Gene AqueK381 (A.queenslandica)

AqueK381

Species: A.queenslandica
Alias: AqueK381
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK381.AA Protein None 2055 None Fasta, JSON
AqueK381.kin_dom Protein Kinase Domain None 279 None Fasta, JSON

Protein domain

Protein domains of AqueK381.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Calx_beta AqueK381.AA Calx_beta 371-465 20 0.000561 1.13 SMART 1-106 (106) Show / Hide 
Range on Protein: 371-465
Range on HMM: 1-106/106
Sequence Identity: 20% (22 aa)

VGVTFYSIE-PLISSAPEN--------GLVSVTVYRSGD-VSEASSVQVGTFMSSKSNAAKIG-EDFENQ--TKTIQFAANE-FLATVNFTFIDDFFPEQ
. |. ..   . . .  .         | . |.| |.|.  ... .|.     .. .. |. |  |.| .    |..|...|   ..... .||| . | 
ATVMILDDDHMGTVFFEQPHYTVNENCGEFEVCVVRTGGTARGTVVVPY----RTQDGTATAGGSDYEPWDIPGTLTFPPGEGTMKCIRIKIIDDDIYEK

-DEVFDVKFI
 || | | . 
RDEHFYVRLS
Calx-beta AqueK381.AA Calx-beta 420-460 35 1.506977 4.5 Pfam 60-104 (109) Show / Hide 
Range on Protein: 420-460
Range on HMM: 60-104/109
Sequence Identity: 35% (16 aa)

AKIG--EDFENQTKT-IQFAANE-FLATVNFTFIDDFFPEQDEVF
|. |   |.| .. | ..| ..|    ..| | ||| . | || |
ATAGPGDDYEPTEGTILTFNPDEDTHKCINVTIIDDDIYEGDEHF
Calx-beta AqueK381.AA Calx-beta 545-590 23 0.097296 8.8 Pfam 60-109 (109) Show / Hide 
Range on Protein: 545-590
Range on HMM: 60-109/109
Sequence Identity: 23% (12 aa)

AQE---EDYDNTTIA-VIMPPGD-TEVCAHISTVEDRIFNEPNEEFCINVT
|..    ||  |.   ..  |.  |. |  .  ..| |. |..| | .. .
ATAGPGDDYEPTEGTILTFNPDEDTHKCINVTIIDDDIY-EGDEHFFVHLS
Calx_beta AqueK381.AA Calx_beta 644-745 20 0.000259 5.32 SMART 1-106 (106) Show / Hide 
Range on Protein: 644-745
Range on HMM: 1-106/106
Sequence Identity: 20% (23 aa)

AGFGMRPIG-VTFYSIEPLNSSAPES-GLVSVTVYRSGD-VSEASLVRVGTFLSSKSNAAMIG-EDLENQ--TKTIKFAANE-FSATVNFSFLSDSISEL
|   . .   ... ..|. . .  |. | . |.| |.|.  ...  |.     .. .. |. |  | | .    |. |...|   ..... .. |.| | 
ATVMILDDDHMGTVFFEQPHYTVNENCGEFEVCVVRTGGTARGTVVVPY----RTQDGTATAGGSDYEPWDIPGTLTFPPGEGTMKCIRIKIIDDDIYEK

-DEVFLVGFL
 || | | ..
RDEHFYVRLS
Calx-beta AqueK381.AA Calx-beta 700-742 31 4.744642 2.7 Pfam 60-106 (109) Show / Hide 
Range on Protein: 700-742
Range on HMM: 60-106/109
Sequence Identity: 31% (15 aa)

AMIG--EDLENQTKT-IKFAANE-FSATVNFSFLSDSISELDEVFLV
|. |   | | .. | . | ..|    ..|   . |.| | || | |
ATAGPGDDYEPTEGTILTFNPDEDTHKCINVTIIDDDIYEGDEHFFV
Calx_beta AqueK381.AA Calx_beta 760-863 22 0.000329 4.02 SMART 1-106 (106) Show / Hide 
Range on Protein: 760-863
Range on HMM: 1-106/106
Sequence Identity: 22% (25 aa)

LTILGVDSN---IVKFTADNYCVHEGNTSVYVCVEKSRD-TTDSLKLEITAMEDATQSAAEDI-FDFVAE--TKTITFLGSS-PQVCVQFQIIQDPFFDF
.|.  .|..   .| |.  .| | |.  ...|||..... ..      ..  ..     | .   |...     |.||      . |... || |   |.
ATVMILDDDHMGTVFFEQPHYTVNENCGEFEVCVVRTGGTARGTVVVPYRTQDG----TATAGGSDYEPWDIPGTLTFPPGEGTMKCIRIKIIDD---DI

KEP-LETFYVNFT
 |   |.||| ..
YEKRDEHFYVRLS
Calx-beta AqueK381.AA Calx-beta 815-863 26 1.075066 5.03 Pfam 60-109 (109) Show / Hide 
Range on Protein: 815-863
Range on HMM: 60-109/109
Sequence Identity: 26% (14 aa)

AEDI--FDFVAETKT-ITFLGSS-PQVCVQFQIIQDPFFDFKEPLETFYVNFT
|..    |... . | .||      . |.  .|| |   |. |. |.|.|. .
ATAGPGDDYEPTEGTILTFNPDEDTHKCINVTIIDD---DIYEGDEHFFVHLS
Calx-beta AqueK381.AA Calx-beta 939-984 28 0.001767 15.09 Pfam 60-109 (109) Show / Hide 
Range on Protein: 939-984
Range on HMM: 60-109/109
Sequence Identity: 28% (14 aa)

AKSG--SDFVAEIID-VPFTSDD-LRVCATFMIINDDIVEKNESFLITVI
|. |  .|...   . . |  |   . |    ||.|||.|..| | .   
ATAGPGDDYEPTEGTILTFNPDEDTHKCINVTIIDDDIYEGDEHFFVHLS
Calx-beta AqueK381.AA Calx-beta 995-1063 29 0.0033 14.11 Pfam 1-71 (109) Show / Hide 
Range on Protein: 995-1063
Range on HMM: 1-71/109
Sequence Identity: 29% (22 aa)

IKITITDEDDAAVIKFSNDTYTFP-ENIDMDAQVCVETTKA---LSDDISINFRTRSSDVNGAATAV--LDYISK
. .|| |.||| || |.. .|.   .. .  ..|||. .     |. . ....||    ..| |||    ||...
ATVTILDDDDAIVIGFEPTHYQVDVNENCGTVEVCVVRMGGAPTLRRTVTVMYRT----EDGTATAGPGDDYEPT
GPS AqueK381.AA GPS 1584-1632 54 2.4e-16 61.04 Pfam 1-49 (49) Show / Hide 
Range on Protein: 1584-1632
Range on HMM: 1-49/49
Sequence Identity: 54% (27 aa)

SFPQCVFWDQSLNSGYGDWSSDNCDT-SYDSVTQAIKCFCNHLTSFAVIQ
. ||||||| |||.| |.||.| | .  . . |. ..| |||||||||. 
YNPQCVFWDFSLNEGMGGWSTDGCRVGVHTNHTH-THCQCNHLTSFAVLM
GPS AqueK381.AA GPS 1584-1637 38 1.9e-13 51.92 SMART 1-51 (51) Show / Hide 
Range on Protein: 1584-1637
Range on HMM: 1-51/51
Sequence Identity: 38% (21 aa)

SFPQCVFWDQSLNSGYGDWSSDNCDTSYDSV-TQAIKCFCNHLTSFAVIQDVSPT
. |.||.|..|     | ||. .| ... .  |... | |||||.|||. |..| 
FNPICVWWNHSQ---TGHWSTRGCEVVETNKWTHTH-CQCNHLTTFAVLMDHPPN
Pkinase_Tyr AqueK381.AA Pkinase_Tyr 1762-2040 38 9.1e-108 365.61 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1762-2040
Range on HMM: 1-270/270
Sequence Identity: 38% (110 aa)

INLQEAVGQGEFGIVYRALLA-TGKDVPQVVAVKTLKGLFSRSD--VASIVEESLIMSNF-DHPNVLSLIGVSLDLGPA--PCIIMPFMSRGSLLSYLKN
| . .  |.|.|| ||.. .   ...  . ||||.||   . ..   ..  .|  ||... .|||...|.|| .| |    ..|.|..|  |.||.||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

DRLNITITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTKTYF-NQFKDKNEAESVKLPIKWMAIE
 |         ...  |..   ||..|.|.|.|| ||.|. ..|||||||||....|.|.|..||||.  .| . |   .      ... |||||||| |
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRK------RGGGKLPIKWMAPE

SIHDGIFSEKSDVWSYGVLCWEVFNGGKTP-FPGLDPAGVIQLL-DTGGRLNYPHNDACSDTIYELMLSCWYESPNDRPLFSELNTSI
.|..|.|..||||||.|||.||.|  |..| .||.... |.... . |.|.  |.|  |.| ||.||..|| . |.||| |||.   .
CINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK381.AA TyrKc 1762-2040 35 3.2e-104 353.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 1762-2040
Range on HMM: 1-280/280
Sequence Identity: 35% (110 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLK-GLFSRSDVASIVEESLIMSNF--DHPNVLSLIGVSLDLG------PAPCIIMPFMSRGSLLSY
| | .  | |.||.||.. .       . ||||.|| .      .. . .|  ||...  .|||.. |.|| .. |      . ..|.| .|. |.|..|
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LKNDRLNITITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTK---TYFNQFKDKNEAE--SVK--
|.. | .            |.. |.|||.|.|.|.|| ||.|. ..|||||||||....|...|..||||| ..| .         . .  .|  . |  
LRKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTM

LPIKWMAIESIHDGIFSEKSDVWSYGVLCWEVFNGGKTPFPG-----LDPAGVIQLLDTGGRLNYPHNDA------CSDTIYELMLSCWYESPNDRPLFS
|||.|||.|.| .|.|..||||||.||..||.|  |..| ||     .... ||.....|.|.  |.||       |.| .|..|..|| | |.||| ||
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

ELNTSI
|.   .
EIHECF
Kinase AqueK381.AA TK 1762-2040 22 1.1e-93 314.48 In-house 1-486 (486) Show / Hide 
Range on Protein: 1762-2040
Range on HMM: 1-486/486
Sequence Identity: 22% (109 aa)

INLQEAVGQGEFG---IVYRALLAT----------------------GKDVPQVVAVKTLKGLFSRSDVA----------------SIVEESLIMSN--F
| | .  |.|.||    ||.... .                      ...... ||||.||   . |. .                . .||  .|..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHPNVLSLIGVSLDLG-----------PAPCIIMPFMSRGS----LLSYLKNDRLNITI----------------------------TDGKDEEIILNV-
.|||...|.||... .           . ..|.| .|. |.    |..||.. | . .                             .. .... . .  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

--------------RKHLLS-------------------ICLQVANGMCYLASQ------YFVHRDLAARNCMIDNNGV-----------IKVADFGLS-
               |.||.                   .|.|.|.|| ||.|.       |||||||||||....|.|           .|.|||||| 
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

------------EEVYTKTY----------FNQFKDKNEAE----------SVKLPIKWMAIESIHDGI---------FSEKSDVWSYGVLCWEVFNGGK
            .. |...           |       .            . ||||.||| |.. |..         |..||||||.|||.||.|  |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFE------D-DPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQ

TPFPG-LDP---------AGVIQLLDTGGRL----------NYPHN--DACS--------------DTIYELMLSCWYESPNDRPLFSELNTSI
.|..| ..          . |...| .||||           ..    . |.              . .|.||..|| . |.||| ||.|   .
EPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK381.AA Met 1763-2034 36 1.7e-90 296.88 In-house 1-271 (271) Show / Hide 
Range on Protein: 1763-2034
Range on HMM: 1-271/271
Sequence Identity: 36% (106 aa)

NLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLK--GLFSRSDVASIVEESLIMSNFDHPNVLSLIGVSLDLGP-APCIIMPFMSRGSLLSYLKNDRLN
 . . .||| || ||.. .  ..     .|.|.|.         .    .| ..|. |||||||||||..||     | .. |.|  | |... .|   |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

ITITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEV-YTKTYFNQFKDKNEAESVKLPIKWMAIESIH-
...             . |.. |.||| || |.||| |||||||.||||.|   ..|||||||.  . | | |  |   ...    .||.|||| |.   
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQ---MHHTHPARLPVKWMAPECLQQ

-------DGI-FSEKSDVWSYGVLCWEVFNGGKTPFPGLDP-AGVIQLLDTG--GRLNYPHNDACSDTIY-ELMLSCWYESPNDRPLFS
       . . |. |||||| ||. || .  | .| |  |.   .   | .|   ||  |    | | .| ..||.||  .| ||| ||
GVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEY--CPDHLYTDVMLCCWHANPEDRPQFS
Kinase AqueK381.AA UTK 1762-2040 32 3e-87 296.15 In-house 1-296 (296) Show / Hide 
Range on Protein: 1762-2040
Range on HMM: 1-296/296
Sequence Identity: 32% (100 aa)

INLQEAVGQGEFGIVYRALLATGK--DVPQVVAVKTLK-GLFSRSDVA---SIVEESL---IMSNFD-HPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLS
. | .  |||.||.|..| . . .     ..||||... . ... . .    . ||.    .|..|. ||||| |.|| .. .| ..|.. .|..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLKNDRLNITITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNG-------VIKVADFG---LSEEVYTKTYFNQFKDKNEA
|| . | .       ... .|. . ..|. ....|.|| ||.|. ||||||||||| .. ..       |.|.||||   .| .|.| . |   ....  
YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH-FSN-RYWESY

ESVK-----LPIKWMAIESIHDG-IFSEKSDVWSYGVLCWEVFNGGKTPFPGLDPAGVIQLLDTGGRLNYPHNDACSDTIYELMLSCWYESPNDRPLFSE
.. .     .||.||| |.. ..  |..||||||.||.|||.. .|..|.||.  . |.. .  |||.  | ...|....|.||..||. .| .|| | .
YYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFED

LNTSI
|   .
LVQQM
Kinase AqueK381.AA TK-Unique 1762-2040 31 1.2e-83 284.24 In-house 1-294 (294) Show / Hide 
Range on Protein: 1762-2040
Range on HMM: 1-294/294
Sequence Identity: 31% (94 aa)

INLQEAVGQGEFGIVYRALLATGK---DVPQVVAVKTLKGLFSRSDVASIVEESLIMSNFD-HPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKNDR
..... .|.|.|| |.|. . ...   | ...||||.||  ..  |..    |  .|.. . |||.....|.. . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-L--------NITITDGKDEEIILN--VR-KHLLSICLQVANGMCYLAS--QYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTKTYFNQFKDKNEAES
          |. .. . .... ..  .  | |.... |.|.|| ||||  . .|||||.|||... ...|.|..|||....|||       .  .. ..
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-----NGVYSMMCSQ

VKLPIKWMAIESIH--DGIF-SEKSDVWSYGVLCWEVFNGGKTPFPGLDPAGVIQLLDTGGRLNYPHNDAC-SDTIYELMLSCWYESPNDRPLFSELNTS
 ..||.||| ||.   .|.. ..||||||.||| ||.|  |..|.||.... .....  | |.. |  . | |...|.|| ||| ..| .|| |...   
GRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQP--EHCCSHEMYNLMKSCWQWEPEERPSFRQIKHR

I
.
L
Kinase AqueK381.AA Axl 1762-2038 38 2.5e-74 253.27 In-house 1-267 (267) Show / Hide 
Range on Protein: 1762-2038
Range on HMM: 1-267/267
Sequence Identity: 38% (108 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLK-GLFSRSDVASIVEESLIMSNFDHPNVLSLIGVSLDLG-----PAPCIIMPFMSRGSLLSYLKN
. |   .|.|||| |  . |       . ||||..|   ...|..   . |   | .||||||. ||||.. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

DRLNITITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTKTYFNQFKDKNEAESVKLPIKWMAIES
 ||.       |. . | . . |.   . .| || ||... |.||||||||||. ..  . |||||||  .|   |. |          |.|.||.||||
SRLG-------DQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQ------GCIAKMPVKWIAIES

IHDGIFSEKSDVWSYGVLCWEVFNGGKTPFPGLDPAGVIQLLDTGGRLNYPHNDACSDTIYELMLSCWYESPNDRPLFSELNT
. | ..  |||||..||  ||.   |.||.||.. . . . |  | ||  |..  | | .|.|| .||   | ||| ||.|  
LADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPED--CMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK381.AA Src 1762-2040 36 4.3e-67 226.96 In-house 1-255 (255) Show / Hide 
Range on Protein: 1762-2040
Range on HMM: 1-255/255
Sequence Identity: 36% (104 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLKGLFSRSDVASIVEESLIMSNFDHPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKNDRLNIT
| | .  ||| || |. ..    . ..  |||||||      ...   .|  || ...|.....|  |  .  |   |.  .||.|||| |||.      
IKLCRKLGQGQFGEVWMGYWN--GNTK--VAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK------

ITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVY--TKTYFNQFKDKNEAESVKLPIKWMAIESIHDG
    ..|.  |... .|...  |||.||.|| |. ..||||||||  ...| | |||||||   .      |  .          |.||||.| | |. |
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH-------GAKFPIKWTAPEAINYG

IFSEKSDVWSYGVLCWEVFNGGKTPFPGLDPAGVIQLLDTGGRLNYPHNDACSDTIYE-LMLSCWYESPNDRPLFSELNTSI
 |. ||||||.|.| .|..  |..| || . . |.| .. | |.  |||  | | .|| .|| || ..| .|| |  |.   
RFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK381.AA Fer 1762-2041 29 1.1e-66 226.14 In-house 1-283 (283) Show / Hide 
Range on Protein: 1762-2041
Range on HMM: 1-283/283
Sequence Identity: 29% (92 aa)

INLQEAVGQGEFGIVYRA------LLATGKD-VPQVVAVKTLKGLFSRSD-VASIVEESLIMSN-FDHPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSY
..|..  | | ||.||..      ..... . ..  |.||..|. ... .  . .  |  || | .|||||  ..||. |  |   |.| |.. |||.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPI-MIVMEFCNGGSLDSY

LKNDRL-NITITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIK---VADFGLSEE----VYTKT--YFNQFKDKNEAE
||     ....             . .. .|.|.|.|| || |.  .|||.||||| .....| |   ..|||.| .    .|...             .
LKKNKNKTVSD-------------NEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE----------K

SVKLPIKWMAIESIHDGIFSEKSDVWSYGVLCWEVFNGGKTPFPG----LDPAGV--IQLLD-TGGRLNYPHNDACSDTIYELML-SCWYESPNDRPLFS
. |.||.|.| |.. .||.|.|.||||.||.|||.|. |..|.||    . .. |   .    . ..   |. . . ..|...|. .|| . |.||| ..
ACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMK

ELNTSIN
|.   ..
EICQKLK
Kinase AqueK381.AA ALK 1762-2042 36 1.9e-66 227.07 In-house 1-273 (273) Show / Hide 
Range on Protein: 1762-2042
Range on HMM: 1-273/273
Sequence Identity: 36% (106 aa)

INLQEAVGQGEFGIVYRALLAT--GKDVPQVVAVKTLKGLFSRSDVASIVEESLIMSNFDHPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKNDRLN
| |  | |.| || || ..     |  ||  ||.|||. . |. |      | |||..|.|.|| ..||....  |   |.  .|. | ..|.|.  | .
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH

ITITDGKDE--EIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNG---VIKVADFGLSEEV-YTKTYFNQFKDKNEAESVKLPIKWMAI
        |     . . | || .|. || |  || .. |.||| |||||     |   | |.|||| . .. |   |.             .|.|||  
-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRK------GGRAMMPVKWMPP

ESIHDGIFSEKSDVWSYGVLCWEVFNGGKTPFPGLDPAGVIQLLDTGGRLNYPHNDACSDTIYELMLSCWYESPNDRPLFSELNTSINA
|   ||||  |.||||.||||||.|  |  |.||     |.... .|||...| |  |   .| .|  ||   | ||| |  .  .| .
EAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK381.AA HMTK 1944-2039 42 1.3e-35 121.67 In-house 192-291 (291) Show / Hide 
Range on Protein: 1944-2039
Range on HMM: 192-291/291
Sequence Identity: 42% (42 aa)

VKLPIKWMAIESIH--DGIFSEKSDVWSYGVLCWEVFNGGKTPFP--GLDPAGVIQLLDTGGRLNYPHNDACSDTIYELMLSCWYESPNDRPLFSELNTS
|||||||||.|     ..|||||||||..||..||..  | .|..  ..    |   .  |.||  |  |.|.| ...|| .||   |. || |..|  .
VKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
Kinase AqueK381.AA S_TKc 1762-2044 19 4.1e-34 120.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 1762-2044
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLKGLFSRSDVASIVEESLIMSNFDHPNVLSLIGVSLDLGPAPCIIMPFMSR--GSLLSYLKNDRLN
  . . .|.| || ||..         ..||.| .|         .|  |  |... .|||.  |..|  |     ...| ...   |.|..|.|. . .
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----ITITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLSEEVYTKTYFNQFKDKNEAESVKLPIKWMAIE
     ..  .               ... |..... |. |. ..||||   | ..|.  .||..||||. ..                ..     .|| |
GLRFPFPE-H-------------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPE

SIHDGIFSE-KSDVWSYGVLCWEVFNGGKTPFPGLDPAGVIQLLDTGGRLNYPHNDACSDTIYELMLSCWYESPNDRPLFSELNTSI-----NALI
 .    ..  |.|.|| |.. .| .  |..|||  ... .....              |.   ...  |.   |..||   |. ..         .
VL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK381.AA Tec 1945-2042 42 3.6e-31 106.2 In-house 159-254 (254) Show / Hide 
Range on Protein: 1945-2042
Range on HMM: 159-254/254
Sequence Identity: 42% (42 aa)

KLPIKWMAIESIHDGIFSEKSDVWSYGVLCWEVFNGGKTPFPGLDPAGVIQLLDTGGRLNYPHNDACSDTIYELMLSCWYESPNDRPLFSELNTSINA
| |.|| . |  |   .| |||||..||| |||| .|| |.. ..   |..   .| ||  ||   ||..||. | .|| |.| .|| |..|  .|  
KFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPH--LCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK381.AA Tec 1762-1923 32 2.6e-30 103.12 In-house 1-144 (254) Show / Hide 
Range on Protein: 1762-1923
Range on HMM: 1-144/254
Sequence Identity: 32% (53 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLK-GLFSRSDVASIVEESLIMSNFDHPNVLSLIGVSLDLGPAPCIIMPFMSRGSLLSYLKNDRLNI
. . . .|.| ||.| .. .    |    ||.|..| |  |  |    .||  .| .  ||.   | || .   |  .|.  .|..|.||.||.  .   
LTFMKELGSGQFGVVHLGKWRHQYD----VAIKMIKEGSMSEED---FIEEAKVMMKLSHPKLVQLYGVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHF

TITDGKDEEIILNVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLS
       ..  .     ||..|..|  || || .. |.||||||||| .. ..|.||.|||..
Q------KNMAI-----LLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMT
Kinase AqueK381.AA Pkinase 1762-1934 24 1.3e-24 88.06 Pfam 1-166 (293) Show / Hide 
Range on Protein: 1762-1934
Range on HMM: 1-166/293
Sequence Identity: 24% (46 aa)

INLQEAVGQGEFGIVYRALLATGKDVPQVVAVKTLKGLFSRSDVASIVE---ESLIMSNFDHPNVLSLIGVSLDLGPAPCIIMPFMSRG----SLLSYLK
. . . .|.| || ||..      .   .||||..|    .|..  .     |  || ...|||.. |...  | .. ....|...  |    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

NDRLNITITDGKDEEIIL--NVRKHLLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVI----KVADFGLSEEVYTKTYFNQ
            ...  .     ... ....|.. |. |. |. ..||||   |..|||||.|    |..||||.. ..   | |.
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NN
Kinase AqueK381.AA HMTK 1878-1923 56 5.3e-20 66.51 In-house 130-175 (291) Show / Hide 
Range on Protein: 1878-1923
Range on HMM: 130-175/291
Sequence Identity: 56% (26 aa)

LLSICLQVANGMCYLASQYFVHRDLAARNCMIDNNGVIKVADFGLS
.|..| |.| || |.||| .||.|||||||..  | ..|.|||||.
QLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLT
Kinase AqueK381.AA Pkinase 1962-2040 17 2.2e-11 41.31 Pfam 190-293 (293) Show / Hide 
Range on Protein: 1962-2040
Range on HMM: 190-293/293
Sequence Identity: 17% (19 aa)

SEKSDVWSYGVLCWEVFNGGKTPFPGL----DPAGVIQLLDTGGR--LNYPHNDACS-------------------DTIYELMLSCWYESPNDRPLFSEL
. |.|.||.|....|... |..||||     . .  .|...  ..  | ..    ||                   ..  ... .|.   |..|| . ..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

NTS--I
  .  .
LQHPWF
Kinase AqueK381.AA HMTK 1762-1831 24 7e-11 34.27 In-house 1-94 (291) Show / Hide 
Range on Protein: 1762-1831
Range on HMM: 1-94/291
Sequence Identity: 24% (23 aa)

INLQEAVGQGEFG-----------------IVYRALLA-------TGKDVPQVVAVKTLKGLFSRSDVASIVEESLIMSNFDHPNVLSLIGVSL
.  . . |.| ||                  || |...       .. . |. .|||.|.|  |  | .    |.  |....|||...|.||..
LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCM