AqueK377

Species: A.queenslandica
Alias: AqueK377
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK377.AA Protein None 682 None Fasta, JSON
AqueK377.kin_dom Protein Kinase Domain None 275 None Fasta, JSON

Protein domain

Protein domains of AqueK377.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
EGF AqueK377.AA EGF 268-305 34 3.1e-05 24.62 SMART 1-32 (32) Show / Hide
Range on Protein: 268-305
Range on HMM: 1-32/32
Sequence Identity: 34% (15 aa)

ICEKDSPCMNG-----GQCIQYSPPDNYTCNCTGTGYQRVNCT
 |.   || .|     |.||       ||| | | ||.  .| 
ECA---PCHHGGCEQHGTCI------SYTC-CPGPGYTG-RCE

EGF AqueK377.AA EGF 269-302 23 8.4e-05 19.12 Pfam 1-36 (36) Show / Hide
Range on Protein: 269-302
Range on HMM: 1-36/36
Sequence Identity: 23% (9 aa)

CEKD-SPCMNGGQCIQYSPPDNYTCNCTGT---GYQRV
| .. .||...|.|..    . ||| |.     . .. 
CNPNNNPCHHHGTCVDTP--GGYTCQCPPGYLGYTGKR

Pkinase_Tyr AqueK377.AA Pkinase_Tyr 381-655 39 9.20000000001e-112 379.13 Pfam 1-270 (270) Show / Hide
Range on Protein: 381-655
Range on HMM: 1-270/270
Sequence Identity: 39% (111 aa)

IDIQETIGQGEFGIVYKATII--MDKSRQEIALKTLKGAFSKSD--VNSLLEECLLMSNF-NNPNVLSLIGVCADLGSA--PGIILPYMSRGSLLSYLQK
| . ...|.|.|| |||.|    .|. ... | |.||   ....    ....|  .|... ..||...|.||| | |    . |...||  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

EKSHLIVGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTKNYFNQFKESKSVKLPVKWMALESLYY
 .         |.   |..   ||. |.|.|.||.||.|...|||| ||||||...|.|.|..||||.  .| . |   .. ... |||.||||.|.. |
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY--YRKRGGGKLPIKWMAPECINY

GIFSEKSDVWSYGILCWEVFSAGKIP-YPGMDPTGLVELL-DGGQRLSCPHNAACSEDVYSLMQQCWRESPDDRPLFSDLVASV
|.|..||||||.|.|.||.|. |..| ||||... ..|.. . |.|. ||.|  |....|.||.|||.. |.||| ||...   
GKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

TyrKc AqueK377.AA TyrKc 381-655 36 2.2e-108 367.27 SMART 1-280 (280) Show / Hide
Range on Protein: 381-655
Range on HMM: 1-280/280
Sequence Identity: 36% (110 aa)

IDIQETIGQGEFGIVYKATIIMDKSRQEIALKTLK-GAFSKSDVNSLLEECLLMSNF--NNPNVLSLIGVCADLG------SAPGIILPYMSRGSLLSYL
|   ...| |.||.|||.| .     .. | |.|| .|     .  ...|  .|...  ..||.. |.||| . |        . |.. ||. |.|..||
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

QKEKSHLIVGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTK-------NYFNQFKESKSVK--LP
.| . .            |.. |.||| |.|.|.||.||.|...|||| ||||||...|...|..||||| ..| .        |  . ||.|. |  ||
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRK-KEHKGGKTMLP

VKWMALESLYYGIFSEKSDVWSYGILCWEVFSAGKIPYPG-----MDPTGLVELLDGGQRLSCPHNAA------CSEDVYSLMQQCWRESPDDRPLFSDL
..|||.|.. ||.|..||||||.|...||.|. |. ||||     |... ..|... | |. .|.|.       |....|..|.|||.| |.||| ||..
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

VASV
.   
HECF

Kinase AqueK377.AA TK 381-655 22 5.1e-99 332.63 In-house 1-486 (486) Show / Hide
Range on Protein: 381-655
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

IDIQETIGQGEFG---IVYKATIIM-----------------------DKSRQEIALKTLKGAFSKSDVNSLL-------------EECLLMSNFN----
| . ...|.|.||    |||.. ..                       .. ... | |.||   . |.   ..             ||.. |. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-NPNVLSLIGVCADLG-----------SAPGIILPYMSRGS----LLSYLQKEKSHLIV---------------------------------GETSEEST
  ||...|.||| . .             . |.. ||. |.    |..||.| . . .                                  .. .||..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

VLNV----------RKQLLS-------------------VCLQVANGMNYLASQ------RFIHRDFAARNCLIADNGV-----------IKVADFG---
...            |.||.                    |.|.|.|| ||.|.      .|.||| ||||||...|.|           .|.||||   
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSEEVYT-KNYFNQFKESKSV--------------------KLPVKWMALESLY---------YGIFSEKSDVWSYGILCWEVFSAG-KIPYPGM
     |. ..|  ..|  .  .....                    |||..||| |.|          ||.|..||||||.|.|.||.|. | . .|.||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DP---------TGLVELLDGGQR------------LSCPHNAACS--------------EDVYSLMQQCWRESPDDRPLFSDLVASV
.          . ..|.|  |.|            . .|  . |.              |..| ||||||.. |.||| ||.|.   
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK377.AA Met 382-649 36 2.9e-92 302.82 In-house 1-271 (271) Show / Hide
Range on Protein: 382-649
Range on HMM: 1-271/271
Sequence Identity: 36% (104 aa)

DIQETIGQGEFGIVYKATIIM-DKSRQEIALKTLK--GAFSKSDVNSLLEECLLMSNFNNPNVLSLIGVCADLGS-APGIILPYMSRGSLLSYLQKEKSH
.  . |||| || ||... .  |  .  .| |.|.   .     .   |.| ..|. |. ||||||||.| |  .  | ..||||  | |...   ..  
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LIVGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEV-YTKNYFNQFKESKSVKLPVKWMALESLY----
. |             ..|.. |.||| ||.|.|||.|.||| |.|||..    ..|||||||.  . | | |  |  .    .|||||||.|.|     
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVC

----YGI-FSEKSDVWSYGILCWEVFSAGKIPYPGMDP-TGLVELLDGG--QRLSCPHNAACSEDVY-SLMQQCWRESPDDRPLFS
      . |. |||||| |.. || .  |  ||| .|. . .   | .|   ||. |    | . .|  .|..||. .| ||| ||
LGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEY--CPDHLYTDVMLCCWHANPEDRPQFS

Kinase AqueK377.AA UTK 381-655 32 5e-89 302.07 In-house 1-296 (296) Show / Hide
Range on Protein: 381-655
Range on HMM: 1-296/296
Sequence Identity: 32% (99 aa)

IDIQETIGQGEFGIVYKATIIMDK---SRQEIALKTLK-GAFSKSDVN---SLLEECL---LMSNFN-NPNVLSLIGVCADLGSAPGIILPYMSRGSLLS
. . ...|||.||.|.||.   ..     .  |.|... .|..  .      ..||.    .|..|.  |||| |.||| . .  . |.. ||..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLQKEKSHLIVGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNG-------VIKVADFG---LSEEVYT------KNYFNQF
||.. .  .      .. . |. . |.|. ....|.||.||.|..|.||| ||||||.....       |.|.||||   .| .|.|        . . .
YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYY

KESKSVKLPVKWMALESLYYG-IFSEKSDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAACSEDVYSLMQQCWRESPDDRPLFSDLV
. .   ..|..||| |.|...  |..||||||.|..|||... |. |||||    ... .  | |.  | ...|...|| ||..||. .|..|| | |||
MAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLV

ASV
. .
QQM

Kinase AqueK377.AA TK-Unique 381-655 30 9.3e-84 284.57 In-house 1-294 (294) Show / Hide
Range on Protein: 381-655
Range on HMM: 1-294/294
Sequence Identity: 30% (92 aa)

IDIQETIGQGEFGIVYKATII---MDKSRQ-EIALKTLKGAFSKSDVNSLLEECLLMSNFN-NPNVLSLIGVCADLGSAPGIILPYMSRGSLLSYLQKEK
. ....||.|.|| |.....    .. ..|  .|.|.||  ... |.  .| |  .|..    ||.....|.| . .  . ||..|...|.|..||.. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

SH---------LIVGETSEESTVLN--VR-KQLLSVCLQVANGMNYLAS--QRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTKNYFNQFKES-KSVK
           |  .  ........  .  |.|.. . |.|.||.||||  ....||| .|||.|.....|.|..|||....|||    ..   . .. .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT---NGVYSMMCSQGR

LPVKWMALESLY--YGIF-SEKSDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAAC-SEDVYSLMQQCWRESPDDRPLFSDLVASV
.|..|||.|||.  .|.. ..||||||.|.| ||.|. |. |||||... ..|..  | |.  |  . | |...|.||..||...|..|| |....   
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQP--EHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase AqueK377.AA Src 381-655 36 4.6e-72 244.13 In-house 1-255 (255) Show / Hide
Range on Protein: 381-655
Range on HMM: 1-255/255
Sequence Identity: 36% (102 aa)

IDIQETIGQGEFGIVYKATIIMDKSRQEIALKTLKGAFSKSDVNSLLEECLLMSNFNNPNVLSLIGVCADLGSAPG-IILPYMSRGSLLSYLQKEKSHLI
|   . .||| || |....    . . . | |||| .    ... .|.|  .| ..  .....|  || .    |  |.  |||.|||| ||.|      
IKLCRKLGQGQFGEVWMGYW---NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEE--PIYIVTEYMSHGSLLDYLKK------

VGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTKNYFNQFKESKSVKLPVKWMALESLYYGIFSEK
    ..|   |... ||..   |||.||.|| |...|||| |||| |. .| | |||||||   .  ..  .    ..  |.|.||.| | . || |. |
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKED-DDEYCARHGAKFPIKWTAPEAINYGRFTIK

SDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAACSEDVYS-LMQQCWRESPDDRPLFSDLVASV
|||||.||| .|... |..|||||.    .. .. | |. ||||  | . .|  .|.|||...|..|| |  |    
SDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK377.AA Axl 381-653 35 8.1e-72 244.91 In-house 1-267 (267) Show / Hide
Range on Protein: 381-653
Range on HMM: 1-267/267
Sequence Identity: 35% (99 aa)

IDIQETIGQGEFGIVYKATIIMDK-SRQEIALKTLKGA-FSKSDVNSLLEECLLMSNFNNPNVLSLIGVCADLGS-----APGIILPYMSRGSLLSYLQK
. .  ..|.|||| |  . .  .  | . .| |..| . ...|..   | |   | .|. |||. |||||  . .     .| .|||.|  | | ..   
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTF---

EKSHLIVGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTKNYFNQFKESKSVKLPVKWMALESLYY
    |.     ..   | . . |.   . .| || ||....||||| |||||.....  . |||||||  .|   |. | . .   |.||||.|.|||  
----LLYSRLGDQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIA---KMPVKWIAIESLAD

GIFSEKSDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAACSEDVYSLMQQCWRESPDDRPLFSDLVA
 ..  |||||..|.  ||.   |. ||||..   . . | .|.||  |..  | ...| || |||.  | ||| || |  
RVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPED--CMDELYDLMYQCWEADPKDRPSFSVLRE

Kinase AqueK377.AA ALK 381-657 37 1.5e-68 234.02 In-house 1-273 (273) Show / Hide
Range on Protein: 381-657
Range on HMM: 1-273/273
Sequence Identity: 37% (108 aa)

IDIQETIGQGEFGIVYKATIIM---DKSRQEIALKTLKGAFSKSDVNSLLEECLLMSNFNNPNVLSLIGVCADLGSAPG-IILPYMSRGSLLSYLQKEKS
|.     |.| || || .  .    | .   .|.|||.   |. |    . | | |..|| .|| ..||.|  . ..|  |.| ||. | ..|.|     
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGIC--FQKQPYMIVLEYMEGGDMKSFLRECRP

HLIVGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNG---VIKVADFGLSEEV-YTKNYFNQFKESKSVKLPVKWMALESLY
|    . |   . | . | || .|. || |  || ...||||| ||||||    |   | |.|||| . .. |   |.   |  .   .|||||  | . 
H----PESLQPSQL-TMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYR--KGGRAM-MPVKWMPPEAFM

YGIFSEKSDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAACSEDVYSLMQQCWRESPDDRPLFSDLVASVNA
 |||  |.||||.|.||||.|| | .||||.  .   |..  | |.  | |  |   || .| |||.  | ||| | ... .  .
DGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY

Kinase AqueK377.AA Fer 381-656 29 1.9e-67 228.72 In-house 1-283 (283) Show / Hide
Range on Protein: 381-656
Range on HMM: 1-283/283
Sequence Identity: 29% (90 aa)

IDIQETIGQGEFGIVYKAT-----II---MDKSRQEIALKTLKGAFSKSD-VNSLLEECLLMSN-FNNPNVLSLIGVCADLGSAPGIILPYMSRGSLLSY
..... .| | ||.|||..     .    ...   ... |..|..... .  . .. |  .| | .. |||  ..|||.|   .  |.. ... |||.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDE-QPIMIVMEFCNGGSLDSY

LQKEKSHLIVGETSEESTVLNVRK-QLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIK---VADFGLSEE----VYTKN--YFNQFKESKSVK
|.|.|.              .|   ...  |.|.|.||.|| |.  |||| ||||||. ...| |   ..|||.| .    .|..           |. |
LKKNKNK-------------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE-------KACK

LPVKWMALESLYYGIFSEKSDVWSYGILCWEVFSAGKIPYPG----MDPTGL-----VELLDGGQRLSCPHNAACSEDVYSLMQ-QCWRESPDDRPLFSD
.|..|.| |.. .||.|.|.||||.|..|||.|. |. ||||    | .| .         ..| .. .| .  . ......|  ||| . |.||| ...
VPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNH--MPPEIMQIMMKQCWQKDPEDRPTMKE

LVASVN
..  ..
ICQKLK

Kinase AqueK377.AA Musk 381-655 34 2e-67 221.77 In-house 1-282 (282) Show / Hide
Range on Protein: 381-655
Range on HMM: 1-282/282
Sequence Identity: 34% (99 aa)

IDIQETIGQGEFGIVYKAT---IIMDKSRQEIALKTLKGAFSKSDVNSLLEECLLMSNFNNPNVLSLIGVCADLGSAPGIILPYMSRGSLLSYLQKEKSH
|     ||.| || |. |     . .     .| | ||   ||        |  .|  | .||.  | |||. .|      . ||. | |  .|.    |
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCF-VGRPMCLLFEYMAYGDLNEFLHSCSPH

LIVGETSEES-----------TVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTKNYFNQFKESKSVKLPVKWM
     |...              |.   | | .  |.| || ||   .|.||| | ||||| .. ..|.|||||| ..| ..|   .|  .    |. ||
RTCSRTHQDRGMRAQVSSPGPPQLKCYHQ-LCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDY---YKGHENDHIPIRWM

ALESLYYGIFSEKSDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAACSEDVYSLMQQCWRESPDDRPLFSDLVASV
..||..|  |.  ||||.||.. ||.|| .  || ||     .     | .|||| |  |  .|| || .||   | ||| | ..  ..
PPESIWYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPEN--CPQKVYQLMRRCWQKNPADRPFFCQIHHCI

Kinase AqueK377.AA Tec 381-657 36 7.3e-66 225.12 In-house 1-254 (254) Show / Hide
Range on Protein: 381-657
Range on HMM: 1-254/254
Sequence Identity: 36% (103 aa)

IDIQETIGQGEFGIVYKATIIMDKSRQEIALKTLK-GAFSKSDVNSLLEECLLMSNFNNPNVLSLIGVCADLGSAP-GIILPYMSRGSLLSYLQKEKSHL
. . . .|.| ||.|  .     ..  ..| |..| |. |  |    .||   | .   |.   | |||     .|  |.  ||..|.||.|| ..| |.
LTFMKELGSGQFGVVHLGKW---RHQYDVAIKMIKEGSMSEED---FIEEAKVMMKLSHPKLVQLYGVCSQ--QRPIYIVTEYMEHGCLLNYLREHKHHF

IVGETSEESTVLNVRKQ--LLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTKNYFNQFKESKSVKLPVKWMALESLYYGIF
.             ...  ||..|..|  || || .. ||||| ||||||. |..|.||.|||..  |    |      |   | |||| . | . |  .
Q-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTS----SVGTKFPVKWCPPEVFHYSRY

SEKSDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAACSEDVYSLMQQCWRESPDDRPLFSDLVASVNA
| |||||..|.| ||||| ||.||. |. .  ||    | ||  ||   ||. .|  | .||.|.|..|| |..|  ..  
SSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPH--LCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE

Kinase AqueK377.AA S_TKc 381-663 19 7.7e-33 116.34 SMART 1-231 (231) Show / Hide
Range on Protein: 381-663
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

IDIQETIGQGEFGIVYKATIIMDKSRQEIALKTLKGAFSKSDVNSLLEECLLMSNFNNPNVLSLIGVCADLGSAPGIILPYMSR--GSLLSYLQKEKSH-
 .| ..||.| || |||.. .   . .. |.| .|        .... |  .... . ||.  |..|. |  .   ... |..   |.|..|..| ..| 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LIVGETSEESTVLNVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVIKVADFGLSEEVYTKNYFNQFKESKSVKLPVKWMALESLYY
    .   ..              ... |......|. |...||||    | |. .  .||..||||. ..            ...     .|| | |  
LRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL--

GIFSE-KSDVWSYGILCWEVFSAGKIPYPGMDPTGLVELLDGGQRLSCPHNAACSEDVYSLMQQCWRESPDDRPLFSDLVA-SVNALIMPLA
  ..  |.|.|| |.. .| .. |. |.|  ..  . ...              |... .....|..  |..||   .. .  . . ..|  
-GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK377.AA Pkinase 381-552 24 2.3e-20 73.06 Pfam 1-166 (293) Show / Hide
Range on Protein: 381-552
Range on HMM: 1-166/293
Sequence Identity: 24% (46 aa)

IDIQETIGQGEFGIVYKATIIMDKSRQEIALKTLKGAFSKSDVNSLLE---ECLLMSNFNNPNVLSLIGVCADLGSAPGIILPYMSRG----SLLSYLQK
. | ..||.| || |||.  .  ..... |.|..|    ||...  .    |. .| ..| ||.. |.... | .. . ....|.  |    .| .|.. 
YHIGRKIGSGSFGCVYKC--HHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST

EKSHLIVGETSEESTVL--NVRKQLLSVCLQVANGMNYLASQRFIHRDFAARNCLIADNGVI----KVADFGLSEEVYTKNYFNQ
           ......     ... ....|.. |..|. |...||||    |.|| .||.|    |..||||.. ..   | |.
-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NN

Kinase AqueK377.AA Pkinase 577-655 14 1e-06 24.45 Pfam 190-293 (293) Show / Hide
Range on Protein: 577-655
Range on HMM: 190-293/293
Sequence Identity: 14% (16 aa)

SEKSDVWSYGILCWEVFSAGKIPYPGM----DPTGLVELLDGGQRLSCPHNAACS-----------------------EDVYSLMQQCWRESPDDRPLFS
. |.|.||.|....|... |. |.||     .     ....  .....|    ..                       |.  ...  |..  | .|| . 
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMIC--RIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

DLVAS--V
... .  .
QILQHPWF