AqueK385

Species: A.queenslandica
Alias: AqueK385
External Links:
Annotation:

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
AqueK385.AA Protein None 778 None Fasta, JSON
AqueK385.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of AqueK385.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SR AqueK385.AA SR 59-160 39 2.9e-44 154.29 SMART 1-118 (118) Show / Hide
Range on Protein: 59-160
Range on HMM: 1-118/118
Sequence Identity: 39% (47 aa)

IRLVDGNGPNEGRLEICING----DWGTVCDDKWSHTNAQVVCRQLGYSTDGAVFLE----KAFFGAGNGSILLDEVECSGSEDTILQCMHNSFGSHD--
.|||.||.|.|||.|. .||     ||||||| |. ..|.|||||||...  ..  .     |.||.|.| |..|.| |.|.|... .|.|...|.|.  
VRLVGGNNPCEGRVEVYHNGGGQGQWGTVCDDNWDIRDANVVCRQLGCGGAVSASQTLPATWAHFGQGSGPIWMDNVRCTGTETSLWDCPHWGWGQHNNC

CGH------HEDVVTIED
|.|      .||.  .  
CSHNHHRNRQEDAGVVCS

SRCR AqueK385.AA SRCR 62-155 42 3.2e-37 126.86 Pfam 1-107 (112) Show / Hide
Range on Protein: 62-155
Range on HMM: 1-107/112
Sequence Identity: 42% (45 aa)

VDGNGPNEGRLEICI-NGDWGTVCDD-K-WSHTNAQVVCRQLGYSTDGAVF-LEKAF--FG--AGNGSILLDEVECSGSEDTILQCMHNSFGS--HD--C
|.|..|.|||.|..  || |||||||   |. ..|.|||||||.  ...      |.  ||  .|.| |..|.|.|.|.|... || | . |   |.  |
VGGSSPCEGRVEVRYHNGQWGTVCDDDGNWDMRDAHVVCRQLGCGGGAVQAWSCCAYAWFGNCPGTGPIWMDNVRCHGNETSLWQCPHSPWGWHRHNPMC

GHH-EDV
.|. ||.
SHSREDA

Pkinase_Tyr AqueK385.AA Pkinase_Tyr 470-751 38 1.8e-114 388.33 Pfam 1-270 (270) Show / Hide
Range on Protein: 470-751
Range on HMM: 1-270/270
Sequence Identity: 38% (112 aa)

IEIQETVGQGEFGIVYRGVMT-SNTQMPKAVAVKTLKGFYKESD--IDSLLDECIIMMSF-DNLNVLPLIGVCLDLGPA--PYIIMPFMSRGSLLSYLKK
|.. .. |.|.|| ||.|... .  .    ||||.||  . ...  ..... |  ||... .. |.. |.|||.| |    .||.|..|  |.||.||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

ERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYACNYFRQLKGSDN-NSGSSTVKLPVKWM
 |         |..  |..   ||..|.|.|.||.||. ...||||||||||....|.|.|..||||. ||         . .    .....  ||.|||
HR---------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--------YNDDYYYRKRGGGK-LPIKWM

ALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVP-YPGLDPIGVVELL-DTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSDLVSSI
|.|....| |..||||||.|||.||.|..|. | |||...  |.|.. . |.|. || |  |..|||.||..|| . | ||| ||.... .
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

TyrKc AqueK385.AA TyrKc 470-751 35 2.2e-113 383.91 SMART 1-280 (280) Show / Hide
Range on Protein: 470-751
Range on HMM: 1-280/280
Sequence Identity: 35% (111 aa)

IEIQETVGQGEFGIVYRGVMTSNTQMPKAVAVKTLKGFYKESDIDSLLDECIIMMSF--DNLNVLPLIGVCLDLG------PAPYIIMPFMSRGSLLSYL
|.  .. | |.||.||.|...        ||||.||       .  ...|  ||...  .. |.. |.|||.. |      . ..|.| .|. |.|..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYAC-------NYFRQLKGSDNNSGSST
.| ||.            |.. |.|||.|.|.|.||.||. ...||||||||||....|...|..||||| |||          | |. ..       . 
RKHRPK------------LCM-KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH-------KG

VK--LPVKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPG-----LDPIGVVELLDTGGRLQCPYNGA------CSQEIYSLMMLCWSESPIDR
 |  ||..|||.|.. .| |..||||||.||..||.|..|. ||||     .... |.|....|.|. .| |.       |..|.|..|  || | | ||
GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR

PVFSDLVSSI
| ||.... .
PTFSEIHECF

Kinase AqueK385.AA TK 470-751 22 3e-95 319.78 In-house 1-486 (486) Show / Hide
Range on Protein: 470-751
Range on HMM: 1-486/486
Sequence Identity: 22% (111 aa)

IEIQETVGQGEFG---IVYRGVMTSN----------------------TQMPKAVAVKTLKGFYKESDIDSLL---------------DECIIMMS---F
|.. .. |.|.||    ||.| . .                       .. .  ||||.||    .|. . ..                | . ||.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DNLNVLPLIGVCLDLG-----------PAPYIIMPFMSRGS----LLSYLKKERP-----------------------------NLTVADTSEEDIILNV
.  |.. |.|||.. .           . ..|.| .|. |.    |..||.| ||                             ..  .. .... . . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY-SHESNSPC-PEEQ

---------------RKQLLS-------------------ICLQVANGMSYLALQ------KFIHRDLAARNCMIDNNGV-----------IKVADFG--
                |.||.                   .|.|.|.||.||. .      .|.|||||||||....|.|           .|.||||  
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSEDIY-------------ACNYFRQLKGSDNNSGSS--------------TVKLPVKWMALESLHDGL---------FSEKSDVWSYGVLCWE
      |. |||             .... .           .                |||..||| |.| |.          |..||||||.|||.||
RQGSGVLARDIYSDDDYYRKSSYGTGRPM-W-----------PFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWE

VFSLGKVPYPGLDPI----------GVVELLDTGGR------------LQCPYNGACS--------------QEIYSLMMLCWSESPIDRPVFSDLVSSI
.|..|..||.|  .            |.|.| .|||            ...|    |.              .|.| ||. ||.. | ||| ||.|.. .
IFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL





Kinase AqueK385.AA Met 471-745 37 1.6e-90 297.0 In-house 1-271 (271) Show / Hide
Range on Protein: 471-745
Range on HMM: 1-271/271
Sequence Identity: 37% (110 aa)

EIQETVGQGEFGIVYRGVMTSNTQMPKAVAVKTLK--GFYKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGP-APYIIMPFMSRGSLLSYLKKERPN
   . .||| || ||.| .. | .    .|.|.|.      .  |   | | |.|  ||  ||| |||.|||     |... |.|  | |... . .  |
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

LTVADTSEEDIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDI-YACNYFRQLKGSDNNSGSSTV--KLPVKWMAL
..|             ..|.. |.||| ||.|.| |||.|||||.||||.|   ..|||||||. |. |   |  |         . |   .|||||||.
PCV-------------RDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQM--------HHTHPARLPVKWMAP

ESLH--------DGL-FSEKSDVWSYGVLCWEVFSLGKVPYPGLDP-IGVVELLDTG--GRLQCPYNGACSQEIY-SLMMLCWSESPIDRPVFS
|.|         .   |. |||||| ||. || .  | .|||  |. . .   | .|   ||  |    |   .|  .|  ||. .|.||| ||
ECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEY--CPDHLYTDVMLCCWHANPEDRPQFS

Kinase AqueK385.AA TK-Unique 470-751 33 4.8e-88 298.8 In-house 1-294 (294) Show / Hide
Range on Protein: 470-751
Range on HMM: 1-294/294
Sequence Identity: 33% (100 aa)

IEIQETVGQGEFGIVYRGVMTSNT---QMPKAVAVKTLKGFYKESDIDSLLDECIIMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
.|.....|.|.|| |.|| .....     .| ||||.||    . | . .|.|  .|.. .   |.. ..|.| . .  ..|||.....|.|..||.. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P---------NLT-VADTSEEDIILN-VR-KQLLSICLQVANGMSYLAL--QKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYACNYFRQLKGSDNNSG
|         ||   ... ...  .. .  |.|.... |.|.||.|||   .|..||||.|||... ...|.|..|||...|.|.        . .... 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT--------NGVYSMM

SSTVKLPVKWMALESLH--DGLF-SEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSDLV
 |  ..|..|||.|||   .| . ..||||||.||| ||.|.||. ||||...  ..|..  | |.. | .. ||.|.|.||  ||...| .|| |....
CSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQP-EHCCSHEMYNLMKSCWQWEPEERPSFRQIK

SSI
. .
HRL

Kinase AqueK385.AA UTK 470-751 32 1.6e-85 290.45 In-house 1-296 (296) Show / Hide
Range on Protein: 470-751
Range on HMM: 1-296/296
Sequence Identity: 32% (99 aa)

IEIQETVGQGEFGIVYRGVMTSNT-QMPK-AVAVKTLK-GFYKESDID---SLLDECI---IMMSFD-NLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLS
... .. |||.||.|...  |  . .|.. .||||... .  .. . .    .. |.    .|. |.   ||| |.|||.. .| ..|.. .|..|.|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

YLKKERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNG-------VIKVADFG---LSEDIY----ACNYFRQLKG
|| . ||..      ... .|. . |.|. ....|.||.||. ..|.||||||||| .. ..       |.|.||||   .| ...    .     . ..
YLRRHRPTPP-----ACPHWLTLH-QRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSN----RYWE

SDNNSGSSTVKLPVKWMALESLHDG-LFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVF
|.    ..  ..|..||| |.| ..  |..||||||.||.|||... |..||||.    |.. .  |||.. | . .|. ..| ||. ||  .| .|| |
SYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDF

SDLVSSI
 |||. .
EDLVQQM

Kinase AqueK385.AA ALK 470-753 38 4.8e-72 245.65 In-house 1-273 (273) Show / Hide
Range on Protein: 470-753
Range on HMM: 1-273/273
Sequence Identity: 38% (112 aa)

IEIQETVGQGEFGIVYRGVMTS--NTQMPKAVAVKTLKGFYKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPN
|.     |.| || || |  .   .   | .||.|||.   .. |    . |  ||  |.  ||  .||.|..  |  .|.  .|. | ..|.|.  ||.
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPY-MIVLEYMEGGDMKSFLRECRPH

LTVADTSEE--DIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNG---VIKVADFGLSEDI-YACNYFRQLKGSDNNSGSSTVKLPVKW
       .|     . . | || .|. || |  ||  ..||||| |||||     |   | |.|||| . || |   |.|         |  .  .||||
-------PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRK--------GGRAM-MPVKW

MALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSDLVSSINN
|  | . ||.|  |.||||.||||||.|||| .||||     | |.. .|||.  |.|  | | .| .|  ||   | ||| | ... .|  
MPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY

Kinase AqueK385.AA Axl 470-749 38 3.3e-71 242.86 In-house 1-267 (267) Show / Hide
Range on Protein: 470-749
Range on HMM: 1-267/267
Sequence Identity: 38% (110 aa)

IEIQETVGQGEFGIVYRGVMTSNTQMPKAVAVKTLK-GFYKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLG-----PAPYIIMPFMSRGSLLSYLKK
. .  ..|.|||| |  | .  .      ||||..|     .|.|.  | | . |  ||  ||. |||||. .      |.| .|.|||  | | ..|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

ERPNLTVADTSEEDIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWMA
 |         .. . | . . |.   . .| || ||. ..||||||||||||. ..  . |||||||  ||.  |.|| .           |.||||.|
SR-------LGDQPFYLPL-QMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGC---------IAKMPVKWIA

LESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSDLVS
.||| | ..  |||||..||  ||.   |. ||||..   . . |  | ||. | .  | .|.| ||  ||.  | ||| || |  
IESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPED--CMDELYDLMYQCWEADPKDRPSFSVLRE

Kinase AqueK385.AA Src 470-751 38 8.8e-71 239.7 In-house 1-255 (255) Show / Hide
Range on Protein: 470-751
Range on HMM: 1-255/255
Sequence Identity: 38% (109 aa)

IEIQETVGQGEFGIVYRGVMTSNTQMPKAVAVKTLKGFYKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNLT
|   .  ||| || |. |.   ||.    |||||||      . . .| |  || ...  ... |  || .  |  ||.  .||.|||| ||||      
IKLCRKLGQGQFGEVWMGYWNGNTK----VAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPI-YIVTEYMSHGSLLDYLKK------

VADTSEEDIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYACNYFRQLK-GSDNNSGSSTVKLPVKWMALESLH
    ..|   |... ||...  |||.||.||  ...|||||||||  ...| | |||||||          | .| . |. . ..  |.|.||.| | ..
----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLA---------RLIKEDDDEYCARHGAKFPIKWTAPEAIN

DGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPYNGACSQEIYS-LMMLCWSESPIDRPVFSDLVSSI
 | |. ||||||.|.| .|... |.||||| .   |.. .. | |. || |  | .|.|  .|. || ..| .|| |  | .  
YGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK385.AA InsR 470-753 34 7.8e-70 233.71 In-house 1-278 (278) Show / Hide
Range on Protein: 470-753
Range on HMM: 1-278/278
Sequence Identity: 34% (101 aa)

IEIQETVGQGEFGIVYRG----VMTSNTQMPKAVAVKTLKGFYKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKER
|..    ||| || || |    ..  .     ..|.||..      .    | |  .|  |.  .|  | |||    |. |..| .| .| | |||   |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPM-YVVMEMMTYGDLKSYLRSRR

PNLTVADTSEEDII----LNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYACNYFRQLKGSDNNSGSSTVKLPVKW
|        . ...       . |...   ... ||.|||  ||.|||||.||||..  . .|..|||.  |||   | |  ...         .||| |
PEEEF---NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKG---------MLPVRW

MALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELL-DTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSDLVSSINN
|| ||| || |. .|||||.||. ||. .||  || ||    | .     |. |. | |  |..  . ||| ||  .| .|| | |..... .
MAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPEN--CPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD

Kinase AqueK385.AA FGFR 470-751 34 7e-68 230.44 In-house 1-293 (293) Show / Hide
Range on Protein: 470-751
Range on HMM: 1-293/293
Sequence Identity: 34% (105 aa)

IEIQETVGQGEFGIVYRGVMT----SNTQMPKAVAVKTLKGFYKESDIDSLLDECIIM-MSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKE
  . .. | | || | ..       . ..   .|||| ||    . |. .|  |  .| |   . |.. |.|.|   || .|.|  . ..| |  .|.. 
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGP-LYVIVEYCHHGNLRDFLRAR

RPNLTVADTSEE-------DIILNV----------RKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYACNYFRQLKGSD
||    .. . .        .   .           |.| |.  ||| || ||| .| |||||||||  .  . |.|..||||. ||    |.|      
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRK-----

NNSGSSTVKLPVKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLD-PIGVVELLDTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSD
.  |     ||.||||.|.| |  .  .||||||||| ||.. .|  |||.        ..| .| |.  | |  |||||| .|  || ..| .|| |  
TTNG----RLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHN--CSQEIYHMMCQCWHFKPCQRPTFKQ

LVSSI
|| ..
LVEYL

Kinase AqueK385.AA Tec 652-753 46 4.7e-35 119.96 In-house 154-254 (254) Show / Hide
Range on Protein: 652-753
Range on HMM: 154-254/254
Sequence Identity: 46% (48 aa)

SST-VKLPVKWMALESLHDGLFSEKSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSDLVSS
||.  | |||| . | .|   .| |||||..||| |||||.||.||. .. . |||   .| ||  |    ||..||  |  ||.|.| .|| |..| ..
SSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPH--LCSMHIYQIMYHCWHEKPEERPTFQQLLRQ

INN
| .
ITE

Kinase AqueK385.AA S_TKc 470-755 20 6.7e-33 116.53 SMART 1-231 (231) Show / Hide
Range on Protein: 470-755
Range on HMM: 1-231/231
Sequence Identity: 20% (61 aa)

IEIQETVGQGEFGIVYRGVMTSNTQMPKAVAVKTLKGFYKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSR--GSLLSYLKKERPN
 || ...|.| || ||... ..     . ||.| .|        .... |  |... .  |.  |..|. |     |..| ...   |.|..|.|| ...
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTVADTSEEDIILNVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLSEDIYACNYFRQLKGSDNNSGSSTVKLPVKWM
     ..  ..              ... |..... |.  ...|||||   | ..|.  .||..||||.  .                  .|.     .|
GLRFPFPE-HAR-------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYM

ALESLHDGLFSE-KSDVWSYGVLCWEVFSLGKVPYPGLDPIGVVELLDTGGRLQCPYNGACSQEIYSLMMLCWSESPIDRPVFSDLVSSI-----NNLI
| | |    ..  |.|.|| |.. .| .. |. |.|      . ....  |          |.|  .... |.   | .||   ..  .         .
APEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK385.AA Tec 470-631 32 1.7e-31 107.35 In-house 1-144 (254) Show / Hide
Range on Protein: 470-631
Range on HMM: 1-144/254
Sequence Identity: 32% (54 aa)

IEIQETVGQGEFGIVYRGVMTSNTQMPKAVAVKTLK-GFYKESDIDSLLDECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRGSLLSYLKKERPNL
. . . .|.| ||.| .|  ... .    ||.|..| |   | |    ..|  .||     .   | |||.   |  ||.  .|..|.||.||....  .
LTFMKELGSGQFGVVHLGKWRHQYD----VAIKMIKEGSMSEED---FIEEAKVMMKLSHPKLVQLYGVCSQQRPI-YIVTEYMEHGCLLNYLREHKHHF

TVADTSEEDIILNVRKQ--LLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVIKVADFGLS
              ...  ||..|..|  || ||  ..||||||||||| .. ..|.||.|||..
Q-------------KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMT

Kinase AqueK385.AA Pkinase 470-707 24 4e-26 93.44 Pfam 1-229 (293) Show / Hide
Range on Protein: 470-707
Range on HMM: 1-229/293
Sequence Identity: 24% (63 aa)

IEIQETVGQGEFGIVYRGVMTSNTQMPKAVAVKTLKGFYKESDID--SLL-DECIIMMSFDNLNVLPLIGVCLDLGPAPYIIMPFMSRG----SLLSYLK
..| ...|.| || ||...  .. .    ||||..|   ..|. |   ..  |. || ...  |.. |.... | .. .|..|...  |    .| .|..
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

KERPNLTVADTSEEDIIL--NVRKQLLSICLQVANGMSYLALQKFIHRDLAARNCMIDNNGVI----KVADFGLSEDIYACNYFRQLKGSDNNSGSSTVK
            ...  .     ... ....|.. |. |.  ...|||||   |..|||||.|    |..||||.. ..            |||  .|. 
T-----------WRHGCFYFS-EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFC

LPVKWMALESLH-DGLFSEKSDVWSYGVLCWEVFSLGKVPYPGL------DPIGVVEL
    .|| | .  .   . |.|.||.|....|... |. |.||       |.. ....
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICR