. .. || |.|.
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLK
Kinase AqueK359.AA TK-Unique 279-314 33 5.6e-07 20.22 In-house 1-39 (294) Show / Hide 
Range on Protein: 279-314
Range on HMM: 1-39/294
Sequence Identity: 33% (13 aa)

LKILETVGRGEFGIVYRGLISVKN---DIPQAVAAKTLR
|......|.|.|| |.|| .. ..   | .. || |.|.
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK
Kinase AqueK359.AA Pkinase_Tyr 279-314 29 4e-06 21.45 Pfam 1-37 (270) Show / Hide 
Range on Protein: 279-314
Range on HMM: 1-37/270
Sequence Identity: 29% (11 aa)

LKILETVGRGEFGIVYRGLIS-VKNDIPQAVAAKTLR
...... |.|.|| ||.|     . .  . || |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Kinase AqueK359.AA ALK 279-314 39 0.000215 11.09 In-house 1-38 (273) Show / Hide 
Range on Protein: 279-314
Range on HMM: 1-38/273
Sequence Identity: 39% (15 aa)

LKILETVGRGEFGIVYRGLISV-KND-IPQAVAAKTLR
.. .   |.| || || |. |   .|  | .|| |||.
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLP
Kinase AqueK359.AA Met 280-313 29 0.000372 9.2 In-house 1-34 (271) Show / Hide 
Range on Protein: 280-313
Range on HMM: 1-34/271
Sequence Identity: 29% (10 aa)

KILETVGRGEFGIVYRGLISVKNDIPQAVAAKTL
  .. .|.| || ||.|  . .      .| |.|
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSL
Kinase AqueK359.AA Csk 279-296 50 0.001461 8.07 In-house 1-18 (251) Show / Hide 
Range on Protein: 279-296
Range on HMM: 1-18/251
Sequence Identity: 50% (9 aa)

LKILETVGRGEFGIVYRG
|...|..| |||| |  |
LHLGECIGHGEFGDVMQG
Kinase AqueK359.AA InsR 279-313 25 0.001891 7.34 In-house 1-39 (278) Show / Hide 
Range on Protein: 279-313
Range on HMM: 1-39/278
Sequence Identity: 25% (10 aa)

LKILETVGRGEFGIVYRG----LISVKNDIPQAVAAKTL
. ..   | | || || |    ...   ..  ..| ||.
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTV
Kinase AqueK359.AA Tec 279-296 38 0.002649 7.49 In-house 1-18 (254) Show / Hide 
Range on Protein: 279-296
Range on HMM: 1-18/254
Sequence Identity: 38% (7 aa)

LKILETVGRGEFGIVYRG
|.... .|.| ||.| .|
LTFMKELGSGQFGVVHLG
Kinase AqueK359.AA Pkinase 279-296 38 0.012332 10.4 Pfam 1-18 (293) Show / Hide 
Range on Protein: 279-296
Range on HMM: 1-18/293
Sequence Identity: 38% (7 aa)

LKILETVGRGEFGIVYRG
..|....|.| || ||..
YHIGRKIGSGSFGCVYKC
Kinase AqueK359.AA Axl 279-314 27 0.064775 2.3 In-house 1-36 (267) Show / Hide 
Range on Protein: 279-314
Range on HMM: 1-36/267
Sequence Identity: 27% (10 aa)

LKILETVGRGEFGIVYRGLISVKNDIPQAVAAKTLR
. .  ..|.|||| |  | .       . || |...
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMK
SR AqueK359.AA SR 591-691 34 2.2e-37 131.46 SMART 1-118 (118) Show / Hide 
Range on Protein: 591-691
Range on HMM: 1-118/118
Sequence Identity: 34% (41 aa)

LKLVNGKT-TIGRLEICINN----EWGTVCDDGWTHTNAEVVCRQLGYSTIGAQYFN----GKYFDAENMSIFLDDVVCLGSEDNILQCNHSTIGFHN--
. ||.| .   ||.|. .|.    .|||||||.|. ..|.|||||||...  . . .    . .| . .  | .|.| | |.|... .| |...| ||  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CSH------SNDVSVQCF
|||      ..|..| | 
CSHNHHRNRQEDAGVVCS
SRCR AqueK359.AA SRCR 594-691 41 1.4e-32 111.3 Pfam 1-112 (112) Show / Hide 
Range on Protein: 594-691
Range on HMM: 1-112/112
Sequence Identity: 41% (46 aa)

VNGKT-TIGRLEICI-NNEWGTVCDD-G-WTHTNAEVVCRQLGYSTIGAQY-FNGKY--FD--AENMSIFLDDVVCLGSEDNILQCNHSTIGF--HN--C
|.|..   ||.|..  |..||||||| | |. ..|.|||||||.   ..|  ... |  |   . .  | .|.| | |.|... ||.||  |   ||  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

SHS-NDVSVQCF
||| .|..|.| 
SHSREDAGVICS