Gene AqueK399 (A.queenslandica)

AqueK399

Species: A.queenslandica
Alias: AqueK399
External Links:
Annotation:

Classification

Group: TK
Family: Ret

Sequence

Name Sequence Type Origin Length Description Download
AqueK399.AA Protein None 352 None Fasta, JSON
AqueK399.kin_dom Protein Kinase Domain None 73 None Fasta, JSON

Protein domain

Protein domains of AqueK399.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK399.AA Pkinase_Tyr 254-326 42 2.1e-30 103.6 Pfam 198-270 (270) Show / Hide 
Range on Protein: 254-326
Range on HMM: 198-270/270
Sequence Identity: 42% (32 aa)

WSYGVMCWEVFSLGRVP-YPGLDPVGVVELL-DTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI
||.|| .||.|..|. | |||...  |.|.. . |.|.  | |  |..|||.||..|| . |.||| ||.... .
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK399.AA KIN6 254-326 44 5.6e-30 96.11 In-house 234-305 (305) Show / Hide 
Range on Protein: 254-326
Range on HMM: 234-305/305
Sequence Identity: 44% (33 aa)

WSYGVMCWEVFSLGRVPYPGLD-PVGVVELLDTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI
||.||. .|.|||| ||||..  |. . | .  |.|.  | .  |..|||  | |||.| ||||| |...   .
WSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKW--CPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK399.AA Tec 254-328 44 1.2e-28 97.3 In-house 182-254 (254) Show / Hide 
Range on Protein: 254-328
Range on HMM: 182-254/254
Sequence Identity: 44% (33 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLDTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSINA
|..||  |||||.|..||. .. . |||   .| ||| |  . ||..||  | .||.|.|..|| |..| ..|  
WAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRP--HLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase AqueK399.AA ALK 254-328 45 2.8e-28 94.72 In-house 201-273 (273) Show / Hide 
Range on Protein: 254-328
Range on HMM: 201-273/273
Sequence Identity: 45% (34 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLDTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSINA
||.|| |||.||||..||||     | |.. .|||.  | |  |   .| .|| ||   | ||| | ... .| .
WSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRN--CPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase AqueK399.AA TK 254-326 29 3.7e-28 90.87 In-house 378-486 (486) Show / Hide 
Range on Protein: 254-326
Range on HMM: 378-486/486
Sequence Identity: 29% (32 aa)

WSYGVMCWEVFSLGRVPYPGLDPV----------GVVELLDTGGR------------LYTPNNEACS--------------KEIYSLMTSCWSESPDDRP
||.||..||.|..|..||.|  .            |.|.| .|||            .  |  . |.              .|.| ||..||.. |.|||
WSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRP

VFSDLVSSI
 ||.|.. .
TFSQLHEQL
Kinase AqueK399.AA TK-Unique 254-326 40 7.2e-25 82.77 In-house 223-294 (294) Show / Hide 
Range on Protein: 254-326
Range on HMM: 223-294/294
Sequence Identity: 40% (30 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLDTGGRLYTPNNEAC-SKEIYSLMTSCWSESPDDRPVFSDLVSSI
||.||  ||.|.||  ||||...  ..|..  | |.  |..  | |.|.|.|| |||...|..|| |..... .
WSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH--CCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK399.AA UTK 254-326 42 9.3e-25 81.62 In-house 224-296 (296) Show / Hide 
Range on Protein: 254-326
Range on HMM: 224-296/296
Sequence Identity: 42% (31 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLDTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI
||.|| |||... ||.||||.  . |.. .  |||.  | ...|. ..| ||..||  .|..|| | |||. .
WSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK399.AA Ack 254-326 36 9.6e-24 76.97 In-house 195-266 (266) Show / Hide 
Range on Protein: 254-326
Range on HMM: 195-266/266
Sequence Identity: 36% (27 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLD-TGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI
|..||  ||.|| |. |. |. .  . ...|  | ||  |  ..|...||..|  || . | ||| ||...   
WMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRP--DCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase AqueK399.AA Sev 254-326 32 2.9e-23 74.2 In-house 207-277 (277) Show / Hide 
Range on Protein: 254-326
Range on HMM: 207-277/277
Sequence Identity: 32% (24 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLDTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVSSI
|..|. |||. .||  |||    . |     .||||  | .  |  .....|. ||  .|..|| |  .   .
WAFGILCWEIMTLGHQPYPAHSNFEVLNHVQAGGRLQQPRM--CPDDLWMMMRQCWRQDPWQRPSFHMCQNML
Kinase AqueK399.AA Syk 254-320 38 1.3e-22 74.69 In-house 193-257 (257) Show / Hide 
Range on Protein: 254-320
Range on HMM: 193-257/257
Sequence Identity: 38% (26 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLDTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFS
||.||  || ||.|  || .   . |..... | |.  |  . | .|.|.|| .||.. . ||| |.
WSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCP--NGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase AqueK399.AA Axl 254-324 42 3.5e-18 60.82 In-house 199-267 (267) Show / Hide 
Range on Protein: 254-324
Range on HMM: 199-267/267
Sequence Identity: 42% (30 aa)

WSYGVMCWEVFSLGRVPYPGLDPVGVVELLDTGGRLYTPNNEACSKEIYSLMTSCWSESPDDRPVFSDLVS
|..||  ||.   |. ||||..   . . |  | ||  |  | |  |.| || .||.  | ||| || |  
WAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQP--EDCMDELYDLMYQCWEADPKDRPSFSVLRE
Pkinase_Tyr AqueK399.AA Pkinase_Tyr 193-253 29 1.4e-12 43.22 Pfam 1-65 (270) Show / Hide 
Range on Protein: 193-253
Range on HMM: 1-65/270
Sequence Identity: 29% (19 aa)

INVQETAGQGEFGIVYRGVMT-RENQMPQPVAVKTLKGFYSKSD--VDSLLDECIIMMSF-DNLN
|   .. |.|.|| ||.|...  . .  .|||||.||  .....   .... |  ||... .. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPN
Kinase AqueK399.AA TyrKc 193-326 16 2.4e-12 -23.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 193-326
Range on HMM: 1-280/280
Sequence Identity: 16% (49 aa)

INVQETAGQGEFGIVYRGVMTRENQMPQPVAVKTLKGFYSKSDVDSLLDECIIMMSF-------------------------------------------
|   .. | |.||.||.|...      ..||||.||       .  ...|  ||...                                           
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

---------------------------------------------------------------D---------------NLN------------------
                                                               |               . .                  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

------WSYGVMCWEVFSLGRVPYPG-----LDPVGVVELLDTGGRLYTPNNEA------CSKEIYSLMTSCWSESPDDRPVFSDLVSSI
      ||.||..||.|..|  ||||     ...  |.|....|.|.  | |        |..|.|..|..|| | |.||| ||.... .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK399.AA TK-Unique 193-248 30 3.7e-10 31.33 In-house 1-59 (294) Show / Hide 
Range on Protein: 193-248
Range on HMM: 1-59/294
Sequence Identity: 30% (18 aa)

INVQETAGQGEFGIVYRGVMTREN---QMPQPVAVKTLKGFYSKSDVDSLLDECIIMMS
..|... |.|.|| |.|| ... .     .. ||||.||   .. |.. .|.|  .|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKE
Kinase AqueK399.AA TK 193-247 20 2.4e-09 26.68 In-house 1-93 (486) Show / Hide 
Range on Protein: 193-247
Range on HMM: 1-93/486
Sequence Identity: 20% (19 aa)

INVQETAGQGEFG---IVYRGVMTREN----------------------QMPQPVAVKTLKGFYSKSDVDSLL-------------DECIIMM
| . .. |.|.||    ||.| . ..|                      . ..|||||.||   . |. . ..              |. .|.
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMK
Kinase AqueK399.AA Ack 193-250 36 3.7e-07 20.19 In-house 1-60 (266) Show / Hide 
Range on Protein: 193-250
Range on HMM: 1-60/266
Sequence Identity: 36% (22 aa)

INVQETAGQGEFGIVYRGVMTRENQMPQPVAVKTLKGFYSKSD--VDSLLDECIIMMSFD
| . |  |.|.||.| ||. |  .    .|||| |.    ...   |..| |  ||.| |
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLD
Kinase AqueK399.AA Axl 193-250 32 5.4e-07 20.56 In-house 1-59 (267) Show / Hide 
Range on Protein: 193-250
Range on HMM: 1-59/267
Sequence Identity: 32% (19 aa)

INVQETAGQGEFGIVYRGVMTRENQMPQPVAVKTLK-GFYSKSDVDSLLDECIIMMSFD
. .  . |.|||| |  | .  |    . ||||..|    ..|...  | | . |  ||
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFD
Kinase AqueK399.AA Syk 193-251 23 2e-06 18.02 In-house 1-64 (257) Show / Hide 
Range on Protein: 193-251
Range on HMM: 1-64/257
Sequence Identity: 23% (15 aa)

INVQETAGQGEFGIVYRGVMTRE----NQMPQPVAVKTLK-GFYSKSDVDSLLDECIIMMSFDN
..  .  |.|.|| |  |.  .     .    .||.|.||  .  . | . .. |  .|.  |.
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKADHNQPADKQEFMREAQVMCQLDH
Kinase AqueK399.AA UTK 193-250 22 2e-06 17.94 In-house 1-67 (296) Show / Hide 
Range on Protein: 193-250
Range on HMM: 1-67/296
Sequence Identity: 22% (16 aa)

INVQETAGQGEFGIVYRGVMTREN-QMPQ-PVAVKTLKGFYSKSD----VD---SLLDECI---IMMSFD
.   .. |||.||.|...  |... .|..  ||||...   ...|     .    .. |.    .|. |.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFH
Kinase AqueK399.AA Pkinase 254-326 17 4.8e-05 18.92 Pfam 196-293 (293) Show / Hide 
Range on Protein: 254-326
Range on HMM: 196-293/293
Sequence Identity: 17% (17 aa)

WSYGVMCWEVFSLGRVPYPGL----DPVGVVELLDTGGR--LYTPNNEACS-------------------KEIYSLMTSCWSESPDDRPVFSDLVSS--I
||.|....|... || |.||     . .   ....  ..  |  .  . ||                   .|  .....|.   | .|| . ... .  .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK399.AA ALK 193-253 33 0.00012 11.98 In-house 1-63 (273) Show / Hide 
Range on Protein: 193-253
Range on HMM: 1-63/273
Sequence Identity: 33% (21 aa)

INVQETAGQGEFGIVYRGVMTR--ENQMPQPVAVKTLKGFYSKSDVDSLLDECIIMMSFDNLN
|      |.| || || |  .       | .||.|||.   |. |    . |  ||  |.  |
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQN
Kinase AqueK399.AA Sev 193-228 33 0.007723 5.1 In-house 1-39 (277) Show / Hide 
Range on Protein: 193-228
Range on HMM: 1-39/277
Sequence Identity: 33% (13 aa)

INVQETAGQGEFGIVYRGVMTREN---QMPQPVAVKTLK
       | | || || | .  .      .| ||.|||.
LKLRRFLGSGAFGEVYEGQAKDIDGVGEEEQRVAIKTLR
Kinase AqueK399.AA Pkinase 193-228 30 0.026079 9.25 Pfam 1-33 (293) Show / Hide 
Range on Protein: 193-228
Range on HMM: 1-33/293
Sequence Identity: 30% (11 aa)

INVQETAGQGEFGIVYRGVMTRENQMPQPVAVKTLK
. . .. |.| || ||...   ...    ||||..|
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIK